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Displaying drugs 26 - 50 of 1338 in total
A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues.
Approved
Investigational
Matched Synonyms: … Riboflavin phosphate ... riboflavin 5'-phosphate ... Vitamin B2 phosphate
Matched Salts name: … Riboflavin sodium phosphate ... Riboflavin 5'-phosphate sodium anhydrous ... Riboflavin-5'-phosphate sodium salt dihydrate …
Kappadione is a Vitamin K derivative (chemically, it is menadiol sodium diphosphate), previously approved by FDA prior to 1982 and marketed by Lilly Marketing for this drug has been discontinued and is not available in North America . It has been found to have carcinogenic potential in mammalian cells as...
Approved
Matched Synonyms: … Menadiol sodium diphosphate …
Matched Iupac: … tetrasodium 3-methyl-4-(phosphonatooxy)naphthalen-1-yl phosphate
Matched Description: … Kappadione is a Vitamin K derivative (chemically, it is menadiol sodium diphosphate), previously approved …
Approved
Experimental
Matched Synonyms: … Ferric glyceryl phosphate
Miltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid drug that was originally developed in the 1980s as an anti-cancer agent. It is currently the only recognized oral agent used to treat visceral, cutaneous, and mucosal forms of leishmaniasis, a neglected tropical disease. It can be administered topically or orally and...
Approved
Investigational
Matched Synonyms: … hexadecyl 2-(trimethylazaniumyl)ethyl phosphate
Matched Iupac: … hexadecyl 2-(trimethylazaniumyl)ethyl phosphate
Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in GAA. Other types of enzyme replacement therapy for the treatment of Pompe disease include alglucosidase alfa and avalglucosidase alfa. Cipaglucosidase...
Approved
Investigational
Matched Synonyms: … Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphate
Matched Description: … mannose-6-phosphate receptor (CI-MPR) in skeletal muscle, one of the main affected tissues in Pompe ... Cipaglucosidase alfa is conjugated with mannose-6-phosphate (M6P) N-glycans that bind to the cation-independent …
Sodium cellulose phosphate is used to treat hypercalcemia and hypercalciuria. It has been used to prevent kidney stones. This compound is an ion-exchange resin that can not be absorbed by the body. However, it can be used to restore normal intestinal calcium absorption.
Approved
Matched Synonyms: … Cellulose sodium phosphate ... Cellulose disodium phosphate ... Cellulose dihydrogen phosphate, disodium salt …
Matched Name: … Sodium cellulose phosphate
Matched Description: … Sodium cellulose phosphate is used to treat hypercalcemia and hypercalciuria. ... However, it can be used to restore normal intestinal calcium absorption. …
Matched Categories: … sodium cellulose phosphate ... Calcium Binder ... Calcium Chelating Activity …
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
Approved
Vet approved
Matched Synonyms: … 6-chloro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
Matched Salts name: … Chlorothiazide sodium
Matched Categories: … Sodium Chloride Symporter Inhibitors …
Matched Products: … DIURIL Sodium ... Sodium Diuril ... Chlorothiazide Sodium
Approved
Matched Synonyms: … Sodium phosphate 32P ... Sodium phosphate (32P) ... Sodium phosphate P 32 …
Matched Name: … Sodium phosphate P 32 …
Matched Iupac: … disodium hydrogen (32P)phosphate
Matched Categories: … sodium phosphate (32P) …
Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919. For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats....
Approved
Nutraceutical
Vet approved
Matched Description: … pantoic acid and β-alanine and commonly found as its alcohol analog, the provitamin panthenol, and as calcium
Matched Salts name: … Calcium pantothenate ... Sodium pantothenate …
Matched Categories: … calcium pantothenate ... calcium pantothenate …
Matched Products: … Calcium Pantothenate Tab 250mg …
An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Approved
Matched Salts name: … Fenoprofen calcium ... Fenoprofen sodium
Matched Products: … Fenoprofen Calcium
Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Description: … Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal …
Matched Salts name: … Sevelamer carbonate
Matched Categories: … Phosphate Binder ... Phosphate-removing Agents ... Phosphate Chelating Activity …
Matched Products: … Sevelamer carbonate ... Sevelamer Carbonate ... Sevelamer Carbonate Zentiva …
A depressor amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
Approved
Investigational
Matched Salts name: … Histamine phosphate
Matched Categories: … histamine phosphate
Matched Products: … Histamine Phosphate Injection USP Liq Sc ... Histamine Phosphate Injection USP, 1mg/ml …
Phosphoric Acid is a colorless, odorless phosphorus-containing inorganic acid. Phosphoric acid is a sequestering agent which binds many divalent cations, including Fe++, Cu++, Ca++, and Mg++.
Approved
Matched Mixtures name: … Denti-care Acidulated Phosphate Fluoride …
Oseltamivir (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. Oseltamivir exerts its antiviral activity by inhibiting the activity of the viral neuraminidase enzyme found on the surface of the virus, which...
Approved
Matched Salts name: … Oseltamivir phosphate
Matched Products: … Oseltamivir Phosphate ... Oseltamavir Phosphate ... Oseltamivir phosphate
Potassium citrate (also known as tripotassium citrate) is a potassium salt of citric acid. It is a white, hygroscopic crystalline powder. It is odorless with a saline taste. It contains 38.3% potassium by mass. In the monohydrate form it is highly hygroscopic and deliquescent. Potassium citrate is used to treat...
Approved
Investigational
Vet approved
Matched Description: … Potassium Citrate is indicated also for the management of Hypocitraturic calcium oxalate nephrolithiasis …
Matched Mixtures name: … Calcium and Mag-potass and Zinc Cap ... Calcium-magnesium With K & Zn and Vitamin D3 ... Potassium Citrate-Sodium Citrate-Citric Acid …
Ergocalciferol is an inactivated vitamin D analog. It is synthesized by some plants in the presence of UVB light. The production of ergocalciferol was prompted by the identification of dietary deficiency, more specifically vitamin D, as the main causative factor for the development of rickets. Ergocalciferol was isolated for the...
Approved
Nutraceutical
Matched Mixtures name: … Calcium With Vitamin D2 ... Calcium Chelate Plus Vit D ... SAFWA HEALTH CALCIUM AND VITAMIN D …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Matched Description: … Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus …
Matched Mixtures name: … Oyster Shell Calcium ... Oyster Shell Calcium with Vitamin D ... Oyster Shell Calcium with Vitamin D …
Matched Categories: … Calcium-Regulating Hormones and Agents ... zoledronic acid, calcium and colecalciferol, sequential ... alendronic acid, calcium and colecalciferol, sequential ... risedronic acid, calcium and colecalciferol, sequential …
Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of vitamin D. It plays an essential function in calcium homeostasis and bone metabolism. Alfacaldisol is activated by the enzyme 25-hydroxylase in the liver to mediate its effects in the body, or most importantly, the kidneys and bones. The pharmacological...
Approved
Nutraceutical
Matched Description: … [A234044] It plays an essential function in calcium homeostasis and bone metabolism. …
A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
Approved
Matched Salts name: … Disopyramide phosphate
Matched Categories: … Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …
Matched Products: … Disopyramide Phosphate ... Disopyramide Phosphate ER …
Burosumab (KRN23) is an entirely human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic rickets . The U.S. Food and Drug Administration approved Crysvita (burosumab) in April 2018. This is the first drug approved...
Approved
Investigational
Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis. Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism (HPT) in adult patients with chronic kidney disease (CKD) on hemodialysis in February, 2017.
Approved
Investigational
Matched Categories: … Calcium Homeostasis ... Calcium-sensing Receptor Agonist ... Increased Calcium-sensing Receptor Sensitivity …
Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of a...
Approved
Investigational
Vet approved
Matched Salts name: … Chloroquine phosphate
Matched Products: … Chloroquine Phosphate ... Chloroquine phosphate ... CHLOROQUINE PHOSPHATE
Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. Felodipine is the most potent CCB...
Approved
Investigational
Matched Description: … By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte ... In addition to binding to L-type calcium channels, felodipine binds to a number of calcium-binding proteins ... influx through voltage-gated T-type calcium channels. …
Matched Categories: … Calcium Channel Blockers ... ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers (Dihydropyridine) ... Beta blocking agents and calcium channel blockers …
Nimodipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Compared to other calcium channel blocking...
Approved
Investigational
Matched Description: … By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth ... Nimodipine is a 1,4-dihydropyridine calcium channel blocker. ... It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels …
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers (Dihydropyridine) ... Selective Calcium Channel Blockers With Mainly Vascular Effects …
Nisoldipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nisoldipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Nisoldipine may be used in alone...
Approved
Matched Description: … By inhibiting the influx of calcium in smooth muscle cells, nisoldipine prevents calcium-dependent smooth ... Nisoldipine is a 1,4-dihydropyridine calcium channel blocker. ... It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels …
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers (Dihydropyridine) ... Selective Calcium Channel Blockers With Mainly Vascular Effects …
Displaying drugs 26 - 50 of 1338 in total