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Displaying drugs 2726 - 2750 of 9510 in total

Brinzolamide

Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase II (CA-II) inhibitor indicated to reduce ocular pressure in patients with ocular hypertension or open-angle glaucoma. Although the exact pathophysiology of glaucoma is still unknown, one of the main hallmarks of this disease is vascular dysregulation and abnormalities.[A2049,A2051] The resulting vascular...
Approved
Matched Description: … [L35310] Although the exact pathophysiology of glaucoma is still unknown, one of the main hallmarks of ... success, systemic administration results in an increase in incidences of adverse effects. ... systemic anti-carbonic anhydrase (CA) therapy has been used for almost 50 years with varying degrees of …
Matched Categories: … combinations of sulfonamides …

Oxtriphylline

Oxtriphylline is the choline salt form of theophylline. Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Its main physiological reponse is to dilate the bronchioles. As such, oxytriphylline is indicated mainly for asthma, bronchospasm, and COPD (i.e. all...
Approved
Matched Description: … Oxtriphylline is the choline salt form of [theophylline]. ... It is marketed under the name Choledyl SA, and several forms of oxytriphylline have been discontinued …
Matched Categories: … combinations of xanthines …

Danazol

A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.
Approved
Matched Description: … Danazol has been used in the treatment of endometriosis and some benign breast disorders. ... anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Ulipristal

Ulipristal is a selective progesterone receptor modulator used for the purposes of emergency contraception (Ella) and for the treatment of uterine fibroids (Fibristal). It is a derivative of 19-norprogesterone and has both antagonistic and partial agonist activity at the progesterone receptor. It also binds to glucocorticoid receptor, however compared to...
Approved
Matched Description: … (Ella) and for the treatment of uterine fibroids (Fibristal). ... Ulipristal is a selective progesterone receptor modulator used for the purposes of emergency contraception ... It is a derivative of 19-norprogesterone and has both antagonistic and partial agonist activity at the …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Norethynodrel

A synthetic progestational hormone with actions and uses similar to those of PROGESTERONE. It has been used in the treatment of functional uterine bleeding and endometriosis. As a contraceptive, it has usually been administered in combination with MESTRANOL.
Approved
Matched Description: … It has been used in the treatment of functional uterine bleeding and endometriosis. ... A synthetic progestational hormone with actions and uses similar to those of PROGESTERONE. …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Inclisiran

Inclisiran is a long-acting, synthetic small interfering RNA (siRNA) directed against proprotein convertase subtilisin-kexin type 9 (PCSK9), which is a serine protease that regulates plasma low-density lipoprotein cholesterol (LDL-C) levels. By binding to PCSK9 messenger RNA, inclisiran prevents protein translation of PCSK9, leading to decreased concentrations of PCSK9 and plasma...
Approved
Investigational
Matched Description: … concentrations of PCSK9 and plasma concentrations of LDL cholesterol. ... risk of cardiovascular disease (CVD) and improving cardiovascular outcomes, as hypercholesterolemia ... By binding to PCSK9 messenger RNA, inclisiran prevents protein translation of PCSK9, leading to decreased …
Matched Categories: … Diagnostic Uses of Chemicals …

Adenine

A purine base and a fundamental unit of adenine nucleotides.
Approved
Nutraceutical
Matched Description: … A purine base and a fundamental unit of adenine nucleotides. …
Matched Mixtures name: … IMUFLEX WB-RP Blood Bag System with Integral Whole Blood Leukocyte Reduction Filter (Removing Platelets …

Oxcarbazepine

Oxcarbazepine is an anti-epileptic medication used in the treatment of partial onset seizures that was first approved for use in the United States in 2000.[L8627,L8630,L8633] It is a structural derivative of carbamazepine and exerts a majority of its activity via a pharmacologically active metabolite, MHD, which exists as a racemate...
Approved
Matched Description: … [L8627,L8630,L8633] It is a structural derivative of [carbamazepine][A186101] and exerts a majority of ... Oxcarbazepine is an anti-epileptic medication used in the treatment of partial onset seizures that was ... via a pharmacologically active metabolite, MHD, which exists as a racemate in the blood - a pro-drug of …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …

Bendroflumethiazide

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
Approved
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. ... It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders …
Matched Categories: … combinations of sulfonamides …

Streptomycin

Streptomycin, an antibiotic derived from Streptomyces griseus, was the first aminoglycoside to be discovered and used in practice in the 1940s.[A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for their discovery of streptomycin and its antibacterial activity.[A233325,A232294] Although streptomycin was the first antibiotic...
Approved
Vet approved
Matched Description: … the first antibiotic determined to be effective against mycobacterium tuberculosis, it has fallen out of ... Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for their discovery of ... favor due to resistance and is now primarily used as adjunctive treatment in cases of multi-drug resistant …
Matched Categories: … Drugs for Treatment of Tuberculosis …

Zinc chloride

Zinc chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc levels and prevent deficiency syndromes. Zinc chloride was granted FDA approval before 26 June 1986.
Approved
Investigational
Matched Description: … Zinc chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Epinastine

Epinastine is used for the prevention of itching associated with allergic conjunctivitis. It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and H2-receptors to...
Approved
Investigational
Matched Description: … Epinastine is used for the prevention of itching associated with allergic conjunctivitis. ... the H1- and H2-receptors to stop itching and provide lasting protection, and 3. prevents the release of ... proinflammatory chemical mediators from the blood vessel to halt progression of the allergic response …
Matched Mixtures name: … FLURINOL(R) D COMPRIMIDOS DE LIBERACION MODIFICADA …

St. John's Wort

Approved
Investigational
Nutraceutical
Matched Mixtures name: … R. Formula …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Glucosamine

Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation. Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional benefits to nonsteroidal anti-inflammatory drugs treating the painful symptoms of OA. Glucosamine is commonly used over the counter as...
Approved
Investigational
Matched Description: … Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone ... may offer additional benefits to nonsteroidal anti-inflammatory drugs treating the painful symptoms of …
Matched Mixtures name: … ARTROFORT(R) COMPLEX …
Matched Products: … GLUCONITRIN(R) - S 1500 MG …

Hard fat

Approved
Matched Mixtures name: … Formulation R Hemorrhoidal Suppositories …

Dextrose, unspecified form

Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Vet approved
Matched Description: … Glucose is listed on the World Health Organization's List of Essential Medicines. ... Its aldohexose stereoisomer, dextrose or D-glucose, is the most commonly occurring isomer of glucose ... The unspecified form of glucose is commonly supplied as an injection for nutritional supplementation …
Matched Mixtures name: … Normosol-R and Dextrose ... Normosol-R and Dextrose ... Isolyte R In 5% Dextrose …

Levodopa

Levodopa is a prodrug of dopamine that is administered to patients with Parkinson's due to its ability to cross the blood-brain barrier[Label]. Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa to prevent...
Approved
Matched Description: … dopamine to treat symptoms of Parkinson's[Label]. ... Levodopa is a prodrug of dopamine that is administered to patients with Parkinson's due to its ability ... Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Isocarboxazid

Isocarboxazid has the formula 1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine-isocarboxazid. It is a monoamine oxidase inhibitor. It is used in the treatment of major depression, dysthymic disorder, atypical disorder, panic disorder and the phobic disorders. It was first introduced by Roche pharmaceuticals, further developed by Validus pharms Inc and first FDA approved as a prescription...
Approved
Matched Description: … [A31930] It is used in the treatment of major depression, dysthymic disorder, atypical disorder, panic …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Zimelidine

Zimelidine has been banned worldwide due to serious, sometimes fatal, cases of central and/or peripheral neuropathy known as Guillain-Barré syndrome and due to a peculiar hypersensitivity reaction involving many organs including skin exanthema, flu-like symptoms, arthralgias, and sometimes eosinophilia. Additionally, zimelidine was charged to cause an increase in suicidal ideation...
Approved
Withdrawn
Matched Description: … Zimelidine has been banned worldwide due to serious, sometimes fatal, cases of central and/or peripheral …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Ospemifene

Ospemifene is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. FDA approved on February 26, 2013.
Approved
Investigational
Matched Description: … moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. ... Ospemifene is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Oliceridine

Severe acute pain occurs through nociceptive signalling involving both ascending and descending spinal pathways, in which nerve conductance is mediated in part by the action of opioid receptors.[A218041, A218046] Opioid receptors are seven-transmembrane G-protein-coupled receptors (GPCRs), of which the μ-opioid receptor subtype is predominantly targeted by and is responsible for...
Approved
Investigational
Matched Description: … ascending and descending spinal pathways, in which nerve conductance is mediated in part by the action of ... [A218041, A218046] Opioid receptors are seven-transmembrane G-protein-coupled receptors (GPCRs), of which ... the μ-opioid receptor subtype is predominantly targeted by and is responsible for the effects of opioid …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Clotrimazole

This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the imidazole category of azole antifungals, possessing broad-spectrum antimycotic activity . It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As...
Approved
Vet approved
Matched Description: … As well as its antifungal activity, clotrimazole has become a drug of interest in treating several other ... widespread acceptance for the treatment of mycotic outbreaks such as vaginal yeast infections as well ... The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain …
Matched Mixtures name: … CLONODEX (R) …
Matched Categories: … combinations of imidazole derivatives …
Matched Products: … Fortinia OF …

Hydroxychloroquine

Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. Hydroxychloroquine is an aminoquinoline like chloroquine. It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus. Hydroxychloroquine is also used for the prophylaxis of malaria in...
Approved
Matched Description: … Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. ... [L8072] It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid ... [A183092] Chloroquine and hydroxychloroquine are both being investigated for the treatment of SARS-CoV …

Riboflavin

Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms …
Matched Mixtures name: … Harvest Of Values All B Complex Tab ... Herbs of Gold B Complex Plus Softgel …

Folic acid

Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis. More specifically, folic acid is required by the body for the synthesis of purines, pyrimidines, and methionine before incorporation into DNA...
Approved
Nutraceutical
Vet approved
Matched Description: … This results in a deficiency of coenzymes and a resultant buildup of toxic substances that are responsible ... , and erythropoiesis, and plays a protective factor in the development of cancer. ... Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential …
Matched Mixtures name: … Harvest Of Values All B Complex Tab ... Herbs of Gold B Complex Plus Softgel …
Displaying drugs 2726 - 2750 of 9510 in total