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Displaying drugs 451 - 475 of 8823 in total
Zeaxanthin
Zeaxanthin is a most common carotenoid alcohols found in nature that is involved in the xanthophyll cycle. As a coexistent isomer of lutein, zeaxanthin is synthesized in plants and some micro-organisms. It gives the distinct yellow color to many vegetables and other plants including paprika, corn, saffron and wolfberries. Zeaxanthin...
Approved
Investigational
Matched Iupac: … -tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl]-3,5,5-trimethylcyclohex-3-en-1-ol ... (1R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4R)-4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl]-3,7,12,16 …
Matched Description: … Zeaxanthin is one of the two primary xanthophyll carotenoids contained within the retina of the eye and ... As a coexistent isomer of lutein, zeaxanthin is synthesized in plants and some micro-organisms. ... It is available as a dietary supplement for eye health benefits and potential prevention of age-related …
Matched Description: … Zeaxanthin is one of the two primary xanthophyll carotenoids contained within the retina of the eye and ... As a coexistent isomer of lutein, zeaxanthin is synthesized in plants and some micro-organisms. ... It is available as a dietary supplement for eye health benefits and potential prevention of age-related …
Scorpion (centruroides) immune Fab2 antivenin (equine)
Centruroides (scorpion) Immune F(ab')2 (equine) is a purified preparation of immune globulin F(ab’)2 fragments that are derived from plasma of the horses immunized with venom of C. noxius, C. l. limpidus, C. l. tecomanus, and C. s. suffusus. It is intravenously administered patients with clinical signs of scorpion envenomation so...
Approved
Matched Description: … fragments that are derived from plasma of the horses immunized with venom of *C. noxius*, *C. l. limpidus ... Centruroides (scorpion) Immune F(ab')2 (equine) is a purified preparation of immune globulin F(ab’)2 ... It is intravenously administered patients with clinical signs of scorpion envenomation so that the Fab …
Talbutal
Talbutal, also called 5-allyl-5-sec-butylbarbituric acid, is a barbiturate with a short to intermediate duration of action. Talbutal is a schedule III drug in the U.S.
Approved
Illicit
Matched Iupac: … 5-(butan-2-yl)-5-(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione …
Matched Description: … also called 5-allyl-5-sec-butylbarbituric acid, is a barbiturate with a short to intermediate duration of …
Matched Description: … also called 5-allyl-5-sec-butylbarbituric acid, is a barbiturate with a short to intermediate duration of …
Hydroxocobalamin
Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency. It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia.
Approved
Matched Description: … Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B …
Matched Mixtures name: … ENJEKSİYONLUK ÇÖZELTİ, 100 AMPUL (50+50) …
Matched Mixtures name: … ENJEKSİYONLUK ÇÖZELTİ, 100 AMPUL (50+50) …
Imipenem
Imipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains.[label] It is stable to many beta-lactamases. Similar compounds include meropenem, known for having greater activity against Gram negative bacteria, and the newer ertapenem which exhibits...
Approved
Matched Description: … Imipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative …
Terbinafine
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Iupac: … [(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)[(naphthalen-1-yl)methyl]amine …
Matched Description: … inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of …
Matched Description: … inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of …
Bisacodyl
Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700]
Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Mixtures name: … PCP 100 Kit …
Mitapivat
Mitapivat is a novel, first-in-class pyruvate kinase activator. It works to increase the activity of erythrocyte pyruvate kinase, a key enzyme involved in the survival of red blood cells. Defects in the pyruvate kinase enzyme in various red blood cells disorders lead to the lack of energy production for red...
Approved
Investigational
Matched Description: … of red blood cells. ... It works to increase the activity of erythrocyte pyruvate kinase, a key enzyme involved in the survival ... Defects in the pyruvate kinase enzyme in various red blood cells disorders lead to the lack of energy …
Matched Categories: … combinations of sulfonamides …
Matched Categories: … combinations of sulfonamides …
Viloxazine
Viloxazine is a selective norepinephrine reuptake inhibitor. For decades, an immediate-release formulation of viloxazine has been used in Europe as an antidepressant. It was first approved in the UK in 1974; however, the immediate-release formulation was discontinued due to business reasons unrelated to drug safety and efficacy. In the US,...
Approved
Investigational
Withdrawn
Matched Description: … by the FDA for the treatment of attention deficit hyperactivity disorder (ADHD). ... In April 2021, an extended-release formulation of viloxazine under the brand name QELBREE was approved ... [L41685] For decades, an immediate-release formulation of viloxazine has been used in Europe as an antidepressant …
Sotalol
Sotalol is a methanesulfonanilide developed in 1960. It was the first of the class III anti arrhythmic drugs. Sotalol was first approved as an oral tablet on 30 October 1992. A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous injection indicated for life threatening...
Approved
Matched Description: … [A178579] It was the first of the class III anti arrhythmic drugs. ... [L6334] A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous …
Tiagabine
Tiagabine is an anti-convulsive medication. It is also used in the treatment for panic disorder as are a few other anticonvulsants. Though the exact mechanism by which tiagabine exerts its effect on the human body is unknown, it does appear to operate as a selective GABA reuptake inhibitor.
Approved
Investigational
Matched Iupac: … (3R)-1-[4,4-bis(3-methylthiophen-2-yl)but-3-en-1-yl]piperidine-3-carboxylic acid …
Phenylpropanolamine
Phenylpropanolamine is a sympathomimetic agent that acts as a nonselective adrenergic receptor agonist and norepinephrine reuptake inhibitor. It has been used as a decongestant and appetite suppressant. Currently, it is withdrawn from the market in Canada and the United States due to the risk for hemorrahgic strokes.
Approved
Vet approved
Withdrawn
Matched Mixtures name: … RHINOPRONT UZUN ETKILI 100 GR SUSPANSIYON ... RHINOTUSSAL UZUN ETKILI 100 GR SUSPANSIYON …
Japanese Encephalitis Vaccine, Inactivated, Adsorbed
Approved
Investigational
Nimodipine
Nimodipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Compared to other calcium channel blocking...
Approved
Investigational
Matched Description: … By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth …
Alprazolam
Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders.[L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ketoconazole and itraconazole.[L34783, L34788] Benzodiazepine treatment should be stopped gradually by tapering down a patient's dose to avoid withdrawal symptoms. Alprazolam's adverse...
Approved
Illicit
Investigational
Matched Description: … of the drug which may lead to coma and death. ... Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders. ... [A18125] Alprazolam has been mixed with alcohol as a drug of abuse to potentiate the sedative effects …
Matched Products: … XANAX 1 MG TABLET, 100 ADET …
Matched Products: … XANAX 1 MG TABLET, 100 ADET …
Fezolinetant
Vasomotor symptoms (VMS), more colloquially known as hot flashes or night sweats, are some of the most common symptoms in menopause. With a median duration of 7.4 years, vasomotor symptoms are also the most common reasons why women seek treatments for menopausal issues.[A259591,A259596] Although mostly considered a nuisance, vasomotor symptoms...
Approved
Investigational
Matched Description: … estrogen levels is thought to be the main cause of VMS, as estrogen therapy has been one of the most ... can thus induce the release of GnRH. ... the role of NK3R in the hypothalamic-pituitary-gonadal (HPG) axis. …
Parthenolide
Parthenolide has been used in trials studying the diagnostic of Allergic Contact Dermatitis.
Approved
Investigational
Matched Iupac: … (1S,2S,4R,7E,11S)-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.0^{2,4}]tetradec-7-en-13-one …
Matched Description: … Parthenolide has been used in trials studying the diagnostic of Allergic Contact Dermatitis. …
Matched Description: … Parthenolide has been used in trials studying the diagnostic of Allergic Contact Dermatitis. …
Viltolarsen
Duchenne muscular dystrophy (DMD) is an X-linked recessive allelic disorder characterized by a lack of functional dystrophin protein, which leads to progressive ambulatory, pulmonary, and cardiac function and is invariably fatal. A related, albeit a less severe, form of muscular dystrophy known as Becker muscular dystrophy (BMD) is characterized by...
Approved
Investigational
Matched Description: … restore partial muscle function and slow the progression of DMD. ... Duchenne muscular dystrophy (DMD) is an X-linked recessive allelic disorder characterized by a lack of ... is characterized by the production of shortened and partially functional dystrophin protein. …
Urokinase
Urokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and isoleucine 159 to yield active urokinase. Urokinase remains connected between these 2 chains by a sulfhydryl bond. Urokinase was granted FDA approval on 16 January 1978.
Approved
Investigational
Withdrawn
Matched Description: … Urokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and …
Paroxetine
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline...
Approved
Investigational
Matched Description: … It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic ... [A31914] Because of its potent inhibition of serotonin reuptake, paroxetine is more likely to cause withdrawal ... stress disorder, and symptoms of menopause, among others. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Flavin mononucleotide
A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues.
Approved
Investigational
Matched Description: … A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. …
Matched Mixtures name: … B-plex 100 ... Vitamin B Complex 100 …
Matched Mixtures name: … B-plex 100 ... Vitamin B Complex 100 …
Doxorubicin
Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Description: … [A1573,A257614,L45231] However, one of the major side effects of doxorubicin is cardiotoxicity, which ... Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius ... exert its effect through DNA intercalation, which eventually leads to DNA damage and the generation of …
Matched Products: … DOXORUBICIN INYECTABLE X 100 MG …
Matched Products: … DOXORUBICIN INYECTABLE X 100 MG …
Taurine
Taurine, whose chemical name is 2-aminoethanesulfonic acid, is one of the most abundant amino acids in several organs. It plays important role in essential biological processes. This conditional amino acid can be either be manufactured by the body or obtained in the diet mainly by the consumption of fish and...
Approved
Nutraceutical
Matched Description: … Taurine, whose chemical name is 2-aminoethanesulfonic acid, is one of the most abundant amino acids in ... amino acid can be either be manufactured by the body or obtained in the diet mainly by the consumption of …
Matched Mixtures name: … PEDASEL %10 AMİNO ASİT ÇÖZELTİSİ, 100 ML ... PRIMENE %10 İNFÜZYONLUK PEDİYATRİK AMİNOASİT ÇÖZELTİSİ, 100 ML …
Matched Mixtures name: … PEDASEL %10 AMİNO ASİT ÇÖZELTİSİ, 100 ML ... PRIMENE %10 İNFÜZYONLUK PEDİYATRİK AMİNOASİT ÇÖZELTİSİ, 100 ML …
Displaying drugs 451 - 475 of 8823 in total