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Displaying drugs 326 - 350 of 1622 in total
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED ON N.ALPHA..1ALANINE AND ... 356)-PEPTIDE, PRODUCED IN ESCHERICHIA COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND ... N6 OF LYSINE RESIDUES WITH …
Matched Description: … with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues ... as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Antineoplastic and Immunomodulating Agents …
Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison...
Approved
Investigational
Matched Description: … and bone fractures later in life. ... B12, and an increased risk of developing hypomagnesemia and hypocalcemia which may contribute to osteoporosis ... gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and
Matched Mixtures name: … Naproxen and esomeprazole magnesium ... Naproxen and esomeprazole magnesium ... Naproxen and Esomeprazole Magnesium …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Omeprazole and enantiomer ... naproxen and esomeprazole …
Matched Products: … NEXIUM 10MG GMR H SUSP EI ... Up and Up Esomeprazole Magnesium ... Berkley and Jensen Heartburn Treatment …
Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels of...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX, II, VII and X in combination ... Factor IX complex human ... Factor IX complex,human
Matched Name: … Factor IX Complex (Human) …
Matched Description: … Coagulation factors are purified from pooled human plasma and subsequently sterilized and treated. ... include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and ... For example, Kcentra (FDA) also contains the antithrombotic proteins C and S, while Bebulin VH (FDA) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid. It is a topical analgesic used for temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and bruises. Unlike other topical analgesics, trolamine...
Approved
Matched Description: … Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid ... temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and ... It also displays low systemic absorption upon dermal or topical administration [A32190] and has low skin …
Matched Products: … Up and Up Pain Relief Odorless ... Up and Up Odor-free Pain Relieving Cream …
Investigational
Matched Synonyms: … recombinant adeno-associated viral (AAV) vector that contains a bio-engineered capsid (AAV-Spark100) and ... a codon-optimized expression cassette to drive expression of a secretable form of human acid a-glucosidase …
Verpasep caltespen is a recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from Mycobacterium bovis, and the human papilloma viral (HPV) protein E7. Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be used to design vaccines against a...
Investigational
Matched Synonyms: … Recombinant fusion protein of Mycobacterium bovis BCG Hsp65 and HPV16 E7 ... Heat-shock protein HSP 65 (Mycobacterium BCG) fusion protein with transcription factor E7 (human papillomavirus …
Matched Description: … the human papilloma viral (HPV) protein E7. ... E7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen ... recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from _Mycobacterium bovis_, and
Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the levorotatory form (levopanthenol). While pantothenic acid is optically active, only the dextrorotatory...
Approved
Matched Description: … Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an ... Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the ... Due to its good penetration and high local concentrations, dexpanthanol is used in many topical products …
Matched Mixtures name: … Therapytion Nokmosu Sensitive and Dry Hair ... Therapytion Nokmosu Neutral and oily Hair …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … BABOR Baborganic Calm and Relax …
Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.[L7550,L7553,L7556,L7559,L7562,L7565]
Approved
Investigational
Nutraceutical
Matched Description: … vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and
Matched Mixtures name: … Multi-Vitamin Fluoride and Iron Drops ... Kordel"s Kid"s Multivitamins Plus Lysine Chewable Tablet ... Myhephron Dialysis and Stress Supplement …
Matched Categories: … Diet, Food, and Nutrition ... Nicotinic Acid and Derivatives ... lovastatin and nicotinic acid …
Matched Products: … JEUNCELL Hair restorer and Hair Growth Solution …
The chemical compound calcium acetate is the calcium salt of acetic acid. It has been commonly referred to as the acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form.
Approved
Investigational
Matched Synonyms: … Calcio acetato ... Calcium acetate ... calcium ethanoate …
Matched Name: … Calcium acetate …
Matched Iupac: … calcium diacetate …
Matched Description: … The chemical compound calcium acetate is the calcium salt of acetic acid. …
Matched Salts name: … Calcium acetate monohydrate …
Matched Categories: … calcium acetate and magnesium carbonate ... ascorbic acid (vit C) and calcium ... Alimentary Tract and Metabolism ... Phosphate Binder ... Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Products: … Calcium Acetate ... Calcium Acetate 667 mg ... Calcium Acetate Tab 667mg …
Afamitresgene autoleucel is a melanoma-associated antigen A4 (MAGE-A4)-directed genetically modified autologous T cell immunotherapy product consisting of CD4 and CD8 positive T cells transduced with a self-inactivating lentiviral vector (LV) expressing an affinity-enhanced T cell receptor (TCR) specific for the human MAGE-A4. MAGE-A4 is an intracellular cancer-testis antigen that is...
Approved
Investigational
Matched Synonyms: … AUTOLOGOUS CD4+ AND CD8+ T CELLS OBTAINED BY LEUKAPHERESIS, TRANSDUCED WITH AN HIV-DERIVED SELF-INACTIVATING ... (SIN) LENTIVIRAL VECTOR, ENCODING AN ENHANCED-AFFINITY T CELL RECEPTOR (TCR) SPECIFIC FOR THE HUMAN
Matched Description: … A4 (MAGE-A4)-directed genetically modified autologous T cell immunotherapy product consisting of CD4 and ... prepared from the patient’s peripheral blood mononuclear cells (PBMCs), which are enriched for T cells and ... [L51114] The transduced T cells are expanded, washed, formulated into a suspension, and cryopreserved …
Pacmilimab is under investigation in clinical trial NCT04596150 (Study to Evaluate the Safety and Antitumor Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer).
Investigational
Matched Synonyms: … ), DISULFIDE WITH PRODOMAIN PROTEIN (SYNTHETIC MASKING MOIETY AND CLEAVABLE MOIETY PROTEASE SUBSTRATE-CONTAINING ... IMMUNOGLOBULIN G4, ANTI-(HUMAN PROGRAMMED CELL DEATH-LIGAND 1) (HUMAN MONOCLONAL CX-072 .GAMMA.4-CHAIN ... ) FUSION PROTEIN WITH HUMAN MONOCLONAL C …
Matched Description: … Pacmilimab is under investigation in clinical trial NCT04596150 (Study to Evaluate the Safety and Antitumor ... Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer). …
Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be...
Approved
Investigational
Matched Description: … methionine before incorporation into DNA or protein. ... Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary ... activity, the two commercially available forms have been shown to be pharmacokinetically identical and
Matched Salts name: … Levoleucovorin calcium ... Levoleucovorin calcium pentahydrate …
Matched Categories: … Enzymes and Coenzymes ... Folic Acid and Derivatives ... calcium levofolinate ... Leucovorin Calcium-Levoleucovorin …
Matched Products: … Levoleucovorin Calcium ... CALCIO LEVOFOLINATO HOSPIRA ... CALCIO LEVOFOLINATO PENSA …
Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms. It is selective for the H1 receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier - this is in contrast to previous first-generation antihistamines, such as diphenhydramine, which readily bind to off-targets...
Approved
Investigational
Matched Description: … L4269] It is selective for the H1 receptor, carries little-to-no activity at off-targets, and ... [A1452] Fexofenadine is the major active metabolite of [terfenadine][A1495] and is administered as a …
Matched Mixtures name: … FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE ... FEXOFENADINE HCl AND PSEUDOEPHEDRINE HCl ... Allegra D 12 Hour Allergy and Congestion …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy Relief ... Up and Up Non Drowsy Allergy Relief …
Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. Due to its water solubility, ensulizole is commonly...
Approved
Matched Description: … It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter ... Due to its water solubility, ensulizole is commonly used in products formulated to feel light and less ... demonstrated by studies that ensulizole treatment provided protection against cyclobutane pyrimidine dimers and
Matched Mixtures name: … Advanced Firming and Anti Wrinkle ... LBEL Dermo Clarite Clarifying and Moisturizing with SPF 30 ... Advanced Firming and Anti Wrinkle …
Matched Products: … Dolce and Gabbana The Foundation Perfect Matte Broadspectrum SPF 20 All shades ... Lancome Paris Teint Idole Ultra Care and Glow Skincare Foundation Broad Spectrum SPF 27 Sunscreen …
Pectin is a heteropolysaccharide commercially derived from the cell wall of higher plants. It is composed of partially methylated polygalacturonic acid units linked in the positions 1-4. The carboxylic group of the constituents of pectin can exist in the form of esters, free acids, ammonium, potassium or sodium salts or...
Approved
Investigational
Vet approved
Matched Mixtures name: … Kaolin and Pectin Susp ... Cepacol Sore Throat and Coating ... Sucrets Complete Sore Throat, Cough and Irritation …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … Ludens Honey and Berry …
Tefidsogene civaparvovec, formerly known as SB-913, is an investigational therapy for genome editing. It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes. Developed by Sangamo...
Experimental
Matched Synonyms: … IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUS EXONS 2-9 FROM HIDS AND ... NON-REPLICATING ADENO-ASSOCIATED VIRUS TYPE 2/6 (RAAV REP2-CAP6) VECTOR, WHICH CONTAINS A PROMOTER-LESS HUMAN
Matched Description: … It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system …
Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Fusion protein consisting of il-15n72d and il-15rasu/fc ... Human interleukin 15 (72-aspartic acid) (human il-15 n72>d isoform) …
Matched Description: … 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG ... Nogapendekin alfa, in combination with inbakicept, mimics the actions of IL-15, , stimulating the activation and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Sus scrofa placenta is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Name: … Sus scrofa placenta …
Matched Description: … Sus scrofa placenta is an animal extract used in some OTC (over-the-counter) products. …
Wild boar hair is used in allergenic testing.
Approved
Matched Name: … Sus scrofa hair …
Matched Mixtures name: … Hog Hair and Epithelia …
Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class,...
Approved
Investigational
Vet approved
Matched Description: … Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults ... These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases ... This drug was the first clinical useful drug in its class, and its approval was followed by the formulation …
Matched Mixtures name: … Topcare Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate …
Matched Categories: … Alimentary Tract and Metabolism ... Omeprazole and enantiomer ... omeprazole, amoxicillin and rifabutin ... omeprazole, amoxicillin and clarithromycin ... omeprazole, amoxicillin and metronidazole …
Matched Products: … Up and Up Omeprazole ... Berkley and Jensen Omeprazole ... Foster and Thrive Omeprazole …
Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC ... ) transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene …
Matched Description: … Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing ... progenitor cells transduced _ex vivo_ using a lentiviral vector encoding the human arylsulfatase A ( …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78...
Approved
Matched Synonyms: … Recombinant human follicle stimulating hormone beta ... Recombinant human follicle-stimulating hormone (r-HFSH) …
Matched Description: … The alpha- and beta- subunits have 92 and 111 amino acids. ... 7 and Asn 24. ... assist in ovulation and fertility. …
Matched Mixtures name: … Pergoveris 150IU/75IU powder and solvent for solution for injection ... Pergoveris Powder and Solvent for Solution for Injection 150iu/75iu ... MENOGON 75 IU Powder and Solvent for solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … GONAL-F® 450 IU/0.75 ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... GONAL-F® 75 IU (5.5MCG) POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Aluminum zirconium tetrachlorohydrex gly is a common active ingredient in personal care products as an antiperspirant agent. Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.
Approved
Matched Description: … Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing …
Matched Products: … Ap 22% (regular,sport,musk and Unscented) ... Mitchum Clear Gel A.P. and Deod.supersport ... Body Satin Antiperspirant and Deodorant …
Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro­-25-(1-methylethyl)avermectin A1a (22,23-dihydroavermectin B1b). Ivermectin is mainly used in...
Approved
Investigational
Vet approved
Matched Description: … use for the prophylaxis and treatment of COVID-19. ... roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and ... against other worm infestations (such as strongyloidiasis, ascariasis, trichuriasis and enterobiasis …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides and Pediculicides …
Matched Products: … IVOMEC Injection 1% w/v for Cattle and Sheep ... Neck Hump Removal Patch …
Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that...
Approved
Matched Description: … Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and ... Due to its good penetration and high local concentrations, dexpanthanol is used in many topical products ... , such as ointments and lotions for treatment of dermatological conditions to relieve itching or promote …
Matched Mixtures name: … B Complex W C and B12 Inj ... Somarexin and C 1000 ... CH6 Perfumed Aloforthya Peony and the sunset …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Vitamin D and Analogues ... Preparations for Treatment of Wounds and Ulcers …
Matched Products: … Eros Aqua Sensations and Care Woman …
Displaying drugs 326 - 350 of 1622 in total