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Displaying drugs 476 - 500 of 12452 in total

Human botulinum neurotoxin A/B immune globulin

Infant botulism is a rare infectious disease occurring in infants in which Clostridium botulinum colonize the large intestine and being to produce botulinum neurotoxin directly in the gut. As these neurotoxins interfere with cholinergic nervous transmission, patients initially present with evident of loss of muscle tone (e.g. constipation, ptosis, feeding...
Approved

Cabotegravir

Cabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside reverse transcriptase inhibitor, rilpivirine.[A227668,L31188,L31193] Early research into cabotegravir showed it had lower oral bioavailability than dolutegravir, which resulted in the development of long acting monthly intramuscular injection formulation for cabotegravir.[A227668,L31193] Cabotegravir was granted FDA approval on...
Approved
Investigational
Matched Description: … Cabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside ... Cabotegravir was granted FDA approval on 21 January 2021 in combination with rilpivirine to treat HIV-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Organic Anion Transporter 1 Inhibitors …

Lumiracoxib

Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID). On August 11, 2007, Australia's Therapeutic Goods Administration (TGA, the Australian equivalent of the FDA) cancelled the registration of lumiracoxib in Australia due to concerns that it may cause liver failure. New Zealand and Canada have also followed suit in recalling...
Approved
Investigational
Matched Synonyms: … 2-((2-chloro-6-fluorophenyl)amino)-5-methylbenzeneacetic acid …
Matched Iupac: … 2-{2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid …
Matched Description: … Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID). …
Matched Categories: … COX-2 Inhibitors ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …

Influenza B virus B/Massachusetts/2/2012 BX-51B antigen (formaldehyde inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Synonyms: … Influenza B Virus B/massachusetts/2/2012 Nymc Bx-51b Antigen (Formaldehyde Inactivated) …
Matched Name: … Influenza B virus B/Massachusetts/2/2012 BX-51B antigen (formaldehyde inactivated) …

Thrombin

Also known as coagulation factor II, thrombin is a serine protease that plays a physiological role in regulating hemostasis and maintaining blood coagulation. Once converted from prothrombin, thrombin converts fibrinogen to fibrin, which, in combination with platelets from the blood, forms a clot. Medical thrombin is a protein substance produced...
Approved
Investigational
Matched Mixtures name: … , SET 1 (2 İĞNE+2 ENJEKTÖR) VE SET 2 (2 İĞNE +2 ENJEKTÖR+1 ENJEKTÖR KLİPSİ+2 BİRLEŞTİRME PARÇASI+ 4 APLİKASYON ... TISSEEL 2 ML KULLANIMA HAZIR ENJEKTÖR 1 ADET ... ARTISS 2 ML ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTOR, 1 ADET …

Plecanatide

Plecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation (CIC). It should not be used in children less than six years of age, and should be avoided in patients six years to 18 years of age
Approved
Investigational
Matched Iupac: … (4S)-4-{[(2S)-2-{[(2S)-2-amino-1-hydroxy-3-(C-hydroxycarbonimidoyl)propylidene]amino}-3-carboxy-1-hydroxypropylidene ... -32-[(1R)-1-hydroxyethyl]-4-methyl-19-(2-methylpropyl)-7,13-bis(propan-2-yl)-27,28,40,41-tetrathia-2,5,8,11,14,17,20,23,31,34,37 ... ]amino}-4-{[(1R,4S,7S,10S,13S,16R,19S,22S,25R,32S,38R)-38-{[(1S)-1-carboxy-3-methylbutyl]-C-hydroxycarbonimidoyl ... }-22-(2-carboxyethyl)-3,6,9,12,15,18,21,24,30,33,36-undecahydroxy-10-[(C-hydroxycarbonimidoyl)methyl] …

Influenza A virus A/Victoria/4897/2022 IVR-238 (H1N1) Antigen (propiolactone inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved

Articaine

Articaine is a dental local anesthetic. Articaine is widely used around the world and is the most popular local anesthetic in many European countries.
Approved
Matched Iupac: … methyl 4-methyl-3-[2-(propylamino)propanamido]thiophene-2-carboxylate …
Matched Mixtures name: … Septanest mit Epinephrin 1:200.000 40 mg/ml + 5 Mikrogramm/ml Injektionslösung ... MAXİCAİNE 80 MG/2 ML+0,01 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL ... Orabloc 40 mg/ml + 5 Mikrogramm/ml Injektionslösung …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Mestranol

The 3-methyl ether of ethinyl estradiol. It must be demethylated to be biologically active. It is used as the estrogen component of many combination ORAL contraceptives.
Approved
Matched Iupac: … [a]phenanthren-1-ol ... (1R,3aS,3bR,9bS,11aS)-1-ethynyl-7-methoxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta …
Matched Mixtures name: … Norinyl 1/50 28 Tab ... Norinyl 1/50 21 Tab ... Norinyl 1/50 -(21-day Regimen) …

Cetalkonium

Cetalkonium is a C16 alkyl benzalkonium chloride derivative with an amphipathic property which allows it to be used in different types of formulations. It is a quaternary ammonium salt that acts as an antiseptic against a variety of bacteria and fungi. Cetalkonium is approved by the FDA for its use...
Approved
Matched Salts cas: … 3529-04-2 …

Polyethylene glycol 400

Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions. Because many PEG types are hydrophilic, they are favorably used as enhancers of penetration, and used heavily in topical dermatological preparations. PEGs, along with their many nonionic derivatives, are...
Approved

Curcumin

Curcumin, also known as diferuloylmethane, is an active component in the golden spice turmeric (Curcuma longa) and in Curcuma xanthorrhiza oil. It is a highly pleiotropic molecule that exhibits antibacterial, anti-inflammatory, hypoglycemic, antioxidant, wound-healing, and antimicrobial activities . Due to these properties, curcumin has been investigated for the treatment and...
Approved
Investigational

Masoprocol

A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils. [PubChem]
Approved
Investigational

Desipramine

Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, desipramine exerts a positive...
Approved
Investigational
Matched Synonyms: … 5-(γ-methylaminopropyl)iminodibenzyl ... 5-(gamma-methylaminopropyl)iminodibenzyl …
Matched Iupac: … (3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}propyl)(methyl)amine …
Matched Description: … TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists …

Perflutren

Perflutren, a diagnostic drug that is intended to be used for contrast enhancement during the indicated echocardiographic procedures, is comprised of lipid-coated microspheres filled with octafluoropropane(OFP) gas. When exposed to ultrasound waves, the microspheres resonate and "echo" strong signals back to the ultrasound machine. The difference in density between the...
Approved

Sodium phosphate, monobasic

Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.
Approved
Matched Salts cas: … 10049-21-5 …
Matched Mixtures name: … K-Phos No. 2 ... AMINOPLASMAL-5% E INFUSION ... Cpda-1 …

Zaleplon

Zaleplon is a sedative/hypnotic, mainly used for insomnia. It is known as a nonbenzodiazepine hypnotic. Zaleplon interacts with the GABA receptor complex and shares some of the pharmacological properties of the benzodiazepines. Zaleplon is a schedule IV drug in the United States.
Approved
Illicit
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … SONATA ® 5 MG. CAPSULAS …

Thalidomide

A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, thalidomide was withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of inflammatory disorders and cancers. Thalidomide displays immunosuppressive and anti-angiogenic activity through modulating the release of inflammatory mediators like tumor necrosis factor-alpha...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline …
Matched Iupac: … 2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

Penicillium chrysogenum var. chrysogenum

Penicillium chrysogenum var. chrysogenum is a fungus which can provoke allergic reactions. Penicillium chrysogenum var. chrysogenum extract is used in allergenic testing.
Approved
Matched Mixtures name: … Mold Mix 1 ... Mold Mix 1 ... Mold Mix 1 …

Soybean oil

Derived from soybeans, soybean oil is a common vegetable oil and a source of polyunsaturated and saturated fatty acids. It is a complex mixture of triglycerides where per 100 g, soybean oil has 16 g of saturated fat, 23 g of monounsaturated fat, and 58 g of polyunsaturated fat. The...
Approved
Matched Mixtures name: … OLEUNOR Peri 2,5% mit Elektrolyten Emulsion zur Infusion ... PeriOLIMEL 2,5 % mit Elektrolyten - Emulsion zur Infusion …

Influenza A virus A/Texas/50/2012 X-223A (H3N2) hemagglutinin antigen (MDCK cell derived, propiolactone inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved

Burosumab

Burosumab (KRN23) is an entirely human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic rickets . The U.S. Food and Drug Administration approved Crysvita (burosumab) in April 2018. This is the first drug approved...
Approved
Investigational
Matched Description: … This is the first drug approved to treat adults and children ages 1 year and older with X-linked hypophosphatemia …

Mebutamate

Mebutamate is a sedative and anxiolytic drug with anti-hypertensive (blood pressure lowering) effects comparable to those of other barbiturates but is only around 1/3rd the potency of secobarbital as a sedative. Side effects include dizziness and headaches.
Approved
Matched Synonyms: … 2-Methyl-2-sec-butyl-1,3-propanediol dicarbamate ... 2-sec-Butyl-2-methyl-1,3-propanediol dicarbamate ... 2-sec-Butyl-2-methyltrimethylene dicarbamate …
Matched Iupac: … 2-[(carbamoyloxy)methyl]-2,3-dimethylpentyl carbamate …
Matched Description: … anti-hypertensive (blood pressure lowering) effects comparable to those of other barbiturates but is only around 1/ …

Peginterferon beta-1a

Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of...
Approved
Matched Mixtures name: … ADET 63 MGC/0.5 ML+1 ADET 94 MCG/0.5 ML ... ADET 63 MGC/0.5 ML+1 ADET 94 MCG/0.5 ML ... 0.5 ML+94 MCG/0.5 ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM TEDAVİYE BAŞLAMA PAKETİ , 1 …
Matched Products: … PLEGRİDY 125 MCG/0.5 ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET …

Methocarbamol

Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated pain.[A178441,A178450] It is a guaiacol glyceryl ether. Methocarbamol tablets and intramuscular injections are prescription medicines indicated in the United States as an adjunct to rest, physical therapy, and other measures for the relief of...
Approved
Vet approved
Matched Synonyms: … (RS)-2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate …
Matched Iupac: … 2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate …
Matched Mixtures name: … Robaxisal C 1/2 ... Methoxisal-C 1/2 ... Robaxisal C 1/4 …
Displaying drugs 476 - 500 of 12452 in total