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Displaying drugs 26 - 50 of 2310 in total

Cladribine

Cladribine is a purine analogue or a chlorinated derivative of adenine that causes apoptosis of B and T lymphocytes. Cladribine was first approved in the United States in 1993 initially as a treatment for a number of hematological malignancies; currently, it is approved for the treatment of hairy cell leukemia....
Approved
Investigational
Matched Synonyms: … 2-chloro-6-amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)purine ... (2R,3S,5R)-5-(6-amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol …
Matched Iupac: … (2R,3S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol …

Clobetasol propionate

Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. It has demonstrated superior activity compared to fluocinonide and was first described in the literature in 1974. Clobetasol Propionate was granted FDA approval on 27 December 1985.
Approved
Matched Synonyms: … 21-chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-propionate …

Betamethasone

Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity.
Approved
Vet approved
Matched Synonyms: … 9-Fluoro-16β-methylprednisolone …
Matched Salts cas: … 22298-29-9 …

Ciprocinonide

Approved
Investigational
Matched Synonyms: … .,9-difluoro-11.beta.,16.alpha.,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with ... 6α,9-Difluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone, …

Dextran

Dextran is a polysaccharide that differs from others in that its glucose units are joined together 1:6 glucoside links. The main chain of glucose has short branches at frequent intervals which are probably joined by 1:3 and 1:4 glucoside links. The chains can be composed of about 200,000 glucose units....
Approved
Investigational
Vet approved
Matched Mixtures name: … POLİFLEKS 60 MG/ML DEKSTRAN 70+9 MG/ML İZOTONİK SODYUM KLORÜR İV İNFÜZYON İÇİN ÇÖZELTİ, 500 ML PVC SETLI ... POLİFLEKS 60 MG/ML DEKSTRAN 70+9 MG/ML İZOTONİK SODYUM KLORÜR İV İNFÜZYON İÇİN ÇÖZELTİ, 1000 ML PVC SETLI ... POLİFLEKS 60 MG/ML DEKSTRAN 70+9 MG/ML İZOTONİK SODYUM KLORÜR İV İNFÜZYON İÇİN ÇÖZELTİ, 500 ML PVC SETSİZ …
Matched Products: … PF 60 MG/ML DEKSTRAN 70 9 MG/ML İZOTONİK SODYUM KLORÜR İV İNFÜZYON İÇİN ÇÖZELTİ, 1000 ML (CAM SISE) SETLI ... PF 60 MG/ML DEKSTRAN 70 9 MG/ML İZOTONİK SODYUM KLORÜR İV İNFÜZYON İÇİN ÇÖZELTİ, 500 ML (CAM SISE) SETLI ... PF 60 MG/ML DEKSTRAN 70 9 MG/ML İZOTONİK SODYUM KLORÜR İV İNFÜZYON İÇİN ÇÖZELTİ, 1000 ML (CAM SISE) SETSİZ …

Cangrelor

Cangrelor is an intravenous, direct-acting, reversible P2Y12 inhibitor for patients undergoing percutaneous coronary intervention (PCI) who have not been yet treated by oral P2Y12 inhibitors. An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel) is that it is an active drug not requiring metabolic conversion...
Approved
Matched Synonyms: … 2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(2-methylsulfanylethylamino)-2-(3,3,3-trifluoropropylsulfanyl)purin-9- …
Matched Iupac: … 5R)-3,4-dihydroxy-5-(6-{[2-(methylsulfanyl)ethyl]amino}-2-[(3,3,3-trifluoropropyl)sulfanyl]-9H-purin-9- …

Tretinoin

Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant,...
Approved
Investigational
Nutraceutical
Matched Synonyms: … (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid ... 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid (ECL) …
Matched Iupac: … (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid …
Matched Products: … AKNEVIT SOLÜSYON, 60 ML …

Sotorasib

Sotorasib, also known as AMG-510, is an acrylamide-derived KRAS inhibitor developed by Amgen.[A187547,A187556] It is indicated in the treatment of adult patients with KRAS G12C mutant non-small cell lung cancer. This mutation makes up >50% of all KRAS mutations. Mutant KRAS discovered in 1982 but was not considered a druggable...
Approved
Investigational
Matched Synonyms: … Kras G12C inhibitor 9 …

Procinonide

Approved
Investigational
Matched Synonyms: … .,9-difluoro-11.beta.,16.alpha.,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with …

Riboflavin

Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and...
Approved
Investigational
Nutraceutical
Vet approved
Matched Synonyms: … 6,7-Dimethyl-9-D-ribitylisoalloxazine …
Matched Mixtures name: … Protect Plus SO 60 ... MEGADYN PRONATAL FILM TABLET, 60 ADET ... ELEVIT PRONATAL FILM KAPLI TABLET, 60 ADET …

Gadopiclenol

Gadopiclenol is a gadolinium-based contrast agent (GBCA) based on a pyclen macrocyclic structure. It is indicated for use with magnetic resonance imaging (MRI) to detect and visualize lesions with abnormal vascularity in the central nervous system and the body. In 2006, the use of GBCAs was associated with the development...
Approved
Matched Synonyms: … (.alpha.3,.alpha.6,.alpha.9-tris(3-((2,3-dihydroxypropyl)amino)-3-oxopropyl)-3,6,9,15-tetraazabicyclo …

Repotrectinib

Repotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the ROS1 gene. ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation ROS1 G2032R is responsible for...
Approved
Investigational
Matched Synonyms: … 6S,)-45-FLUORO-3,6-DIMETHYL-5-OXA-2,8-DIAZA-1(5,3)-PYRAZOLO(1,5-A)PYRIMIDINA-4(1,2)-BENZENANONAPHAN-9- …
Matched Description: … defined oncogenic drives of NSCLC, and the solvent-front mutation ROS1 G2032R is responsible for 50 to 60% …

Methoxsalen

A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation.
Approved
Matched Synonyms: … 9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one …
Matched Iupac: … 9-methoxy-7H-furo[3,2-g]chromen-7-one …

Irinotecan

Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of camptothecin, which is extracted from the Chinese tree Camptotheca acuminate. The bis-piperidine side chain in the structure of irinotecan bestows enhanced water solubility. As an anticancer drug, irinotecan was first commercially available in Japan in 1994...
Approved
Investigational
Matched Synonyms: … 4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9- …
Matched Iupac: … hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21),2,4(9) …

Tiotropium

Tiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma.[A180163,L7084,L7087,L7090,L7093] Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation.[A180163,L7084,L7087,L7090,L7093] Tiotropium is more specific for the subset of muscarinic receptors commonly found in the...
Approved
Matched Iupac: … ^{2,4}]nonan-9-ium ... (1R,2R,4S,5S,7R)-7-{[2-hydroxy-2,2-bis(thiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.0 …
Matched Mixtures name: … FEROMIS 9/12 MCG INHALASYON TOZ ICEREN KAPSUL, 60 ADET ... SALTIF 9/50/100 MCG INHALASYON IÇIN TOZ IÇEREN BLISTER, 60 DOZ ... TIOBUD 9/200 MCG İNHALASYON İÇİN TOZ İÇEREN KAPSÜL, 60 ADET …
Matched Products: … TUTAST ARVOHALER 18 MCG İNHALASYON TOZU, 60 DOZ ... TIOFIX 18 MCG DISCAIR INHALASYON ICIN TOZ, 60 DOZ ... TIOTEK DİSCAİR 18 MCG İNHALASYON İÇİN TOZ, 60 DOZ …

Fluticasone propionate

Fluticasone propionate is a synthetic glucocorticoid[F4355,F4358][FDA Label]. These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications[F4355,F4358][FDA Label]. Fluticasone propionate was first approved in 1990 .
Approved
Matched Mixtures name: … SALTIF 9/50/100 MCG INHALASYON IÇIN TOZ IÇEREN BLISTER, 60 DOZ ... SALTIF 9/50/250 MCG INHALASYON IÇIN TOZ IÇEREN BLISTER, 60 DOZ ... SALTIF 9/50/500 MCG INHALASYON IÇIN TOZ IÇEREN BLISTER, 60 DOZ …
Matched Products: … FLIXOTIDE DISKUS 50 MCG, 60 DOZ ... FLIXOTIDE INHALER 50 MG, 60 DOZ ... FLIXOTIDE INHALER 25 MCG, 60 DOZ …

Paclitaxel

Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel. It is available as...
Approved
Vet approved
Matched Synonyms: … 5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate …

Folic acid

Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis. More specifically, folic acid is required by the body for the synthesis of purines, pyrimidines, and methionine before incorporation into DNA...
Approved
Nutraceutical
Vet approved
Matched Mixtures name: … Mvc 9+4 Inj ... Mvc 9 Plus 3 Inj ... Protect Plus SO 60 …
Matched Products: … FOLIB-9 ACIDO FOLICO 5 MG TABLETAS ... FOLIB - 9 (ACIDO FOLICO 1 MG TABLETAS) …

Etoricoxib

Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic...
Approved
Investigational
Matched Description: … It is approved in more than 60 countries worldwide but not in the US. …
Matched Products: … Etrobax 60 (Etoricoxib Tablets 60 mg) ... ETROBAX 60 FILM COATED TABLETS 60 MG ... SIKSTOP 60 …

Biotin

A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Approved
Investigational
Nutraceutical
Matched Mixtures name: … Mvc 9+4 Inj ... Mvc 9 Plus 3 Inj ... Protect Plus SO 60 …
Matched Products: … HIOTIN 5 MG TABLET,TABLET, 60 ADET ... BIOAK 5MG TABLET ,TABLET, 60 ADET …

Ticagrelor

Ticagrelor, or AZD6140, was first described in the literature in 2003.[A204170,A2903] Ticagrelor is an ADP derivative developed for its P2Y12 receptor antagonism. Unlike clopidogrel, ticagrelor is not a prodrug. It is marketed by Astra Zeneca as Brilinta in the US and Brilique or Possia in the EU, . Ticagrelor was...
Approved
Matched Products: … TICAGREL 60 ... BRILINTA® 60 MG ... BRILINTA TABLET 60 MG …

Duloxetine

Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder. It has since received approval for a...
Approved
Matched Salts cas: … 136434-34-9 …
Matched Products: … DULOXTA 60 ... ALACIR® 60 ... CYMBALTA (60 MG) …

Cinacalcet

Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe. It is used to treat hyperparathyroidism due to parathyroid tumours or renal failure.
Approved
Matched Products: … CETCAL® 60 ... MIMPARA® 60 MG ... CINACRED 60 MG TABLETAS …

Diltiazem

Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle...
Approved
Investigational
Matched Products: … CARDIUM 60 TABLET 60 mg ... HERBESSER 60 TABLET 60 mg ... DILKOR SR 60 MG MİKROPELLET KAPSÜL, 60 ADET …

Diatrizoate

A commonly used x-ray contrast medium. As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Approved
Vet approved
Matched Mixtures name: … Md-60 ... Md-60 ... Renografin-60 …
Matched Products: … Reno-60 ... Reno-M-60 ... Hypaque-M 60% …
Displaying drugs 26 - 50 of 2310 in total