Displaying drugs 301 - 325 of 3264 in total
Krypton Kr 81m
Approved
Xenon Xe-127
Approved
Fluoride ion
Having a chemical formula of F−, fluoride ion is the simplest inorganic, monatomic anion of fluorine with basic properties. It is considered a trace element. Fluoride ions are found in various minerals but are only present in trace amounts in water. Its various salt forms and minerals play numerous roles...
Approved
Iodine
Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159]
Approved
Investigational
Zalcitabine
A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the elongation of DNA chains, thus resulting in the termination of viral DNA growth. The compound is...
Approved
Investigational
Valdecoxib
Valdecoxib was removed from the Canadian, U.S., and E.U. markets in 2005 due to concerns about a possible increased risk of heart attack and stroke.
Approved
Investigational
Withdrawn
Matched Categories: … Analgesics, Non-Narcotic ... Anti-Inflammatory Agents, Non-Steroidal ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Cetuximab
Cetuximab is a recombinant chimeric human/mouse IgG1 monoclonal antibody that competitively binds to epidermal growth factor receptor (EGFR) and competitively inhibits the binding of epidermal growth factor (EGF). EGFR is a member of the ErbB family of receptor tyrosine kinases found in both normal and tumour cells; it is responsible...
Approved
Matched Description: … [A227963,L39045] It has also been investigated in advanced colorectal cancer, EGFR-expressing non-small …
Azelastine
Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic conjunctivitis.[L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first...
Approved
Matched Categories: … Histamine H1 Antagonists, Non-Sedating …
Antilymphocyte immunoglobulin (horse)
Equine anti-thymocyte globulin is composed of purified gamma globulin containing primarily IgG against human thymus lymphocytes. It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen. The result is polyclonal IgG that...
Approved
Investigational
Matched Description: … system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen. ... It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune ... available, which differ in the source of inoculated animal (rabbit, horse, or pig) and in the type of antigen …
Sodium zirconium cyclosilicate
Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that acts as a highly selective potassium removing agent. It is administered orally and is odorless, tasteless, and stable at room temperature. Approval...
Approved
Investigational
Matched Description: … zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed …
Ketorolac
Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution. It's analgesic properties make it a useful pain management tool across many settings including postoperative pain, rheumatoid arthritis, osteoarthritis, menstrual disorders, headaches, spinal and soft tissue pain,...
Approved
Matched Description: … Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral …
Matched Categories: … Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) ... Analgesics, Non-Narcotic ... Non COX-2 selective NSAIDS ... Anti-Inflammatory Agents, Non-Steroidal ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Categories: … Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) ... Analgesics, Non-Narcotic ... Non COX-2 selective NSAIDS ... Anti-Inflammatory Agents, Non-Steroidal ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Apricot
Apricot allergenic extract is used in allergenic testing.
Approved
Matched Categories: … Non-Standardized Food Allergenic Extract …
Hexafluronium
Hexafluronium bromide is a neuromuscular blocking agent used in anesthesiology to prolong and potentiate the skeletal muscle relaxing action of suxamethonium during surgery. It is known to bind and block the activity of plasma cholinesterases.
Approved
Mefenamic acid
A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Approved
Matched Description: … A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties …
Matched Categories: … Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) ... Analgesics, Non-Narcotic ... Anti-Inflammatory Agents, Non-Steroidal ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Categories: … Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) ... Analgesics, Non-Narcotic ... Anti-Inflammatory Agents, Non-Steroidal ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Lumiracoxib
Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID). On August 11, 2007, Australia's Therapeutic Goods Administration (TGA, the Australian equivalent of the FDA) cancelled the registration of lumiracoxib in Australia due to concerns that it may cause liver failure. New Zealand and Canada have also followed suit in recalling...
Approved
Investigational
Matched Description: … Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID). …
Matched Categories: … Analgesics, Non-Narcotic ... Anti-Inflammatory Agents, Non-Steroidal ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Categories: … Analgesics, Non-Narcotic ... Anti-Inflammatory Agents, Non-Steroidal ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Pegaptanib
Pegaptanib is a polynucleotide aptamer. Pegatinib aids neovascular age-related macular degeneration by binding to VEGF which in order reduces angiogenesis and vessel permeability.
Pegaptanib was granted FDA approval on 17 September 2004.
Approved
Investigational
Bromocriptine
Bromocriptine mesylate is a semisynthetic ergot alkaloid derivative with potent dopaminergic activity. It inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia. Bromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Syndrome, as well as the treatment of acromegaly. Bromocriptine has been...
Approved
Investigational
Withdrawn
Cisatracurium
Cisatracurium is a non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available in its salt form, cisatracurium besylate.[A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly used neuromuscular blocking agents in intensive care.[A253592,A253597]. Cisatracurium acts on cholinergic receptors, blocking neuromuscular transmission. This action is...
Approved
Investigational
Matched Description: … Cisatracurium is a non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available …
Flurbiprofen
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Categories: … Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) ... Analgesics, Non-Narcotic ... Non COX-2 selective NSAIDS ... Anti-Inflammatory Agents, Non-Steroidal ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Ixabepilone
Ixabepilone is an epothilone B analog developed by Bristol-Myers Squibb as a cancer drug. It was FDA approved on October 16, 2007, for the treatment of unresponsive aggressive metastatic or locally advanced breast cancer. Ixabepilone is administered through injection, and will be marketed under the trade name Ixempra. Ixabepilone is...
Approved
Investigational
Bacitracin
Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy. Bacitracin was granted FDA approval on 29 July 1948.[A181997,L7748]
Approved
Vet approved
Sulfasalazine
Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal anti-inflammatory drugs. It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA).[L39065, A255582] Metabolized by intestinal bacteria, sulfasalazine is broken down into mesalazine and sulfapyridine, 2 compounds that carry out the main pharmacological...
Approved
Matched Description: … Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal …
Matched Categories: … Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) ... Non COX-2 selective NSAIDS ... Anti-Inflammatory Agents, Non-Steroidal …
Matched Categories: … Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) ... Non COX-2 selective NSAIDS ... Anti-Inflammatory Agents, Non-Steroidal …
Azacitidine
Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine. One of them is the induction of cytotoxicity. As an analogue of cytidine, it...
Approved
Investigational
Matched Description: … [A1407] Due to its anti-neoplastic activity and its ability to inhibit methylation in replicating DNA …
Chlorambucil
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Approved
Displaying drugs 301 - 325 of 3264 in total