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Displaying drugs 4201 - 4225 of 5627 in total
Gaboxadol also known as 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP) is an experimental sleep aid drug developed by Lundbeck and Merck, who reported increased deep sleep without the reinforcing effects of benzodiazepines. Development of Gaboxadol was stopped in March 2007 after concerns regarding safety and efficacy. It acts on the GABA system, but in...
Investigational
Matched Synonyms: … 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol …
Matched Iupac: … 2H,3H,4H,5H,6H,7H-[1,2]oxazolo[5,4-c]pyridin-3-one …
Matched Description: … aid drug developed by Lundbeck and Merck, who reported increased deep sleep without the reinforcing ... Development of Gaboxadol was stopped in March 2007 after concerns regarding safety and efficacy. ... It acts on the GABA system, but in a seemingly different way from benzodiazepines and other sedatives …
Investigational
Matched Synonyms: … 1-o-octadecyl-2-arachidonoyl-sn-glycerol-3-phosphoethanolamine …
Matched Iupac: … acid ... (2-aminoethoxy)[(2R)-2-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyloxy]-3-(octadecyloxy)propoxy]phosphinic …
A phosphodiesterase inhibitor with antidepressant properties.
Investigational
Matched Synonyms: … 4-(3-(Cyclopentyloxy)-4-methoxyphenyl)-2-pyrrolidinone …
Matched Iupac: … 4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one …
Epigallo Catechin Gallate is under investigation in clinical trial NCT00799890 (Sunphenon in Progressive Forms of Multiple Sclerosis).
Investigational
Matched Synonyms: … (+)-catechin 3-gallate …
Matched Iupac: … (2R,3S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate …
Fosmanogepix is under investigation in clinical trial NCT03604705 (An Efficacy and Safety Study of APX001 in Non-Neutropenic Patients With Candidemia).
Investigational
Matched Synonyms: … [2-amino-3-[3-[[4-(2-pyridyloxymethyl)phenyl]methyl]isoxazol-5-yl]pyridin-1-ium-1-yl]methyl hydrogen …
Matched Iupac: … 2-amino-1-[(hydrogen phosphonatooxy)methyl]-3-[3-({4-[(pyridin-2-yloxy)methyl]phenyl}methyl)-1,2-oxazol …
Matched Description: … Fosmanogepix is under investigation in clinical trial NCT03604705 (An Efficacy and Safety Study of APX001 …
Experimental
Matched Name: … 3-Amino-4-{3-[2-(2-Propoxy-Ethoxy)-Ethoxy]-Propylamino}-Cyclobut-3-Ene-1,2-Dione …
Matched Iupac: … 3-amino-4-(5,8,11-trioxa-1-azatetradecan-1-yl)cyclobut-3-ene-1,2-dione …
Experimental
Matched Name: … N-{4-METHYL-3-[(3-PYRIMIDIN-4-YLPYRIDIN-2-YL)AMINO]PHENYL}-3-(TRIFLUOROMETHYL)BENZAMIDE …
Matched Iupac: … N-(4-methyl-3-{[3-(pyrimidin-4-yl)pyridin-2-yl]amino}phenyl)-3-(trifluoromethyl)benzamide …
A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Approved
Investigational
Vet approved
Matched Synonyms: … (3H)-one ... (3H)-one ... 5-chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone …
Matched Iupac: … 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3 …
Matched Description: … It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool …
Matched Mixtures name: … DEXGARD 30/30 MG MR KAPSUL, 30 ADET ... DEXGARD 30/30 MG MR KAPSUL, 60 ADET ... DUEDOM 30/10 MG KAPSÜL, 30 ADET …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … DOMPERIDON BETA 10MG TABL ... MOTBIR 30 MG SR PELLET İÇEREN KAPSÜL, 30 ADET …
Thioproperazine is a potent neuroleptic with antipsychotic properties. Thioproperazine has a marked cataleptic and antiapomorphine activity associated with relatively slight sedative, hypothermic and spasmolytic effects. It is virtually without antiserotonin and hypotensive action and has no antihistaminic property. It is used for the treatment of all types of acute and...
Experimental
Matched Synonyms: … 2-dimethylsulfamido-(10-(3-1-methylpiperazinyl-4)propyl)-phenothiazine ... N,N-Dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine-2-sulfonamide ... (Thioproperazine)-2-dimethylsulfamido-(10-(3-1-methylpiperazinyl-4)propyl)-phenothiazine …
Matched Iupac: … N,N-dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine-2-sulfonamide …
Matched Description: … It is virtually without antiserotonin and hypotensive action and has no antihistaminic property. ... sedative, hypothermic and spasmolytic effects. ... Thioproperazine has a marked cataleptic and antiapomorphine activity associated with relatively slight …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Investigational
Matched Synonyms: … (5S,8S, 10aR)-N-benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo ... (3-METHYL-1-OXOBUTYL)-6-OXO-, (5S,8S,10AR)- ... 1,5)DIAZOCINE-8-CARBOXAMIDE, N-(DIPHENYLMETHYL)DECAHYDRO-5-(((2S)-2-(METHYLAMINO)-1-OXOPROPYL)AMINO)-3- …
Matched Iupac: … (5S,8S,10aR)-N-(diphenylmethyl)-5-[(2S)-2-(methylamino)propanamido]-3-(3-methylbutanoyl)-6-oxo-decahydropyrrolo …
GSK-269962A is a Rho kinase (ROCK) inhibitor with both ROCK1 and ROCK2 affinity.
Investigational
Matched Synonyms: … Benzamide, n-(3-((2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1h-imidazo(4,5-c)pyridin-6-yl)oxy)phenyl)- ... N-(3-((2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1h-imidazo(4,5-c)pyridin-6-yl)oxy)phenyl)-4-(2-(4-morpholinyl …
Matched Iupac: … N-(3-{[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy}phenyl)-4-[2-(morpholin …
Matched Description: … GSK-269962A is a Rho kinase (ROCK) inhibitor with both ROCK1 and ROCK2 affinity.[A253012] …
Experimental
Matched Name: … 2-Methyl-2-propanyl [(1R)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl]carbamate
Matched Iupac: … tert-butyl N-[(1R)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl]carbamate
Experimental
Matched Name: … 2-Amino-3-(1h-Indol-3-Yl)-Propan-1-Ol …
Matched Iupac: … (2S)-2-amino-3-(1H-indol-3-yl)propan-1-ol …
Experimental
Matched Name: … (3R)-3-[3,5-Bis(trifluoromethyl)anilino]-2-cyano-3-sulfanylpropanamide …
Matched Iupac: … 2-[(R)-{[3,5-bis(trifluoromethyl)phenyl]amino}(sulfanyl)methyl]-2-cyanoacetamide …
Experimental
Matched Name: … 6-[2-(3'-METHOXYBIPHENYL-3-YL)ETHYL]PYRIDIN-2-AMINE …
Matched Iupac: … 6-(2-{3'-methoxy-[1,1'-biphenyl]-3-yl}ethyl)pyridin-2-amine …
Experimental
Matched Name: … (5Z)-7-{(1R,4S,5R,6R)-6-[(1E)-1-Octen-1-yl]-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl}-5-heptenoic acid
Matched Iupac: … (5Z)-7-[(1R,4S,5R,6R)-6-[(1E)-oct-1-en-1-yl]-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl]hept-5-enoic acid
Investigational
Matched Synonyms: … 4-((4-(2-(6-((2r)-2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1h-tetrazol-1-yl)propyl)-3-pyridinyl ... )-3-pyridinyl)ethynyl)phenoxy)methyl)- ... Benzonitrile, 4-((4-(2-(6-((2r)-2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1h-tetrazol-1-yl)propyl …
Matched Iupac: … -3-yl}ethynyl)phenoxy]methyl}benzonitrile ... 4-{[4-(2-{6-[(2R)-2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1H-1,2,3,4-tetrazol-1-yl)propyl]pyridin …
CA-074 methyl ester (CA-074Me) is a cell-permeable cathepsin B inhibitor. It is converted by cellular esterases to CA-074.[A258234,A258239]
Experimental
Matched Synonyms: … (S)-methyl 1-((2S,3S)-3-methyl-2-((2S,3S)-3-(propylcarbamoyl)oxirane-2-carboxamido)pentanoyl)pyrrolidine ... Methyl (2S)-1-[(2S,3S)-3-methyl-2-[[(2S,3S)-3-(propylcarbamoyl)oxirane-2-carbonyl]amino]pentanoyl]pyrrolidine ... Methyl N-({(2s,3s)-3-[(propylamino)carbonyl]oxiran-2-Yl}carbonyl)-L-isoleucyl-L-prolinate …
Matched Iupac: … methyl (2S)-1-[(2S,3S)-3-methyl-2-{[(2S,3S)-3-(propylcarbamoyl)oxiran-2-yl]formamido}pentanoyl]pyrrolidine …
Matched Categories: … Amino Acids, Peptides, and Proteins
5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties. It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad. This drug, as well as dimethyltryptamine and bufotenin, have been registered to be used in South America in religious and spiritual rituals.
Experimental
Illicit
Matched Synonyms: … 3-(2-dimethylaminoethyl)-5-methoxyindole ... 3-[2-(N,N-Dimethylamino)ethyl]-5-methoxy-indole ... 5-methoxy-N,N-dimethyl-1H-indole-3-ethanamine …
Matched Iupac: … [2-(5-methoxy-1H-indol-3-yl)ethyl]dimethylamine …
Matched Description: … America in religious and spiritual rituals. ... It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado ... This drug, as well as [dimethyltryptamine] and [bufotenin], have been registered to be used in South …
Experimental
Matched Name: … (2S)-1-(1H-INDOL-3-YL)-3-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE …
Matched Iupac: … (2S)-1-(1H-indol-3-yl)-3-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]oxy}propan-2-amine …
Pramipexole is a drug used to treat the symptoms of Parkinson's Disease (PD). It is a non-ergot dopamine agonist drug that is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement) . It was first approved by the FDA in 1997 . Parkinson's Disease is...
Approved
Investigational
Matched Description: … agonist_ drug that is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and ... Parkinson's Disease is one of the most common neurodegenerative disorders and causes a high level of …
Matched Salts name: … Pramipexole hydrochloride
Matched Products: … PEXA XR 3 MG UZATILMIŞ SALIMLI TABLET, 30 ADET ... PEXOLA ER 3 MG UZATILMIS SALIMLI TABLET, 30 ADET ... PIDREX ER 3 MG UZATILMIŞ SALIMLI TABLET,TABLET, 30 ADET …
Hesperetin belongs to the flavanone class of flavonoids. Hesperetin, in the form of its glycoside hesperidin, is the predominant flavonoid in lemons and oranges.
Experimental
Matched Synonyms: … 3',5,7-Trihydroxy-4'-methoxyflavanone ... (S)-2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one …
Matched Iupac: … (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one …
Matched Description: … Hesperetin, in the form of its glycoside [hesperidin], is the predominant flavonoid in lemons and oranges …
Component of human seminal plasma & spermatozoa.
Experimental
Matched Synonyms: … Cholesterol 3-sulfate ... Cholesterol 3-sulphate …
Matched Iupac: … 8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl]oxidanesulfonic acid ... [(1R,3aS,3bS,7S,9aR,9bS,11aR)-9a,11a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-1H,2H,3H,3aH,3bH,4H,6H,7H, …
Stiripentol is an antiepileptic agent that is an aromatic allylic alcohol drug, which makes it structurally unique from other antiepileptic drugs.[A19740, A250825] The clinical development and marketing of stiripentol were first delayed due to the drug's potent inhibitory effects on hepatic cytochrome P450 (CYP) enzymes. However, its clinical efficacy as...
Approved
Matched Synonyms: … 4,4-Dimethyl-1-((3,4-methylenedioxy)phenyl)-1-penten-3-ol ... 1-(1,3-Benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-ol …
Matched Iupac: … (1E)-1-(2H-1,3-benzodioxol-5-yl)-4,4-dimethylpent-1-en-3-ol …
Matched Description: … [A19740, A250825] The clinical development and marketing of stiripentol were first delayed due to the ... [A19739] Approved in the US, Canada, and Europe, stiripentol is used to treat seizures associated …
Experimental
Matched Synonyms: … 7-Hydroxy-3-(4-hydroxyphenyl)-4-benzopyrone ... 7-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one …
Matched Iupac: … 7-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Displaying drugs 4201 - 4225 of 5627 in total