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Displaying drugs 326 - 350 of 3038 in total
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED ON N.ALPHA..1ALANINE AND ... 356)-PEPTIDE, PRODUCED IN ESCHERICHIA COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND
Matched Description: … as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues ... [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Antineoplastic and Immunomodulating Agents …
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Matched Description: … a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and ... through inhibition of essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ... [L32935] Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone …
Matched Salts name: … Ceftazidime sodium
Matched Products: … Ceftazidime and Dextrose ... CEFTAZIDIME ALVOGEN POWDER FOR SOLUTION FOR INJECTION AND INFUSION 1G/ VIAL …
RP-L102 is a lentiviral vector carrying the Fanconi Anemia-A (FANCA) gene currently being developed by Rocket Pharmaceuticals for the treatment of Fanconi anemia type A
Investigational
Matched Synonyms: … Autologous CD34+-enriched Hematopoietic Stem and Progenitor Cells Transduced with Lentiviral Vector Carrying …
Investigational
Matched Synonyms: … CYCLIZED P12 (PEPTIDE BOND BETWEEN THE CARBOXY AND AMINO-TERMINAL ENDS OF THE LINEAR PEPTIDE PSHISKYILRWRPK …
Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Fusion protein consisting of il-15n72d and il-15rasu/fc ... Human interleukin 15 (72-aspartic acid) (human il-15 n72>d isoform) …
Matched Description: … 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG ... Nogapendekin alfa, in combination with inbakicept, mimics the actions of IL-15, , stimulating the activation and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Pacmilimab is under investigation in clinical trial NCT04596150 (Study to Evaluate the Safety and Antitumor Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer).
Investigational
Matched Synonyms: … HUMAN MONOCLONAL CX-072 .GAMMA.4-CHAIN), DISULFIDE WITH PRODOMAIN PROTEIN (SYNTHETIC MASKING MOIETY AND
Matched Description: … Pacmilimab is under investigation in clinical trial NCT04596150 (Study to Evaluate the Safety and Antitumor ... Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer). …
C-CAR039 is an autologous Chimeric Antigen Receptors (CAR) T-cell therapy expressing CD19/CD20 bi-specific CAR.
Investigational
Matched Synonyms: … , non-replicating lentiviral vector, encoding a bispecific chimeric antigen receptor targeting CD19 and
Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine.[A187691,L9851] It can be sourced from coffee beans, but also occurs naturally in...
Approved
Matched Description: … variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and ... Caffeine is similar in chemical structure to [Theophylline] and [Theobromine]. ... [A187694] Caffeine is beneficial in preventing and treating apnea and bronchopulmonary dysplasia in newborns …
Matched Mixtures name: … Nu-acetaco #1 ... Apo-acetaco #1 ... ACETAN PLUS TABLETAS …
Matched Categories: … caffeine and sodium benzoate ... Carboxylic Acids ... Anorexigenic Agents & Respiratory and CNS Stimulants ... Caffeine and Caffeine Containing Products ... Tricarboxylic Acids
Matched Products: … Caffeine and Sodium Benzoate …
Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels of...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX, II, VII and X in combination …
Matched Description: … Coagulation factors are purified from pooled human plasma and subsequently sterilized and treated. ... include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and ... For example, Kcentra (FDA) also contains the antithrombotic proteins C and S, while Bebulin VH (FDA) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro­-25-(1-methylethyl)avermectin A1a (22,23-dihydroavermectin B1b). Ivermectin is mainly used in...
Approved
Investigational
Vet approved
Matched Description: … use for the prophylaxis and treatment of COVID-19. ... roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and ... also be effective against other worm infestations (such as strongyloidiasis, ascariasis, trichuriasis and
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides and Pediculicides …
Matched Products: … IVOMEC Injection 1% w/v for Cattle and Sheep …
Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death. In August 2017, a combination antibacterial therapy under the market name vabomere...
Approved
Investigational
Matched Synonyms: … pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Matched Iupac: … pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Matched Description: … It is active against Gram-positive and Gram-negative bacteria. ... Vabomere consists of meropenem and [DB12107] and is intravenously admininstered. ... Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis …
Matched Salts name: … Meropenem sodium
Matched Categories: … meropenem and vaborbactam …
Matched Products: … Meropenem and Sodium Chloride ... Meropenem for Injection USP and Sodium Chloride Injection USP ... MEROPENEM ACIC
A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma. It has been approved by FDA for use in externally applied drugs...
Approved
Matched Synonyms: … D and C Yellow No. 7 …
Matched Description: … and corneal trauma. ... A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline ... medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries …
Matched Mixtures name: … Fluorescein Sodium and Proparacaine Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride …
Matched Salts name: … Fluorescein sodium
Matched Categories: … Indicators and Reagents …
Matched Products: … Fluorescein Sodium ... FLUORESCEINA SODICA ... FLUORESCEINA SODICA 10% …
Barium sulfate is an inorganic compound with the chemical formula BaSO4 . Barium sulfate occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield . This drug is used as a contrast agent in...
Approved
Matched Synonyms: … Bario sulfato ... Barium sulfate
Matched Name: … Barium sulfate
Matched Iupac: … barium(2+) sulfate
Matched Description: … Barium sulfate is ingested by mouth or administered rectally and combined with granules of effervescent ... and high level of clearance from the body [FDA label]. ... It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation …
Matched Mixtures name: … E-Z HD SULFATODE BARIO PARA SUSPENSION ... E-Z HD SULFATODE BARIO PARA SUSPENSION ... E-Z HD SULFATODE BARIO PARA SUSPENSION …
Matched Categories: … Sulfur Acids ... Sulfuric Acids ... Sulfates ... Barium Sulfate Containing X-Ray Contrast Media ... barium sulfate with suspending agents …
Matched Products: … Hd 85 Barium Sulfate Susp 51% ... Tomo Cat Barium Sulfate Susp 5% ... Hd200 Plus Barium Sulfate for Susp 98% …
Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form. Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used commercially...
Approved
Investigational
Matched Synonyms: … Milk of magnesia ... Magnesio hidróxido ... Magnesii hydroxidum …
Matched Name: … Magnesium hydroxide …
Matched Iupac: … magnesium(2+) dihydroxide …
Matched Description: … Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used ... Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. ... Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable …
Matched Mixtures name: … PMS-alumina Mag and Simethicone Sus ... Omeprazole, Sodium Bicarbonate, Magnesium Hydroxide ... Omeprazole, Sodium Bicarbonate, Magnesium Hydroxide …
Matched Categories: … Aluminum and magnesium containing antacids ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... Antacids and Adsorbents …
Matched Products: … Milk Of Magnesia-sus 400mg/5ml ... Milk Of Magnesia USP Sus 440mg/5ml ... Milk Of Magnesia Sus 440mg/5ml USP …
Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Synonyms: … Sodium acid carbonate ... Carbonic acid monosodium salt ... Sodio bicarbonato …
Matched Name: … Sodium bicarbonate …
Matched Iupac: … sodium hydrogen carbonate …
Matched Description: … replenisher, systemic alkalizer and in topical cleansing solutions. ... Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte …
Matched Mixtures name: … Juans Santo Remedio PARA LA ACIDEZ ... Omeprazole, Sodium Bicarbonate, Magnesium Hydroxide ... Omeprazole, Sodium Bicarbonate, Magnesium Hydroxide …
Matched Categories: … Antacids and Adsorbents ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Carbonic Acid ... Gastric Acid Lowering Agents …
Matched Products: … Arm and Hammer Baking Soda ... Sodium Bicarbonate ... SODIO BICARBONATO …
Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B.
Approved
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... coagulation factor IX, II, VII and X in combination …
Matched Products: … IMMUNINE 120IU/ML Powder and solvent for solution for injection or infusion …
Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the pancreas...
Approved
Matched Description: … Use of basal and bolus insulin together is intended to mimic the pancreas' production of endogenous insulin ... Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and ... into internal organs and tissues such as the liver, fat cells, and skeletal muscle. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Insulins and Analogues for Injection, Fast-Acting …
Matched Products: … Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 KwikPen …
Approved
Matched Synonyms: … Sus scrofa subcutaneous fat …
Panax notoginseng root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Investigational
Matched Synonyms: … Tienchi Ginseng (Constituent of American Ginseng, Asian Ginseng, and Tienchi Ginseng) …
Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis. Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain, or first line as a topical treatment of corticosteroid responsive dermatoses. Triamcinolone is more...
Approved
Vet approved
Matched Description: … Triamcinolone is more commonly seen in the forms triamcinolone hexacetonide, triamcinolone acetonide, and
Matched Mixtures name: … Nystatin and Triamcinolone ... Nystatin and Triamcinolone ... Nystatin and Triamcinolone …
Matched Categories: … Adrenals ... Medications that reduce magnesium levels ... Adrenal Cortex Hormones ... Alimentary Tract and Metabolism ... Sex Hormones and Insulins …
Matched Products: … Up and Up Nasal Allergy ... Foster and Thrive 24 Hour Nasal Allergy ... Aristospan Sus 20mg/ml …
A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Description: … It inhibits gastric acid secretion, as well as pepsin and gastrins output. …
Matched Mixtures name: … Cimetidine 10% / Lidocaine 5% / Salicylic Acid 40% ... Cimetidine 5% / Ibuprofen 2% / Salicylic Acid 17% …
Matched Categories: … Alimentary Tract and Metabolism ... Metabolic Side Effects of Drugs and Substances ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... Medications that reduce magnesium levels ... Acid Reducers …
Matched Products: … Up and Up Acid Reducer ... Cimetidine in Sodium Chloride ... Acid Reducer …
Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity.
Approved
Vet approved
Matched Description: … Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. ... [A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally ... [A192444] Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity. …
Matched Mixtures name: … Betamethasone Sodium Phosphate and Betamethasone Acetate ... Betamethasone Sodium Phosphate and Betamethasone Acetate ... Betamethasone Sodium Phosphate and Betamethasone Acetate
Matched Salts name: … Betamethasone acetate ... Betamethasone sodium phosphate …
Matched Categories: … Adrenals ... Adrenal Cortex Hormones ... Medications that reduce magnesium levels ... Alimentary Tract and Metabolism ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Betnesol Eye and Ear Drops ... Betnesol Eye and Ear Drops 0.1% ... BETAMETHASON ACIS CRINALE …
Vudalimab is under investigation in clinical trial NCT05005728 (Xmab®20717 (Vudalimab) Alone or in Combination With Chemotherapy or Targeted Therapy in Patients With Metastatic Castration-resistant Prostate Cancer).
Investigational
Matched Synonyms: … kappa/scfv-h-ch2-ch3, anti-(homo sapiens ctla4 (cytotoxic t-lymphocyte-associated protein 4, cd152)) and
Hydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension.[A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhibitors[L8390,L8423] or angiotensin II receptor blockers.[L7426,L7459] Hydrochlorothiazide was granted FDA...
Approved
Vet approved
Matched Description: … [A185138] It is indicated to treat edema and hypertension. ... [A185138] Many combination products are available containing hydrochlorothiazide and angiotensin converting …
Matched Mixtures name: … Co-Acetan - Tabletten ... Acetan HCT Tablet 100/25mg ... Acetan HCT Tablet 50/12.5mg …
Matched Categories: … Sodium Chloride Symporter Inhibitors ... Medications that reduce magnesium levels ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Matched Products: … Losartan Potassium and Hydrochlorothiazide …
Investigational
Matched Synonyms: … (L120>A,L121>E,G123>A,A216>S,P217>S)-TACI (TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR, TUMOR NECROSIS …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 326 - 350 of 3038 in total