Displaying drugs 276 - 300 of 8810 in total
Difenoxin
Difenoxin is a 4-phenylpiperidine which is closely related to the opioid analgesic meperidine. Difenoxin alone is a USA Schedule I controlled drug, as it may be habit forming. However, it is listed as a Schedule IV controlled drug if combined with atropine, which is added to decrease deliberate misuse. Motofen(R)...
Approved
Illicit
Matched Synonyms: … 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotic acid …
Matched Iupac: … 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid …
Matched Description: … Difenoxin is a 4-phenylpiperidine which is closely related to the opioid analgesic meperidine. ... periphery and activates opioid receptors in the intestine rather than the central nervous system (CNS). [3] …
Matched Salts cas: … 35607-36-4 …
Matched Iupac: … 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid …
Matched Description: … Difenoxin is a 4-phenylpiperidine which is closely related to the opioid analgesic meperidine. ... periphery and activates opioid receptors in the intestine rather than the central nervous system (CNS). [3] …
Matched Salts cas: … 35607-36-4 …
Zafirlukast
Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once...
Approved
Investigational
Matched Synonyms: … 4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol-3-ylmethyl)-3-methoxy-N-o-tolylsulfonylbenzamide ... cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methylindole-5-carbamate …
Matched Iupac: … cyclopentyl N-[3-({2-methoxy-4-[(2-methylbenzenesulfonyl)carbamoyl]phenyl}methyl)-1-methyl-1H-indol-5 …
Matched Iupac: … cyclopentyl N-[3-({2-methoxy-4-[(2-methylbenzenesulfonyl)carbamoyl]phenyl}methyl)-1-methyl-1H-indol-5 …
Regadenoson
Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.
Approved
Investigational
Matched Iupac: … 1-{6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-9H-purin-2-yl}-N-methyl-1H-pyrazole ... -4-carboxamide …
Icodextrin
Icodextrin is an iso-osmotic peritoneal dialysis solution containing glucose polymers. It is used primarily for ambulatory peritoneal dialysis (CAPD) of diabetic patients and automated peritoneal dialysis (APD) for patients with end-stage renal disease. It is injected as a solution into the peritoneal cavity. The drug is absorbed via convective transport...
Approved
Investigational
Tapinarof
Tapinarof is a novel, first-in-class, small-molecule AhR agonist that is indicated for the treatment of adult psoriasis. It is available as a topical cream to be applied to the affected area once daily.[L41845, A248790] Tapiranof was first discovered as a metabolite (3,5-dihydroxy-4-isopropylstilbene) produced in Photorhabdus luminescens, a gram-negative bacillus that...
Approved
Investigational
Matched Synonyms: … 3,5-Dihydroxy-4-isopropyl-trans-stilbene …
Matched Description: … [L41845, A248790] Tapiranof was first discovered as a metabolite (3,5-dihydroxy-4-isopropylstilbene) ... [A248790] In 1959, it was noticed that _Heterorhabditis_ with a high amount of 3,5-dihydroxy-4-isopropylstilbene …
Matched Description: … [L41845, A248790] Tapiranof was first discovered as a metabolite (3,5-dihydroxy-4-isopropylstilbene) ... [A248790] In 1959, it was noticed that _Heterorhabditis_ with a high amount of 3,5-dihydroxy-4-isopropylstilbene …
Prednisone
A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver. Prednisone was granted FDA approval on 21 February 1955.
Approved
Vet approved
Nicergoline
An ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. It has been suggested to ameliorate cognitive deficits in cerebrovascular disease.
Approved
Investigational
Matched Synonyms: … (8β)-10-methoxy-1,6-dimethylergoline-8-methanol 5-bromo-3-pyridinecarboxylate (ester) …
Matched Iupac: … yl]methyl 5-bromopyridine-3-carboxylate ... 2-methoxy-6,11-dimethyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14-tetraen-4- …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Matched Iupac: … yl]methyl 5-bromopyridine-3-carboxylate ... 2-methoxy-6,11-dimethyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14-tetraen-4- …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Iothalamic acid
Iothalamic acid is an iodine containing organic anion used as a diagnostic contrast agent.
Approved
Matched Iupac: … 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid …
Matched Salts cas: … 1225-20-3 …
Matched Salts cas: … 1225-20-3 …
Sertindole
Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. Serdolect is developed by the Danish pharmaceutical company H. Lundbeck. It is a phenylindole derivative used in the treatment of schizophrenia. It was first marketed in 1996 in several European countries before being withdrawn two years later because of...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one …
Matched Iupac: … 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one …
Matched Products: … Serdolect 4 mg - Filmtabletten ... SERDOLECT 4 MG FILM KAPLI TABLET, 30 ADET …
Matched Iupac: … 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one …
Matched Products: … Serdolect 4 mg - Filmtabletten ... SERDOLECT 4 MG FILM KAPLI TABLET, 30 ADET …
Flunarizine
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
Approved
Matched Synonyms: … 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Iupac: … 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Salts cas: … 30484-77-6 …
Matched Iupac: … 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Salts cas: … 30484-77-6 …
Linezolid
Linezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. Its effects are bacteriostatic against both enterococci and staphylococci and bactericidal against most isolates of streptococci. Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein synthesis - more specifically,...
Approved
Investigational
Matched Synonyms: … N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide …
Matched Iupac: … N-{[(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide …
Matched Iupac: … N-{[(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide …
Migalastat
Fabry disease is a rare, progressive genetic disorder characterized by a defective GLA gene that causes a deficiency in the enzyme alpha-Galactosidase A (alpha-Gal A). This enzyme is responsible for breaking down glycosphingolipid substrate that, when deficient in patients with Fabry disease, builds up in the blood vessels, the kidneys,...
Approved
Investigational
Pralsetinib
Pralsetinib, similar to the previously approved selpercatinib, is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs) over other RTK classes.[A202055, A219751, L15986] Enhanced RET (Rearranged during transfection) oncogene expression is a hallmark of many cancers, including non-small cell lung cancer. Although multikinase inhibitors, including cabozantinib, ponatinib,...
Approved
Investigational
Matched Iupac: … (1s,4s)-N-[(1S)-1-[6-(4-fluoro-1H-pyrazol-1-yl)pyridin-3-yl]ethyl]-1-methoxy-4-{4-methyl-6-[(5-methyl ... -1H-pyrazol-3-yl)amino]pyrimidin-2-yl}cyclohexane-1-carboxamide …
Matched Description: … ARROW (NCT03037385) is still ongoing, pralsetinib was granted accelerated FDA approval on September 4, …
Matched Description: … ARROW (NCT03037385) is still ongoing, pralsetinib was granted accelerated FDA approval on September 4, …
Haloperidol
Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide. While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain, it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor (mainly D2), particularly within...
Approved
Matched Synonyms: … 1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine ... 4'-fluoro-4-(4-hydroxy-4-(4'-chlorophenyl)piperidino)butyrophenone ... 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-one …
Matched Iupac: … 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one …
Matched Salts cas: … 53515-91-6 …
Matched Products: … HALOPERIDOL-NEURAX 4 MG ... Haldol Decanoat 150 mg/3 ml Injektionslösung ... NORODOL DEKANOAT 150 MG/3 ML IM ENJ. ICIN COZELTI, 1 AMPUL …
Matched Iupac: … 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one …
Matched Salts cas: … 53515-91-6 …
Matched Products: … HALOPERIDOL-NEURAX 4 MG ... Haldol Decanoat 150 mg/3 ml Injektionslösung ... NORODOL DEKANOAT 150 MG/3 ML IM ENJ. ICIN COZELTI, 1 AMPUL …
Magnesium hydroxide
Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form.
Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used commercially...
Approved
Investigational
Matched Mixtures name: … NOAX 3 ... HIDROXDO DE ALUMINIO 4% + HIDROXDO DE MAGNESIO 4% + SIMETICONA 0.4% SUSPENSION ... HIDROXIDO DE ALUMINIO 4% + HIDROXIDO DE MAGNESIO 4% + SIMETICONA 0.4% SUSPENSION …
Topiramate
Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.[A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with phentermine for chronic weight management therapy...
Approved
Matched Iupac: … [(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl sulfamate …
Matched Salts cas: … 1246279-00-4 …
Matched Salts cas: … 1246279-00-4 …
Dutasteride
Dutasteride is an oral synthetic 4-azasteroid commonly marketed under the trade name Avodart. It is a novel dual 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and irreversible manner. Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary hormonal...
Approved
Investigational
Matched Synonyms: … (5α,17β)-N-(2,5-bis(trifluoromethyl)phenyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide ... α,α,α,α',α',α'-hexafluoro-3-oxo-4-aza-5α-androst-1-ene-17β-carboxy-2',5'-xylidide …
Matched Description: … Dutasteride is an oral synthetic 4-azasteroid commonly marketed under the trade name Avodart. …
Matched Description: … Dutasteride is an oral synthetic 4-azasteroid commonly marketed under the trade name Avodart. …
Niacin
Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.[L7550,L7553,L7556,L7559,L7562,L7565]
Approved
Investigational
Nutraceutical
Matched Synonyms: … 3-carboxypyridine ... 3-Pyridinecarboxylic acid ... 3-Pyridylcarboxylic acid …
Matched Iupac: … pyridine-3-carboxylic acid …
Matched Mixtures name: … B 6 Plus ... Irospan 24/6 ... Irospan 24/6 …
Matched Products: … B-3 500mg Continuous Released …
Matched Iupac: … pyridine-3-carboxylic acid …
Matched Mixtures name: … B 6 Plus ... Irospan 24/6 ... Irospan 24/6 …
Matched Products: … B-3 500mg Continuous Released …
Citalopram
Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.[A261316,A14720] Citalopram enhances serotonergic transmission through the...
Approved
Matched Iupac: … 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile …
Baricitinib
Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthritis. By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune responses. Baricitinib was...
Approved
Investigational
Matched Iupac: … 2-[1-(ethanesulfonyl)-3-(4-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1H-pyrazol-1-yl)azetidin-3-yl]acetonitrile …
Matched Products: … โอลูเมียนท์ (4 มก.) ... UNAMİTY 4 MG FİLM KAPLI TABLET, 7 ADET ... UNAMİTY 4 MG FİLM KAPLI TABLET, 14 ADET …
Matched Products: … โอลูเมียนท์ (4 มก.) ... UNAMİTY 4 MG FİLM KAPLI TABLET, 7 ADET ... UNAMİTY 4 MG FİLM KAPLI TABLET, 14 ADET …
Phylloquinone
Vitamin K1, also called phylloquinone or phytonadione, is a fat soluble vitamin.[L33319,L33345] Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates precursors to coagulation factors II, VII, IX, and X.[A234264,A234195,A234259] It is indicated in the treatment of coagulation disorders due to faulty formation of coagulation factors II,...
Approved
Investigational
Matched Synonyms: … 3-Phytylmenadione ... 2-Methyl-3-phytyl-1,4-naphthochinon ... 2-Methyl-3-phytyl-1,4-naphthoquinone …
Matched Iupac: … 2-methyl-3-[(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-yl]-1,4-dihydronaphthalene-1,4-dione …
Matched Mixtures name: … Omega-3 Rx Complete ... Mvc 9+4 Inj …
Matched Iupac: … 2-methyl-3-[(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-yl]-1,4-dihydronaphthalene-1,4-dione …
Matched Mixtures name: … Omega-3 Rx Complete ... Mvc 9+4 Inj …
Technetium Tc-99m tetrofosmin
Technetium Tc-99m tetrofosmin is a drug used in nuclear myocardial perfusion imaging. The radioisotope, technetium-99m, is chelated by two 1,2-bis[di-(2-ethoxyethyl)phosphino]ethane ligands which belong to the group of diphosphines and which are referred to as tetrofosmin. It is a lipophilic technetium phosphine dioxo cation that was formulated into a freeze-dried kit...
Approved
Amiloxate
Amiloxate is an EMA-approved chemical UV-filter found in over-the-counter sunscreen products at concentrations up to 10%m . It is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity .
Approved
Matched Synonyms: … 3-(4-Methoxyphenyl)-2-propenoic acid, 3-methylbutyl ester …
Matched Iupac: … 3-methylbutyl (2E)-3-(4-methoxyphenyl)prop-2-enoate …
Matched Description: … It is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. …
Matched Iupac: … 3-methylbutyl (2E)-3-(4-methoxyphenyl)prop-2-enoate …
Matched Description: … It is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. …
Famciclovir
Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections. It is most commonly used to treat herpes zoster (shingles). Famciclovir is a prodrug of penciclovir with higher oral bioavailability.
Approved
Investigational
Matched Synonyms: … 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine ... acetic acid 2-acetoxymethyl-4-(2-amino-purin-9-yl)-butyl ester …
Matched Iupac: … 2-[(acetyloxy)methyl]-4-(2-amino-9H-purin-9-yl)butyl acetate …
Matched Iupac: … 2-[(acetyloxy)methyl]-4-(2-amino-9H-purin-9-yl)butyl acetate …
Isoniazid
Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Approved
Investigational
Matched Synonyms: … 4-pyridinecarbohydrazide ... Pyridine-4-carboxylic acid hydrazide …
Matched Iupac: … pyridine-4-carbohydrazide …
Matched Mixtures name: … TB VIT 6 ... PRO TB 3 KID ... ริมสตาร์ 4 - FDC …
Matched Iupac: … pyridine-4-carbohydrazide …
Matched Mixtures name: … TB VIT 6 ... PRO TB 3 KID ... ริมสตาร์ 4 - FDC …
Displaying drugs 276 - 300 of 8810 in total