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Displaying drugs 301 - 325 of 5910 in total
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … (74-SERINE (C>S),245-THREONINE (A>T))BOS TAURUS ADENOSINE DEAMINASE (BOVINE ADENOSINE AMINOHYDROLASE, ... ON N.ALPHA..1ALANINE AND N6 OF LYSINE RESIDUES WITH ... COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND ON N6 OF LYSYL RESIDUES (K) WITH AN …
Matched Description: … in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group ... in alanine and lysine residues. ... [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Antineoplastic and Immunomodulating Agents ... Adenosine Deaminase Inhibitors ... Recombinant Adenosine Deaminases …
Investigational
Matched Synonyms: … antibody-drug conjugate comprised of a human aglycosylated anti-CD74 IgG1 antibody (SP7219) and two non-cleavable …
PRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface.
Investigational
Matched Synonyms: … genetically modified using a non-viral system to express a CD33 CAR, membrane bound Interleukin-15, and
Matched Description: … genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and
Investigational
Matched Synonyms: … CYCLIZED P12 (PEPTIDE BOND BETWEEN THE CARBOXY AND AMINO-TERMINAL ENDS OF THE LINEAR PEPTIDE PSHISKYILRWRPK ... PROLYL-L-SERYL-L-HISTIDYL-L-ISOLEUCYL-L-SERYL-L-LYSYL-L-TYROSYL-L-ISOLEUCYL-L-LEUCYL- L-ARGINYL-L-TRYPTOPHANYL-L-ARGINYL-L-PROLYL-L-LYSYL …
Matched Iupac: … N-{3-[(3S,6S,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S,42S,45S)-3,30-bis(4-aminobutyl)-24,36-bis[(2S)-butan ... -2-yl]-18-(3-carbamimidamidopropyl)-33,42-bis(hydroxymethyl)-27-[(4-hydroxyphenyl)methyl]-39-[(1H-imidazol ... -4-yl)methyl]-15-[(1H-indol-3-yl)methyl]-21-(2-methylpropyl)-2,5,11,14,17,20,23,26,29,32,35,38,41,44- …
Experimental
Matched Synonyms: … Strychnos nux-vomica ... Nux vomica seed ... Nux vomica extract …
Matched Name: … Nux vomica extract …
Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid. It is a topical analgesic used for temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and bruises. Unlike other topical analgesics, trolamine...
Approved
Matched Iupac: … 2-[bis(2-hydroxyethyl)amino]ethan-1-ol; 2-hydroxybenzoic acid
Matched Description: … It also displays low systemic absorption upon dermal or topical administration [A32190] and has low skin ... Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid ... temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids
Matched Products: … Up and Up Pain Relief Odorless ... Up and Up Odor-free Pain Relieving Cream ... Blue-Emu Ultra with Hemp Seed
Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration. Menthol mediates anesthetic properties and...
Approved
Matched Synonyms: … L-menthol ... (−)-(1R,3R,4S)-menthol ... (1R,3R,4S)-(−)-menthol …
Matched Description: … Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. ( ... -)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration ... Menthol mediates anesthetic properties and anti-irritating properties locally, thus it is widely used …
Matched Mixtures name: … Orajel 3X Medicated For Toothache and Gum ... Zilactin-lip (regular and Cherry Flavour) ... ยาแก้ปวดฟัน พาตาร์ 75 (ตราปืน เอ็ม 16) …
Matched Categories: … Antipruritics and Local Anesthetics ... Basic Lotions and Liniments ... Herbs and Natural Products ... Other Cold and Cough Preparations …
Matched Products: … Musle and Joint ... Performance and Recovery ... BIOFREEZE PAIN RELIEVING GEL 3.5%W/W …
Verpasep caltespen is a recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from Mycobacterium bovis, and the human papilloma viral (HPV) protein E7. Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be used to design vaccines against a...
Investigational
Matched Synonyms: … Recombinant fusion protein of Mycobacterium bovis BCG Hsp65 and HPV16 E7 ... Heat-shock protein HSP 65 (Mycobacterium BCG) fusion protein with transcription factor E7 (human papillomavirus …
Matched Description: … _Mycobacterium bovis_, and the human papilloma viral (HPV) protein E7. ... E7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen ... Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be …
evorpacept is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)).
Investigational
Matched Synonyms: … protein alpha (SIRPalpha) variant 1 (v1) genetically linked to a modified and inactive Fc domain of ... A CD47-binding, fusion protein containing a high affinity engineered D1 domain of human signal regulatory …
Matched Description: … is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
Pacmilimab is under investigation in clinical trial NCT04596150 (Study to Evaluate the Safety and Antitumor Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer).
Investigational
Matched Synonyms: … (SYNTHETIC MASKING MOIETY AND CLEAVABLE MOIETY PROTEASE SUBSTRATE-CONTAINING) FUSION PROTEIN WITH HUMAN ... Protease-activated anti-pd-l1 antibody prodrug cx-072 ... PROGRAMMED CELL DEATH-LIGAND 1) (HUMAN MONOCLONAL CX-072 .GAMMA.4-CHAIN), DISULFIDE WITH PRODOMAIN PROTEIN
Matched Description: … Pacmilimab is under investigation in clinical trial NCT04596150 (Study to Evaluate the Safety and Antitumor ... Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer). …
Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms. It is selective for the H1 receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier - this is in contrast to previous first-generation antihistamines, such as diphenhydramine, which readily bind to off-targets...
Approved
Investigational
Matched Synonyms: … Terfenadine acid metabolite ... 4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acid
Matched Iupac: … 2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid
Matched Description: … L4269] It is selective for the H1 receptor, carries little-to-no activity at off-targets, and ... [A1452] Fexofenadine is the major active metabolite of [terfenadine][A1495] and is administered as a …
Matched Mixtures name: … FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE ... FEXOFENADINE HCl AND PSEUDOEPHEDRINE HCl ... FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy Relief ... Up and Up Non Drowsy Allergy Relief …
Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole. It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) along with other pathologies...
Approved
Investigational
Matched Iupac: … 2-{[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfinyl}-1H-1,3-benzodiazole …
Matched Description: … [A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective ... Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally ... at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) along …
Matched Mixtures name: … HELIPAK 500 + 30 + 1000mg TEDAVİ PAKETİ, 7 TABLET ... Lansoprazole, Amoxicillin, and Clarithromycin ... Lansoprazole, Amoxicillin and Clarithromycin …
Matched Categories: … Alimentary Tract and Metabolism ... Acid Reducers ... lansoprazole, tetracycline and metronidazole ... lansoprazole, amoxicillin and levofloxacin ... lansoprazole, clarithromycin and tinidazole …
Matched Products: … Foster and Thrive Acid Reducer ... Up and Up Lansoprazole ... Berkley and Jensen Lansoprazole …
Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator that causes inflammatory and...
Approved
Matched Iupac: … -5-yl]acetic acid ... 2-[(2Z)-2-[3-(dimethylamino)propylidene]-9-oxatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen …
Matched Description: … inflammatory and allergic reactions. ... Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating ... seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. …
Matched Salts cas: … 140462-76-6 …
Matched Categories: … Decongestants and Antiallergics ... Heterocyclic Compounds, 3-Ring …
Matched Products: … Eye Allergy Itch and Redness Relief ... Eye Allergy Itch and Redness Relief Twice Daily Relief ... PALLADA-NS %6.65 MG/ML NAZAL SPREY, 30 ML …
Phenazopyridine, also known as Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and its associated unpleasant symptoms such as burning and pain during urination. In the USA, this drug was previously marked by Roche but has been discontinued by the FDA. It is...
Approved
Matched Synonyms: … 2,6-Diamino-3-phenylazopyridine ... 2,6-Diamino-3-(phenylazo)pyridine ... 3-(Phenylazo)-2,6-pyridinediamine …
Matched Iupac: … 3-[(1E)-2-phenyldiazen-1-yl]pyridine-2,6-diamine …
Matched Description: … Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and ... its associated unpleasant symptoms such as burning and pain during urination. …
Matched Salts cas: … 136-40-3
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital ... AZOSILIN 500 MG/50 MG TABLET, 30 ADET …
Matched Categories: … Antipruritics and Local Anesthetics ... Genito Urinary System and Sex Hormones …
Matched Products: … Foster and Thrive Maximum Strength Urinary Pain Relief ... Foster and Thrive Neighbor Pharmacy Urinary Pain Relief …
Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. Due to its water solubility, ensulizole is commonly...
Approved
Matched Synonyms: … phenylbenzimidazole sulfonic acid
Matched Iupac: … 2-phenyl-1H-1,3-benzodiazole-6-sulfonic acid
Matched Description: … It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter ... and 148mM can be found in commercial sunscreen products [A27151]. ... Due to its water solubility, ensulizole is commonly used in products formulated to feel light and less …
Matched Mixtures name: … g and h Protect Body ... Polyglutamic Acid Dewy Sunscreen SPF 30 ... it cosmetics Your Skin But Better CC Plus Natural Matte Color Correcting Pore Refining Full Coverage …
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Matched Products: … Dolce and Gabbana The Foundation Perfect Matte Broadspectrum SPF 20 All shades ... Lancome Paris Teint Idole Ultra Care and Glow Skincare Foundation Broad Spectrum SPF 27 Sunscreen ... Sungirl SPF 3
Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro­-25-(1-methylethyl)avermectin A1a (22,23-dihydroavermectin B1b). Ivermectin is mainly used in...
Approved
Investigational
Vet approved
Matched Iupac: … ,7',19'-trioxaspiro[oxane-2,6'-tetracyclo[15.6.1.1^{4,8}.0^{20,24}]pentacosane]-10',14',16',22'-tetraen ... hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13',22'-tetramethyl-3' ... methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13',22'-tetramethyl-6-(propan-2-yl)-3' ... ,7',19'-trioxaspiro[oxane-2,6'-tetracyclo[15.6.1.1^{4,8}.0^{20,24}]pentacosane]-10',14',16',22'-tetraen …
Matched Description: … Due to a number of factors - for example, the relatively low number of patients per trial and the speed ... use for the prophylaxis and treatment of COVID-19. ... roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and
Matched Mixtures name: … Heartgard Plus Chewable Tablet for Dogs - 26 - 50 lbs ... Heartgard Plus Chewable Tablet for Dogs - Up to 25 lbs ... Heartgard Plus Chewable Tablet for Dogs - 51 - 100 lbs
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides and Pediculicides …
Matched Products: … IVOMEC Injection 1% w/v for Cattle and Sheep ... Scabioral 3 mg Tabletten ... STROCMECTOL 3 MG …
Investigational
Matched Synonyms: … recombinant adeno-associated viral (AAV) vector that contains a bio-engineered capsid (AAV-Spark100) and ... a codon-optimized expression cassette to drive expression of a secretable form of human acid a-glucosidase …
Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class,...
Approved
Investigational
Vet approved
Matched Iupac: … 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazole …
Matched Description: … Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults ... These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases ... This drug was the first clinical useful drug in its class, and its approval was followed by the formulation …
Matched Salts cas: … 95382-33-5 ... 95510-70-6 …
Matched Mixtures name: … MOVIDOL PROTEC ... CLOMETRO 7HP ... ArthroComb 75 mg/20 mg Hartkapseln mit veränderter Wirkstofffreisetzung …
Matched Categories: … Alimentary Tract and Metabolism ... Acid Reducers ... Omeprazole and enantiomer ... omeprazole, amoxicillin and rifabutin ... omeprazole, amoxicillin and clarithromycin …
Matched Products: … OMEMAX ® (OMEPRAZOL CAPSULAS POR 20 MG) ... PROTEC ... Berkley and Jensen Omeprazole …
Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy. Bacitracin was granted FDA approval on 29 July 1948.[A181997,L7748]
Approved
Vet approved
Matched Iupac: … heptaoxo-1,4,7,10,13,16,19-heptaazacyclopentacosan-21-yl]carbamoyl}-2-methylbutyl]carbamoyl}butanoic acid ... ,6R,9S,12R,15S,18R,21S)-18-(3-aminopropyl)-12-benzyl-15-[(2S)-butan-2-yl]-3-(carbamoylmethyl)-6-(carboxymethyl ... -amino-2-methylbutyl]-4,5-dihydro-1,3-thiazol-4-yl]formamido}-4-methylpentanamido]-4-{[(1S,2S)-1-{[(3S
Matched Mixtures name: … Ready America First Aid Pocket - 33 Pieces ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate ... Tribioticlc Lc Lc
Matched Categories: … Amino Acids, Peptides, and Proteins ... Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids
Matched Products: … Up and Up First Aid Antibiotic ... Up and Up Bacitracin first aid ... Live Better Bacitracin Zinc …
Investigational
Matched Synonyms: … CD4+ CD8+ T CELLS ARE DERIVED FROM ISOLATED BLOOD OF THE PATIENT AND ARE TRANSDUCED WITH NON-REPLICATIVE …
Investigational
Matched Synonyms: … AUTOLOGOUS CD4+ AND CD8+ T CELLS, ENRICHED FROM PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS) TRANSDUCED …
Tilmicosin is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia haemolytica.
Investigational
Vet approved
Matched Iupac: … yl]oxy}-7-{2-[(3R,5S)-3,5-dimethylpiperidin-1-yl]ethyl}-16-ethyl-4-hydroxy-15-({[(2R,3R,4R,5R,6R)-5-hydroxy ... (4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-{[(2R,3R,4S,5S,6R)-4-(dimethylamino)-3,5-dihydroxy-6-methyloxan-2- ... -3,4-dimethoxy-6-methyloxan-2-yl]oxy}methyl)-5,9,13-trimethyl-1-oxacyclohexadeca-11,13-diene-2,10-dione …
Matched Description: … It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory …
Matched Salts cas: … 137330-13-3
Matched Products: … Tilmovet® 200 g/kg Premix for Medicated Feeding Stuff for Pigs and Rabbits ... TP-Mecotil 300 Sol Tilmicosin Phosphate 300mg/ml Solution ... Timecox 200 Sol Tilmicosin 200g/L
Approved
Matched Synonyms: … Sus scrofa subcutaneous fat …
A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma. It has been approved by FDA for use in externally applied drugs...
Approved
Matched Synonyms: … D and C Yellow No. 7 ... D&C Yellow No. 7 ... 9-(o-carboxyphenyl)-6-hydroxy-3H-xanthen-3-one …
Matched Iupac: … 3',6'-dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one …
Matched Description: … and corneal trauma. ... A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline ... It has been approved by FDA for use in externally applied drugs and cosmetics. …
Matched Mixtures name: … Fluress Liq Oph ... Fluorescein Sodium and Proparacaine Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride …
Matched Categories: … Indicators and Reagents ... Heterocyclic Compounds, 3-Ring …
Approved
Vet approved
Matched Synonyms: … Cortisol 21-acetate ... Hydrocortisone acetate ... Hydrocortisone 21-acetate
Matched Name: … Hydrocortisone acetate
Matched Iupac: … 2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H ... ,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate
Matched Mixtures name: … Sopamycetin/hc Susp ... Ana-Lex ... Otizol HC Liq
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … American Safety and First Aid ... HIPOKORT %0.5 KREM 30 G ... HIPOKORT %0.5 MERHEM, 30 GR …
Displaying drugs 301 - 325 of 5910 in total