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Displaying drugs 401 - 425 of 2942 in total
Vudalimab is under investigation in clinical trial NCT05005728 (Xmab®20717 (Vudalimab) Alone or in Combination With Chemotherapy or Targeted Therapy in Patients With Metastatic Castration-resistant Prostate Cancer).
Investigational
Matched Synonyms: … kappa/scfv-h-ch2-ch3, anti-(homo sapiens ctla4 (cytotoxic t-lymphocyte-associated protein 4, cd152)) and
Hopantenic acid (Pantogam) is a central nervous system depressant. Hopantenic acid has a unique spectrum of pharmacological effects (nootropic, anticonvulsant, mild activating) in the absence of addiction, hyperstimulation or withdrawal syndrome.
Experimental
Matched Synonyms: … Acide hopantenique ... Acido hopantenico ... Hopantenic acid
Matched Name: … Hopantenic acid
Matched Iupac: … 4-[(2R)-2,4-dihydroxy-3,3-dimethylbutanamido]butanoic acid
Matched Description: … Hopantenic acid (Pantogam) is a central nervous system depressant. ... Hopantenic acid has a unique spectrum of pharmacological effects (nootropic, anticonvulsant, mild activating …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids
A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop...
Approved
Investigational
Matched Synonyms: … Etacrinic acid ... Etacrynic acid ... Acide étacrynique …
Matched Name: … Etacrynic acid
Matched Iupac: … 2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid
Matched Description: … Henle, but also in the proximal and distal tubules. ... A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of ... This pharmacological action results in excretion of these ions, increased urinary output, and reduction …
Matched Categories: … Acetates ... Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids ... etacrynic acid
Matched Products: … Ethacrynic Acid ... Ethacrynic acid
Cortisone acetate was first isolate in 1935 and became more widely researched in 1949. Since then, glucocorticoids such as cortisone acetate have been used to treat a number of inflammatory conditions such as endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, and gastrointestinal diseases and disorders.[A226300,L13203] Cortisone acetate...
Approved
Investigational
Matched Synonyms: … Cortone acetate ... Cortisone acetate ... Cortisone 21-acetate
Matched Name: … Cortisone acetate
Matched Iupac: … dioxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate
Matched Description: … Cortisone acetate was first isolate in 1935 and became more widely researched in 1949. ... gastrointestinal diseases and disorders. ... rheumatic, collagen, dermatologic, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, and
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Cortisone Acetate ... CORTISONE ACETATE ... CORTISONE ACETATO
Mycophenolic acid is a potent immunosuppressant agent that inhibits de novo purine biosynthesis. It was derived from Penicillium stoloniferum, and has also shown antibacterial, antifungal and antiviral properties. . Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus)...
Approved
Investigational
Matched Synonyms: … Acido micofenolico ... Acide mycophenolique ... Mycophenolic acid
Matched Name: … Mycophenolic acid
Matched Iupac: … (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
Matched Description: … [A249180] However, mycophenolic acid treatment is more expensive and requires therapeutic drug monitoring ... and antiviral properties. ... to optimize efficacy and minimize toxicity. …
Matched Categories: … Mycophenolic Acid and Prodrugs ... Antineoplastic and Immunomodulating Agents ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids
Matched Products: … Mycophenolic Acid ... Apo-mycophenolic Acid ... Mar-mycophenolic Acid
Phenylmercuric acetate is an organomercurial compound used as a fungicide and slimicide.
Investigational
Matched Synonyms: … (acetato)phenylmercury ... Phenylmercury acetate ... Phenyl mercuric acetate
Matched Name: … Phenylmercuric acetate
Matched Iupac: … phenylmercurio acetate
Matched Description: … Phenylmercuric acetate is an organomercurial compound used as a fungicide and slimicide.[A253082] …
Matched Salts name: … Phenylmercuric ammonium acetate
Investigational
Matched Synonyms: … (L120>A,L121>E,G123>A,A216>S,P217>S)-TACI (TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR, TUMOR NECROSIS …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Synonyms: … Heparinic acid
Matched Description: … coagulation enzymes thrombin (factor IIa) and factor Xa. ... UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. ... It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates …
Matched Mixtures name: … Heparin Sodium and Dextrose 5% Inj USP ... Heparin Sod and 0.9% Sod Chloride Inj …
Matched Categories: … Blood and Blood Forming Organs ... Heparin and similars …
Matched Products: … Heparin Sodium and Dextrose ... Heparin Sodium and Sodium Chloride …
Dehydroascorbic acid is made from the oxidation of ascorbic acid. This reaction is reversible, but dehydroascorbic acid can instead undergo irreversible hydrolysis to 2,3-diketogulonic acid. Dehydroascorbic acid as well as ascorbic acid are both termed Vitamin C, but the latter is the main form found in humans. In the body,...
Experimental
Matched Synonyms: … dehydro-L-ascorbic acid ... Oxidized ascorbic acid ... L-dehydroascorbic acid
Matched Name: … Dehydroascorbic acid
Matched Description: … In the body, both dehydroascorbic acid and ascorbic acid have similar biological activity as antivirals ... Dehydroascorbic acid is made from the oxidation of ascorbic acid. ... Dehydroascorbic acid as well as ascorbic acid are both termed Vitamin C, but the latter is the main form …
Matched Categories: … Diet, Food, and Nutrition ... Vitamin C and analogues ... Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids
Hydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension.[A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhibitors[L8390,L8423] or angiotensin II receptor blockers.[L7426,L7459] Hydrochlorothiazide was granted FDA...
Approved
Vet approved
Matched Description: … [A185138] It is indicated to treat edema and hypertension. ... [A185138] Many combination products are available containing hydrochlorothiazide and angiotensin converting …
Matched Mixtures name: … Co-Acetan - Tabletten ... Zinda-candesartan/hydrochlorothiazide ... Zinda-candesartan/hydrochlorothiazide …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... hydrochlorothiazide and potassium ... aliskiren and hydrochlorothiazide ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Matched Products: … Losartan Potassium and Hydrochlorothiazide …
An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Approved
Investigational
Matched Synonyms: … 6-Aminocaproic acid ... 6-aminohexanoic acid ... Acide aminocaproïque …
Matched Name: … Aminocaproic acid
Matched Iupac: … 6-aminohexanoic acid
Matched Mixtures name: … NAVI Black and C-Clinic ... Relief and Nature Toothpast E Jasmine Mint …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids
Matched Products: … Aminocaproic Acid ... Aminocaproic acid
Zinc citrate is a zinc salt of citric acid. It is available as dietary supplements as a treatment of zinc deficiency and source of zinc, which is an essential trace element. Zinc citrate demonstrates effective absorption following oral administration .
Investigational
Matched Synonyms: … Citric acid, zinc salt …
Matched Name: … Zinc citrate …
Matched Description: … It is available as dietary supplements as a treatment of zinc deficiency and source of zinc, which is ... Zinc citrate is a zinc salt of citric acid. ... Zinc citrate demonstrates effective absorption following oral administration [A27280]. …
Matched Mixtures name: … Calcium and Mag-potass and Zinc Cap ... Zinc and Vitamin C Lozenges ... Calcium, Magnesium, Zinc and D …
Matched Salts name: … Zinc citrate trihydrate …
Matched Categories: … Zinc Compounds …
Matched Products: … Zinc 50 mg ... Zinc Tab 15mg ... Zinc Citrate Tab 15mg …
Experimental
Matched Synonyms: … Hydroxydimethylarsine oxide ... Dimethylarsenic acid ... Dimethylarsinic acid
Matched Name: … Cacodylic acid
Matched Iupac: … dimethylarsinic acid
A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … Acidum citricum ... Anhydrous citric acid ... Citric acid,anhydrous …
Matched Name: … Citric acid
Matched Iupac: … 2-hydroxypropane-1,2,3-tricarboxylic acid
Matched Description: … It is an acid compound found in citrus fruits. ... [L14120] It is also used in combination with magnesium oxide to form magnesium citrate, an osmotic laxative ... The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability …
Matched Mixtures name: … Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid ... Sodium Citrate and Citric Acid ... Sodium Citrate and Citric Acid
Matched Salts name: … Citric acid monohydrate …
Matched Categories: … Alimentary Tract and Metabolism ... Acid Preparations ... Acids, Acyclic ... Carboxylic Acids ... citric acid
Matched Products: … Citric Acid ... Citric Acid Wipes …
Experimental
Matched Synonyms: … Acetic acid anion ... Acetic acid, ion(1-) ... Acetate
Matched Name: … Acetate
Matched Iupac: … acetate
Matched Categories: … Acetates ... Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Experimental
Matched Synonyms: … Ascorbic acid 2-O-glucoside …
Matched Name: … Ascorbyl glucoside …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Hydroxy Acids ... Carboxylic Acids
Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics.[A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as Pseudomonas aeruginosa, and is also indicated...
Approved
Investigational
Matched Description: … Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against ... [A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused ... by multi-resistant microorganisms such as _Pseudomonas aeruginosa_, and is also indicated for the empirical …
Matched Categories: … cefepime and amikacin …
Matched Products: … Cefepime Hydrochloride and Dextrose …
Experimental
Investigational
Matched Synonyms: … alpha-Tocopherol quinone ... alpha-Tocoquinone ... alpha-Tocopherolquinone …
Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins. It is further classified as a second-generation progestin, along with levonorgestrel and its derivatives, and is the active form of several other progestins including norethynodrel and lynestrenol. Norethisterone mimics the actions of endogenous...
Approved
Matched Description: … derivatives, and is the active form of several other progestins including [norethynodrel] and [lynestrenol ... endometriosis, and was not marketed for use as an oral contraceptive until 1962. ... [A10367] It is further classified as a second-generation progestin, along with [levonorgestrel] and its …
Matched Mixtures name: … Estradiol and Norethindrone Acetate ... Estradiol and Norethindrone Acetate ... Estradiol and Norethindrone Acetate
Matched Salts name: … Norethisterone acetate
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Combination Contraceptives (with Estrogen and derivatives) ... Sex Hormones and Insulins ... norethisterone and estrogen ... norethisterone and estrogen …
Matched Products: … LUTERON ... Norethindrone Acetate ... Norethindrone acetate
Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s.[A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with...
Approved
Vet approved
Matched Salts name: … Methylprednisolone acetate
Matched Categories: … Sex Hormones and Insulins ... methylprednisolone and antibiotics ... methylprednisolone and antiinfectives ... methylprednisolone and antiinfectives ... Ophthalmological and Otological Preparations …
Matched Products: … METHYLPREDNISOLON ACIS 4MG ... METHYLPREDNISOLON ACIS 8MG ... Methylprednisolone Acetate
Xaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman primate STEAP1 and CD3.
Investigational
Matched Synonyms: … STEAP family member 1, six transmembrane epithelial antigen of the prostate 1, STEAP1 metalloreductase) and
Matched Description: … primate STEAP1 and CD3. ... Xaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman …
Iocetamic acid is a diagnostic aid (radiopaque medium)
Approved
Matched Synonyms: … Acido iocetamico ... Iocetamic acid ... Acidum iocetamicum …
Matched Name: … Iocetamic acid
Matched Iupac: … 3-[N-(3-amino-2,4,6-triiodophenyl)acetamido]-2-methylpropanoic acid
Matched Description: … Iocetamic acid is a diagnostic aid (radiopaque medium) …
Matched Categories: … iocetamic acid
A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of...
Approved
Nutraceutical
Matched Synonyms: … Amber acid ... Acide succinique ... Acide butanedioïque …
Matched Name: … Succinic acid
Matched Iupac: … butanedioic acid
Matched Description: … A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine ... , the manufacture of lacquers, and to make perfume esters. ... It is also used in foods as a sequestrant, buffer, and a neutralizing agent. …
Matched Mixtures name: … Iron Fumarate and Aspartate, Glycinate, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium Threonate ... Iron Aspartate Glycinate and Polysaccharide Complex, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium ... Iron Aspartate, Glycinate, Ascorbic Calcium, Vitamin B12, Calcium Threonate and Succinic Acid
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids
Clodronic acid is a first generation bisphosphonate similar to etidronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. clodronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Investigational
Vet approved
Matched Synonyms: … Clodronic acid ... Acido clodronico ... Acide clodronique …
Matched Name: … Clodronic acid
Matched Iupac: … [dichloro(phosphono)methyl]phosphonic acid
Matched Description: … ], [ibandronic acid], [minodronic acid], and [risedronic acid]. ... Clodronic acid is a first generation bisphosphonate similar to [etidronic acid] and [tiludronic acid] ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... clodronic acid
Matched Products: … ACIDO CLODRONICO SANDOZ ... ACIDO CLODRONICO EG ... ACIDO CLODRONICO DOC GENERICI …
Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as ritonavir for the effective management of HIV-1 infection. As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006. Darunavir is being...
Approved
Matched Synonyms: … [(S)-3-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-2-hydroxy-1-((R)-phenylmethyl)-propyl]-carbamic acid ... {(1S,2R)-3-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-1-benzyl-2-hydroxy-propyl}-carbamic acid (3R,3aS …
Matched Description: … [A191682] Clinical trials are underway and are expected to conclude in August 2020.[L12066] …
Matched Categories: … Carboxylic Acids ... darunavir and cobicistat ... darunavir and ritonavir ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Darunavir 600 and 800 mg …
Displaying drugs 401 - 425 of 2942 in total