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Displaying drugs 301 - 325 of 2780 in total

PRGN-3006

PRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface.
Investigational
Matched Synonyms: … genetically modified using a non-viral system to express a CD33 CAR, membrane bound Interleukin-15, and …
Matched Description: … genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and …

Docusate

Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation . Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass . Docusate can be orally or rectally administered. Docusate is on the World...
Approved
Matched Iupac: … 1,4-bis[(2-ethylhexyl)oxy]-1,4-dioxobutane-2-sulfonic acid …
Matched Description: … Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and …
Matched Mixtures name: … SENNA LEAF and DOCUSATE SODIUM ... Taron-prex Prenatal ... PNV Ferrous Fumarate Docusate Folic Acid …
Matched Categories: … Alimentary Tract and Metabolism ... Softener and Emollient Laxatives …
Matched Products: … Up and up stool softener ... Stool Softener easy and gentle ... Taro-docusate …

Demplatin pegraglumer

Demplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer).
Investigational
Matched Synonyms: … A micelle drug formulation composed of cisplatin and mPEG-poly(l-Glu) diblock copolymer with 1,3-propanediyl …
Matched Description: … pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic …

Levomenthol

Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration. Menthol mediates anesthetic properties and...
Approved
Matched Description: … . (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration ... Menthol mediates anesthetic properties and anti-irritating properties locally, thus it is widely used …
Matched Mixtures name: … X-tar Shampoo ... SEE FULL OIL ... Medicated Body Powder …
Matched Categories: … Antipruritics and Local Anesthetics ... Basic Lotions and Liniments ... Herbs and Natural Products ... Other Cold and Cough Preparations …
Matched Products: … Musle and Joint ... Performance and Recovery …

Dexpanthenol

Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that...
Approved
Matched Description: … Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and ... Due to its good penetration and high local concentrations, dexpanthanol is used in many topical products ... , such as ointments and lotions for treatment of dermatological conditions to relieve itching or promote …
Matched Mixtures name: … Somarexin and C 1000 ... B Complex W C and B12 Inj ... CH6 Perfumed Aloforthya Peony and the sunset …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Alimentary Tract and Metabolism ... Vitamin D and Analogues ... Preparations for Treatment of Wounds and Ulcers …
Matched Products: … Eros Aqua Sensations and Care Woman ... DEXPANTHENOL ACIS WUND+HEI …

Vanglusagene ensiparvovec

Investigational
Matched Synonyms: … recombinant adeno-associated viral (AAV) vector that contains a bio-engineered capsid (AAV-Spark100) and ... a codon-optimized expression cassette to drive expression of a secretable form of human acid a-glucosidase …

Ibuprofen

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and...
Approved
Matched Synonyms: … 4-isobutylhydratropic acid ... (±)-p-isobutylhydratropic acid ... (±)-2-(p-isobutylphenyl)propionic acid …
Matched Iupac: … 2-[4-(2-methylpropyl)phenyl]propanoic acid …
Matched Description: … Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered ... [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development ... in the UK in 1969 and USA in 1974. …
Matched Mixtures name: … Motrin Platinum Muscle & Body ... Cimetidine 5% / Ibuprofen 2% / Salicylic Acid 17% ... Oxycodone Hydrochloride and Ibuprofen …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Antiinflammatory and Antirheumatic Products ... Ibuprofen and isomer ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Help I Have an Aching Body ... Sound Body Ibuprofen ... Sound Body Childrens Ibuprofen …

Bacitracin

Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy. Bacitracin was granted FDA approval on 29 July 1948.[A181997,L7748]
Approved
Vet approved
Matched Iupac: … heptaoxo-1,4,7,10,13,16,19-heptaazacyclopentacosan-21-yl]carbamoyl}-2-methylbutyl]carbamoyl}butanoic acid …
Matched Description: … Bacitracin is a combination of at least 9 bacitracins. …
Matched Mixtures name: … Pink Eye Ointment ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids …
Matched Products: … Up and Up First Aid Antibiotic ... Up and Up Bacitracin first aid ... Taro-bacitracin Ointment 500units/gm …

Omeprazole

Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class,...
Approved
Investigational
Vet approved
Matched Description: … Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults ... These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases ... This drug was the first clinical useful drug in its class, and its approval was followed by the formulation …
Matched Mixtures name: … Topcare Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate …
Matched Categories: … Sulfur Compounds ... Alimentary Tract and Metabolism ... Acid Reducers ... Omeprazole and enantiomer ... omeprazole, amoxicillin and rifabutin …
Matched Products: … Sound Body Omeprazole ... Up and Up Omeprazole ... Berkley and Jensen Omeprazole …

Orvacabtagene autoleucel

Investigational
Matched Synonyms: … CD4+ CD8+ T CELLS ARE DERIVED FROM ISOLATED BLOOD OF THE PATIENT AND ARE TRANSDUCED WITH NON-REPLICATIVE …

Relmacabtagene autoleucel

Investigational
Matched Synonyms: … AUTOLOGOUS CD4+ AND CD8+ T CELLS, ENRICHED FROM PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS) TRANSDUCED …

Fimaporfin

Investigational
Matched Synonyms: … , mixture of three isomers a, b and c (25%, 50%, 25%) ... 4,4'-(15,20-diphenyl-7,8(or 12,13 or 17,18)-dihydro-21h,23h-porphine-5,10-diyl)bisbenzenesulfonic acid ... Benzenesulfonic acid, 4,4'-(7,8(or 17,18)-dihydro-10,15(or 15,20)-diphenyl-21h,23h-porphine-5,20(or 5,10 …

Pectin

Pectin is a heteropolysaccharide commercially derived from the cell wall of higher plants. It is composed of partially methylated polygalacturonic acid units linked in the positions 1-4. The carboxylic group of the constituents of pectin can exist in the form of esters, free acids, ammonium, potassium or sodium salts or...
Approved
Investigational
Vet approved
Matched Description: … , ammonium, potassium or sodium salts or as acid amides. ... [A32327] It is composed of partially methylated polygalacturonic acid units linked in the positions 1 ... [L1961] The carboxylic group of the constituents of pectin can exist in the form of esters, free acids …
Matched Mixtures name: … Cepacol Sore Throat and Coating ... Kaolin and Pectin Susp ... Sucrets Complete Sore Throat, Cough and Irritation …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … Ludens Honey and Berry …

Evorpacept

evorpacept is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)).
Investigational
Matched Synonyms: … of human signal regulatory protein alpha (SIRPalpha) variant 1 (v1) genetically linked to a modified and …
Matched Description: … is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Mucor circinelloides f. circinelloides

Mucor circinelloides f. circinelloides allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, mucor circinelloides f. circinelloides ... Mucor circinelloides f. circinelloides whole …

Verpasep caltespen

Verpasep caltespen is a recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from Mycobacterium bovis, and the human papilloma viral (HPV) protein E7. Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be used to design vaccines against a...
Investigational
Matched Synonyms: … Recombinant fusion protein of Mycobacterium bovis BCG Hsp65 and HPV16 E7 …
Matched Description: … E7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen ... recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from _Mycobacterium bovis_, and ... Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be …

Chlorhexidine

Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of...
Approved
Vet approved
Withdrawn
Matched Description: … Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental ... [L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today. ... [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two …
Matched Mixtures name: … ICEKING Skin Expert Refreshing Body Roller ... Spectro Tar Antiseptic Shampoo ... QCare Rx Oral Cleansing and Suctioning System, Q4 …
Matched Salts name: … Chlorhexidine hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Biguanides and Amidines ... Antiseptics and Disinfectants ... Antiinfectives and Antiseptics for Local Oral Treatment ... Mouthwashes and Gargles …
Matched Products: … 3M AVAGARD 9232 ANTISEPTIC HAND AND BODY WASH CLORHEXIDINE GLUCONATE 2% W/W SOLUTION BOTTE . ... Foster and Thrive ... Antiseptic Body Cleanser …

Follitropin

Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78...
Approved
Matched Description: … The alpha- and beta- subunits have 92 and 111 amino acids. ... 7 and Asn 24. ... Numerous physio-chemical tests and bioassays indicate that follitropin beta and follitropin alpha are …
Matched Mixtures name: … Pergoveris 150IU/75IU powder and solvent for solution for injection ... Pergoveris Powder and Solvent for Solution for Injection 150iu/75iu ... MENOGON 75 IU Powder and Solvent for solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … GONAL-F® 450 IU/0.75 ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... GONAL-F® 75 IU (5.5MCG) POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Atidarsagene autotemcel

Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC ... transduced with lentiviral vector which encodes for the aryl Sulfatase A complimentary deoxyribonucleic acid …
Matched Description: … Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …

Mometasone furoate

Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295]. It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and higher than many other corticosteroids as well . Mometasone furoate is formulated as a dry powder...
Approved
Investigational
Vet approved
Matched Description: … Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and ... It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than ... Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different …
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 2% / Mometasone Furoate 0.1% / Niacinamide 4% …
Matched Categories: … formoterol and mometasone …
Matched Products: … Nasonex Allergy and Congestion ... Up and Up Allergy ... Nasal Allergy and Congestion Relief …

Tefidsogene civaparvovec

Tefidsogene civaparvovec, formerly known as SB-913, is an investigational therapy for genome editing. It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes. Developed by Sangamo...
Experimental
Matched Synonyms: … IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUS EXONS 2-9 FROM HIDS AND …
Matched Description: … It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system …

Tilmicosin

Tilmicosin is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia haemolytica.
Investigational
Vet approved
Matched Description: … It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory …
Matched Products: … Tilmovet® 200 g/kg Premix for Medicated Feeding Stuff for Pigs and Rabbits …

Nogapendekin alfa

Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Fusion protein consisting of il-15n72d and il-15rasu/fc ... Human interleukin 15 (72-aspartic acid) (human il-15 n72>d isoform) …
Matched Description: … 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG ... Nogapendekin alfa, in combination with inbakicept, mimics the actions of IL-15, , stimulating the activation and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Elapegademase

Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED ON N.ALPHA..1ALANINE AND ... 356)-PEPTIDE, PRODUCED IN ESCHERICHIA COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND …
Matched Description: … as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues ... [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Antineoplastic and Immunomodulating Agents …

Ceftazidime

Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Matched Description: … a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and ... through inhibition of essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ... [L32935] Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone …
Matched Categories: … Sulfur Compounds …
Matched Products: … Ceftazidime and Dextrose ... CEFTAZIDIME ALVOGEN POWDER FOR SOLUTION FOR INJECTION AND INFUSION 1G/ VIAL …
Displaying drugs 301 - 325 of 2780 in total