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Displaying drugs 2726 - 2750 of 9511 in total
Measles virus vaccine live attenuated is a live virus vaccine for simultaneous vaccination against measles, which is a common childhood disease. The vaccine is prepared from the attenuated line of measles virus, derived from Enders' attenuated Edmonston strain and propagated in chick embryo cell culture.
Approved
Investigational
Matched Description: … The vaccine is prepared from the attenuated line of measles virus, derived from Enders' attenuated Edmonston …
Matched Mixtures name: … M-M-R II ... M-M-R II ... M-M-R II …
Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZeneca under the trade name Chirocaine. In particular, the specific levobupivacaine enantiomer is a worthwhile pursuit because it demonstrates less vasodilation and possesses a...
Approved
Investigational
Matched Description: … It is the S-enantiomer of bupivacaine. ... Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted ... When administered appropriately, the occurrence of adverse effects is not anticipated much if at all. …
Amaranthus tuberculatus pollen allergenic extract is used in allergenic testing.
Approved
Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris. It has a relatively narrow spectrum of activity that includes anaerobic bacteria as well as gram-positive cocci and bacilli and gram-negative bacilli. Interestingly,...
Approved
Vet approved
Matched Description: … Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious ... [L11593] It has a relatively narrow spectrum of activity that includes anaerobic bacteria as well as ... and has largely replaced, [lincomycin], a naturally occurring lincosamide and the eponymous member of
Matched Categories: … Antiinfectives for Treatment of Acne …
Matched Products: … EUROCLIN(R) V OVULOS ... ACNIBEN(R) 300 MG CAPSULA …
A commonly used x-ray contrast medium. As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Approved
Vet approved
Matched Categories: … Diagnostic Uses of Chemicals …
Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.
Approved
Matched Categories: … combinations of penicillins …
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p822)
Approved
Investigational
Withdrawn
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Categories: … combinations of sulfonamides …
A vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.
Approved
Investigational
Matched Description: … A vasodilator used in the treatment of angina pectoris. ... Its actions are similar to nitroglycerin but with a slower onset of action. …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Antibacterial, potentially toxic, and previously used to treat certain skin diseases. No longer prescribed.
Approved
Matched Categories: … combinations of sulfonamides …
Norelgestromin is a drug used in contraception. Norelgestromin is the active progestin responsible for the progestational activity that occurs in women after application of ORTHO EVRA patch.
Approved
Investigational
Matched Description: … active progestin responsible for the progestational activity that occurs in women after application of
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Chlortetracycline is a tetracycline antibiotic, and historically the first member of this class to be identified. It was discovered in 1945 by the scientist, Benjamin Minge Duggar, working at Lederle Laboratories under the supervision of Yellapragada Subbarow. He discovered that this antibiotic was the product of an actinomycete strain he...
Approved
Investigational
Vet approved
Matched Description: … Chlortetracycline is a _tetracycline_ antibiotic, and historically the first member of this class to ... 1945 by the scientist, Benjamin Minge Duggar, working at Lederle Laboratories under the supervision of ... He discovered that this antibiotic was the product of an actinomycete strain he cultured and obtained …
Matched Categories: … combinations of tetracyclines …
Eluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid receptor antagonist indicated for use in diarrhea-predominant irritable bowel syndrome (IBS-D). The mu-, kappa-, and delta-opioid receptors mediate endogenous and exogenous opioid response in the central nervous system and peripherally in the gastrointestinal system. Agonism of peripheral...
Approved
Investigational
Matched Description: … Agonism of peripheral mu-opioid receptors results in reduced colonic motility, while antagonism of central ... both pain and diarrhea characteristic of IBS-D. ... delta-opioid receptors results in improved analgesia, making eluxadoline usable for the symptoms of
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Lasmiditan is an oral medication used in the termination of migraine headaches that was first approved for use in the United States in October 2019.[L9338,L9356] It was also approved by the European Commission on August 17, 2022. Traditionally, the triptan class of anti-migraine medications (e.g. sumatriptan) have seen preferential use...
Approved
Investigational
Matched Description: … to terminate migraines through neuronal inhibition has resulted in the creation of a new class of anti-migraine ... [L43997] Traditionally, the triptan class of anti-migraine medications (e.g. ... Lasmiditan is an oral medication used in the termination of migraine headaches that was first approved …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Miconazole is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria as well. It is widely used to treat mucosal yeast infections, including both oral and vaginal infections; although intravenous miconazole is no longer available, a wide variety of suppositories, creams, gels, and tablet-based products are available.[L14021, L14024, L14027,...
Approved
Investigational
Vet approved
Matched Description: … oral and vaginal infections; although intravenous miconazole is no longer available, a wide variety of ... L14021, L14024, L14027, L14033, L14396] Miconazole is thought to act primarily through the inhibition of ... [A214523, L14021] It is currently available as a variety of prescription and over the counter products …
Matched Categories: … combinations of imidazole derivatives ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … MICATIN (R) 7 VAGINAL SUPPOSITORIES …
Desvenlafaxine (O-desmethylvenlafaxine) is the 0-demetyhlated active metabolite of venlafaxine. Like its parent drug, desvenlafaxine is also an antidepressant belonging to the class of serotonin-norepinephrine reuptake inhibitor (SNRI) class.[A261266,A261266] It was approved by the FDA in 2008 for the treatment of adults with major depressive disorder (MDD).[L6016,A261271] MDD is a highly...
Approved
Investigational
Matched Description: … Although the exact mechanism of pathophysiology is still unknown, imbalances or deficiencies of monoamines ... Desvenlafaxine (O-desmethylvenlafaxine) is the 0-demetyhlated active metabolite of [venlafaxine]. ... have been heavily implicated, thus the rationale behind the use of SNRI to treat MDD. …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of phenothiazine that was developed in France in 1946. Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.[A189907,A190153,A190159,A190150,A190171] Promethazine was granted FDA approval before 29...
Approved
Investigational
Matched Description: … [A189901] Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications ... ., is an N-dimethylaminopropyl derivative of [phenothiazine] that was developed in France in 1946. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Cyclic peptide antibiotic similar to viomycin. It is produced by Streptomyces capreolus.
Approved
Matched Categories: … Drugs for Treatment of Tuberculosis …
The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
Approved
Vet approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
Approved
Matched Description: … inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of
Matched Categories: … combinations of xanthines …
Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase II (CA-II) inhibitor indicated to reduce ocular pressure in patients with ocular hypertension or open-angle glaucoma. Although the exact pathophysiology of glaucoma is still unknown, one of the main hallmarks of this disease is vascular dysregulation and abnormalities.[A2049,A2051] The resulting vascular...
Approved
Matched Description: … [L35310] Although the exact pathophysiology of glaucoma is still unknown, one of the main hallmarks of ... success, systemic administration results in an increase in incidences of adverse effects. ... systemic anti-carbonic anhydrase (CA) therapy has been used for almost 50 years with varying degrees of
Matched Categories: … combinations of sulfonamides …
Oxtriphylline is the choline salt form of theophylline. Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Its main physiological reponse is to dilate the bronchioles. As such, oxytriphylline is indicated mainly for asthma, bronchospasm, and COPD (i.e. all...
Approved
Matched Description: … Oxtriphylline is the choline salt form of [theophylline]. ... It is marketed under the name Choledyl SA, and several forms of oxytriphylline have been discontinued …
Matched Categories: … combinations of xanthines …
A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.
Approved
Matched Description: … Danazol has been used in the treatment of endometriosis and some benign breast disorders. ... anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Ulipristal is a selective progesterone receptor modulator used for the purposes of emergency contraception (Ella) and for the treatment of uterine fibroids (Fibristal). It is a derivative of 19-norprogesterone and has both antagonistic and partial agonist activity at the progesterone receptor. It also binds to glucocorticoid receptor, however compared to...
Approved
Matched Description: … (Ella) and for the treatment of uterine fibroids (Fibristal). ... Ulipristal is a selective progesterone receptor modulator used for the purposes of emergency contraception ... It is a derivative of 19-norprogesterone and has both antagonistic and partial agonist activity at the …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
A synthetic progestational hormone with actions and uses similar to those of PROGESTERONE. It has been used in the treatment of functional uterine bleeding and endometriosis. As a contraceptive, it has usually been administered in combination with MESTRANOL.
Approved
Matched Description: … It has been used in the treatment of functional uterine bleeding and endometriosis. ... A synthetic progestational hormone with actions and uses similar to those of PROGESTERONE. …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Inclisiran is a long-acting, synthetic small interfering RNA (siRNA) directed against proprotein convertase subtilisin-kexin type 9 (PCSK9), which is a serine protease that regulates plasma low-density lipoprotein cholesterol (LDL-C) levels. By binding to PCSK9 messenger RNA, inclisiran prevents protein translation of PCSK9, leading to decreased concentrations of PCSK9 and plasma...
Approved
Investigational
Matched Description: … concentrations of PCSK9 and plasma concentrations of LDL cholesterol. ... risk of cardiovascular disease (CVD) and improving cardiovascular outcomes, as hypercholesterolemia ... By binding to PCSK9 messenger RNA, inclisiran prevents protein translation of PCSK9, leading to decreased …
Matched Categories: … Diagnostic Uses of Chemicals …
Displaying drugs 2726 - 2750 of 9511 in total