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Displaying drugs 476 - 500 of 955 in total
Experimental
Matched Name: … ISOPENTENYL PYROPHOSPHATE
Tirapazamine, also known as SR-4233, is an experimental anticancer drug that is activated in hypoxic conditions. This activation is very useful as this hypoxic state is found in human solid tumors in a common phenomenon known as tumor hypoxia. Hence, tirapazamine is solely activated in those hypoxic areas of solid...
Investigational
Matched Synonyms: … 1,2,4-benzotriazin-3-amine, 1,4-dioxide ... 3-Amino-1,2,4-benzotriazine 1,4-dioxide
Matched Description: … Tirapazamine entered phase III testing in 2006 for patients with head and neck cancer and gynecological ... into consideration that normally, the cells in these hypoxic regions are resistant to radiotherapy and
Vasopressin (arginine-vasopressin or antidiuretic hormone) is a nonapeptide primarily produced in the hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and behaviour.[A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and eighth amino acids. Despite a wide variety of functions, exogenous...
Approved
Matched Description: … renal fluid reuptake by acting through V1 and V2 cellular receptors. ... [A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and ... hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Vasopressin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Vasopressin in 0.9% Sodium Chloride …
Approved
Experimental
Investigational
Matched Synonyms: … Sodium choleate …
Matched Mixtures name: … Pancreatin and Enzyme Formula - Tablet …
Matched Categories: … Bile Acids and Salts …
Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the the treatment of...
Approved
Matched Description: … kidneys and the inner ear. ... It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to ... liquid treatment option available for the the treatment of _Clostridium difficile_ associated diarrhea and
Matched Mixtures name: … Vancomycin Hydrochloride ... Vancomycin Hydrochloride ... Vancomycin Hydrochloride
Matched Salts name: … Vancomycin hydrochloride
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Products: … Vancomycin Injection USP In 0.9% Sodium Chloride ... Vancomycin Hydrochloride ... Vancomycin Hydrocloride
Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric...
Approved
Investigational
Matched Description: … Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. …
Matched Salts name: … Trimethobenzamide hydrochloride
Matched Products: … Trimethobenzamide Hydrochloride ... Trimethobenzamide hydrochloride ... Trimethobenzamide Hydorchloride
Cefoperazone is a semisynthetic broad-spectrum cephalosporin proposed to be effective against Pseudomonas infections. It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections caused by susceptible organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and bacterial septicemia. While its...
Approved
Investigational
Matched Description: … It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections ... organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and
Matched Mixtures name: … CEFOPERAZONE SODIUM - SULBACTAM SODIUM ... CEFOPERAZONE SODIUM - SULBACTAM SODIUM ... CEFOPERAZONE SODIUM - SULBACTAM SODIUM
Matched Salts name: … Cefoperazone sodium
Matched Products: … CEFOPERAZONE SODIUM
A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe...
Approved
Withdrawn
Matched Description: … It has few side effects and is reported to be safe and effective in aged patients and in patients with ... of both aerobic and anaerobic gram-positive and gram-negative organisms. ... The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range …
Matched Salts name: … Ceftizoxime sodium
Matched Products: … CEFTIZOXIME SODIUM
Experimental
Matched Name: … Magnesium aspartate hydrochloride
Matched Iupac: … magnesium(2+) (2S)-2-aminobutanedioate hydrochloride
Matched Salts name: … Magnesium aspartate hydrochloride trihydrate …
Mucor circinelloides f. lusitanicus allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, mucor circinelloides f. lusitanicus …
Investigational
Matched Synonyms: … antibody-drug conjugate comprised of a human aglycosylated anti-CD74 IgG1 antibody (SP7219) and two non-cleavable …
PRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface.
Investigational
Matched Synonyms: … genetically modified using a non-viral system to express a CD33 CAR, membrane bound Interleukin-15, and
Matched Description: … genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and
Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously. Because it can cause blood stagnation, it is important to monitor changes in...
Approved
Investigational
Matched Description: … monitor changes in hematocrit, activated partial thromboplastin time, international normalized ratio and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … Bivalirudin in 0.9% Sodium Chloride …
Demplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer).
Investigational
Matched Synonyms: … A micelle drug formulation composed of cisplatin and mPEG-poly(l-Glu) diblock copolymer with 1,3-propanediyl …
Matched Description: … pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Meclizine is a histamine H1 antagonist with antiemetic and antivertigo properties. It is used in the symptomatic treatment of motion sickness and control of vertigo associated with vestibular system diseases. It also exhibits anticholinergic, central nervous system depressant, and local anesthetic effects. Commonly marketed under the brand name Antivert in...
Approved
Matched Description: … Meclizine is a histamine H1 antagonist with antiemetic and antivertigo properties. ... It also exhibits anticholinergic, central nervous system depressant, and local anesthetic effects. ... It is used in the symptomatic treatment of motion sickness and control of vertigo associated with vestibular …
Matched Salts name: … Meclizine hydrochloride
Matched Products: … Meclizine Hydrochloride ... Meclizine Hydrocloride ... Meclizine hydrochloride
Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration. Menthol mediates anesthetic properties and...
Approved
Matched Description: … . (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration ... Menthol mediates anesthetic properties and anti-irritating properties locally, thus it is widely used …
Matched Mixtures name: … Jack and Jill Rub ... Half and Half Balm ... Satohap Cool and Hot Pads …
Matched Categories: … Basic Lotions and Liniments ... Antipruritics and Local Anesthetics ... Herbs and Natural Products ... Other Cold and Cough Preparations …
Matched Products: … Musle and Joint ... Performance and Recovery …
Experimental
Matched Synonyms: … 2-Amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphate
A pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with...
Approved
Matched Description: … A pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. ... Negative potential reduces secretion of potassium and hydrogen ions. ... (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705) …
Matched Mixtures name: … Amiloride Hydrochloride and Hydrochlorothiazide ... Amiloride Hydrochloride and Hydrochlorothiazide ... Amiloride Hydrochloride and Hydrochlorothiazide …
Matched Salts name: … Amiloride hydrochloride ... Amiloride hydrochloride dihydrate …
Matched Categories: … Sodium Channel Blockers ... Epithelial Sodium Channel Blockers …
Matched Products: … Amiloride Hydrochloride ... Amiloride Hydrocloride ... Amiloride Hydrochloride Tablets, USP …
Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid. It is a topical analgesic used for temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and bruises. Unlike other topical analgesics, trolamine...
Approved
Matched Description: … Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid ... temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and ... It also displays low systemic absorption upon dermal or topical administration [A32190] and has low skin …
Matched Products: … Up and Up Pain Relief Odorless ... Up and Up Odor-free Pain Relieving Cream …
Experimental
Matched Name: … Zirconium dioxide
Experimental
Matched Name: … Calcium fluoride
Matched Categories: … Fluorides ... Fluorine Compounds …
Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the levorotatory form (levopanthenol). While pantothenic acid is optically active, only the dextrorotatory...
Approved
Matched Description: … Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an ... Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the ... Due to its good penetration and high local concentrations, dexpanthanol is used in many topical products …
Matched Mixtures name: … Therapytion Nokmosu Sensitive and Dry Hair ... Therapytion Nokmosu Neutral and oily Hair …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … BABOR Baborganic Calm and Relax …
Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.[L7550,L7553,L7556,L7559,L7562,L7565]
Approved
Investigational
Nutraceutical
Matched Synonyms: … pyridine-β-carboxylic acid …
Matched Iupac: … pyridine-3-carboxylic acid …
Matched Description: … vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and
Matched Mixtures name: … Multi-Vitamin Fluoride and Iron Drops ... Niacin 500 Mg and Inositol ... Myhephron Dialysis and Stress Supplement …
Matched Categories: … Diet, Food, and Nutrition ... Nicotinic Acid and Derivatives ... lovastatin and nicotinic acid …
Matched Products: … JEUNCELL Hair restorer and Hair Growth Solution …
Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Description: … Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and ... inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and
Matched Salts name: … Methotrexate sodium
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Methotrexate Sodium ... Ratio-methotrexate Sodium ... Methotrexate Sodium Inj 20mg …
Experimental
Matched Synonyms: … Hydrochloric acid …
Matched Name: … Hydrochloric acid …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... hydrochloric acid ... hydrochloric acid ... Blood Substitutes and Perfusion Solutions …
Displaying drugs 476 - 500 of 955 in total