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Displaying drugs 26 - 50 of 8504 in total
Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label]. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons. The amino acid sequence of the product is identical to that of endogenous human IGF-1. The rhIGF-1 protein is...
Approved
Investigational
Matched Synonyms: … VEXXON-IGF-1 ... INSULIN-LIKE GROWTH FACTOR 1 ... INSULIN-LIKE GROWTH FACTOR I (HUMAN) …
Matched Description: … gene for human IGF-1. ... Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label ... The amino acid sequence of the product is identical to that of endogenous human IGF-1. …
Matched Categories: … Recombinant Human Insulin-like Growth Factor-1
An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
Approved
Investigational
Matched Synonyms: … 2,3-Dimethyl-1-phenyl-5-pyrazolone ... 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one …
Matched Iupac: … 1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one …
Matched Mixtures name: … SUPRENIL STERIL OFTALMIK SUSPANSIYON 5 ML …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … TROPEX EAR DROPS 5% w/v …
Cerliponase alfa is an enzyme replacement treatment for a specific form of Batten disease. It was the first FDA-approved treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and older with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl...
Approved
Investigational
Matched Synonyms: … Immature tripeptidyl-peptidase I ... Immature human tripeptidyl-peptidase 1 ... Immature cell growth-inhibiting gene 1 protein …
Matched Description: … with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl peptidase-1
Dasabuvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Matched Synonyms: … Sodium 3-(3-tert-butyl-4-methoxy-5-{6­ [(methylsulfonyl)amino]naphthalene-2-yl}phenyl)-2,6-dioxo-3,6 ... N-{6-[3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl]naphthalen-2-yl}methanesulfonamide ... -dihydro-2H-pyrimidin-1-ide hydrate (1:1:1) …
Matched Iupac: … N-{6-[3-tert-butyl-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-2-methoxyphenyl]naphthalen-2-yl}methanesulfonamide …
Matched Description: … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... are poorly conserved across HCV genotypes leading to the restriction of Dasabuvir's use to genotype 1
Matched Salts name: … Dasabuvir sodium ... Dasabuvir sodium monohydrate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle...
Approved
Investigational
Matched Synonyms: … (+)-cis-5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H) ... (2S-cis)-3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin- ... (2S,3S)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin …
Matched Iupac: … (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3- …
Matched Salts cas: … 33286-22-5
Matched Products: … FARMABES 5 ... DILTIAZEM 25 MG/5 ML SOLUCIÓN INYECTABLE - 1D1003281000 ... TİACARD 25MG ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 ADET …
Repotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the ROS1 gene. ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation ROS1 G2032R is responsible for...
Approved
Investigational
Matched Synonyms: … (3R,6S,)-45-FLUORO-3,6-DIMETHYL-5-OXA-2,8-DIAZA-1(5,3)-PYRAZOLO(1,5-A)PYRIMIDINA-4(1,2)-BENZENANONAPHAN …
Matched Iupac: … 11S)-6-fluoro-3,11-dimethyl-10-oxa-2,13,17,18,21-pentaazatetracyclo[13.5.2.0^{4,9}.0^{18,22}]docosa-1( …
Matched Description: … This approval is based on favorable results from the TRIDENT-1 study, where the objective response rate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Il-15n72d:il-15rec-su/fc soluble complex i
The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor to all-cause mortality is hypertension. Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. Treatment for hypertension should include a number of lifestyle changes (ie. reduced...
Approved
Matched Iupac: … 4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-sulfamoylbenzamide …
Matched Description: … [A204155] Treatment for hypertension should include a number of lifestyle changes (ie. reduced sodium
Matched Mixtures name: … Fludexam 1,5 mg/5 mg Tabletten mit veränderter Wirkstofffreisetzung ... Fludexam 1,5 mg/10 mg Tabletten mit veränderter Wirkstofffreisetzung ... Triplixam 5 mg/1,25 mg/5 mg Filmtabletten …
Matched Categories: … Sodium Chloride Symporter Inhibitors …
Matched Products: … FLUDEX Retard 1,5 mg - Filmtabletten ... FLUPAMID 1,5 MG SR TABLET, 30 TABLET ... Indapamid Krka 1,5 mg Retardtabletten …
Human interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of natural human interferon beta.
Approved
Investigational
Matched Synonyms: … Interferon beta 1-a …
Matched Categories: … Interferon Type I
Matched Products: … REBİF 66 MCG/ 1,5 ML KARTUŞTA ENJEKSİYONLUK ÇÖZELTİ, 4 ADET ... REBİF 132 MCG/ 1,5 ML KARTUŞTA ENJEKSİYONLUK ÇÖZELTİ, 4 ADET ... REBİF 66 MCG/ 1,5 ML KARTUŞTA ENJEKSİYONLUK ÇÖZELTİ, 12 ADET …
Cariprazine is an atypical antipsychotic agent and a piperazine derivative that was first developed in Hungary. It works as a partial agonist at central dopamine D2, dopamine D3, and serotonin 5-HT1A receptors and as an antagonist at serotonin 5-HT2A receptors. Cariprazine has been investigated in a variety of psychiatric disorders,...
Approved
Investigational
Matched Synonyms: … trans-N-{4-[2-[4-(2,3-dichlorophenyl)piperazine-1-yl]ethyl]cyclohexyl}-N’,N’-dimethylurea hydrochloride …
Matched Iupac: … 3,3-dimethyl-1-[(1r,4r)-4-{2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl}cyclohexyl]urea …
Matched Description: … to treat schizophrenia, and manic or mixed episodes and depressive episodes associated with bipolar I ... receptors and as an antagonist at serotonin 5-HT2A receptors. ... [A247100] It works as a partial agonist at central dopamine D2, dopamine D3, and serotonin 5-HT1A …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Serotonin 5-HT1 Receptor Agonists ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Matched Products: … REAGİLA 1,5 MG SERT KAPSÜL, 28 ADET ... REAGİLA 1,5 MG SERT KAPSÜL, 30 ADET …
Levonorgestrel (LNG) is a synthetic progestogen similar to Progesterone used in contraception and hormone therapy.[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. Some of these devices...
Approved
Investigational
Matched Iupac: … (1R,3aS,3bR,9aR,9bS,11aS)-11a-ethyl-1-ethynyl-1-hydroxy-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H …
Matched Mixtures name: … PIL KB 1 KOMBINASI ... PIL KB 1 KOMBINASI ... PIL KB I KOMBINASI …
Matched Products: … POSTPİLL ONE 1,5 MG TABLET, 1 TABLET ... Navela 1,5 mg Tabletten ... NORLEVO 1,5 MG TABLET …
Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Approved
Vet approved
Matched Iupac: … (2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2- …
Matched Mixtures name: … Unasyn 1,5 g - Trockenstechampullen ... Ampicillin/Sulbactam Astro 1,5 g Pulver zur Herstellung einer Injektions- oder Infusionslösung ... Ampicillin Sodium and Sulbactam Sodium
Matched Salts name: … Ampicillin sodium
Matched Products: … Ampicillin Sodium ... AMPICILLIN SODIUM ... Ampicillin sodium
Aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in combination with other antineoplastic agents in chemotherapy protocols. It produces consistent but acceptable myelosuppression...
Approved
Investigational
Matched Salts cas: … 54301-16-5
Matched Products: … Amsidyl 75 mg/1,5 ml Konzentrat und Lösungsmittel für ein Konzentrat zur Herstellung einer Infusionslösung …
Poractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada. It is used to treat Respiratory Distress Syndrome (RDS) in premature infants with an endogenous pulmonary surfactant deficiency. Poractant alfa is an extract of natural porcine lung surfactant consisting of 99% polar lipids (mainly phospholipids)...
Approved
Matched Description: … Poractant alfa is a creamy white suspension of this extract in 0.9% sodium chloride solution. ... extract of natural porcine lung surfactant consisting of 99% polar lipids (mainly phospholipids) and 1% …
Matched Products: … CUROSURF 120 MG/1,5 ML INTRATRAKEAL SUSPANSIYON IÇEREN FLAKON, 1 ADET ... CUROSURF 240 MG/3 ML INTRATRAKEAL SUSPANSIYON IÇEREN FLAKON, 1 ADET …
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste. It is produced by fermentation of a sugar source, such as...
Approved
Vet approved
Matched Description: … (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste …
Matched Mixtures name: … BALANCE %1,5 GLIKOZ 1,25 MMOL / 1 KALSIYUM 2000 ML BIOFIN TORBA ... BALANCE %1,5 GLIKOZ 1,25 MMOL / 1 KALSIYUM 2500 ML BIOFIN TORBA ... BALANCE %1,5 GLIKOZ 1,75 MMOL / 1 KALSIYUM 2000 ML BIOFIN TORBA …
Matched Salts name: … Sodium lactate …
Matched Products: … Sodium Lactate ... Keri Original - Aha - Lotion 5% ... Keri Fast Absorbing - Aha - Lot 5% …
Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the kidneys than most other intravascular contrast agents.
Approved
Matched Iupac: … 5-{N-[3-(N-{3,5-bis[(2,3-dihydroxypropyl)carbamoyl]-2,4,6-triiodophenyl}acetamido)-2-hydroxypropyl]acetamido …
Matched Products: … VISIPAQUE INJ 320MG I/ML ... VISIPAQUE 270MG I /ML ... VISIPAQUE 320 MG I /ML …
Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Developed in 1957, it is structurally similar to other corticosteroids like hydrocortisone and prednisolone. Dexamethasone was granted FDA approval on 30 October 1958....
Approved
Investigational
Vet approved
Matched Synonyms: … 16α-Methyl-9α-fluoro-1-dehydrocortisol ... 1-Dehydro-16α-methyl-9α-fluorohydrocortisone ... 16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol …
Matched Iupac: … (1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H …
Matched Mixtures name: … Dexamethasone Sodium Phosphate 0.1% / Finasteride 0.1% / Minoxidil 5% ... NETİZON 5 MG+15 MG/5 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET ... Dexamethasone Sodium Phosphate 0.1% / Finasteride 0.1% / Minoxidil 5% / Tretinoin 0.025% …
Matched Salts name: … Dexamethasone sodium phosphate …
Matched Products: … Etacortilen 1,5 mg/ml Augentropfen, Lösung ... DEKSOFTAN 1 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET ... DEKORT 5 MG/5 ML GÖZ VE KULAK DAMLASI, ÇÖZELTİ, 5 ML …
Iopodic acid, also known by the name of ipodate, is classified as a cholecystographic agent formed by a weak organic acid that contains a tri-iodinated benzene ring with iodine at positions 2, 4 and 6. Due to its particular structure, it presents a high degree of lipid solubility and a...
Approved
Investigational
Withdrawn
Matched Salts name: … Ipodate sodium
Matched Categories: … sodium iopodate …
Matched Products: … Oragrafin Sodium 0.5gm …
A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
Approved
Illicit
Matched Synonyms: … 5-ethyl-5-isoamylbarbituric acid ... 5-ethyl-5-isopentylbarbituric acid ... 5-ethyl-5-(3-methylbutyl)barbituric acid …
Matched Iupac: … 5-ethyl-5-(3-methylbutyl)-1,3-diazinane-2,4,6-trione …
Matched Salts name: … Amobarbital sodium
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Amytal Sodium ... Amytal Sodium 500mg ... Amytal Sodium Cap 60mg …
Hypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. Being unstable in the pure form, hypochlorite is most commonly used for bleaching, disinfectation, and water treatment purposes in its salt form, sodium hypochlorite. Hypochlorite is often used as a chemical reagent for chlorination and oxidation...
Approved
Matched Description: … is most commonly used for bleaching, disinfectation, and water treatment purposes in its salt form, sodium
Matched Salts name: … Sodium hypochlorite …
Matched Categories: … Sodium Compounds ... sodium hypochlorite …
Matched Products: … Sodium hypochlorite disinfectant ... (Qiqing) Sodium Hypochlorite Disinfectant …
Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates.[A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative anxiety.[A201977,L13613] Butabarbital is less commonly used in recent years, as more patients are typically prescribed benzodiazepines. Its short duration of action...
Approved
Illicit
Matched Synonyms: … 5-ethyl-5-(1-methylpropyl)barbituric acid ... 5-ethyl-5-(1-methylpropyl)-2,4,6(1H,3H,5H)-pyrimidinetrione ... 5-sec-butyl-5-ethylbarbituric acid …
Matched Iupac: … 5-(butan-2-yl)-5-ethyl-1,3-diazinane-2,4,6-trione …
Matched Description: … [A201977,A201980] Butabarbital was granted FDA approval on 5 June 1939.[L13613] …
Matched Salts name: … Butabarbital sodium
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Butisol Sodium ... Butisol Sodium Tab 30mg ... Butisol Sodium Tab 15mg …
Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant,...
Approved
Investigational
Nutraceutical
Matched Synonyms: … (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid ... 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid (ECL) …
Matched Iupac: … (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid …
Matched Mixtures name: … Clindamycin 1% / Sodium Sulfacetamide Monohydrate 5% / Tretinoin 0.025% ... OLIVIA QUIDO FIRM and FADE I ... Dexamethasone Sodium Phosphate 0.1% / Finasteride 0.1% / Minoxidil 5% / Tretinoin 0.025% …
Matched Products: … ESTERA 1 MG/G ... S T I E V A-A …
Approved
Matched Iupac: … 9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1- …
Matched Salts name: … Hydrocortisone sodium succinate …
Matched Products: … HYDROCORT-LİYO 100 MG IM/IV ENJEKSİYON/ IV İNFÜZYON İÇİN LİYOFİLİZE TOZ İÇEREN AMPUL, 1 AMPUL VE 1 ÇÖZÜCÜ ... HYDROCORTISONE SODIUM SUCCINATE ... HIDROZON 100 MG IM/IV ENJEKSİYON/IV İNFÜZYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON+ÇÖZÜCÜ AMPÜL ,1 ADET …
Dextran is a polysaccharide that differs from others in that its glucose units are joined together 1:6 glucoside links. The main chain of glucose has short branches at frequent intervals which are probably joined by 1:3 and 1:4 glucoside links. The chains can be composed of about 200,000 glucose units....
Approved
Investigational
Vet approved
Matched Description: … Dextrose Injection or 0.9% Sodium Chloride Injection. ... 1:4 glucoside links. ... is a sterile, nonpyrogenic preparation of low molecular weight dextran (average mol. wt. 40,000) in 5% …
Matched Salts cas: … 9011-18-1
Matched Mixtures name: … TEARS NATURALE II 1 MG/ML + 3 MG/ML GÖZ DAMLASI ... Lmd 10% In Dextrose 5% ... Gentran 40 10% Dextrose 5% Inj …
Matched Salts name: … Dextran sulfate sodium ... Dextran sulfate sodium (MW 5000) ... Dextran sulfate sodium (MW 9500) ... Dextran sulfate sodium (MW 54000) ... Dextran sulfate sodium (MW 520000) …
Matched Products: … LMD in Sodium Chloride …
Chemically, dantrolene is a hydantoin derivative, but does not exhibit antiepileptic activity like other hydantoin derivates such as phenytoin.
Approved
Investigational
Matched Synonyms: … 1-((5-(p-nitrophenyl)furfurylidene)amino)hydantoin …
Matched Iupac: … 1-[(E)-{[5-(4-nitrophenyl)furan-2-yl]methylidene}amino]imidazolidine-2,4-dione …
Matched Salts name: … Dantrolene sodium
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Dantrolene Sodium ... RYANODEX dantrolene sodium ... Dantrolene Sodium for Injection, USP …
Displaying drugs 26 - 50 of 8504 in total