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Displaying drugs 451 - 475 of 635 in total

Tarlatamab

Tarlatamab is a first-in-class T-cell engager used to treat extensive-stage small cell lung cancer. It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed across various SCLC disease stages...
Approved
Investigational
Matched Synonyms: … Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens …
Matched Description: … across various SCLC disease stages and treatment statuses. ... L50748] It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and ... delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Water

Water (chemical formula: H2O) is a transparent fluid which forms the world's streams, lakes, oceans and rain, and is the major constituent of the fluids of organisms. As a chemical compound, a water molecule contains one oxygen and two hydrogen atoms that are connected by covalent bonds. Water is a...
Approved
Matched Description: … rain, and is the major constituent of the fluids of organisms. ... its solid state, ice; and gaseous state, steam (water vapor). ... Water (chemical formula: H2O) is a transparent fluid which forms the world's streams, lakes, oceans and …
Matched Mixtures name: … Medium Cuts and Scratches ... Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 Pieces ... SOLNARA Everything Blood circulation Nattokinase(Control blood pressure and Improve blood circulation …
Matched Products: … Salinaax Eye Wash and Skin Flush ... Aerowash Eyewash and Skin-Rinse ... Xpect First aid Buffered Eye and Skin …

Terbinafine

Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Description: … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues ... Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal. ... [A1279,A1281,L9068] Terbinafine hydrochloride was granted FDA approval on 30 December 1992. …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Salts name: … Terbinafine hydrochloride …
Matched Products: … Terbinafine Hydrochloride ... Terbinafine Hydochloride ... GoodSense Terbinafine Hydrochloride …

Chloroprocaine

Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride. Similar to other local anesthetics, it increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential. The pharmacological profile of...
Approved
Investigational
Matched Description: … Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride ... [A252952] Chloroprocaine can be given as an injection, and is available in formulations with and without ... formulation can be used for lumbar and caudal epidural blocks. …
Matched Salts name: … Chloroprocaine hydrochloride …
Matched Products: … Chloroprocaine Hydrochloride …

Lurasidone

Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Approved
Investigational
Matched Description: … Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently …
Matched Salts name: … Lurasidone hydrochloride …
Matched Products: … Lurasidone Hydrochloride ... Lurasidone hydrochloride …

Remifentanil

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Approved
Matched Description: … causes respiratory depression and analgesia. ... Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and ... a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and …
Matched Salts name: … Remifentanil hydrochloride …
Matched Categories: … Hypnotics and Sedatives ... Fentanyl and fentanyl analogues …
Matched Products: … Remifentanil Hydrochloride ... Remifentanil Hydrochloride for Injection …

Doxepin

Doxepin is a psychotropic agent with antidepressant and anxiolytic properties. It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer corresponding to cidoxepin. Doxepin commonly produces a 5:1 (E):(Z) racemic mixture. In a strict sense, doxepin is not a tricyclic antidepressant but...
Approved
Investigational
Matched Description: … Doxepin is a psychotropic agent with antidepressant and anxiolytic properties. ... [L5977] Doxepin was developed by Pfizer and FDA approved in 1969 as an antidepressant. ... [T559] It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer …
Matched Salts name: … Doxepin hydrochloride …
Matched Categories: … Hypnotics and Sedatives ... Antipruritics and Local Anesthetics ... Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Doxepin Hydrochloride ... Doxepin hydrochloride …

Clindamycin

Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris. It has a relatively narrow spectrum of activity that includes anaerobic bacteria as well as gram-positive cocci and bacilli and gram-negative bacilli. Interestingly,...
Approved
Vet approved
Matched Description: … bacilli and gram-negative bacilli. ... used off-label in the treatment of toxoplasmosis, malaria, and babesiosis. ... [A190621] Interestingly, clindamycin appears to carry some activity against protozoans, and has been …
Matched Mixtures name: … Clindamycin and Benzoyl Peroxide ... Clindamycin Phosphate and Tretinion ... Clindamycin and Benzoyl Peroxide …
Matched Salts name: … Clindamycin hydrochloride ... Clindamycin palmitate hydrochloride …
Matched Categories: … Genito Urinary System and Sex Hormones ... Macrolides, Lincosamides and Streptogramins ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Clindamycin Hydrochloride ... Clindamycin hydrochloride ... Cleocin Hydrochloride …

Oxybuprocaine

Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology. Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions.
Approved
Investigational
Matched Description: … Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and ... Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases …
Matched Mixtures name: … Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride …
Matched Salts name: … Oxybuprocaine hydrochloride …
Matched Products: … Minims Benoxinate Hydrochloride 0.4% …

Iodine

Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159]
Approved
Investigational
Matched Description: … Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may ... Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer. …
Matched Mixtures name: … Potassium and Iodine Tab ... Potassium and Iodine Tab ... Essential Vitamins and Minerals …
Matched Categories: … Diet, Food, and Nutrition ... Herbs and Natural Products ... Antiseptics and Disinfectants …
Matched Products: … XENETIX 300-50ML SOLN FOR INTRAVASCULAR, INTRAUTERINE AND INTRA-ARTICULAR INJ ... XENETIX 300-100ML SOLN FOR INTRAVASCULAR, INTRAUTERINE AND INTRA-ARTICULAR INJ …

Benzethonium

Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties. Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1-0.2 %, which are safe and effective concentrations for the compound specified by the U.S. Food and Drug Administration (FDA)....
Approved
Matched Description: … It is additionally found in cosmetics and toiletries such as mouthwashes and anti-itch ointments. ... Food and Drug Administration (FDA). ... Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum …
Matched Mixtures name: … Benzethonium Chloride and Dyclonine Hydrochloride ... Benzethonium chloride and Dyclonine hydrochloride ... Benzethonium Chloride and Dyclonine Hydrochloride …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … LYSOL Healthy Touch Cleansing Green Tea and Ginger ... Foaming Instant Hand Sanitizer with Aloe and Vitamin E ... Loesch Original Kleer-Plex Antimicrobial Face and Body Wash …

Granisetron

A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Approved
Investigational
Matched Description: … A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant …
Matched Salts name: … Granisetron hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants …
Matched Products: … Granisetron Hydrochloride ... Granisetron hydrochloride ... GRANISETRON HYDROCHLORIDE …

Minoxidil

A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Approved
Investigational
Matched Description: … potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and …
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Products: … Up and Up Minoxidil ... Up and Up minoxidil ... Berkley and Jensen Minoxidil …

Ciprofloxacin

Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Approved
Investigational
Matched Description: … [A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration …
Matched Mixtures name: … Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone …
Matched Salts name: … Ciprofloxacin hydrochloride …
Matched Categories: … ciprofloxacin and tinidazole ... ciprofloxacin and ornidazole ... ciprofloxacin and metronidazole ... Ophthalmological and Otological Preparations ... Drug-Related Side Effects and Adverse Reactions …
Matched Products: … Ciprofloxacin and Dextrose ... Ciprofloxacin hydrochloride ... Ciprofloxacin Hydrochloride …

Pyrethrum extract

Pyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. Pyrethrin refers to a more refined extract of pyrethrum. While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities. Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species....
Approved
Matched Synonyms: … Pyrethrins and pyrethroids …
Matched Description: … Pyrethrum extract is also used used to treat head, body, and pubic lice infections. ... The active compound is absorbed by the lice and destroys them by acting on their nervous systems but …
Matched Mixtures name: … Medi and Lice Lice Killing ... Lice-Nil Lice and Eggs Killer ... Weeks and Leo Complete Lice Treatment …

Acapatamab

Acapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (Mcrpc)).
Investigational
Matched Synonyms: … scfv-scfv-scfc, anti-(homo sapiens folh1 (folate hydrolase, prostate specific membrane antigen, psma)) and …
Matched Description: … Acapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for …

Lorigerlimab

Lorigerlimab is under investigation in clinical trial NCT05848011 (A Study of Lorigerlimab With Docetaxel or Docetaxel Alone in Participants With Metastatic Castration-resistant Prostate Cancer).
Investigational
Matched Synonyms: … ANTI-(HOMO SAPIENS CTLA4 (CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4, CD152)), CHIMERIC, HOMO SAPIENS AND ... MMUNOGLOBULIN G4 SCFV-H-CH2-CH3_SCFV, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD1, PD-1, CD279)) AND …

Nalbuphine

A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Approved
Matched Description: … It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid …
Matched Salts name: … Nalbuphine hydrochloride …
Matched Products: … Nalbuphine Hydrochloride …

Calcium carbonate

Calcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. Calcium carbonate may also...
Approved
Investigational
Matched Description: … It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. ... An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. …
Matched Mixtures name: … Mylanta Coat and Cool ... NAVI Black and C-Clinic ... Antacid and Anti-Gas Chew …
Matched Categories: … Antacids and Adsorbents ... Alimentary Tract and Metabolism ... ascorbic acid (vit C) and calcium …
Matched Products: … HEB Lime and Berry Antacid Chews ... Tums Chewy Bites Orange and Cream ES ... TopCare Lime and Berry Antacid Chews …

Methylcellulose

Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and emulsifier for foodstuffs and cosmetics. The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number of substituted hydroxyl groups per glucose with a theoretical maximum of 3,...
Approved
Matched Description: … emulsifier for foodstuffs and cosmetics. ... Like cellulose, it is not digestible, not toxic, and not allergenic ... Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Fiber Laxative 188 …

Thioridazine

A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed,...
Approved
Withdrawn
Matched Description: … A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the …
Matched Salts name: … Thioridazine hydrochloride …
Matched Products: … Thioridazine Hydrochloride …

Famotidine

Famotidine is a competitive histamine-2 (H2) receptor antagonist that works to inhibit gastric acid secretion. It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. Compared to other H2 receptor antagonists, famotidine displays high selectivity towards...
Approved
Matched Description: … gastroesophageal reflux disease (GERD), in adults and children. ... [A189462] Famotidine is used in various over-the-counter and off-label uses. ... It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and …
Matched Mixtures name: … Ibuprofen and famotidine ... Ibuprofen and Famotidine ... Ibuprofen and famotidine …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Up and Up Famotidine ... Berkley and Jensen Famotidine ... Berkley and Jensen Acid Controller …

Chlorpropamide

Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class...
Approved
Investigational
Matched International brands: … Glycemin …
Matched Description: … increase the number and sensitivity of insulin receptors. ... Renal and hepatic dysfunction may increase the risk of hypoglycemia. ... Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Pyridoxine

Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. While many plants and microorganisms are...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … and pyridoxamine 5'-phosphate. ... glycogen, the synthesis of nucleic acids, hemogloblin, sphingomyelin and other sphingolipids, and the ... As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required …
Matched Mixtures name: … Doxylamine succinate and pyridoxine hydrochloride ... Doxylamine succinate and pyridoxine hydrochloride ... Doxylamine Succinate and Pyridoxine Hydrochloride …
Matched Salts name: … Pyridoxine hydrochloride …
Matched Categories: … Diet, Food, and Nutrition ... Alimentary Tract and Metabolism ... isoniazid, sulfamethoxazole, trimethoprim and pyridoxine …
Matched Products: … Pyridoxine Hydrochloride ... Pyridoxine Hydrochloride Injection, USP ... Pyridoxine Hydrochloride Injection 100mg/ml …

Garcinia gummi-gutta fruit

Garcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Garcinia Cambogia (Constituent of Garcinia Cambogia and Garcinia Indica) …
Displaying drugs 451 - 475 of 635 in total