Displaying drugs 526 - 550 of 2644 in total
Artemether
Artemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of Plasmodium spp. and may be used to treat infections caused by P. falciparum and unidentified Plasmodium species, including...
Approved
Matched Synonyms: … }.0^{8,13}]hexadecane ... (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13 ... 10-methoxy-1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13 …
Matched Iupac: … }.0^{8,13}]hexadecane ... (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13 …
Matched Iupac: … }.0^{8,13}]hexadecane ... (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13 …
Lauric acid
Lauric acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations of melting-point depression. Lauric acid is a solid at room temperature but melts easily in boiling water, so liquid lauric acid can be treated with various solutes and used to determine their molecular masses.
Approved
Experimental
Matched Synonyms: … C12:0 …
Plasma protein fraction (human)
The plasma protein fraction human (PPFh) is defined as a sterile solution of proteins composed mainly of albumin and globulin derived from human plasma. It is already reviewed under the category of biologics by the FDA where the processing, required tests, requirements and labeling are incorporated. This biologic should come...
Approved
Matched Products: … Octaplas SD Blutgruppe 0 zur Infusion …
Lanolin
Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments .
Lanolin is the purified, secreted...
Approved
Matched Products: … Smartchoices Lanolin Plus 0 …
Metoprolol
Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.[A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date,...
Approved
Investigational
Matched Salts cas: … 119637-66-0 …
Matched Products: … ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL ,10 AMPUL ... METOPROLOL ABZ 0.K. 50MG ... METOPROLOL ABZ 0.K. 100MG …
Matched Products: … ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL ,10 AMPUL ... METOPROLOL ABZ 0.K. 50MG ... METOPROLOL ABZ 0.K. 100MG …
Dronabinol
Dronabinol (marketed as Marinol) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana). THC demonstrates its effects through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, which results in the well-known effects of smoking cannabis such as increased appetite, reduced pain, and...
Approved
Illicit
Matched Synonyms: … delta-9-THC ... delta(9)-THC ... delta-9-tetrahydrocannabinol …
Matched Description: … Dronabinol (marketed as Marinol) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary …
Matched Description: … Dronabinol (marketed as Marinol) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary …
Diacerein
Diacerein is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including severe diarrhea . Diacerein is under investigation for the treatment of Insulin Resistance, Diabetes Mellitus (Type 2),...
Approved
Investigational
Matched Iupac: … 4,5-bis(acetyloxy)-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid …
Epirubicin
An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Approved
Matched Synonyms: … 5,12-NAPHTHACENEDIONE, 10-((3-AMINO-2,3,6-TRIDEOXY-.ALPHA. ... (1S,3S)-3-GLYCOLOYL-1,2,3,4,6,11-HEXAHYDRO-3,5,12-TRIHYDROXY-10-METHOXY-6,11-DIOXO-1-NAPHTHACENYL 3-AMINO …
Matched Iupac: … (8S,10S)-10-{[(2R,4S,5R,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl …
Matched Description: … An anthracycline which is the 4'-epi-isomer of doxorubicin. …
Matched Products: … 4-EPEEDO-10 ... Farmorubicin 10 mg Stechampulle ... มัยซิน ชนิดฉีด (10 มก./5มล.) …
Matched Iupac: … (8S,10S)-10-{[(2R,4S,5R,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl …
Matched Description: … An anthracycline which is the 4'-epi-isomer of doxorubicin. …
Matched Products: … 4-EPEEDO-10 ... Farmorubicin 10 mg Stechampulle ... มัยซิน ชนิดฉีด (10 มก./5มล.) …
Ibrexafungerp
Ibrexafungerp, also known as SCY-078 or MK-3118, is a novel enfumafungin derivative oral triterpene antifungal approved for the treatment of vulvovaginal candidiasis (VVC), also known as a vaginal yeast infection.[A235384,L34349] It was developed out of a need to treat fungal infections that may have become resistant to echinocandins or azole...
Approved
Investigational
Matched Iupac: … {2,11}.0^{5,10}]henicos-2-ene-6-carboxylic acid ... 2R)-3-methylbutan-2-yl]-20-[5-(pyridin-4-yl)-1H-1,2,4-triazol-1-yl]-17-oxapentacyclo[13.3.3.0^{1,14}.0^ …
Matched Salts cas: … 1965291-08-0 …
Matched Salts cas: … 1965291-08-0 …
Orciprenaline
A beta-adrenergic agonist used in the treatment of asthma and bronchospasms. [PubChem]
Approved
Anthralin
Anthralin (1,8‐dihydroxy‐9anthrone, dithranol) is an older anti-psoriatic agent that was first synthesized as a derivative of chrysarobin, obtained from the araroba tree in Brazil over 100 years ago. Adverse effects of anthralin include irritation and discoloration of the skin .
This specific property of the molecule inspired workers to study...
Approved
Matched Iupac: … 1,8-dihydroxy-9,10-dihydroanthracen-9-one …
Bleomycin
A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin.
Approved
Investigational
Matched Description: … -0). ... glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10 …
Lindane
An organochlorine insecticide that has been used as a pediculicide and a scabicide. Lindane has been banned in California, United Kingdom, Australia, and many western countries due to concerns about neurotoxicity and adverse effects on the environment. In Canada, Lindane is not recommmended as a first-line therapy due to reports...
Approved
Withdrawn
Betibeglogene autotemcel
Betibeglogene autotemcel is an autologous gene therapy that adds functional copies of the β-globin gene (βA-T87Q-globin) to hematopoietic stem cells in order to treat β-thalassemia. β-thalassemia is a condition caused by mutations in the β-globin gene (HBB) that leads to a significant decrease in the production of β-globin. This affects...
Approved
Investigational
Matched Description: … /β0). ... /sup>/β0 genotype) compared to those with no detectable β-globin production (β0 ... autotemcel is more effective in patients with β-thalassemia with residual β-globin synthesis (non-β0< …
Abametapir
Abametapir is a novel pediculicidal metalloproteinase inhibitor used to treat infestations of head lice. The life cycle of head lice (Pediculus capitis) is approximately 30 days, seven to twelve of which are spent as eggs laid on hair shafts near the scalp. Topical pediculicides generally lack adequate ovicidal activity, including...
Approved
Investigational
Matched Description: … including standard-of-care treatments such as [permethrin], and many require a second administration 7-10 …
Pibrentasvir
Pibrentasvir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS5A inhibitor that targets the the viral RNA replication and viron assembly. In combination with DB13879, pibrentastiv is a useful therapy for patients who experienced therapeutic failure from other NS5A inhibitors. In cell cultures, the emergence of amino...
Approved
Investigational
Dezocine
Dezocine is a partial opiate drug and is used for pain management. Dezocine is a very effective alternative to fentanyl when administered during outpatient laparoscopy, although is associated with an increased incidence of postoperative nausea.
Approved
Investigational
Dienogest
Dienogest is an orally-active semisynthetic progestogen which also possesses the properties of 17α-hydroxyprogesterone. It is a derivative of 19-nortestosterone and has antiandrogenic properties. It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is not...
Approved
Matched Synonyms: … 17-alpha-Cyanomethyl-17-beta-hydroxy-estra-4,9(10)-dien-3-one …
Matched Iupac: … 2-[(10S,11S,14R,15S)-14-hydroxy-15-methyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-1,6-dien-14-yl] …
Matched Mixtures name: … VELBIENNE® 10 …
Matched Iupac: … 2-[(10S,11S,14R,15S)-14-hydroxy-15-methyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-1,6-dien-14-yl] …
Matched Mixtures name: … VELBIENNE® 10 …
Sodium bicarbonate
Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Mixtures name: … Prismasol 0 ... Prismasol Bgk2/0 ... Phoxillum B22k4/0 …
Matched Products: … BICARBONATO DE SODIO 10 MEQ / 10 ML ... Sodium Bicarbonate 10 gr ... TÜRKTIPSAN MOLAR SODYUM 840 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ, 10 ADET …
Matched Products: … BICARBONATO DE SODIO 10 MEQ / 10 ML ... Sodium Bicarbonate 10 gr ... TÜRKTIPSAN MOLAR SODYUM 840 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ, 10 ADET …
Levofloxacin
Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones...
Approved
Investigational
Matched Synonyms: … (3S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine ... (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine ... (S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine …
Matched Iupac: … (2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5 …
Matched Salts cas: … 138199-71-0 …
Matched Products: … INFECUR 500 MG FILM TABLET, 10 ADET ... LEBEL 250 MG FILM TABLET, 10 ADET ... LEVOXIMED 250MG FILM KAPLI TABLET , 10 TABLET …
Matched Iupac: … (2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5 …
Matched Salts cas: … 138199-71-0 …
Matched Products: … INFECUR 500 MG FILM TABLET, 10 ADET ... LEBEL 250 MG FILM TABLET, 10 ADET ... LEVOXIMED 250MG FILM KAPLI TABLET , 10 TABLET …
Fluticasone furoate
Fluticasone furoate is a synthetic glucocorticoid available as an inhaler and nasal spray for various inflammatory indications[FDA Label] . Fluticasone furoate was first approved in 2007 .
Approved
Matched Iupac: … (1R,2R,3aS,3bS,5S,9aS,9bR,10S,11aS)-5,9b-difluoro-1-{[(fluoromethyl)sulfanyl]carbonyl}-10-hydroxy-2,9a …
Eslicarbazepine acetate
Eslicarbazepine acetate (ESL) is an anticonvulsant medication approved for use in Europe, the United States and Canada as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conventional therapy. Eslicarbazepine acetate is a prodrug that is rapidly converted to eslicarbazepine, the primary active metabolite in the body....
Approved
Matched Synonyms: … (10S)-10-acetoxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide ... (10S)-5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl acetate …
Matched Iupac: … (9S)-2-carbamoyl-2-azatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,11,13-hexaen-9-yl acetate …
Matched Iupac: … (9S)-2-carbamoyl-2-azatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,11,13-hexaen-9-yl acetate …
Alprostadil
Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men for whom oral treatment...
Approved
Investigational
Matched Synonyms: … 11α,15α-dihydroxy-9-oxo-13-trans-prostenoic acid ... (13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate ... (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid …
Matched Products: … CAVERJECT POWDER FOR INJECTION 10 mcg/ml ... Caverject Dual 10 µg - Zweikammerzylinderampullen ... Caverject 10 µg - Trockenstechampulle mit Lösungsmittelspritze …
Matched Products: … CAVERJECT POWDER FOR INJECTION 10 mcg/ml ... Caverject Dual 10 µg - Zweikammerzylinderampullen ... Caverject 10 µg - Trockenstechampulle mit Lösungsmittelspritze …
DL-Methylephedrine
Methylephedrine is a sympathomimetic amine that appears in various over-the-counter cough and cold medications throughout the world , , . The abuse of methylephedrine-containing medications has been reported in Japan. Methylephedrine is not legally available in the United States, but has been identified in cases of drug abuse .
Approved
Matched International brands: … Methylhoedrin 10% ... Methylephedrine 10% Fuso ... dl-Methylephedrine Hydrochloride 10% Metal …
Matched Salts cas: … 18760-80-0 …
Matched Salts cas: … 18760-80-0 …
Ibritumomab tiuxetan
Indium or yttrium conjugated murine IgG1 kappa monoclonal antibody directed against the CD20 antigen, which is found on the surface of normal and malignant B lymphocytes. Ibritumomab is produced in Chinese hamster ovary cells and is composed of two murine gamma 1 heavy chains of 445 amino acids each and...
Approved
Investigational
Displaying drugs 526 - 550 of 2644 in total