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Displaying drugs 226 - 250 of 5026 in total
Methimazole
Methimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones.[A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949 and is now commonly used in the management of hyperthyroidism, particularly in those for whom more aggressive options such as surgery or radioactive iodine therapy are inappropriate.[L8336,L8339]...
Approved
Matched Synonyms: … 1-Methylimidazole-2(3H)-thione …
Matched Iupac: … 1-methyl-2,3-dihydro-1H-imidazole-2-thione …
Matched Description: … Methimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones. ... [L8336,L8339] On a weight basis, methimazole is 10 times more potent than the other major antithyroid ... hepatotoxicity carried by the latter,[A184757] with propylthiouracil being preferred in pregnancy due to a …
Matched Categories: … Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Iupac: … 1-methyl-2,3-dihydro-1H-imidazole-2-thione …
Matched Description: … Methimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones. ... [L8336,L8339] On a weight basis, methimazole is 10 times more potent than the other major antithyroid ... hepatotoxicity carried by the latter,[A184757] with propylthiouracil being preferred in pregnancy due to a …
Matched Categories: … Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Chlorzoxazone
A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
Approved
Matched Synonyms: … 5-chloro-2-benzoxazolol ... 5-chloro-2-benzoxazolone ... 5-chloro-2-benzoxazolinone …
Matched Iupac: … 5-chloro-2,3-dihydro-1,3-benzoxazol-2-one …
Matched Description: … A centrally acting central muscle relaxant with sedative properties. ... is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and …
Matched Mixtures name: … Extra Strength Tylenol Aches and Strains …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Benzoxazoles and derivatives ... Oxazol, Thiazine, and Triazine Derivatives …
Matched Iupac: … 5-chloro-2,3-dihydro-1,3-benzoxazol-2-one …
Matched Description: … A centrally acting central muscle relaxant with sedative properties. ... is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and …
Matched Mixtures name: … Extra Strength Tylenol Aches and Strains …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Benzoxazoles and derivatives ... Oxazol, Thiazine, and Triazine Derivatives …
Zalcitabine
A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the elongation of DNA chains, thus resulting in the termination of viral DNA growth. The compound is...
Approved
Investigational
Matched Synonyms: … 2',3'-Dideoxycytidine ... 4-amino-1-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2(1H)-one …
Matched Iupac: … 4-amino-1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by ... a hydrogen. ... This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Matched Iupac: … 4-amino-1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by ... a hydrogen. ... This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Indacaterol
Indacaterol is a novel, ultra-long-acting, rapid onset β(2)-adrenoceptor agonist developed for Novartis for the once-daily management of asthma and chronic obstructive pulmonary disease. It was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011. It is marketed in Europe as...
Approved
Matched Iupac: … -2-one ... 5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-1,2-dihydroquinolin …
Matched Description: … Indacaterol is a novel, ultra-long-acting, rapid onset β(2)-adrenoceptor agonist developed for Novartis ... It was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011 ... Indacaterol is also a chiral molecule but only the pure R-enantiomer is dispensed. …
Matched Salts cas: … 1000160-96-2 …
Matched Categories: … indacaterol and mometasone ... Adrenergic beta-2 Receptor Agonists ... Heterocyclic Compounds, 2-Ring ... Selective Beta 2-adrenergic Agonists ... indacaterol and glycopyrronium bromide …
Matched Description: … Indacaterol is a novel, ultra-long-acting, rapid onset β(2)-adrenoceptor agonist developed for Novartis ... It was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011 ... Indacaterol is also a chiral molecule but only the pure R-enantiomer is dispensed. …
Matched Salts cas: … 1000160-96-2 …
Matched Categories: … indacaterol and mometasone ... Adrenergic beta-2 Receptor Agonists ... Heterocyclic Compounds, 2-Ring ... Selective Beta 2-adrenergic Agonists ... indacaterol and glycopyrronium bromide …
Alfacalcidol
Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of vitamin D. It plays an essential function in calcium homeostasis and bone metabolism. Alfacaldisol is activated by the enzyme 25-hydroxylase in the liver to mediate its effects in the body, or most importantly, the kidneys and bones. The pharmacological...
Approved
Nutraceutical
Matched Iupac: … (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-octahydro-1H-inden-4-ylidene] …
Matched Description: … Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue ... The pharmacological actions of alfacalcidol are prolonged than vitamin D because a negative feedback ... malabsorptive rickets and osteomalacia, vitamin D-dependent rickets and osteomalacia, and hypophosphataemic …
Matched Categories: … Vitamin D and Analogues ... Alimentary Tract and Metabolism ... alendronic acid and alfacalcidol, sequential ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Etalpha 2 µg - Ampullen ... ONE-ALPHA DROPS 2 mcg/ml ... EINSALPHA 2 UG/ML TROPFEN …
Matched Description: … Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue ... The pharmacological actions of alfacalcidol are prolonged than vitamin D because a negative feedback ... malabsorptive rickets and osteomalacia, vitamin D-dependent rickets and osteomalacia, and hypophosphataemic …
Matched Categories: … Vitamin D and Analogues ... Alimentary Tract and Metabolism ... alendronic acid and alfacalcidol, sequential ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Etalpha 2 µg - Ampullen ... ONE-ALPHA DROPS 2 mcg/ml ... EINSALPHA 2 UG/ML TROPFEN …
Pentobarbital
A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA...
Approved
Investigational
Vet approved
Matched Iupac: … 5-ethyl-5-(pentan-2-yl)-1,3-diazinane-2,4,6-trione …
Matched Description: … A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) ... agent and is usually given orally. …
Matched Categories: … Hypnotics and Sedatives …
Matched Description: … A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) ... agent and is usually given orally. …
Matched Categories: … Hypnotics and Sedatives …
Prednisone
A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver. Prednisone was granted FDA approval on 21 February 1955.
Approved
Vet approved
Matched Iupac: … ,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-7,10-dione ... (1R,3aS,3bS,9aR,9bS,11aS)-1-hydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH …
Matched Description: … A synthetic anti-inflammatory glucocorticoid derived from [cortisone]. ... [A187463] It is biologically inert and converted to [prednisolone] in the liver. …
Matched Categories: … Alimentary Tract and Metabolism ... Prednisolone and Prodrugs ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … ROMEZON DR 2 MG TABLET, 30 ADET …
Matched Description: … A synthetic anti-inflammatory glucocorticoid derived from [cortisone]. ... [A187463] It is biologically inert and converted to [prednisolone] in the liver. …
Matched Categories: … Alimentary Tract and Metabolism ... Prednisolone and Prodrugs ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … ROMEZON DR 2 MG TABLET, 30 ADET …
Amitriptyline
Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.
Approved
Matched Synonyms: … 5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene ... 5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptatriene ... 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine …
Matched Iupac: … dimethyl(3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene}propyl)amine …
Matched Description: … ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961 ... Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. …
Matched Salts cas: … 17086-03-2 …
Matched Mixtures name: … Etrafon A Tab ... Apo Peram Tab 3-15 ... PMS-levazine 3/15 Tab …
Matched Categories: … amitriptyline and psycholeptics ... Tricyclics and Other Norepinephrine-reuptake Inhibitors ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … dimethyl(3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene}propyl)amine …
Matched Description: … ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961 ... Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. …
Matched Salts cas: … 17086-03-2 …
Matched Mixtures name: … Etrafon A Tab ... Apo Peram Tab 3-15 ... PMS-levazine 3/15 Tab …
Matched Categories: … amitriptyline and psycholeptics ... Tricyclics and Other Norepinephrine-reuptake Inhibitors ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index …
Zaleplon
Zaleplon is a sedative/hypnotic, mainly used for insomnia. It is known as a nonbenzodiazepine hypnotic. Zaleplon interacts with the GABA receptor complex and shares some of the pharmacological properties of the benzodiazepines. Zaleplon is a schedule IV drug in the United States.
Approved
Illicit
Investigational
Matched Synonyms: … 3'-(3-Cyanopyrazolo(1,5-a)pyrimidin-7-yl)-N-ethylacetanilide …
Matched Iupac: … N-(3-{3-cyanopyrazolo[1,5-a]pyrimidin-7-yl}phenyl)-N-ethylacetamide …
Matched Description: … Zaleplon interacts with the GABA receptor complex and shares some of the pharmacological properties of ... It is known as a nonbenzodiazepine hypnotic. ... Zaleplon is a sedative/hypnotic, mainly used for insomnia. …
Matched Categories: … GABA-A Receptor Agonists ... gamma-Aminobutyric Acid A Receptor Agonist ... Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Iupac: … N-(3-{3-cyanopyrazolo[1,5-a]pyrimidin-7-yl}phenyl)-N-ethylacetamide …
Matched Description: … Zaleplon interacts with the GABA receptor complex and shares some of the pharmacological properties of ... It is known as a nonbenzodiazepine hypnotic. ... Zaleplon is a sedative/hypnotic, mainly used for insomnia. …
Matched Categories: … GABA-A Receptor Agonists ... gamma-Aminobutyric Acid A Receptor Agonist ... Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Omega-3-carboxylic acids
The omega-3 carboxylic acid (OM3-CA) is a new formulation of omega-3 fatty acids that present an enhanced bioavailability in the treatment of dyslipidemia. The increased bioavailability is explained because OM3-CA is found in a form of polyunsaturated free fatty acids as opposed to other products whose form is as ethyl...
Approved
Investigational
Matched Synonyms: … Omega-3-carboxylic acids …
Matched Name: … Omega-3-carboxylic acids …
Matched Description: … The omega-3 carboxylic acid (OM3-CA) is a new formulation of omega-3 fatty acids that present an enhanced ... [A25808] It was developed by AstraZeneca Pharmaceuticals and firstly approved by the FDA on May 05, 2014 ... acid as the most abundant species found in a proportion of 55% and 20% respectively. …
Matched Categories: … Fatty Acids, Omega-3 …
Matched Name: … Omega-3-carboxylic acids …
Matched Description: … The omega-3 carboxylic acid (OM3-CA) is a new formulation of omega-3 fatty acids that present an enhanced ... [A25808] It was developed by AstraZeneca Pharmaceuticals and firstly approved by the FDA on May 05, 2014 ... acid as the most abundant species found in a proportion of 55% and 20% respectively. …
Matched Categories: … Fatty Acids, Omega-3 …
Varicella zoster vaccine (recombinant)
Recombinant zoster vaccine, manufactured as the product Shingrix by GlaxoSmithKline, is an adjuvanted non-live recombinant vaccine indicated for prevention of shingles. First approved in October 2017 by the Food and Drug Administration, Shingrix is the preferred vaccine for preventing varicella zoster infection in people aged 50 years and older, replacing...
Approved
Investigational
Matched Description: … First approved in October 2017 by the Food and Drug Administration, Shingrix is the preferred vaccine ... Following initial infection of VZV and resolution of Chickenpox as a child, VZV then lies dormant within ... through the nerve cells to the surface of the skin where it causes a painful blistering rash. …
Matched Products: … SHINGRIX POWDER AND SUSPENSION FOR SUSPENSION FOR INJECTION 50MCG/0.5ML …
Matched Products: … SHINGRIX POWDER AND SUSPENSION FOR SUSPENSION FOR INJECTION 50MCG/0.5ML …
Inositol
Inositol is a collection of nine different stereoisomers but the name is usually used to describe only the most common type of inositol, myo-inositol. Myo-inositol is the cis-1,2,3,5-trans-4,6-cyclohexanehexol and it is prepared from an aqueous extract of corn kernels by precipitation and hydrolysis of crude phytate. These molecules have structural...
Approved
Investigational
Withdrawn
Matched Description: … It is considered a pseudovitamin as it is a molecule that does not qualify to be an essential vitamin ... of corn kernels by precipitation and hydrolysis of crude phytate. ... These molecules have structural similarities to glucose and are involved in cellular signaling. …
Matched Mixtures name: … For-2 ... Stom #2 ... Spectrum 2 Cap …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Mixtures name: … For-2 ... Stom #2 ... Spectrum 2 Cap …
Matched Categories: … Alimentary Tract and Metabolism …
Budesonide
Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532]
Budesonide was granted FDA approval on 14 February 1994. It is also available in a combination product...
Approved
Matched Iupac: … (1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo …
Matched Description: … Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions ... of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis. ... [L10598] It is also available in a combination product with [formoterol].[L10619] …
Matched Mixtures name: … POENA 2/400 MCG İNHALASYON İÇİN TOZ İÇEREN BLİSTER, 60 DOZ ... POENA 2/400 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL ,60 KAPSÜL ... POENA 2/400 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL ,120 KAPSÜL …
Matched Categories: … Alimentary Tract and Metabolism ... salbutamol and budesonide ... formoterol and budesonide ... salmeterol and budesonide ... formoterol, glycopyrronium bromide and budesonide …
Matched Products: … ENTOCORT(R)2 MG ... BUDENOFALK 3 MG CAPSULE ... BUDENOFALK CAPSULE 3 mg …
Matched Description: … Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions ... of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis. ... [L10598] It is also available in a combination product with [formoterol].[L10619] …
Matched Mixtures name: … POENA 2/400 MCG İNHALASYON İÇİN TOZ İÇEREN BLİSTER, 60 DOZ ... POENA 2/400 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL ,60 KAPSÜL ... POENA 2/400 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL ,120 KAPSÜL …
Matched Categories: … Alimentary Tract and Metabolism ... salbutamol and budesonide ... formoterol and budesonide ... salmeterol and budesonide ... formoterol, glycopyrronium bromide and budesonide …
Matched Products: … ENTOCORT(R)2 MG ... BUDENOFALK 3 MG CAPSULE ... BUDENOFALK CAPSULE 3 mg …
Ombitasvir
Ombitasvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Synonyms: … -(4-tert-butylphenyl)pyrrolidine-2,5-diyl]bis{(4,1-phenylene)carbamoyl(2S)pyrrolidine-2,1-diyl[(2S)-3- …
Matched Iupac: … ]-3-methylbutanoyl]pyrrolidine-2-amido]phenyl}pyrrolidin-2-yl]phenyl}carbamoyl)pyrrolidin-1-yl]-3-methyl ... -1-oxobutan-2-yl]carbamate ... methyl N-[(2S)-1-[(2S)-2-({4-[(2S,5S)-1-(4-tert-butylphenyl)-5-{4-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino …
Matched Description: … FDA- and Health Canada-approved product Technivie. ... , and [DB00503] as the Health Canada-approved, commercially available product Holkira Pak. ... Ombitasvir is an inhibitor of NS5A, a protein essential for viral replication and virion assembly [FDA …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ombitasvir, paritaprevir and ritonavir ... dasabuvir, ombitasvir, paritaprevir and ritonavir …
Matched Iupac: … ]-3-methylbutanoyl]pyrrolidine-2-amido]phenyl}pyrrolidin-2-yl]phenyl}carbamoyl)pyrrolidin-1-yl]-3-methyl ... -1-oxobutan-2-yl]carbamate ... methyl N-[(2S)-1-[(2S)-2-({4-[(2S,5S)-1-(4-tert-butylphenyl)-5-{4-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino …
Matched Description: … FDA- and Health Canada-approved product Technivie. ... , and [DB00503] as the Health Canada-approved, commercially available product Holkira Pak. ... Ombitasvir is an inhibitor of NS5A, a protein essential for viral replication and virion assembly [FDA …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ombitasvir, paritaprevir and ritonavir ... dasabuvir, ombitasvir, paritaprevir and ritonavir …
Penbutolol
Penbutolol is a drug in the beta-blocker class used to treat hypertension. Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker. Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric drug. Penbutolol also demonstrates high binding affinity to the...
Approved
Investigational
Matched Synonyms: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Iupac: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Description: … Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker ... Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric ... Penbutolol is a drug in the beta-blocker class used to treat hypertension. …
Matched Categories: … penbutolol and other diuretics …
Matched Iupac: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Description: … Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker ... Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric ... Penbutolol is a drug in the beta-blocker class used to treat hypertension. …
Matched Categories: … penbutolol and other diuretics …
Dexbrompheniramine
Dexbrompheniramine maleate is an antihistamine agent that is used for the treatment of allergic conditions, such as hay fever or urticaria.
Approved
Matched Synonyms: … (R)-3-(4-Bromophenyl)-3-(2-pyridyl)propyldimethylamine ... 3-(4-bromophenyl)- N,N-dimethyl- 3-pyridin-2-yl-propan-1-amine …
Matched Iupac: … [(3S)-3-(4-bromophenyl)-3-(pyridin-2-yl)propyl]dimethylamine …
Matched Mixtures name: … Supress A ... Dexbrompheniramine-DM-Phenylephrine 2-15-7.5 ... Coricidin 'd' Nasal and Sinus Congestion …
Matched Iupac: … [(3S)-3-(4-bromophenyl)-3-(pyridin-2-yl)propyl]dimethylamine …
Matched Mixtures name: … Supress A ... Dexbrompheniramine-DM-Phenylephrine 2-15-7.5 ... Coricidin 'd' Nasal and Sinus Congestion …
Protriptyline
Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, protriptyline does not affect mood or arousal, but may cause sedation. In depressed individuals, protriptyline exerts a positive...
Approved
Matched Synonyms: … 5-(3-methylaminopropyl)-5H-dibenzo[a,d]cycloheptene ... 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine ... 3-(5H-dibenzo[a,d]cyclohepten-5-yl)-N-methyl-1-propanamine …
Matched Iupac: … methyl(3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-yl}propyl)amine …
Matched Description: … TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... See toxicity section below for a complete listing of side effects. ... In depressed individuals, protriptyline exerts a positive effect on mood. …
Matched Iupac: … methyl(3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-yl}propyl)amine …
Matched Description: … TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... See toxicity section below for a complete listing of side effects. ... In depressed individuals, protriptyline exerts a positive effect on mood. …
Desonide
A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses.
Approved
Investigational
Matched Iupac: … (1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[ …
Matched Description: … A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses. …
Matched Mixtures name: … PRECORT-A KREM ... PRECORT-A POMAD ... PREDNOL-A 30 GR KREM …
Matched Categories: … desonide and antiseptics …
Matched Description: … A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses. …
Matched Mixtures name: … PRECORT-A KREM ... PRECORT-A POMAD ... PREDNOL-A 30 GR KREM …
Matched Categories: … desonide and antiseptics …
Mirvetuximab soravtansine
Mirvetuximab soravtansine-gynx (IMGN853) is an antibody-drug conjugate (ADC) formed by a monoclonal antibody (M9346A) that targets folate receptor alpha (FRα), covalently joined by a cleavable disulfide linker to the genotoxic compound DM4 (also known as soravtansine or ravtansine).[A254392,L43967] DM4 is conjugated to the antibody with a drug-to-antibody ratio of 3.5:1....
Approved
Investigational
Matched Description: … DM4 leads to cell-cycle arrest and apoptosis and is also able to diffuse into neighboring cells and induce ... This decision was supported by findings from the phase 3 SORAYA trial (NCT04296890). ... platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer who have received 1-3 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Clobazam
Clobazam belongs to the 1,5-benzodiazepine class of drugs and is marketed under different names, Onfi, Frisium, Urbanyl, and others. . Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. Unlike older 1,4-benzodiazepines, clobazam has...
Approved
Illicit
Matched Description: … [A256963,A256868] This is likely because of clobazam's higher affinity to the α2 subunit of ... [A521,A522] In October 21, 2011, the FDA approved clobazam as an adjunctive treatment for seizures associated ... [A256868] Additionally, clobazam is believed to be a partial agonist to the GABAA receptor …
Matched Categories: … GABA-A Receptor Agonists ... Heterocyclic Compounds, 2-Ring ... Benzodiazepines and benzodiazepine derivatives …
Matched Categories: … GABA-A Receptor Agonists ... Heterocyclic Compounds, 2-Ring ... Benzodiazepines and benzodiazepine derivatives …
Lixisenatide
Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM). It is sold by Sanofi-Aventis under the brand name Adlyxin in the US and Lyxumia in the EU. Adlyxin recieved FDA approval July 28, 2016.
Approved
Matched Description: … It is sold by Sanofi-Aventis under the brand name Adlyxin in the US[L763] and Lyxumia in the EU. ... Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes …
Matched Mixtures name: … LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) ... LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) ... SOLİQUA SOLOSTAR 100 U/ML + 33 MCG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 3 KALEM …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin glargine and lixisenatide …
Matched Products: … LYXUMIA 20 MCG ENJEKSIYON IÇIN ÇÖZELTI IÇEREN KULLANIMA HAZIR KALEM ,2 KALEM …
Matched Mixtures name: … LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) ... LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) ... SOLİQUA SOLOSTAR 100 U/ML + 33 MCG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 3 KALEM …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin glargine and lixisenatide …
Matched Products: … LYXUMIA 20 MCG ENJEKSIYON IÇIN ÇÖZELTI IÇEREN KULLANIMA HAZIR KALEM ,2 KALEM …
Omaveloxolone
Omaveloxolone (RTA-408) is a semisynthetic oleanane triterpenoid with antioxidant and anti-inflammatory properties.[A257534,A257539] Omaveloxolone acts as an activator of nuclear factor (erythroid-derived 2)-like 2 (Nrf2), a transcription factor that mitigates oxidative stress. In patients with Friedreich's ataxia, a genetic disease involving mitochondrial dysfunction, the Nrf2 pathway is impaired, and Nrf2 activity...
Approved
Investigational
Matched Synonyms: … Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro- …
Matched Description: … Omaveloxolone (RTA-408) is a semisynthetic oleanane triterpenoid with antioxidant and anti-inflammatory ... [A257534,A257539] Omaveloxolone acts as an activator of nuclear factor (erythroid-derived 2)-like 2 ( ... [A257529] In February 2023, omaveloxolone was approved by the FDA for the treatment of Friedreich's ataxia …
Matched Description: … Omaveloxolone (RTA-408) is a semisynthetic oleanane triterpenoid with antioxidant and anti-inflammatory ... [A257534,A257539] Omaveloxolone acts as an activator of nuclear factor (erythroid-derived 2)-like 2 ( ... [A257529] In February 2023, omaveloxolone was approved by the FDA for the treatment of Friedreich's ataxia …
Altretamine
An alkylating agent proposed as an antineoplastic. It also acts as a chemosterilant for male houseflies and other insects.
Approved
Matched Description: … It also acts as a chemosterilant for male houseflies and other insects. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Chlorphenesin
Approved
Experimental
Matched Synonyms: … 3-(4-chlorophenoxy)-1,2-propanediol ... 3-(p-chlorophenoxy)-1,2-propanediol ... 3-(p-chlorophenoxy)propane-1,2-diol …
Matched Iupac: … 3-(4-chlorophenoxy)propane-1,2-diol …
Matched Iupac: … 3-(4-chlorophenoxy)propane-1,2-diol …
Ensulizole
Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. Due to its water solubility, ensulizole is commonly...
Approved
Matched Iupac: … 2-phenyl-1H-1,3-benzodiazole-6-sulfonic acid …
Matched Description: … Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that ... According to the FDA, the maximal approved concentration of ensulizole is 148 mM although concentrations ... compounds due to its minimal protection against UV-A wavelengths. …
Matched Mixtures name: … Shiseido Urban Environment Tinted Uv Protector 3 ... Hawaiian Tropic Herbal Tanning Mist 2 SPF ... Shiseido Urban Environment Tinted Uv Protector 2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Sungirl SPF 3 ... Covergirl Outlast All Day Stay Fabulous 3-IN-1 Foundation ... Dolce and Gabbana The Foundation Perfect Matte Broadspectrum SPF 20 All shades …
Matched Description: … Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that ... According to the FDA, the maximal approved concentration of ensulizole is 148 mM although concentrations ... compounds due to its minimal protection against UV-A wavelengths. …
Matched Mixtures name: … Shiseido Urban Environment Tinted Uv Protector 3 ... Hawaiian Tropic Herbal Tanning Mist 2 SPF ... Shiseido Urban Environment Tinted Uv Protector 2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Sungirl SPF 3 ... Covergirl Outlast All Day Stay Fabulous 3-IN-1 Foundation ... Dolce and Gabbana The Foundation Perfect Matte Broadspectrum SPF 20 All shades …
Displaying drugs 226 - 250 of 5026 in total