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Displaying drugs 301 - 325 of 5543 in total
Investigational
Matched Synonyms: … , mixture of three isomers a, b and c (25%, 50%, 25%) ... 4,4'-(15,20-diphenyl-7,8(or 12,13 or 17,18)-dihydro-21h,23h-porphine-5,10-diyl)bisbenzenesulfonic acid ... Benzenesulfonic acid, 4,4'-(7,8(or 17,18)-dihydro-10,15(or 15,20)-diphenyl-21h,23h-porphine-5,20(or 5,10 …
Investigational
Matched Synonyms: … a codon-optimized expression cassette to drive expression of a secretable form of human acid a-glucosidase ... recombinant adeno-associated viral (AAV) vector that contains a bio-engineered capsid (AAV-Spark100) and
Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Human interleukin 15 (72-aspartic acid) (human il-15 n72>d isoform) ... Fusion protein consisting of il-15n72d and il-15rasu/fc ... Superagonist interleukin-15:interleukin-15 receptor alphasu/fc fusion complex alt-803 …
Matched Description: … 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG ... Nogapendekin alfa, in combination with inbakicept, mimics the actions of IL-15, , stimulating the activation and
Matched Categories: … Amino Acids, Peptides, and Proteins …
A vitamin-like antioxidant.
Approved
Investigational
Nutraceutical
Matched Synonyms: … D-thioctic acid ... Thioctic acid D-form ... (R)-1,2-dithiolane-3-valeric acid
Matched Name: … Lipoic acid
Matched Iupac: … 5-[(3R)-1,2-dithiolan-3-yl]pentanoic acid
Matched Mixtures name: … Folic-K ... Essential Pro ALPHA-G Q10 Capsule ... Folica-V …
Matched Categories: … Fatty Acids ... Carboxylic Acids ... thioctic acid ... Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Products: … ALPHA LIPOIC ACID CAPSULE ... GNC-ALPHA LIPOIC ACID 100MG ... LIPO-X (ALPHA LIPOIC ACID 50MG) …
Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and cause neurologic problems, cerebral edema, coma, and death. Carglumic acid was...
Approved
Matched Synonyms: … Carglumic acid ... Acide carglumique ... Acidum carglumicum …
Matched Name: … Carglumic acid
Matched Iupac: … (2S)-2-(carbamoylamino)pentanedioic acid
Matched Description: … Carglumic acid was approved by the U.S. Food and Drug Administration (FDA) on 18 March 2010. ... Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl ... cause neurologic problems, cerebral edema, coma, and death. …
Matched Categories: … Amino Acids and Derivatives ... Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids, Acidic ... Amino Acids
Matched Products: … Carglumic Acid ... Carglumic acid ... ACIDO CARGLUMICO WAYMADE …
Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … deoxyribonucleic acid sequence ... Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC ... Autologous CD34+ cells transduced with lentiviral vector which encodes for the aryl Sulfatase A complimentary …
Matched Description: … Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Mucor circinelloides f. lusitanicus allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, mucor circinelloides f. lusitanicus …
Investigational
Matched Synonyms: … antibody-drug conjugate comprised of a human aglycosylated anti-CD74 IgG1 antibody (SP7219) and two non-cleavable …
PRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface.
Investigational
Matched Synonyms: … genetically modified using a non-viral system to express a CD33 CAR, membrane bound Interleukin-15, and
Matched Description: … genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … POLY(OXY-1,2-ETHANEDIYL), .ALPHA.-CARBOXY-.OMEGA. ... PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED ON N.ALPHA..1ALANINE AND ... COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND ON N6 OF LYSYL RESIDUES (K) WITH AN …
Matched Description: … as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues ... [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Antineoplastic and Immunomodulating Agents …
Demplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer).
Investigational
Matched Synonyms: … A micelle drug formulation composed of cisplatin and mPEG-poly(l-Glu) diblock copolymer with 1,3-propanediyl …
Matched Description: … pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic …
Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant,...
Approved
Investigational
Nutraceutical
Matched Synonyms: … (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid ... 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid (ECL) ... Retinoic acid
Matched Iupac: … (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
Matched Description: … Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of [vitamin ... activates nuclear receptors to regulate epithelial cell growth and differentiation. ... [A257689] Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant, and free radical-scavenging …
Matched Mixtures name: … Imiquimod 5% / Salicylic Acid 30% / Tretinoin 0.1% ... Ascorbyl Palmitate 2% / Hyaluronic Acid Sodium Salt 0.2% / Niacinamide 5% / Tretinoin 0.025% ... Hyaluronic Acid Sodium Salt 0.5% / Niacinamide 4% / Tretinoin 0.1% …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cell Stimulants and Proliferants ... Vitamins (Fat Soluble) …
Matched Products: … TRE % 0.05 KREM , 30 G ... Vitamin A Acid ... ACIDO RETINOICO …
evorpacept is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)).
Investigational
Matched Synonyms: … protein alpha (SIRPalpha) variant 1 (v1) genetically linked to a modified and inactive Fc domain of ... A CD47-binding, fusion protein containing a high affinity engineered D1 domain of human signal regulatory …
Matched Description: … is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro­-25-(1-methylethyl)avermectin A1a (22,23-dihydroavermectin B1b). Ivermectin is mainly used in...
Approved
Investigational
Vet approved
Matched Iupac: … hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13',22'-tetramethyl-3' ... methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13',22'-tetramethyl-6-(propan-2-yl)-3' …
Matched Description: … Due to a number of factors - for example, the relatively low number of patients per trial and the speed ... With the advent of 2020 and the COVID-19 pandemic, ivermectin began garnering notoriety due to its off-label ... use for the prophylaxis and treatment of COVID-19. …
Matched Mixtures name: … Eqvalan Duo Oral Paste for Horse …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides and Pediculicides …
Matched Products: … IVOMEC Injection 1% w/v for Cattle and Sheep ... Scabioral 3 mg Tabletten ... STROCMECTOL 3 MG …
Approved
Investigational
Matched Synonyms: … alpha-Hydroxyacetic acid ... Glycollic acid ... 2-Hydroxyacetic acid
Matched Name: … Glycolic acid
Matched Iupac: … 2-hydroxyacetic acid
Matched Mixtures name: … CREMA CON ACIDO GLICOLICO AL 8% …
Matched Categories: … Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids
Matched Products: … Glycolic Acid ... ACIDO GLICOLICO OVOCELL ... Village 11 Factory Relax Day Aha Exfoliating Body …
Chenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid (DB01586). Chenodeoxycholic acid is a bile acid naturally found in the body. It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol in the liver and absorption in the intestines, which helps to decrease the formation...
Approved
Matched Synonyms: … Chenic acid ... Chenocholic acid ... Acido chenodeoxicholico …
Matched Name: … Chenodeoxycholic acid
Matched Iupac: … [a]phenanthren-1-yl]pentanoic acid ... (4R)-4-[(1R,3aS,3bR,4R,5aS,7R,9aS,9bS,11aR)-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta …
Matched Description: … Chenodeoxycholic acid is a bile acid naturally found in the body. ... It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol ... in the liver and absorption in the intestines, which helps to decrease the formation of gallstones. …
Matched Categories: … Bile Acids and Salts ... Bile acids and derivatives ... Cholic Acids ... Bile Acid Preparations ... chenodeoxycholic acid
Matched Products: … ACIDO CHENODESOSSICOLICO LEADIANT ... Chenodeoxycholic Acid Leadiant …
Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. Due to its water solubility, ensulizole is commonly...
Approved
Matched Synonyms: … phenylbenzimidazole sulfonic acid
Matched Iupac: … 2-phenyl-1H-1,3-benzodiazole-6-sulfonic acid
Matched Description: … Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that ... Due to its water solubility, ensulizole is commonly used in products formulated to feel light and less ... It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter …
Matched Mixtures name: … Polyglutamic Acid Dewy Sunscreen SPF 30 ... Octisalate,octocrylene,octinoxate,zinc Oxide,titanium Dioxide,ensulizole ... Neck Decollete Hand Arm Day Reparative Hydration Rescue and Reprogram Broad Spectrum SPF 35 Sunscreen …
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Matched Products: … Dolce and Gabbana The Foundation Perfect Matte Broadspectrum SPF 20 All shades ... Lancome Paris Teint Idole Ultra Care and Glow Skincare Foundation Broad Spectrum SPF 27 Sunscreen ... Covergirl Outlast All Day Stay Fabulous 3-IN-1 Foundation …
Tefidsogene civaparvovec, formerly known as SB-913, is an investigational therapy for genome editing. It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes. Developed by Sangamo...
Experimental
Matched Synonyms: … (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUS EXONS 2-9 FROM HIDS AND A SPLICE ACCEPTOR SITE ... ADENO-ASSOCIATED VIRUS TYPE 2/6 (RAAV REP2-CAP6) VECTOR, WHICH CONTAINS A PROMOTER-LESS HUMAN IDURONATE 2-SULFATASE
Matched Description: … It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system ... that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes …
A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma. It has been approved by FDA for use in externally applied drugs...
Approved
Matched Synonyms: … D and C Yellow No. 7 ... D&C Yellow No. 7 ... 9-(o-carboxyphenyl)-6-hydroxy-3H-xanthen-3-one …
Matched Iupac: … 3',6'-dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one …
Matched Description: … A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline ... and corneal trauma. ... It has been approved by FDA for use in externally applied drugs and cosmetics. …
Matched Mixtures name: … Fluorescein Sodium and Proparacaine Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride
Matched Categories: … Indicators and Reagents ... Diagnostic Dye ... Heterocyclic Compounds, 3-Ring …
Matched Products: … Dry Eye Test …
Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the levorotatory form (levopanthenol). While pantothenic acid is optically active, only the dextrorotatory...
Approved
Matched Synonyms: … DL-panthenol ... DL-Pantothenol …
Matched Iupac: … 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide …
Matched Description: … Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an ... Due to its good penetration and high local concentrations, dexpanthanol is used in many topical products ... While pantothenic acid is optically active, only the dextrorotatory form ([DB09357]) is biologically …
Matched Mixtures name: … Therapytion Nokmosu Sensitive and Dry Hair ... Therapytion Nokmosu Neutral and oily Hair ... Adeks - Dps
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Matched Products: … BABOR Baborganic Calm and Relax ... DR. BABOR Ultimate Vitamin CP ... DR. BABOR DERMA CELLULAR Ultimate Firming Eye …
Investigational
Matched Synonyms: … CD4+ CD8+ T CELLS ARE DERIVED FROM ISOLATED BLOOD OF THE PATIENT AND ARE TRANSDUCED WITH NON-REPLICATIVE …
The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Synonyms: … (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol ... beta-D-Adenosine ... 9-beta-D-Ribofuranosidoadenine …
Matched Iupac: … (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Description: … L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole] and ... [L31998] Adenosine was granted FDA approval on 30 October 1989.[L31978] …
Matched Mixtures name: … Dr. sunmi care Duel Hyaluronic Acid Essence ... Jayjun Collagen Skin Fit Mask Step 01 Hyaluronic Acid Essence ... H ALPHA 30 Skin …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … Mizon Hyaluronic Acid 100 ... rootree Treetherapy Rejuvenating Eye and Neck Treatment ... misoli Power Snail and Collagen Hydrog el Mask Pack …
Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration. Menthol mediates anesthetic properties and...
Approved
Matched Synonyms: … (−)-(1R,3R,4S)-menthol ... (1R,3R,4S)-(−)-menthol …
Matched Description: … . (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration ... Menthol mediates anesthetic properties and anti-irritating properties locally, thus it is widely used …
Matched Mixtures name: … Orajel 3X Medicated For Toothache and Gum ... Salonpas 30 ... Salonpas 30 Hot …
Matched Categories: … Antipruritics and Local Anesthetics ... Basic Lotions and Liniments ... Herbs and Natural Products ... Other Cold and Cough Preparations …
Matched Products: … Musle and Joint ... Performance and Recovery ... BIOFREEZE PAIN RELIEVING GEL 3.5%W/W …
Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid. It is a topical analgesic used for temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and bruises. Unlike other topical analgesics, trolamine...
Approved
Matched Iupac: … 2-[bis(2-hydroxyethyl)amino]ethan-1-ol; 2-hydroxybenzoic acid
Matched Description: … Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid ... Triethanolamine neutralizes the acidity of the salicylic acid. ... temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids
Matched Products: … Up and Up Pain Relief Odorless ... Up and Up Odor-free Pain Relieving Cream ... DCH Arthritis Relief …
Pectin is a heteropolysaccharide commercially derived from the cell wall of higher plants. It is composed of partially methylated polygalacturonic acid units linked in the positions 1-4. The carboxylic group of the constituents of pectin can exist in the form of esters, free acids, ammonium, potassium or sodium salts or...
Approved
Investigational
Vet approved
Matched Description: … , ammonium, potassium or sodium salts or as acid amides. ... [A32327] It is composed of partially methylated polygalacturonic acid units linked in the positions 1 ... [L1961] The carboxylic group of the constituents of pectin can exist in the form of esters, free acids
Matched Mixtures name: … Cepacol Sore Throat and Coating ... Kaolin and Pectin Susp ... Sucrets Complete Sore Throat, Cough and Irritation …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … Ludens Honey and Berry …
Displaying drugs 301 - 325 of 5543 in total