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Displaying drugs 501 - 525 of 732 in total

Promethazine

Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of phenothiazine that was developed in France in 1946. Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.[A189907,A190153,A190159,A190150,A190171] Promethazine was granted FDA approval before 29...
Approved
Investigational
Matched Description: … allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and …
Matched Mixtures name: … Promethazine Hydrochloride and Phenylephrine Hydrochloride ... Promethazine Hydrochloride and Phenylephrine Hydrochloride ... Meperidine Hydrochloride and Promethazine Hydrochloride …
Matched Salts name: … Promethazine hydrochloride …
Matched Categories: … prednisolone and promethazine ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Promethazine Hydrochloride ... Promethazine hydrochloride ... Promethazine Hydrochloride Injection USP …

Yohimbine

A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
Approved
Investigational
Vet approved
Matched Description: … Yohimbine has been used as a mydriatic and in the treatment of impotence. …
Matched Salts name: … Yohimbine hydrochloride …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … Yohimbine Hydrochloride Tab 2mg ... Yohimbine Hydrochloride Tablets 5.4mg …

Betahistine

Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Synonyms: … 2-(β-methylaminoethyl)pyridine ... 2-[2-(methylamino)ethyl]pyridine …
Matched Description: … Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing ... It has a significant impact on both the physical and social functioning of affected individuals. …
Matched Salts name: … Betahistine hydrochloride …
Matched Products: … BETAHISTINE HYDROCHLORIDE …

Mefloquine

Malaria is a protozoan disease that places an enormous burden on human health in endemic areas around the world. The 2020 World Health Organization malaria report indicates a 60% decrease in the global malaria fatality rate between 2000 to 2019. Despite this, malaria remains a significant cause of morbidity and...
Approved
Investigational
Matched Description: … Eastern Africa, nonimmune civilian and military travelers, pregnant women, and immigrants traveling ... It was approved by the FDA in 1989, and was first marketed by Hoffman Laroche. ... treatment of malaria caused by infection with Plasmodium vivax and Plasmodium falciparum. …
Matched Salts name: … Mefloquine hydrochloride …
Matched Categories: … artesunate and mefloquine ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … Mefloquine Hydrochloride …

Dipivefrin

Dipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution (eye drops).
Approved
Matched Salts name: … Dipivefrin hydrochloride …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Dipivefrin Hydrochloride …

Ropivacaine

Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.
Approved
Matched Description: … It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the …
Matched Salts name: … Ropivacaine hydrochloride ... Ropivacaine hydrochloride anhydrous …
Matched Products: … Ropivacaine Hydrochloride ... Ropivacaine hydrochloride ... Ropivacaine Hydrochloride Injection …

Eperisone

Eperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression of the pain reflex. It is not approved for use in the United States, but is available in other countries...
Investigational
Matched Description: … Eperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and ... demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression ... approved for use in the United States, but is available in other countries like India, South Korea, and …
Matched Salts name: … Eperisone hydrochloride …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers …
Matched Products: … EPERISONE HYDROCHLORIDE ... EPERISON HYDROCHLORIDE …

Tirofiban

Tirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery. It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits platelet aggregation.
Approved
Matched Description: … It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits …
Matched Salts name: … Tirofiban hydrochloride …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … Tirofiban Hydrochloride ... Tirofiban hydrochloride …

Buspirone

Buspirone is a novel anxiolytic agent with a unique structure and a pharmacological profile. Belonging to the azaspirodecanedione drug class, buspirone is a serotonin 5-HT1A receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates, and other sedative/anxiolytic drugs. Unlike many drugs used to treat anxiety, buspirone does...
Approved
Investigational
Matched Description: … Buspirone is a novel anxiolytic agent with a unique structure and a pharmacological profile. ... , such as generalized anxiety disorder (GAD), and relieve symptoms of anxiety. ... receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates, and …
Matched Salts name: … Buspirone hydrochloride …
Matched Categories: … Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Buspirone Hydrochloride ... BusPIRone Hydrochloride ... Buspirone hydrochloride …

Terazosin

Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label] . Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate .
Approved
Matched Description: … quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and ... adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and …
Matched Salts name: … Terazosin hydrochloride ... Terazosin hydrochloride hydrate …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … Terazosin Hydrochloride ... Terazosin hydrochloride ... Terazosin Hydrochloride Anhydrous …

Mexiletine

Antiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.
Approved
Investigational
Matched Salts name: … Mexiletine hydrochloride …
Matched Products: … Mexiletine Hydrochloride ... Mexiletine hydrochloride …

Hydromorphone

Hydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and...
Approved
Illicit
Matched Description: … the absence of a double bond between the carbon 7 and 8. ... A176495] The first reported approved product containing hydromorphone in the form of hydromorphone hydrochloride ... was developed by Fresenius Kabi USA and FDA approved in 1984. …
Matched Salts name: … Hydromorphone hydrochloride …
Matched Categories: … hydromorphone and naloxone ... hydromorphone and antispasmodics …
Matched Products: … Hydromorphone Hydrochloride ... Hydromorphone hydrochloride ... HYDROmorphone Hydrochloride …

Metoclopramide

Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to...
Approved
Investigational
Matched Description: … impact on quality of life and poses a significant burden on the healthcare system. ... Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative ... [A184934] Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated …
Matched Salts name: … Metoclopramide hydrochloride ... Metoclopramide hydrochloride anhydrous …
Matched Categories: … Alimentary Tract and Metabolism ... Benzamides and benzamide derivatives …
Matched Products: … Metoclopramide Hydrochloride ... METOCLOPRAMIDE hydrochloride ... Metoclopramide hydrochloride …

Levobunolol

A nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma.
Approved
Matched Salts name: … Levobunolol hydrochloride …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Levobunolol Hydrochloride ... Levobunolol Hydrochloride Ophthalmic Solution …

Procaterol

A long-acting beta-2-adrenergic receptor agonist. It is a potent bronchodilator that may be administered orally or by aerosol inhalation.
Approved
Investigational
Matched Salts name: … Procaterol hydrochloride ... Procaterol hydrochloride hemihydrate …
Matched Products: … PROCATEROL HYDROCHLORIDE HEMIHYDRATE …

Darigabat

Darigabat is under investigation in clinical trial NCT05941442 (A Study to Evaluate Efficacy, Safety, and Tolerability of Darigabat in Participants With Panic Disorder).
Investigational
Matched Synonyms: … 7-ethyl-4-(4'-(ethylsulfonyl)-6-fluoro-2'-methoxybiphenyl-3-yl)-7h-imidazo(4,5-c)-pyridazine ... 7h-imidazo(4,5-c)pyridazine, 7-ethyl-4-(4'-(ethylsulfonyl)-6-fluoro-2'-methoxy(1,1'-biphenyl)-3-yl)- …
Matched Description: … Darigabat is under investigation in clinical trial NCT05941442 (A Study to Evaluate Efficacy, Safety, and …

Docetaxel

Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Description: … Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of [paclitaxel]. ... chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and ... microtubulin with high affinity in a 1:1 stoichiometric ratio, allowing it to prevent cell division and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Oncotaxel Concentrate and solvent for solution for infusion 40 mg/ ml …

Vilazodone

Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. Vilazodone may also be associated with less sexual dysfunction and weight gain . Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].
Approved
Matched Description: … (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. ... Vilazodone may also be associated with less sexual dysfunction and weight gain[A6947]. ... Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine …
Matched Salts name: … Vilazodone hydrochloride …
Matched Categories: … Serotonin antagonist and reuptake inhibitors (SARIs) …
Matched Products: … Vilazodone Hydrochloride ... Vilazodone hydrochloride …

Trimethoprim

Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival. Trimethoprim is often used in combination with sulfamethoxazole due to their...
Approved
Vet approved
Matched Description: … the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ... L11893] Trimethoprim is often used in combination with [sulfamethoxazole] due to their complementary and ... synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of urinary …
Matched Mixtures name: … Sulfamethoxazole and Trimethoprim ... Sulfamethoxazole and Trimethoprim ... Sulfamethoxazole and Trimethoprim …
Matched Salts name: … Trimethoprim hydrochloride …
Matched Categories: … isoniazid, sulfamethoxazole, trimethoprim and pyridoxine ... Trimethoprim and Derivatives ... sulfamoxole and trimethoprim ... Sulfonamides and trimethoprim ... sulfametrole and trimethoprim …
Matched Products: … TRIMPEX trimethoprim hydrochloride …

Topotecan

An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Approved
Investigational
Matched Salts name: … Topotecan hydrochloride …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Topotecan hydrochloride ... Topotecan Hydrochloride ... Topotecan Hydrochloride for Injection …

Quinoline

Investigational
Matched Synonyms: … Benzo(b)pyridine …

Nalmefene

Nalmefene, a 6-methylene analogue of naltrexone, is an opioid receptor antagonist. It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist at the kappa (κ)-opioid receptor. In Europe, nalmefene oral tablets are used to reduce alcohol consumption in adults with alcohol dependence. Nalmefene...
Approved
Investigational
Withdrawn
Matched Description: … [L40684] It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist …
Matched Salts name: … Nalmefene hydrochloride ... Nalmefene hydrochloride dihydrate …
Matched Products: … Nalmefene Hydrochloride …

Imipramine

Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts...
Approved
Matched Description: … and clomipramine. ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... than secondary amine TCAs, such as nortriptyline and desipramine. …
Matched Salts name: … Imipramine hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Imipramine Hydrochloride ... Imipramine hydrochloride ... Imipramine Hydrochloride Tablets 25mg …

Isoprenaline

Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and cardiogenic shock.[A15638,L33160] Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising...
Approved
Investigational
Matched Description: … anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and ... [A233724,A233729] The US patent from 1943 states that this compound had a wider therapeutic index and ... found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising the heart rate and …
Matched Salts name: … Isoprenaline hydrochloride …
Matched Categories: … Adrenergic and Dopaminergic Agents ... isoprenaline and other drugs for obstructive airway diseases …
Matched Products: … Isoproterenol Hydrochloride ... Isoproterenol hydrochloride ... Isoproterenol Hydrochloride Injection USP …

Meperidine

A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Approved
Matched Description: … that can be used for the relief of most types of moderate to severe pain, including postoperative pain and ... lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and …
Matched Mixtures name: … Meperidine Hydrochloride and Promethazine Hydrochloride ... Meperidine Hcl and Promethazine Hcl …
Matched Salts name: … Meperidine hydrochloride …
Matched Categories: … pethidine and antispasmodics …
Matched Products: … Meperidine Hydrochloride ... Meperidine Hydrochloride Injection USP ... DBL PETHIDINE HYDROCHLORIDE INJECTION BP 50mg/ml …
Displaying drugs 501 - 525 of 732 in total