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Displaying drugs 501 - 525 of 606 in total

Mozafancogene autotemcel

RP-L102 is a lentiviral vector carrying the Fanconi Anemia-A (FANCA) gene currently being developed by Rocket Pharmaceuticals for the treatment of Fanconi anemia type A
Investigational
Matched Synonyms: … Autologous CD34+-enriched Hematopoietic Stem and Progenitor Cells Transduced with Lentiviral Vector Carrying …

CP-12

Investigational
Matched Synonyms: … CYCLIZED P12 (PEPTIDE BOND BETWEEN THE CARBOXY AND AMINO-TERMINAL ENDS OF THE LINEAR PEPTIDE PSHISKYILRWRPK …

Factor IX Complex (Human)

Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels of...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX, II, VII and X in combination …
Matched Description: … Coagulation factors are purified from pooled human plasma and subsequently sterilized and treated. ... For example, Kcentra (FDA) also contains the antithrombotic proteins C and S, while Bebulin VH (FDA) ... include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …

Atidarsagene autotemcel

Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC …
Matched Description: … Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

4-O-Demethylpenclomedine

Investigational
Matched International brands: … Clomet …

Nogapendekin alfa

Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Fusion protein consisting of il-15n72d and il-15rasu/fc …
Matched Description: … 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG ... Nogapendekin alfa, in combination with inbakicept, mimics the actions of IL-15, , stimulating the activation and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Zamerovimab

Investigational
Matched Synonyms: … .1-chain), disulfide with human-mus musculus clone 1a9 .kappa. ... Immunoglobulin g1, anti-(rabies lyssavirus spike glycoprotein g) (human-mus musculus clone 1a9 .gamma …

Tilmicosin

Tilmicosin is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia haemolytica.
Investigational
Vet approved
Matched Description: … It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory …
Matched Products: … Tilmovet® 200 g/kg Premix for Medicated Feeding Stuff for Pigs and Rabbits …

Mazorelvimab

Investigational
Matched Synonyms: … .1-chain), disulfide with human-mus musculus clone 2g11 .kappa. ... Immunoglobulin g1, anti-(rabies lyssavirus spike glycoprotein g) (human-mus musculus clone 2g11 .gamma …

Elapegademase

Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED ON N.ALPHA..1ALANINE AND ... 356)-PEPTIDE, PRODUCED IN ESCHERICHIA COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND …
Matched Description: … as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on ... with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …

Clodronic acid

Clodronic acid is a first generation bisphosphonate similar to etidronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. clodronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Investigational
Vet approved
Matched Description: … Clodronic acid is a first generation bisphosphonate similar to [etidronic acid] and [tiludronic acid] ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and ... generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization …
Matched Products: … CLODY …

Oleic Acid

An unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. (Stedman, 26th ed)
Approved
Investigational
Vet approved
Matched Name: … Oleic Acid …
Matched Description: … It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. ... An unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. …
Matched Mixtures name: … Borage Oil Capsules ... Gla 130 Primrose Oil ... Flaxseed Oil Capsules …
Matched Salts name: … Oleate sodium ... Calcium oleate …
Matched Categories: … Oleic Acids …

Clobetasone

Clobetasone is a corticosteroid that is often employed topically as a treatment for a variety of conditions such as eczema, psoriasis, various forms of dermatitis, and also for certain ophthalmologic conditions. Topical clobetasone butyrate has shown minimal suppression of the Hypothalamic-pituitary-adrenal axis.
Approved
Matched Description: … as a treatment for a variety of conditions such as eczema, psoriasis, various forms of dermatitis, and …
Matched Categories: … clobetasone and antiinfectives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … CLOBET …

Fluorescein

A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma. It has been approved by FDA for use in externally applied drugs...
Approved
Matched Synonyms: … D and C Yellow No. 7 …
Matched Description: … and corneal trauma. ... It has been approved by FDA for use in externally applied drugs and cosmetics. ... A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline …
Matched Mixtures name: … Minims Lidocaine and Fluorescein ... Fluorescein Sodium and Proparacaine Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride …
Matched Categories: … Indicators and Reagents …

Ivermectin

Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro­-25-(1-methylethyl)avermectin A1a (22,23-dihydroavermectin B1b). Ivermectin is mainly used in...
Approved
Investigational
Vet approved
Matched Description: … use for the prophylaxis and treatment of COVID-19. ... roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and ... also be effective against other worm infestations (such as strongyloidiasis, ascariasis, trichuriasis and …
Matched Categories: … Scabicides and Pediculicides ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … IVOMEC Injection 1% w/v for Cattle and Sheep …

Chlorhexidine

Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of...
Approved
Vet approved
Withdrawn
Matched Description: … Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental ... [L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today. ... [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two …
Matched Mixtures name: … (Fruli) Quick-Dry Disposable Hand Sanitizer ... CLODER PLUS GARGARA, 200 ML ... CLODER PLUS 30 ML ORAL SPREY …
Matched Categories: … Alimentary Tract and Metabolism ... Biguanides and Amidines ... Antiseptics and Disinfectants ... Mouthwashes and Gargles ... chlorhexidine and cetylpyridinium …
Matched Products: … Zedoary Oils Feminine Antibacterial Gels ... Foster and Thrive ... META CLOR ANTISÉPTICO …

Dextromethorphan

Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997]
Approved
Matched Description: … and also a drug of abuse. ... Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant …
Matched Mixtures name: … Topco tussin cf max ... Top Care Day Time Multi Symptom Relief ... Up and Up Flu and Severe Cold and Cough Relief …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives ... bupropion and dextromethorphan …
Matched Products: … Up and Up Cough Suppressant DM ... Up and Up 12 Hour Cough Relief ... Foster and Thrive 12 Hour Cough Relief …

Mucor circinelloides f. circinelloides

Mucor circinelloides f. circinelloides allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, mucor circinelloides f. circinelloides …

Cholecalciferol

Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Matched Description: … C23 and has an additional methyl group at C24 [L5689]. ... of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and ... the plant-derived form, vitamin D2 (ergocalciferol), are considered the main forms of vitamin d and …
Matched Mixtures name: … Cod Liver Oil USP ... Cod Liver Oil Cap ... Cod Liver Oil Oleovitamin A & D Caps 20min …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... Vitamin D and Analogues ... Calcium-Regulating Hormones and Agents ... ibandronic acid and colecalciferol …
Matched Products: … OLEO-D3 800 I.E. Filmtabletten ... OLEO-D3 1.000 I.E. Filmtabletten ... OLEO-D3 7.000 I.E. Filmtabletten …

Dermatophagoides pteronyssinus

Dermatophagoides pteronyssinus extracts are sterile solutions used for intradermal testing or subcutaneous immunotherapy. This combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies.
Approved
Matched Synonyms: … European house dust mite ... European house dust mite extract …
Matched Mixtures name: … Standardized Mite Mix Dermatophagoides farinae and Dermatophagoides pteronyssinus ... Standardized Mite Mix Dermatophagoides farinae and Dermatophagoides pteronyssinus ... Standardized Mite Mix, Dermatophagoides pteronyssinus and Dermatophagoides farinae, 10000 AU per mL …

Tranexamic acid

Tranexamic acid is a synthetic derivative of lysine used as an antifibrinolytic in the treatment and prevention of major bleeding. It possesses a similar mechanism of action to aminocaproic acid but is approximately 10-fold more potent. It was first patented in 1957 and received its initial US approval in 1986.
Approved
Matched Description: … Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and ... [L31883] It was first patented in 1957[A230108] and received its initial US approval in 1986. …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … CLONEX ... CLONEX 250 ... CLONEX 500 …

Acetylsalicylic acid

Also known as Aspirin, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction...
Approved
Vet approved
Matched Description: … This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and ... in many doses and forms, including chewable tablets, suppositories, extended release formulations, and ... Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. …
Matched Mixtures name: … GOODYS Extra Strength Headache Mixed Fruit Blast ... Top Value Effervescent Cold Relief ... Top Value Effervescent Pain Relief …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Salicylic Acid and Derivatives ... codeine and acetylsalicylic acid ... sotalol and acetylsalicylic acid …
Matched Products: … Up and Up Aspirin ... Up and Up aspirin ... Berkley and Jensen Aspirin …

Omega-3-acid ethyl esters

Omega-3-acid ethyl esters are prescription drugs that contain eicosapentaenoic acid-ethyl ester (EPA) and docosahexaenoic acid-ethyl ester (DHA) that are used in combination with changes in diet to lower triglyceride levels in adults with severe (≥ 500 mg/dL) hypertriglyceridemia[FDA Label] . Omega-3-acid ethyl esters are currently marketed in the US, EU,...
Approved
Investigational
Matched Description: … Omega-3-acid ethyl esters are prescription drugs that contain eicosapentaenoic acid-ethyl ester (EPA) and ... Omega-3-acid ethyl esters are currently marketed in the US, EU, and many other regions under the brand …
Matched Categories: … Diet, Food, and Nutrition ... Oils ... Fish Oils …
Matched Products: … OLEVIA …

Coagulation Factor IX Human

Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B.
Approved
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... coagulation factor IX, II, VII and X in combination …
Matched Products: … IMMUNINE 120IU/ML Powder and solvent for solution for injection or infusion …

Insulin lispro

Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the pancreas...
Approved
Matched Description: … and proteolysis among many other functions. ... tissues such as the liver, fat cells, and skeletal muscle. ... Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Insulins and Analogues for Injection, Fast-Acting ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 KwikPen …
Displaying drugs 501 - 525 of 606 in total