Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 351 - 375 of 421 in total

Bazlitoran

Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia).
Investigational
Matched Synonyms: … Antagonist of the endosomal Toll-like receptors (TLRs) 7, 8, and 9 …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Tirapazamine

Tirapazamine, also known as SR-4233, is an experimental anticancer drug that is activated in hypoxic conditions. This activation is very useful as this hypoxic state is found in human solid tumors in a common phenomenon known as tumor hypoxia. Hence, tirapazamine is solely activated in those hypoxic areas of solid...
Investigational
Matched Synonyms: … 1,2,4-benzotriazin-3-amine, 1,4-dioxide ... 3-Amino-1,2,4-benzotriazine 1,4-dioxide …
Matched Description: … Tirapazamine entered phase III testing in 2006 for patients with head and neck cancer and gynecological ... into consideration that normally, the cells in these hypoxic regions are resistant to radiotherapy and …

Etevritamab

Investigational
Matched Synonyms: … RECEPTOR, RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1, ERBB1, HER1, HER-1, ERBB) VARIANT III (EGFRVIII)) AND …

Silicon dioxide

Silicon dioxide, or silica, is an oxide of silicon with the chemical formula SiO2. It is found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite as transparent and tasteless crystals. Inhalation of fine crystals is toxic to humans leading to respiratory toxicity. In powdered food products...
Approved
Matched Synonyms: … Colloidal silicon dioxide ... Silicon dioxide, fumed ... Silicon dioxide, colloidal …
Matched Name: … Silicon dioxide …
Matched Description: … In powdered food products and pharmaceutical tablets, silicon dioxide is added as a flow agent to absorb ... as transparent and tasteless crystals. ... Colloidal silica is also used as a wine, beer, and juice fining agent or stabilizer. …
Matched Mixtures name: … Calcium and Magnesium 1:1 Plus Tablets ... Men's Biomultiple Vitamin and Mineral Supplement ... Women's Biomultiple Vitamin and Mineral Supplement …
Matched Products: … Chlorine Dioxide Air Sterilization Card …

Adenosine

The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Description: … L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole] and …
Matched Mixtures name: … Lip And Hand Wild Rose ... Lip And Hand Camellia ... Lip And Hand Shea Butter …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … rootree Treetherapy Rejuvenating Eye and Neck Treatment ... misoli Power Snail and Collagen Hydrog el Mask Pack …

Cimetidine

A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Description: … It inhibits gastric acid secretion, as well as pepsin and gastrins output. …
Matched Categories: … Alimentary Tract and Metabolism ... Metabolic Side Effects of Drugs and Substances ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Up and Up Acid Reducer …

Zirconium dioxide

Experimental
Matched Name: … Zirconium dioxide …

Cefotaxime

Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
Approved
Matched Description: … Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and ... In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. …
Matched Products: … Cefotaxime and Dextrose …

Sodium bicarbonate

Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Description: … powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and …
Matched Mixtures name: … PEG-3350 and Electrolytes ... Up and Up Antacid and Pain Relief ... HalfLytely and Bisacodyl …
Matched Categories: … Antacids and Adsorbents ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Arm and Hammer Baking Soda …

Flurbiprofen

Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Description: … Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen. ... Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and ... formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … Strepsils MaxPro Honey and Lemon lozenges 8.75mg …

Acazicolcept

Investigational
Matched Synonyms: … cell costimulator ligand variant immunoglobulin domain designed to inhibit simultaneously the CD28 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Aripiprazole

Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and...
Approved
Investigational
Matched Description: … [L45859] Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and antagonism ... of alpha-adrenergic and 5-HT2A receptors. ... treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and …
Matched Categories: … Aripiprazole and prodrugs …
Matched Products: … Abilify Maintena 400 mg powder and solvent for prolonged-release suspension for injection ... ABILIFY MAINTENA POWDER AND SOLVENT FOR PROLONGED RELEASE SUSPENSION FOR INJECTION 400 MG …

Pseudosaccharin chloride

Experimental
Matched Synonyms: … 3-Chlorobenzo(d)isothiazole 1,1-dioxide …

Ascorbic acid

A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic...
Approved
Nutraceutical
Matched Description: … Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and ... It is found naturally in citrus fruits and many vegetables. ... Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic …
Matched Mixtures name: … Multi Vitamin and Mineral vitamin ... Hvp Chelated Cal/mag With Zinc and Vitamins C and D ... Tri-Vitamin with iron and fluoride …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... Vitamin C and analogues ... Genito Urinary System and Sex Hormones ... ascorbic acid (vit C) and calcium …
Matched Products: … Sodium Ascorbate and Ascorbic Acid Pwr ... Vit.c With N-M.bioflav.rose Hips and Rutin ... Timed Release and Esterified Vitamin C-1000 …

Sulfur dioxide

Experimental
Matched Name: … Sulfur dioxide …

Cerium dioxide

Investigational
Matched Name: … Cerium dioxide …

Cyclothiazide

As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like cyclothiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter....
Approved
Matched Synonyms: … 6-chloro-3-(2-norbornen-5-yl)-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide ... 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide ... 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide …
Matched Description: … corticosteroid and estrogen therapy. ... tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and ... indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and …
Matched Categories: … Genito Urinary System and Sex Hormones ... cyclothiazide and potassium ... Gynecological Antiinfectives and Antiseptics …

Chlormezanone

A non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-(p-chlorphenyl)-3-methyl-1,3-perhydrothiazin-4-on-1,1-dioxide ... 2-(p-chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one 1,1-dioxide …
Matched Categories: … Oxazol, Thiazine, and Triazine Derivatives …

Somatrogon

Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Matched Synonyms: … .)-(118-145)-PEPTIDE (1-28) WITH HUMAN SOMATOTROPIN (GROWTH HORMONE, GH) (29-219) AND TWO TANDEM COPIES …
Matched Description: … adolescence and regulating metabolic function in adulthood. ... of somatrogon and allows its once-weekly dosing. ... by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Anterior Pituitary Lobe Hormones and Analogues ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists …

Ethylmorphine

A narcotic analgesic and antitussive. It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. It is not marketed in the US but is approved for use in various countries around the world. In the US it is a schedule II drug (single-entity) and...
Experimental
Illicit
Matched Synonyms: … Dionine …
Matched Description: … A narcotic analgesic and antitussive. ... It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function ... In the US it is a schedule II drug (single-entity) and schedule III drug (in combination products). …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives …

Docetaxel

Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Description: … Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of [paclitaxel]. ... chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and ... microtubulin with high affinity in a 1:1 stoichiometric ratio, allowing it to prevent cell division and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Oncotaxel Concentrate and solvent for solution for infusion 40 mg/ ml …

Sulbactam

Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus. When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.
Approved
Matched Synonyms: … Penicillanic acid 1,1-dioxide ... (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid 4,4-dioxide ... (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide …
Matched Description: … Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus. …
Matched Mixtures name: … Ampicillin and Sulbactam ... Ampicillin and Sulbactam ... Ampicillin and Sulbactam …

Acacia

Acacia allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Plants and plant parts, gum, acacia or arabic acacia senegal …

Benzthiazide

Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat...
Approved
Matched Synonyms: … 3-benzylthiomethyl-6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide ... 3-((benzylthio)methyl)-6-chloro-7-sulfamoyl-2H-benzo-1,2,4-thiadiazine 1,1-dioxide ... 3-benzylthiomethyl-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide …
Matched Description: … Benzthiazide is used to treat hypertension and edema. ... Thiazides also cause loss of potassium and an increase in serum uric acid. ... Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Diazoxide

Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels.[A255647,L44612] It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and does not have chloriuretic or natriuretic activity. Diazoxide is commonly used in the treatment of hyperinsulinaemic hypoglycemia due to its ability to inhibit insulin release....
Approved
Matched Synonyms: … 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide …
Matched Description: … [A255647] Diazoxide also exhibits hypotensive activity and reduces arteriolar smooth muscle and vascular ... and electrolyte disturbances. ... A255647,L44612] It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and …
Displaying drugs 351 - 375 of 421 in total