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Displaying drugs 2776 - 2800 of 9510 in total
Chronic angina is a common cardiovascular condition affecting millions worldwide and causes significant disability while interfering with daily activities. Ranolazine is a well-tolerated piperazine derivative used for the management of this condition, offering relief from uncomfortable and debilitating symptoms. With a mechanism of action different from drugs used to treat...
Approved
Investigational
Matched Description: … [A189234] Ranolazine is a well-tolerated piperazine derivative used for the management of this condition ... [L3580] With a mechanism of action different from drugs used to treat the same condition, ranolazine …
Clioquinol was withdrawn in 1983 due to neurotoxicity.
Approved
Vet approved
Withdrawn
Matched Mixtures name: … Aristoform R Crm 0.1% …
Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI). It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies.
Approved
Vet approved
Matched Description: … [A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Doxepin is a psychotropic agent with antidepressant and anxiolytic properties. It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer corresponding to cidoxepin. Doxepin commonly produces a 5:1 (E):(Z) racemic mixture. In a strict sense, doxepin is not a tricyclic antidepressant but...
Approved
Investigational
Matched Description: … [L5971] However, in 2010 it was approved for the treatment of insomnia. ... properties with members of the drug family including [amitriptyline], [clomipramine], [desipramine], ... is not a tricyclic antidepressant but it is commonly associated with the class since it shares a lot of
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Cetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms , . One of the most common uses for this drug is for a condition called allergic...
Approved
Matched Description: … One of the most common uses for this drug is for a condition called _allergic rhinitis_. ... Zyrtec_, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of ... The prevalence of allergic rhinitis in the United States is about 15% according to physician diagnoses …
Matched Products: … ZYRTEC-R ORAL SOLUTION 1 MG/ML ... ZYRTEC-R FILM-COATED TABLET 10 MG ... CERITAMIN (R) (CETIRIZINA)TABLETAS 10 MG …
Desogestrel, a prodrug, is a third generation progestogen and hence, a member of the gonane family which was largely used in Europe before being approved in the US and Canada. It was firstly generated from a study that showed that 11-beta and 11-alkylidene substituent in nortestosterone can enhance the biological...
Approved
Matched Description: … Desogestrel, a prodrug, is a third generation progestogen[A176315] and hence, a member of the gonane …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Hydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and...
Approved
Illicit
Matched Description: … carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and 8. ... Hydromorphone is a pure opioid,[A176468] a semi-synthetic hydrogenated ketone derivative of [morphine ... Structurally, hydromorphone derived from [morphine] in the modification of the hydroxyl group in the …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Levonorgestrel (LNG) is a synthetic progestogen similar to Progesterone used in contraception and hormone therapy.[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. Some of these devices...
Approved
Investigational
Matched Description: … Some of these devices are known as Jaydess, Kyleena, and Mirena. ... A subdermal implant of levonorgestrel that slowly releases the hormone over a long-term period is also ... [L7823] In addition to the above uses, levonorgestrel is used as a component of long-term combination …
Matched Mixtures name: … LILA(R) TABLETAS RECUBIERTAS …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first...
Approved
Investigational
Matched Description: … appear more than 24 hours after the first dose of a course of chemotherapy and is the only drug of its ... and treatment of chemotherapy-induced nausea and vomiting (CINV). ... As of 2008, it is the most recent 5-HT3 antagonist to enter clinical use. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
Approved
Investigational
Matched Description: … would otherwise promote narrowing of the blood vessels and lead to high blood pressure. ... Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that …
Matched Categories: … combinations of sulfonamides …
A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Approved
Investigational
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Pergolide is a long-acting dopamine agonist approved in 1982 for the treatment of Parkinson’s Disease. It is an ergot derivative that acts on the dopamine D2 and D3, alpha2- and alpha1-adrenergic, and 5-hydroxytryptamine (5-HT) receptors. It was indicated as adjunct therapy with levodopa/carbidopa in the symptomatic treatment of parkinsonian syndrome....
Approved
Investigational
Vet approved
Withdrawn
Matched Description: … It was later found that pergolide increased the risk of cardiac valvulopathy. ... Pergolide is a long-acting dopamine agonist approved in 1982 for the treatment of Parkinson’s Disease ... It was indicated as adjunct therapy with levodopa/carbidopa in the symptomatic treatment of parkinsonian …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis. It is often used topically in creams and eyedrops but is available in systemic formulations including tablets and injections.
Approved
Investigational
Matched Description: … An antibiotic isolated from the fermentation broth of Fusidium coccineum. …
Matched Mixtures name: … FUCICORT(R) …
Ribociclib is a selective cyclin-dependent kinase inhibitor, a class of drugs that help slow the progression of cancer by inhibiting two proteins called cyclin-dependent kinase 4 and 6 (CDK4/6). These proteins, when over-activated, can enable cancer cells to grow and divide too quickly. Targeting CDK4/6 with enhanced precision may play...
Approved
Investigational
Matched Description: … of cancer by inhibiting two proteins called cyclin-dependent kinase 4 and 6 (CDK4/6). ... Ribociclib is a selective cyclin-dependent kinase inhibitor, a class of drugs that help slow the progression …
Adrenergic beta-agonist used to control premature labor.
Approved
Investigational
An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease . Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical...
Approved
Matched Description: … issues regarding its lack of stability as a pharmaceutical agent [A174019]. ... treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of ... important research initiatives developed stable mesalazine formulations like the eudragit-S coating of
Matched Products: … Salofalk (r) 5-asa Suppositories - 250mg ... Salofalk (r) 5-asa Enteric Coated Tab- 250mg …
Rice allergenic extract is used in allergenic testing.
Approved
Famotidine is a competitive histamine-2 (H2) receptor antagonist that works to inhibit gastric acid secretion. It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. Compared to other H2 receptor antagonists, famotidine displays high selectivity towards...
Approved
Matched International brands: … Sedanium-R
Matched Description: … [L11166] While oral formulations of famotidine are more commonly used, the intravenous solution of the ... receptor antagonists, famotidine displays high selectivity towards this receptor; in a study consisting of
Matched Products: … เปปฟามิน (R) 20 …
An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.
Approved
Investigational
Matched Description: … An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza …
Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class,...
Approved
Investigational
Vet approved
Matched Description: … reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of ... drug was the first clinical useful drug in its class, and its approval was followed by the formulation of
Matched Products: … PRAZOGAS(R) INFUSION ... มีพราซิด(R) 40 มก. ชนิดฉีด …
Ritlecitinib (PF-06651600) is a highly selective inhibitor of Janus kinase 3 (JAK3) and the tyrosine kinase expressed in hepatocellular carcinoma (TEC) kinase family. In June 2023, it was approved by the FDA for the treatment of severe alopecia areata in adults and adolescents 12 years and older.[L47092,L47127] It was further...
Approved
Investigational
Matched Description: … of alopecia areata. ... [L48181] Ritlecitinib is administered orally and is the first member of its class. ... Ritlecitinib (PF-06651600) is a highly selective inhibitor of Janus kinase 3 (JAK3) and the tyrosine …
The conjugated estrogens are noncrystalline mixtures of purified female sex hormones obtained either by its isolation from the urine of pregnant mares or by synthetic generation from vegetal material. Both of these products are later conjugated to natrium sulfate by ester bonds in order to make them more water soluble.[L5605,...
Approved
Matched Description: … , 3% of equilenin sulfate, 5% of 17-alpha and 17-beta-dihydroequilenin sulfate, 2% of 17-alpha-estradiolsulfate ... and 3% of 17-beta-estradiolsulfate. ... represented by estrone sulfate followed by 25% of equilin sulfate, 15% of 17-alpha-dehydroequilenin sulfate …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
Approved
Investigational
Vet approved
Matched Description: … One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in …
Matched Categories: … combinations of sulfonamides …
Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. It is commonly known as quinalbarbitone in the United Kingdom.
Approved
Vet approved
Matched Categories: … combinations of barbiturates …
Displaying drugs 2776 - 2800 of 9510 in total