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Displaying drugs 2751 - 2775 of 9713 in total

AstraZeneca COVID-19 Vaccine

The AstraZeneca COVID-19 Vaccine (previously known as ChAdOx1 nCoV-19 or AZD1222) is one of several vaccines developed in 2020 for the prevention of COVID-19 caused by SARS-CoV-2.[L12669,L32649] The ChAdOx1 viral vector was developed at the University of Oxford and has been investigated as a potential vector for vaccines against another...
Approved
Investigational
Matched Description: … 18 and 55. ... adenovirus capable of producing the spike (S) protein of SARS-CoV-2, allowing for the formation of endogenous ... COVID-19 Vaccine due to signals of an increased risk of blood clots associated with thrombocytopenia …

Rabeprazole

Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Approved
Investigational
Matched Description: … Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. ... It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form ... Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal …
Matched Products: … Raberprazole Sodium D/r …

Sinecatechins

Sinecatechins is a botanical drug product for topical use. It is a partially purified fraction of the water extract of green tea leaves from Camellia sinensis, and is a mixture of catechins and other green tea components. Catechins constitute 85 to 95% (by weight) of the total drug substance which...
Approved
Investigational
Nutraceutical
Matched Description: … It is a partially purified fraction of the water extract of green tea leaves from Camellia sinensis, ... Catechins constitute 85 to 95% (by weight) of the total drug substance which includes more than 55% of ... and is a mixture of catechins and other green tea components. …

Ethylenediamine

Ethylenediamine is an organic compound that is used as a building block for the production of many other chemical products. It is also used as an excipient in many pharmacological preparations such as creams. Notably, ethylenediamine is a contact sensitizer capable of producing local and generalized reactions . Sensitivity to...
Approved
Experimental
Matched Description: … Ethylenediamine is an organic compound that is used as a building block for the production of many other ... Notably, ethylenediamine is a contact sensitizer capable of producing local and generalized reactions …

Poloxamer 188

Poloxamer 188 (P188) is a nonionic block linear copolymer that exhibits rheologic, anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models . Composed of two hydrophilic side-chains attached to a hydrophobic center core , its average molecular weight is 8400 Daltons. P188 was originally approved by the FDA in...
Approved
Investigational
Matched Description: … There is an evidence of P188 increasing the structural stability and resealing of the plasma membrane ... of _in vivo_ and _in vitro_ models [A27218]. ... The ability of P188 in attenuating membrane damage and cell injury has been demonstrated in a variety …

Rocuronium

Rocuronium (rapid onset-curonium) is a desacetoxy analogue of vecuronium with a more rapid onset of action. It is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Introduced in 1994, rocuronium has...
Approved
Matched Description: … Rocuronium (rapid onset-curonium) is a desacetoxy analogue of vecuronium with a more rapid onset of action ... Introduced in 1994, rocuronium has rapid onset, and intermediate duration of action. ... The drug is associated with the risk of developing allergic reactions in some high-risk patients, such …
Matched Products: … ROCUREX(R)100MG …

Obinutuzumab

Obinutuzumab is a humanized monoclonal antibody used as a combination treatment with chlorambucil to treat patients with untreated chronic lymphocytic leukemia. It was approved by the FDA in November 2013 and is marketed under the brand name Gazyva. There is a black box warning of fatal Hepatitis B Virus (HBV)...
Approved
Investigational
Matched Description: … There is a black box warning of fatal Hepatitis B Virus (HBV) reactivation and fatal Progressive Multifocal …
Matched Categories: … CD20 (Clusters of Differentiation 20) inhibitors …

Ioxilan

Ioxilan is a tri-iodinated diagnostic contrast agent. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs.
Approved
Matched Description: … Intravascular injection results in opacification of vessels in the path of flow of the contrast medium ... , permitting radiographic visualization of the internal structures of the human body until significant …
Matched Categories: … Diagnostic Uses of Chemicals …

Nitroglycerin

Nitroglycerin, also known as glyceryl trinitrate, is an organic nitrate and a vasodilating agent that was first discovered in 1847. Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced headaches in factory workers while workers with angina pectoris or heart failure experienced relief...
Approved
Investigational
Matched Description: … [A180172] Nitroglycerin is used in a variety of different conditions, including angina pectoris due …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Gliclazide

Gliclazide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It has been classified differently according to its drug properties in which based on its chemical structure, gliclazide is considered a first-generation sulfonylurea due to the structural presence of a sulfonamide group able to release...
Approved
Matched Description: … Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination ... the last 8-10 weeks of glucose control). ... β cells of the pancreas to release insulin. …
Matched Categories: … combinations of sulfonamides …

Interferon beta-1b

Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Approved

Loratadine

Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Approved
Investigational
Matched Description: … Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. ... [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation …
Matched Mixtures name: … LORAMINE R JARABE ... LORAMINE® R GRAGEAS ... DOSITAN (R) TABLETAS …
Matched Products: … LOTADAR(R) TABLETAS ... AIRET(R) TABLETAS 10 MG …

Mepivacaine

A local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
Approved
Vet approved
Matched Products: … Polocaine(r) -mpf (mepivacaine Hci) …

Meloxicam

Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve various types of pain, including pain caused by musculoskeletal conditions, osteoarthritis, and rheumatoid arthritis. With a longer half-life than most other NSAIDS, it is a favorable option for those who require once-daily dosing. Meloxicam is available in oral, transdermal, and...
Approved
Vet approved
Matched Description: … effects, however, this is a topic of controversy. ... Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve various types of pain, including ... It is a preferential COX-2 inhibitor, purportedly reducing the risk of adverse gastrointestinal tract …
Matched Products: … SINDULFAN (R) TABLETAS …

Dicloxacillin

One of the penicillins which is resistant to penicillinase.
Approved
Investigational
Vet approved
Matched Description: … One of the penicillins which is resistant to penicillinase. …
Matched Categories: … combinations of penicillins …

Cyclopenthiazide

Cyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients . It is a positive allosteric modulator at AMPA-A receptors .
Approved
Matched Categories: … combinations of sulfonamides …

Risdiplam

Risdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular atrophy (SMA). It increases systemic SMN protein concentrations by improving the efficiency of SMN2 gene transcription. This mechanism of action is similar to its predecessor nusinersen, the biggest difference being their route of administration: nusinersen...
Approved
Investigational
Matched Description: … [onasemnogene abeparvovec], whereas risdiplam offers the ease of oral bioavailability. ... Risdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular ... [L12615] It increases systemic SMN protein concentrations by improving the efficiency of _SMN2_ gene …
Matched Categories: … Survival of Motor Neuron 2 Splicing Modifier …

Tolevamer

Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.
Approved
Investigational
Matched Description: … It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …

Raltegravir

Raltegravir is an antiretroviral drug produced by Merck & Co., used to treat HIV infection. It received approval by the U.S. Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase inhibitors, to receive such approval.
Approved
Matched Description: … Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections …

Ranitidine

Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as cimetidine and famotidine. This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of its ability to decrease gastric acid secretion.[A176759,L10818] Ranitidine is often referred to as...
Approved
Withdrawn
Matched Description: … [L10818,F4253] The prevalence of GERD is thought to be 10-20% in western countries. ... This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of ... [A176843] Ranitidine has proven to be an effective treatment for relieving uncomfortable symptoms of …
Matched Products: … NEOCEPTIN R-150 TABLET 150 mg …

Desflurane

Desflurane, or I-653, a a volatile anesthetic that is more rapidly cleared and less metabolized than previous inhaled anesthetics such as methoxyflurane, sevoflurane, enflurane, or isoflurane.[A226390,A39015,A226893]. It was developed in the late 1980s out of a need for a more rapidly acting and rapidly cleared inhaled anesthetic.[A226883,A226888] Desflurane was granted...
Approved
Matched Description: … [A226883,A226888] Desflurane was granted FDA approval on 18 September 1992.[L30285] ... It was developed in the late 1980s out of a need for a more rapidly acting and rapidly cleared inhaled …

Propranolol

Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.
Approved
Investigational
Matched Description: … Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times ... [L6904] Propranolol is used to treat a number of conditions but most commonly is used for hypertension …

Sparfloxacin

Sparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. DNA gyrase is an essential enzyme which controls DNA topology and assists in DNA replication, repair, deactivation, and transcription.
Approved
Investigational
Withdrawn
Matched Categories: … Drugs for Treatment of Tuberculosis …

Polythiazide

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)
Approved
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Mixtures name: … Renese-R …
Matched Categories: … combinations of sulfonamides …

Risperidone

Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. It is one of the most widely used SGAs. Paliperidone, another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone). Schizophrenia and...
Approved
Investigational
Matched Description: … Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of ... [L12885] It is one of the most widely used SGAs. ... Risperidone is thought to reduce this overactivity through inhibition of dopaminergic D2 receptors and …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … ISPERIN(R)FAST 0.5 MG ... RISPERDAL CONSTA (R) 50 MG ... ISPERIN(R)FAST 2 MG TABLETA ORODISPERSABLE …
Displaying drugs 2751 - 2775 of 9713 in total