Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 276 - 300 of 14564 in total

1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol))

Palmitoyloleoyl-phosphatidylglycerol was a component of Surfaxin, discontinued in 2017, which acted as a surfactant [FDA Label]. The product was meant to compensate for alveolar surfactant deficiency and reduce to likelihood of alveolar collapse leading to acute respiratory collapse.
Approved
Experimental
Matched Synonyms: … 1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)) ... PG(16:0/18:1) ... PG(16:0/18:1(9Z)) …
Matched Name: … 1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)) …
Matched Description: … Palmitoyloleoyl-phosphatidylglycerol was a component of Surfaxin, discontinued in 2017, which acted as ... The product was meant to compensate for alveolar surfactant deficiency and reduce to likelihood of alveolar ... a surfactant [FDA Label]. …
Matched Salts name: … 1-palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)), sodium salt …

Lovotibeglogene autotemcel

Lovotibeglogene autotemcel consists of autologous hematopoietic stem and progenitor cells transduced with the BB305 lentiviral vector encoding a modified β-globin gene. Specifically, lovotibeglogene autotemcel provides a functional copy of a modified beta-globin gene (βA-T87Q-globin) that when combined with α-globin, produces hemoglobins with similar oxygen-binding capacity as wild type hemoglobin. Additionally,...
Approved
Investigational
Matched Description: … two treatments comprising the first cell-based gene therapies for the treatment of SCD in patients 12 ... Specifically, lovotibeglogene autotemcel provides a functional copy of a modified beta-globin gene (β ... with the BB305 lentiviral vector encoding a modified β-globin gene. …
Matched Categories: … Autologous Hematopoietic Stem Cell-Based Gene Therapy …

Ibrexafungerp

Ibrexafungerp, also known as SCY-078 or MK-3118, is a novel enfumafungin derivative oral triterpene antifungal approved for the treatment of vulvovaginal candidiasis (VVC), also known as a vaginal yeast infection.[A235384,L34349] It was developed out of a need to treat fungal infections that may have become resistant to echinocandins or azole...
Approved
Investigational
Matched Synonyms: … TRIMETHYLBUTOXY)-1,6A,8,10A-TETRAMETHYL-8- ((2R)-3-METHYLBUTAN-2-YL)-14-(5-(PYRIDIN-4-YL)-1H-1,2,4- TRIAZOL-1- …
Matched Iupac: … trimethylbutoxy]-5,7,10,15-tetramethyl-7-[(2R)-3-methylbutan-2-yl]-20-[5-(pyridin-4-yl)-1H-1,2,4-triazol-1- …
Matched Description: … is not present in humans, limiting the chance of renal or hepatic toxicity. ... approved for the treatment of vulvovaginal candidiasis (VVC), also known as a vaginal yeast infection ... [A235384,L34349] It was developed out of a need to treat fungal infections that may have become resistant …

Pemigatinib

Pemigatinib is a small molecule kinase inhibitor with antitumour activity. It works by inhibiting fibroblast growth factor receptors (FGFRs), which are receptor tyrosine kinases that activate signalling pathways in tumour cells. FGFRs gained attention as potential therapeutic targets in selected cancers, as FGFR gene alterations were observed in a wide...
Approved
Investigational
Matched Description: … were observed in a wide variety of cancers including those of the urinary bladder, breast, ovary, prostate ... exhibited gene rearrangements resulting in oncogenic fibroblast growth factor 2 (FGFR2) fusion proteins ... [A193716] In April 2020, pemigatinib was approved by the FDA for the treatment of unresectable locally …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring ... Receptor, Fibroblast Growth Factor, Type 1, antagonists & inhibitors …

Alpelisib

Alpelisib is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potent antitumor activity. It works by selectively inhibiting class I PI3K p110α , which is the catalytic subunit of PI3K, a lipid kinase that plays a role in various biological processes, including proliferation, survival, differentiation, and metabolism. Alpelisib was designed to target...
Approved
Investigational
Matched Description: … Alpelisib was designed to target this enzyme that appears to be mutated at a rate of nearly 30% in human ... To initiate alpelisib therapy, it is required that the presence of a PIK3CA mutation in the tissue and ... [L6652] In April 2022, the FDA granted the use of alpelisib in the treatment of PIK3CA-Related Overgrowth …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …

Influenza B virus B/Wisconsin/1/2010 live (attenuated) antigen

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Synonyms: … Influenza B Virus B/wisconsin/1/2010 Live(attenuated) Antigen …
Matched Name: … Influenza B virus B/Wisconsin/1/2010 live (attenuated) antigen …
Matched Description: … Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the ... A seasonally-specific component of the influenza vaccine. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …

Daclatasvir

Daclatasvir is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment of chronic HCV genotype 1 and 3 infection. It is marketed under the name DAKLINZA and is contained in daily oral tablets as the hydrochloride salt form . Hepatitis C is an infectious liver disease...
Approved
Investigational
Matched Iupac: … methyl N-[(2S)-1-[(2S)-2-[5-(4'-{2-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl]pyrrolidin ... -2-yl]-1H-imidazol-5-yl}-[1,1'-biphenyl]-4-yl)-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan- …
Matched Description: … a nonstructural phosphoprotein encoded by HCV. ... of chronic HCV genotype 1 and 3 infection. ... of new HCV replication complexes by modulating the NS5A phosphorylation status [A19640]. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Antivirals for treatment of HCV infections …

Cisplatin

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.
Approved
Matched Description: … It was the first member of its class, which now also includes carboplatin and oxaliplatin. ... Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug ... used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer …
Matched Categories: … Compounds used in a research, industrial, or household setting ... OCT2 Substrates with a Narrow Therapeutic Index ... Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Matched Products: … CISPLATIN CS 50MG IN 50ML INJ ... CISPLATINO 10 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... KEMOPLAT 1 MG/ML …

Albutrepenonacog alfa

Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human albumin (rAlbumin). It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. It was also approved by FDA and EMA in 2016. It...
Approved
Matched Description: … It is currently marketed in the forms of 250, 500, 1000 and 2000 IU/vial.[L2305] ... It was also approved by FDA and EMA in 2016. ... Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation …

Coal tar

Coal tar is a brown or black liquid of extremely high viscosity. Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas. Coal tars are complex and variable mixtures of phenols, polycyclic aromatic hydrocarbons (PAHs), and heterocyclic compounds. It has been...
Approved
Matched Description: … Coal tar is a brown or black liquid of extremely high viscosity. ... Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas. ... It has been indicated for local relief of itching, dryness, and irritation caused by psoriasis, seborrhea …
Matched Mixtures name: … Multi-action Denorex 2-IN-1 Dandruff Shampoo + Conditioner …
Matched Products: … Exorex Gel 1 ... Exorex Formula 1% ... Tersa-tar Mild Shp 1% …

Lorlatinib

Lorlatinib is a third-generation ALK tyrosine kinase inhibitor (TKI) for patients with ALK-positive metastatic non-small cell lung cancer which was first approved by the US FDA in November of 2018. It was subsequently approved by the EMA in 2019 for the treatment of select patients with previously treated advanced ALK-positive...
Approved
Investigational
Matched Iupac: … 13-fluoro-4,8,16-trimethyl-9-oxo-17-oxa-4,5,8,20-tetraazatetracyclo[16.3.1.0^{2,6}.0^{10,15}]docosa-1( …
Matched Description: … It was subsequently approved by the EMA in 2019 for the treatment of select patients with previously ... non-small cell lung cancer[L39905] which was first approved by the US FDA in November of 2018. ... include lorlatinib as a first-line treatment option in advanced ALK-positive NSCLC. …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring ... Organic Cation Transporter 1 Inhibitors …

Vecuronium

Monoquaternary homolog of pancuronium. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other...
Approved
Investigational
Matched Iupac: … -1H-cyclopenta[a]phenanthren-2-yl]-1-methylpiperidin-1-ium ... 1-[(1R,2S,3aS,3bR,5aS,7S,8S,9aS,9bS,11aS)-1,7-bis(acetyloxy)-9a,11a-dimethyl-8-(piperidin-1-yl)-hexadecahydro …
Matched Description: … A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. ... Monoquaternary homolog of pancuronium. ... Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination …
Matched Products: … BROCURIX 10 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... BROMURO DE VECURONIO 4 MG/VIAL POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 FLAKON VE 1 AMPUL …

Orciprenaline

A beta-adrenergic agonist used in the treatment of asthma and bronchospasms. [PubChem]
Approved
Matched Iupac: … 5-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,3-diol …
Matched Description: … A beta-adrenergic agonist used in the treatment of asthma and bronchospasms. [PubChem] …

Gadoteridol

Gadoteridol is a macrocyclic nonionic gadolinium that provides contrast enhancement of the brain, spine, and surrounding tissues, resulting in improved visualization (compared with unenhanced MRI) of lesions with abnormal vascularity or those thought to disrupt the normal blood-brain barrier.[A263076,A263081,L49871] It was 1 of the 3 macrocyclic gadolinium-based contrast agents (GBCAs)...
Approved
Investigational
Matched Iupac: … gadolinium(3+) 2-[4,7-bis(carboxylatomethyl)-10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecan-1-yl] …
Matched Description: … Gadoteridol is a macrocyclic nonionic gadolinium that provides contrast enhancement of the brain, spine ... , and surrounding tissues, resulting in improved visualization (compared with unenhanced MRI) of lesions ... [A263076,A263081,L49871] It was 1 of the 3 macrocyclic gadolinium-based contrast agents (GBCAs) that …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Diagnostic Uses of Chemicals …

Inosine pranobex

Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, and dimethylaminoisopropanol used as an antiviral drug.
Approved
Matched Synonyms: … Inosine-2-hydroxypropyldimethylammonium 4-acetamidobenzoate (1:3) …
Matched Iupac: … tris((2R)-1-(dimethylamino)propan-2-ol); tris(4-acetamidobenzoic acid); 9-[(2R,3R,4S,5R)-3,4-dihydroxy …
Matched Description: … Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, …

Potassium nitrate

Potassium nitrate is an inorganic salt with a chemical formula of KNO3. It is a natural source of nitrate and has been used as a constituent for several different purposes, including food preservatives, fertilizers, tree stump removal, rocket propellants, and fireworks. Potassium nitrate is a common active ingredient in toothpaste,...
Approved
Matched Description: … It provides increasing protection against painful sensitivity of the teeth to cold, heat, acids, sweets ... In addition, potassium nitrate is used as a diuretic in pigs, cattle, and horses. ... It is a natural source of nitrate and has been used as a constituent for several different purposes, …
Matched Mixtures name: … Made By Dentists, Inc. Rebuilding ... The Duo ... The Duo …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Amlodipine

Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched Description: … Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the ... Amlodipine is commonly used in the treatment of high blood pressure and angina. ... associated with a lower incidence of myocardial depression and cardiac conduction abnormalities than …
Matched Mixtures name: … VARTERAL NF® 320 MG / 5 MG ... VARTERAL NF® 320 MG / 5 MG ... VARTERAL HCT NF® 160/10/12.5 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … PRESONE-1 ... A-B VASK 5 ... A-B VASK 10 …

Meningococcal polysaccharide vaccine group C

Meningococcal group C polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup C. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup C.
Approved
Experimental
Investigational
Matched Description: … caused by the serogroup C. ... *N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia ... It is subcutaneously administered as an active immunization against the invasive meningococcal disease …
Matched Mixtures name: … Menjugate 10 Mikrogramm Injektionssuspension in einer Fertigspritze ... Menomune-A/c/y/w-135 ... Menomune-A/c/y/w-135 …

Elacestrant

Elacestrant is a non-steroidal small molecule and an estrogen receptor (ER) antagonist.[A256838,L44918] In January 2023, it was approved by the FDA for the treatment of ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer.[L44918,L44948] It received a similar approval in the EU in September 2023. Elacestrant binds to estrogen receptor-alpha (ERα)...
Approved
Investigational
Matched Description: … [A256838,L44918] In January 2023, it was approved by the FDA for the treatment of ER-positive, HER2-negative ... [L44918,L44948] It received a similar approval in the EU in September 2023. ... a SERD represents a therapeutic approach for the treatment of endocrine-resistant breast cancers. …

Alclometasone

Alclometasone is synthetic glucocorticoid steroid for topical use in dermatology as anti-inflammatory, antipruritic, antiallergic, antiproliferative and vasoconstrictive agent.
Approved
Matched Iupac: … ,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one ... (1R,2R,3aS,3bS,4R,9aR,9bS,10S,11aS)-4-chloro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H …
Matched Description: … Alclometasone is synthetic glucocorticoid steroid for topical use in dermatology as anti-inflammatory …

Duvelisib

Duvelisib, also known as IPI-145 and INK-1197, is a small-molecule inhibitor of phosphoinositide-3 kinases that was designed initially to prove that simultaneous inhibition of the isoforms delta and gamma can produce a broad adaptative and innate immune cell inhibitory activity. All the work around duvelisib showed that this agent is...
Approved
Investigational
Matched Iupac: … 8-chloro-2-phenyl-3-[(1S)-1-[(9H-purin-6-yl)amino]ethyl]-1,2-dihydroisoquinolin-1-one …
Matched Description: … All the work around duvelisib showed that this agent is a potent inhibitor of both forms. ... that was designed initially to prove that simultaneous inhibition of the isoforms delta and gamma can ... Duvelisib, also known as IPI-145 and INK-1197, is a small-molecule inhibitor of phosphoinositide-3 kinases …

Iofetamine I-123

Approved
Matched Iupac: … {1-[4-(¹²³I)iodophenyl]propan-2-yl}(propan-2-yl)amine …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Diagnostic Uses of Chemicals ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Ciltacabtagene autoleucel

Multiple myeloma is a malignancy involving the plasma cells of the bone marrow. It is a rare malignancy, with an estimated yearly incidence of 6.5 people per 100,000, and is variable in its presentation - some patients may remain entirely asymptomatic, while others may experience a range of symptoms including...
Approved
Investigational
Matched Description: … [A245854] Carvykti was first approved by the FDA in February 2022 for the treatment of relapsed or refractory ... Multiple myeloma is a malignancy involving the plasma cells of the bone marrow. ... choice target in the development of immunotherapies against multiple myeloma. …
Matched Categories: … Antineoplastic cell and gene therapy …

Lipoic acid

A vitamin-like antioxidant.
Approved
Investigational
Nutraceutical
Matched Description: … A vitamin-like antioxidant. …
Matched Mixtures name: … BENEDAY 250/250/1/300 MG 50 ENTERIK KAPLI TABLET ... TIOPATI-B 600 MG/250 MG/1 MG FILM TABLET, 30 ADET ... TIOPATI-B 600 MG/250 MG/1 MG FILM TABLET, 90 ADET …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … A-LIPOR® ... NUTRABIOTICS A-LIPOR ® ACIDO ALFA LIPOICO ... A-LIPOR P.O® 600 MG TABLETAS RECUBIERTAS …

Nitrogen

Nitrogen is a chemical element with symbol N and atomic number 7. At room temperature, it is a transparent, odorless diatomic gas. Liquid nitrogen is used principally in cryotherapy for removal of diseased skin. Liquid nitrogen helps in removal of skin lesions through necrosis, which results from the freezing and...
Approved
Vet approved
Matched Description: … Liquid nitrogen helps in removal of skin lesions through necrosis, which results from the freezing and ... Liquid nitrogen is used principally in cryotherapy for removal of diseased skin. ... thawing of cells. …
Matched Mixtures name: … Oxygen USP, Nitrogen Nf, Medical Gas Mixture …
Matched Products: … N/A ... Nitrogen Nf ... Liquid Nitrogen Nf …
Displaying drugs 276 - 300 of 14564 in total