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Displaying drugs 351 - 375 of 15133 in total

Calcium phosphate dihydrate

Approved
Matched Mixtures name: … NAVI Black and C-Clinic …

Nifedipine

Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine.[A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972.[A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer...
Approved
Matched Description: … developed with slower onsets and longer durations of action. ... [A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature ... [A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been …
Matched Mixtures name: … Seaford Nifedipine and Lidocaine Hydrochloride Cream …
Matched Categories: … atenolol and nifedipine ... nifedipine and diuretics ... Calcium Channel Blockers and Diuretics ... Calcium-Regulating Hormones and Agents ... Beta blocking agents and calcium channel blockers …

Terbinafine

Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Description: … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …

Latanoprost

Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular pressure (IOP). It was initially approved by the FDA in 1998. Latanoprost is the first topical prostaglandin F2 alpha analog used for glaucoma treatment. It has been found to be well-tolerated and its use...
Approved
Investigational
Matched Description: … [A184493] It has been found to be well-tolerated and its use does not normally result in systemic adverse …
Matched Mixtures name: … Latanoprost and Timolol Ophthalmic Solution ... Latanoprost and Timolol STADA 50mcg/ml + 5mg/ml Eye drops ... LATANOPROST 0.05 MG/ML AND TIMOLOL 5 MG/ML SANDOZ EYE DROPS …
Matched Categories: … latanoprost and netarsudil ... Antiglaucoma Preparations and Miotics …

Moxidectin

Moxidectin is a potent, broad-spectrum endectocide (antiparasitic that is active against endo- and ecto-parasites) with activity against nematodes, insects, and acari. It was first used in cattle followed by an approved use in general animals. It is a semi-synthetic methoxine derivative of nemadectin which is a 16-member pentacyclic lactone of...
Approved
Investigational
Vet approved
Matched Description: … ) with activity against nematodes, insects, and acari. ... Moxidectin is a potent, broad-spectrum endectocide (antiparasitic that is active against endo- and ecto-parasites ... [A33385] Moxidectin was developed by Medicines Development for Global Health and FDA approved in June …
Matched Mixtures name: … Advocate Spot-on Solution for Small Cats and Ferrets …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …

Phenylpropanolamine

Phenylpropanolamine is a sympathomimetic agent that acts as a nonselective adrenergic receptor agonist and norepinephrine reuptake inhibitor. It has been used as a decongestant and appetite suppressant. Currently, it is withdrawn from the market in Canada and the United States due to the risk for hemorrahgic strokes.
Approved
Vet approved
Withdrawn
Matched Description: … It has been used as a decongestant and appetite suppressant. ... Phenylpropanolamine is a sympathomimetic agent that acts as a nonselective adrenergic receptor agonist and ... Currently, it is withdrawn from the market in Canada and the United States due to the risk for hemorrahgic …
Matched Mixtures name: … Counteract Sinus and Allergy ... Triaminic Cold and Allergy Syrup ... Contac Cough Cold and Flu Caplets …

Phylloquinone

Vitamin K1, also called phylloquinone or phytonadione, is a fat soluble vitamin.[L33319,L33345] Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates precursors to coagulation factors II, VII, IX, and X.[A234264,A234195,A234259] It is indicated in the treatment of coagulation disorders due to faulty formation of coagulation factors II,...
Approved
Investigational
Matched Description: … precursors to coagulation factors II, VII, IX, and X. ... [L33319,L33345] Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates ... the treatment of coagulation disorders due to faulty formation of coagulation factors II, VII, IX, and …
Matched Mixtures name: … Vitamin D2 and K1 ... NUTRILITE CHILDREN MULTIVITAMIN AND IRON CHEWABLE TABLET …
Matched Categories: … Diet, Food, and Nutrition ... Blood and Blood Forming Organs …

Progesterone

Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss . Progesterone is used in various contraceptive preparations to prevent ovulation...
Approved
Vet approved
Matched Description: … , embryo implantation, and the successful establishment of pregnancy. ... ], [A175612] as well as in other formulations to promote and support pregnancy. ... Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity …
Matched Mixtures name: … Estradiol and Progesterone …
Matched Categories: … progesterone and estrogen ... Progesterone and Derivatives ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Chlorzoxazone

A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
Approved
Matched Description: … is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and …
Matched Mixtures name: … Extra Strength Tylenol Aches and Strains …
Matched Categories: … Benzoxazoles and derivatives ... Oxazol, Thiazine, and Triazine Derivatives …

Ledipasvir

Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Matched Description: … and 3a of HCV. ... It is effective against genotypes 1a, 1b, 4a, and 5a and with a lesser activity against genotypes 2a ... count, and neuropsychiatric effects [A19635]. …
Matched Mixtures name: … Ledipasvir and Sofosbuvir …
Matched Categories: … sofosbuvir and ledipasvir …

Corynebacterium diphtheriae

Corynebacterium diphtheriae toxin is extracted from the pathogenic actinobacterium C. diphtheriae that causes diphtheria. The bacteria culture is grown in a medium and through purification, diphtheria toxin is detoxified with formaldehyde and diafiltered. The vaccine is intramuscularly administered to provide active immunization against diphtheria in infants and children.
Approved
Investigational
Matched Description: … formaldehyde and diafiltered. ... The bacteria culture is grown in a medium and through purification, diphtheria toxin is detoxified with ... vaccine is intramuscularly administered to provide active immunization against diphtheria in infants and …
Matched Mixtures name: … Tetanus and Diphtheria Toxoids Adsorbed …

Flutamide

An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Approved
Investigational
Matched Description: … An antiandrogen with about the same potency as cyproterone in rodent and canine species. …
Matched Categories: … Hormone Antagonists and Related Agents ... Antineoplastic and Immunomodulating Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Levonordefrin

Levonordefrin acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry.
Approved
Matched Description: … Levonordefrin acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry. …
Matched Mixtures name: … Mepivacaine Hydrochloride and Levonordefrin …
Matched Categories: … Epinephrine and similars …

Bordetella pertussis toxoid antigen (glutaraldehyde inactivated)

Approved
Investigational
Matched Mixtures name: … FILAMENTOUS HEMAGGLUTININ ANTIGEN (FORMALDEHYDE INACTIVATED), BORDETELLA PERTUSSIS PERTACTIN ANTIGEN, and …

Estradiol benzoate

Estradiol Benzoate is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol benzoate therefore has the same downstream...
Approved
Investigational
Vet approved
Matched Description: … a chance to enter systemic circulation and exert its estrogenic effects [A12102]. ... Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex ... same downstream effects within the body through binding to the Estrogen Receptor (ER) including ERα and …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Didecyldimethylammonium

Approved
Experimental
Matched Mixtures name: … SANIVIR Hands, Body, and Surfaces Sanitizer ... KLEANMANN - Hand Sanitizer and Surface Disinfectant …
Matched Categories: … Antiseptics and Disinfectants …

Fluoride ion

Having a chemical formula of F−, fluoride ion is the simplest inorganic, monatomic anion of fluorine with basic properties. It is considered a trace element. Fluoride ions are found in various minerals but are only present in trace amounts in water. Its various salt forms and minerals play numerous roles...
Approved
Matched Description: … Its various salt forms and minerals play numerous roles as chemical reagents, industrial chemicals, and ... It also plays an essential physiological role, such as enhancing the resistance profile and strength …
Matched Mixtures name: … Multi-Vitamin Fluoride and Iron Drops …

Dichlorobenzyl alcohol

Dichlorobenzyl alcohol is a mild antiseptic with a broad spectrum for bacterial and virus associated with mouth and throat infections. Dichlorobenzyl alcohol is considered as an active ingredient found in several marketed OTC products by Health Canada which has categorized this agent as an anatomical therapeutic chemical. On the other...
Approved
Matched Description: … with mouth and throat infections. ... Dichlorobenzyl alcohol is a mild antiseptic with a broad spectrum for bacterial and virus associated …
Matched Mixtures name: … STREPSILS HONEY AND LEMON ... STREPSILS SORE THROAT AND BLOCKED NOSE LOZENGE ... Difflam plus ANAESTHETIC Sore Throat Lozenges (Sugar Free) Menthol and Eucalyptus Flavour …

Fentanyl

Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] Fentanyl is related to other opioids like morphine and oxycodone. Fentanyl's high potency has also...
Approved
Illicit
Investigational
Vet approved
Matched Description: … Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia ... Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] Fentanyl is related to other opioids like [morphine] and …
Matched Categories: … Fentanyl and fentanyl analogues …

Fexinidazole

Human African trypanosomiasis (HAT, also colloquially referred to as sleeping sickness), caused by T. brucei gambiense and T. brucei rhodesiense, remains a moderate risk (>1/10,000 inhabitants per year in endemic areas) despite focussed control efforts. Transmitted by the bite of an infected tsetse fly, HAT is biphasic with a first...
Approved
Investigational
Matched Description: … trypanosomiasis (HAT, also colloquially referred to as sleeping sickness), caused by _T. brucei gambiense_ and ... [nifurtimox]/[eflornithine] combination therapy (NECT), though [melarsoprol] is highly toxic and each ... meningoencephalitic) stage in which patients experience progressively worsening neurological symptoms and …
Matched Categories: … Agents Against Leishmaniasis and Trypanosomiasis ... Antiparasitic Products, Insecticides and Repellents …

Fezolinetant

Vasomotor symptoms (VMS), more colloquially known as hot flashes or night sweats, are some of the most common symptoms in menopause. With a median duration of 7.4 years, vasomotor symptoms are also the most common reasons why women seek treatments for menopausal issues.[A259591,A259596] Although mostly considered a nuisance, vasomotor symptoms...
Approved
Investigational
Matched Description: … severe VMS daily have reported a decline in sleep quality, concentration, sexual activity, energy, and ... [A259606] Estrogen is a potent neuromodulator, particularly in the hypothalamus, and has been shown to ... increase neurokinin B signalling, increasing the activity of KNDy neurons and therefore the activity …
Matched Categories: … Genito Urinary System and Sex Hormones …

Calcitriol

Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D3, 1,25-dihydroxyvitamin D3. It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to DB00169 (vitamin D3)...
Approved
Nutraceutical
Matched Description: … In addition to promoting fatty acid synthesis and inhibiting lipolysis, calcitriol has been demonstrated ... There is also evidence that calcitriol modulates the action of cytokines and may regulate immune and ... chronic renal dialysis, and osteoporosis. …
Matched Categories: … Alimentary Tract and Metabolism ... Vitamin D and Analogues ... Diet, Food, and Nutrition ... Skin and Mucous Membrane Agents ... Calcium-Regulating Hormones and Agents …

Alfacalcidol

Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of vitamin D. It plays an essential function in calcium homeostasis and bone metabolism. Alfacaldisol is activated by the enzyme 25-hydroxylase in the liver to mediate its effects in the body, or most importantly, the kidneys and bones. The pharmacological...
Approved
Nutraceutical
Matched Description: … malabsorptive rickets and osteomalacia, vitamin D-dependent rickets and osteomalacia, and hypophosphataemic ... vitamin D resistant rickets and osteomalacia. ... [A234044] It plays an essential function in calcium homeostasis and bone metabolism. …
Matched Categories: … alendronic acid and alfacalcidol, sequential ... Vitamin D and Analogues ... Alimentary Tract and Metabolism ... Drugs Affecting Bone Structure and Mineralization …

Ferric subsulfate

Ferric subsulfate is a stypic or hemostatic agent that causes agglutination of surface proteins resulting in local hemostasis. It has the chemical formula Fe4(OH)2(SO4)5. It is used after superficial skin biopsies.
Approved
Experimental

Phthalylsulfathiazole

Phthalylsulfathiazole is a broad spectrum antibiotic which is part of the drug class, sulfonamides. It was used as an antibiotic for bowel surgery, and for infections of the colon .
Approved
Matched Iupac: … 2-({4-[(1,3-thiazol-2-yl)sulfamoyl]phenyl}carbamoyl)benzoic acid …
Matched Description: … It was used as an antibiotic for bowel surgery, and for infections of the colon [A175006]. …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Displaying drugs 351 - 375 of 15133 in total