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Displaying drugs 251 - 275 of 14774 in total
Ergocalciferol is an inactivated vitamin D analog. It is synthesized by some plants in the presence of UVB light. The production of ergocalciferol was prompted by the identification of dietary deficiency, more specifically vitamin D, as the main causative factor for the development of rickets. Ergocalciferol was isolated for the...
Approved
Nutraceutical
Matched Description: … ] by the presence of a double bond between C22 and C23 and the presence of a methyl group at C24. ... Ergocalciferol was isolated for the first time from yeast in 1931 and its structure was elucidated in ... approved product containing ergocalciferol under the FDA records was developed by US Pharm Holdings and
Matched Mixtures name: … Vitamin D2 and K1 ... Calcium With Vitamins C and D Tab ... SAFWA HEALTH CALCIUM AND VITAMIN D …
Matched Categories: … Diet, Food, and Nutrition ... Vitamin D and Analogues ... Alimentary Tract and Metabolism ... Calcium-Regulating Hormones and Agents …
Guinea pig hair is used in allergenic testing.
Approved
Matched Mixtures name: … Guinea Pig Hair and Epithelia ... Animal Allergens, Guinea Pig Hair and Dander ... Animal Allergens, Guinea Pig Hair and Dander …
Equus caballus dander is the dander of Equus caballus. Equus caballus dander is used in allergenic testing.
Approved
Matched Mixtures name: … Animal Allergens, AP Horse Hair and Dander ... Animal Allergens, AP Horse Hair and Dander ... Animal Allergens, AP Horse Hair and Dander …
Lopinavir is an antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 infection. Lopinavir is marketed and administered exclusively in combination with ritonavir - this combination, first marketed by Abbott under the brand name Kaletra in 2000, is necessary due to lopinavir's poor oral bioavailability...
Approved
Matched Description: … "boosts" lopinavir exposure and improves antiviral activity. ... Abbott under the brand name Kaletra in 2000, is necessary due to lopinavir's poor oral bioavailability and ... [L11163] Lopinavir is marketed and administered exclusively in combination with [ritonavir] - this combination …
Matched Mixtures name: … Lopinavir and Ritonavir ... Lopinavir and ritonavir ... Lopinavir and ritonavir …
Matched Categories: … lopinavir and ritonavir ... Metabolic Side Effects of Drugs and Substances …
Potassium citrate (also known as tripotassium citrate) is a potassium salt of citric acid. It is a white, hygroscopic crystalline powder. It is odorless with a saline taste. It contains 38.3% potassium by mass. In the monohydrate form it is highly hygroscopic and deliquescent. Potassium citrate is used to treat...
Approved
Investigational
Vet approved
Matched Description: … In the monohydrate form it is highly hygroscopic and deliquescent. …
Matched Mixtures name: … Calcium and Mag-potass and Zinc Cap ... Potassium Citrate and Citric Acid ... Children's Chewable Vit and Min Tab …
Matched Categories: … Alimentary Tract and Metabolism …
Dichloralphenazone is a sedative composed of chloral hydrate and phenazone. It is typically found in combination products Nodolor and Midrin containing isometheptene and acetaminophen used for the relief of tension and vascular headaches. It is a US Schedule IV drug and its clinical use is limited.
Approved
Illicit
Matched Description: … It is typically found in combination products Nodolor and Midrin containing [isometheptene] and [acetaminophen ... ] used for the relief of tension and vascular headaches. ... It is a US Schedule IV drug and its clinical use is limited. …
Matched Mixtures name: … Isometheptene Mucate, Dichloralphenazone, and Acetaminophen ... Isometheptene Mucate, Dichloralphenazone, and Acetaminophen ... Isometheptene Mucate, Dichloralphenazone, and Acetaminophen …
Matched Categories: … Hypnotics and Sedatives …
Estradiol Valerate (also known as E2V) is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol acetate therefore...
Approved
Investigational
Vet approved
Matched Description: … Because of the difference in potency between estradiol and estrone, menopause (and a change in primary ... a chance to enter systemic circulation and exert its estrogenic effects [A12102]. ... Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex …
Matched Mixtures name: … Estradiol Valerate and Estradiol Valerate/Dienogest ... Estradiol Valerate and Estradiol Valerate/Dienogest ... Estradiol Valerate and Estradiol Valerate/Dienogest …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Poa compressa pollen is the pollen of the Poa compressa plant. Poa compressa pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Mixture of Standardized and Non-Standardized Inland Grasses ... Mixture of Twenty-Two Standardized and Non-Standardized Grasses ... Mixture of Standardized and Non-Standardized Coastal Grasses …
A preparation of methionine that includes a mixture of D-methionine and L-methionine isomers.
Approved
Experimental
Matched Description: … A preparation of methionine that includes a mixture of D-methionine and L-methionine isomers. …
Matched Mixtures name: … Swiss One Multivitamin and Mineral Caplet ... Vita Vim Multivitamins and Minerals Tab ... Super Vita Vim Multivitamins and Minerals …
Matched Categories: … Amino Acids, Peptides, and Proteins …
A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of...
Approved
Withdrawn
Matched Description: … in fertilizers and explosives. ... that supply 100 mg or more of potassium per dosage unit, except for controlled-release dosage forms and ... crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and
Matched Mixtures name: … Plasma-Lyte 148 and dextrose ... Ringers and Dextrose ... Ionosol and Dextrose …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Cortisone acetate was first isolate in 1935 and became more widely researched in 1949. Since then, glucocorticoids such as cortisone acetate have been used to treat a number of inflammatory conditions such as endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, and gastrointestinal diseases and disorders.[A226300,L13203] Cortisone acetate...
Approved
Investigational
Matched Description: … gastrointestinal diseases and disorders. ... Cortisone acetate was first isolate in 1935 and became more widely researched in 1949. ... rheumatic, collagen, dermatologic, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, and
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Vericiguat is a direct stimulator of soluble guanylate cyclase (sGC) used in the management of systolic heart failure to reduce mortality and hospitalizations. A key component of the NO-sGC-cGMP signaling pathway that helps to regulate the cardiovascular system, sGC enzymes are intracellular enzymes found in vascular smooth muscle cells (amongst...
Approved
Investigational
Matched Iupac: … methyl N-(4,6-diamino-2-{5-fluoro-1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl}pyrimidin …
Matched Description: … soluble guanylate cyclase (sGC) used in the management of systolic heart failure to reduce mortality and ... thereby helps to prevent the myocardial and vascular dysfunction associated with decreased sGC activity ... messenger, activating a number of downstream signaling cascades that elicit a broad variety of effects, and
Renal cell carcinoma (RCC) is responsible for 3% of cancer cases and is one of the 10 most common cancers in adults. The average age of diagnosis is between age 65 to 74. Tivozanib, also known as FOTIVDA, is a kinase inhibitor developed to treat adult patients with relapsed or...
Approved
Investigational
Matched Description: … Renal cell carcinoma (RCC) is responsible for 3% of cancer cases[A231314] and is one of the 10 most common …
Matched Salts name: … Tivozanib hydrochloride
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form. Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used commercially...
Approved
Investigational
Matched Description: … Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used …
Matched Mixtures name: … Antacid and Antigas ... Mylanta Coat and Cool ... Antacid and Gasrelief …
Matched Categories: … Antacids and Adsorbents ... Alimentary Tract and Metabolism ... Basic Ointments and Protectants ... Emollients Demulcents and Protectants ... Aluminum and magnesium containing antacids …
Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD.[L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 adrenergic receptor agonist, salbutamol. Salmeterol was first described in the literature in 1988. Salmeterol's structure...
Approved
Matched Description: … long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and
Matched Mixtures name: … Fluticasone Propionate and Salmeterol ... Fluticasone Propionate and Salmeterol ... Fluticasone Propionate and Salmeterol …
Matched Categories: … salmeterol and budesonide ... salmeterol and fluticasone …
Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Matched Description: … C23 and has an additional methyl group at C24 [L5689]. ... the plant-derived form, vitamin D2 (ergocalciferol), are considered the main forms of vitamin d and ... of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and
Matched Mixtures name: … Hvp Chelated Cal/mag With Zinc and Vitamins C and D ... Calcium and Magnesium Citrate and Vitamin D 250mg/125mg/200iu ... Multi Vitamin and Fluoride …
Matched Categories: … Alimentary Tract and Metabolism ... Vitamin D and Analogues ... Diet, Food, and Nutrition ... Calcium-Regulating Hormones and Agents ... ibandronic acid and colecalciferol …
Aluminum hydroxide is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects.
Approved
Investigational
Matched Description: … An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. …
Matched Mixtures name: … Antacid and Antigas ... Antacid and Gasrelief ... Antacid and Gasrelief …
Matched Categories: … Antacids and Adsorbents ... Alimentary Tract and Metabolism ... Aluminum and magnesium containing antacids …
Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to coat the tips of hunting arrows and darts, which were typically derived from plants of the genera Chondrodendron and Strychnos....
Approved
Matched Description: … number of plant-derived alkaloids, including [morphine] and [papaverine]. ... Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid ... darts, which were typically derived from plants of the genera _Chondrodendron_ and _Strychnos_. …
Nilotinib, also known as AMN107, is a tyrosine kinase inhibitor under investigation as a possible treatment for chronic myelogenous leukemia (CML). A Phase I clinical trial in 2006 showed that this drug was relatively safe and offered significant therapeutic benefits in cases of CML which were found to be resistant...
Approved
Investigational
Matched Iupac: … 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-{[4-(pyridin-3-yl)pyrimidin-2- …
Matched Description: … A Phase I clinical trial in 2006 showed that this drug was relatively safe and offered significant therapeutic …
Matched Salts name: … Nilotinib hydrochloride monohydrate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Apalutamide is a potent androgen receptor (AR) antagonist that selectively binds to the ligand-binding domain of AR and blocks AR nuclear translocation or binding to androgen response elements . It has been used in trials studying the treatment of Prostate Cancer, Hepatic Impairment, Prostatic Neoplasms, Castration-Resistant Prostate Cancer, and Prostatic...
Approved
Investigational
Matched Iupac: … 4-{7-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl}-2 …
Matched Description: … It targets the AR ligand-binding domain and prevents AR nuclear translocation, DNA binding, and transcription ... risk for metastases and death [A31846]. ... Apalutamide displayed good tolerability and safety profile in clinical studies. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Remimazolam is an ultra short-acting benzodiazepine used in the induction and maintenance of sedation during short (<30 minute) procedures. Recent trends in anesthesia-related drug development have touted the benefits of so-called "soft drugs" - these agents, such as remifentanil, are designed to be metabolically fragile and thus susceptible to rapid...
Approved
Investigational
Matched Iupac: … methyl 3-[(7S)-12-bromo-3-methyl-9-(pyridin-2-yl)-2,5,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(14), …
Matched Description: … thus susceptible to rapid biotransformation and elimination as inactive metabolites. ... Remimazolam is an ultra short-acting benzodiazepine used in the induction and maintenance of sedation ... [A214852,A214857] Remimazolam was the first "soft" benzodiazepine analog to be developed[A214862] and
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives …
Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Nutraceutical
Vet approved
Matched Description: … d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and ... At the moment however, there exists a lack of formal data and evidence to support any such additional ... This biologic action of vitamin E consequently continues to generate ongoing interest and study in whether …
Matched Mixtures name: … Multi Vitamin and Mineral vitamin ... Iron With Vitamins C and E - Tab ... Vita Vim Multivitamins and Minerals Tab …
Matched Categories: … Diet, Food, and Nutrition …
Estrone sulfate (as estropipate) is a form of estrogen. It has several uses such as: alleviate symptoms of menopause as hormone replacement therapy, treatment some types of infertility, treatment of some conditions leading to underdevelopment of female sexual characteristics, treatment of vaginal atrophy, treatment of some types of breast cancer...
Approved
Matched Description: … postmenopausal women), treatment of prostate cancer and prevention of osteoporosis. ... characteristics, treatment of vaginal atrophy, treatment of some types of breast cancer (particularly in men and
Matched Mixtures name: … Esterified Estrogens and Methyltestosterone ... Esterified Estrogens and Methyltestosterone …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer.
Approved
Investigational
Matched Description: … An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer …
Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM). It is sold by Sanofi-Aventis under the brand name Adlyxin in the US and Lyxumia in the EU. Adlyxin recieved FDA approval July 28, 2016.
Approved
Matched Description: … It is sold by Sanofi-Aventis under the brand name Adlyxin in the US[L763] and Lyxumia in the EU. …
Matched Mixtures name: … LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) ... LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin glargine and lixisenatide …
Displaying drugs 251 - 275 of 14774 in total