Displaying drugs 526 - 550 of 1799 in total
Cipaglucosidase alfa
Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in GAA. Other types of enzyme replacement therapy for the treatment of Pompe disease include alglucosidase alfa and avalglucosidase alfa. Cipaglucosidase...
Approved
Investigational
Matched Synonyms: … Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphate …
Matched Description: … alfa] and [avalglucosidase alfa]. ... ,[L45275] and the EMA fully approved the drug on March 27, 2023. ... mannose-6-phosphate receptor (CI-MPR) in skeletal muscle, one of the main affected tissues in Pompe …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Description: … alfa] and [avalglucosidase alfa]. ... ,[L45275] and the EMA fully approved the drug on March 27, 2023. ... mannose-6-phosphate receptor (CI-MPR) in skeletal muscle, one of the main affected tissues in Pompe …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Mometasone furoate
Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295]. It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and higher than many other corticosteroids as well . Mometasone furoate is formulated as a dry powder...
Approved
Investigational
Vet approved
Matched Synonyms: … Mometasone furoate anhydrous …
Matched Description: … Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and ... Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different ... It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than …
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 2% / Mometasone Furoate 0.1% / Niacinamide 4% …
Matched Categories: … formoterol and mometasone ... Corticosteroids for inhalation use ... Drugs for Obstructive Airway Diseases …
Matched Products: … Nasonex Allergy and Congestion ... Up and Up Allergy ... Nasal Allergy and Congestion Relief …
Matched Description: … Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and ... Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different ... It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than …
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 2% / Mometasone Furoate 0.1% / Niacinamide 4% …
Matched Categories: … formoterol and mometasone ... Corticosteroids for inhalation use ... Drugs for Obstructive Airway Diseases …
Matched Products: … Nasonex Allergy and Congestion ... Up and Up Allergy ... Nasal Allergy and Congestion Relief …
2-phospho-D-glyceric acid
A 2-phosphoglyceric acid in which the glyceric acid moiety has D (R) configuration.
Experimental
Matched Synonyms: … D-glycerate 2-phosphate …
Bleomycin
A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin.
Approved
Investigational
Matched Description: … It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. ... of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and ... Bleomycin A2 is used as the representative structure for Bleomycin. …
Matched Salts name: … Bleomycin sulfate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … BIXEL (BLEOMYCIN SULPHATE FOR INJECTION 15 UNITS) ... DBL BLEOMYCIN SULFATE FOR INJECTION 15000 iu/vial ... DBL™ BLEOMYCIN SULFATE FOR INJECTION 15 units …
Matched Salts name: … Bleomycin sulfate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … BIXEL (BLEOMYCIN SULPHATE FOR INJECTION 15 UNITS) ... DBL BLEOMYCIN SULFATE FOR INJECTION 15000 iu/vial ... DBL™ BLEOMYCIN SULFATE FOR INJECTION 15 units …
Dexmedetomidine
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Approved
Vet approved
Matched Description: … An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and …
Matched Categories: … Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Dexmedetomidine Hydrochloride in Sodium Chloride ... Dexmedetomidine Hydrochloride In 0.9% Sodium Chloride ... PRECEDEX™ IN 0.9% SODIUM CHLORIDE INJECTION 4MCG/ML …
Matched Categories: … Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Dexmedetomidine Hydrochloride in Sodium Chloride ... Dexmedetomidine Hydrochloride In 0.9% Sodium Chloride ... PRECEDEX™ IN 0.9% SODIUM CHLORIDE INJECTION 4MCG/ML …
Cytidine 3'-monophosphate
Experimental
Matched Synonyms: … Cytidine 3'-phosphate …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
alpha-D-glucose 6-phosphate
Experimental
Matched Synonyms: … alpha-D-Glucopyranose 6-phosphate …
Matched Name: … alpha-D-glucose 6-phosphate …
Matched Name: … alpha-D-glucose 6-phosphate …
Magnesium hydroxide
Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form.
Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used commercially...
Approved
Investigational
Matched Synonyms: … Milk of magnesia ... Magnesio hidróxido ... Magnesii hydroxidum …
Matched Name: … Magnesium hydroxide …
Matched Iupac: … magnesium(2+) dihydroxide …
Matched Description: … Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used ... tablet form. ... It can also be used topically as a deodorant or for the relief of canker sores (aphthous ulcers). …
Matched Mixtures name: … Omeprazole, Sodium Bicarbonate, Magnesium Hydroxide ... Omeprazole, Sodium Bicarbonate, Magnesium Hydroxide ... Calcium Carbonate, Magnesium Hydroxide …
Matched Categories: … Aluminum and magnesium containing antacids ... Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... Antacids and Adsorbents ... Basic Ointments and Protectants …
Matched Products: … Milk of Magnesia ... Magnesium Hydroxide ... MAGNESIA …
Matched Name: … Magnesium hydroxide …
Matched Iupac: … magnesium(2+) dihydroxide …
Matched Description: … Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used ... tablet form. ... It can also be used topically as a deodorant or for the relief of canker sores (aphthous ulcers). …
Matched Mixtures name: … Omeprazole, Sodium Bicarbonate, Magnesium Hydroxide ... Omeprazole, Sodium Bicarbonate, Magnesium Hydroxide ... Calcium Carbonate, Magnesium Hydroxide …
Matched Categories: … Aluminum and magnesium containing antacids ... Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... Antacids and Adsorbents ... Basic Ointments and Protectants …
Matched Products: … Milk of Magnesia ... Magnesium Hydroxide ... MAGNESIA …
Sodium stibogluconate
Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration by injection. It belongs to the class of medicines known as the pentavalent antimonials. Sodium stibogluconate is sold in the UK as Pentostam (manufactured by GlaxoSmithKline). Widespread resistance has limited the utility of sodium stibogluconate,...
Approved
Investigational
Matched Synonyms: … Estibogluconato sodico ... Antimony sodium gluconate ... Sodium stibogluconate …
Matched Name: … Sodium stibogluconate …
Matched Description: … Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration ... Widespread resistance has limited the utility of sodium stibogluconate, and in many parts of the world ... Sodium stibogluconate is sold in the UK as Pentostam (manufactured by GlaxoSmithKline). …
Matched Categories: … sodium stibogluconate ... Agents Against Leishmaniasis and Trypanosomiasis ... Antiparasitic Products, Insecticides and Repellents …
Matched Name: … Sodium stibogluconate …
Matched Description: … Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration ... Widespread resistance has limited the utility of sodium stibogluconate, and in many parts of the world ... Sodium stibogluconate is sold in the UK as Pentostam (manufactured by GlaxoSmithKline). …
Matched Categories: … sodium stibogluconate ... Agents Against Leishmaniasis and Trypanosomiasis ... Antiparasitic Products, Insecticides and Repellents …
Dexpanthenol
Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that...
Approved
Matched Description: … ) and the levorotatory form (levopanthenol) as [DB11204]. ... , such as ointments and lotions for treatment of dermatological conditions to relieve itching or promote ... Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and …
Matched Mixtures name: … Somarexin and C 1000 ... B Complex W C and B12 Inj ... CH6 Perfumed Aloforthya Peony and the sunset …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Vitamin D and Analogues …
Matched Products: … Eros Aqua Sensations and Care Woman …
Matched Mixtures name: … Somarexin and C 1000 ... B Complex W C and B12 Inj ... CH6 Perfumed Aloforthya Peony and the sunset …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Vitamin D and Analogues …
Matched Products: … Eros Aqua Sensations and Care Woman …
beta-D-galactose 6-phosphate
Experimental
Matched Synonyms: … beta-galactose-6-phosphate …
Matched Name: … beta-D-galactose 6-phosphate …
Matched Name: … beta-D-galactose 6-phosphate …
OXI-4503
OXI-4503 is investigated in clinical trials for treating cancer/tumors. OXI-4503 is a solid. OXI-4503 blocks and destroys tumor vasculature, resulting in extensive tumor cell death and necrosis. OXI-4503 (combretastatin A1 di-phosphate / CA1P) is a unique and highly potent, dual-mechanism vascular disrupting agent (VDA). In addition, however, preclinical data demonstrates...
Investigational
Matched Synonyms: … Combretastatin A-1 bis(phosphate) …
Matched Description: … OXI-4503 (combretastatin A1 di-phosphate / CA1P) is a unique and highly potent, dual-mechanism vascular ... OXI-4503 is investigated in clinical trials for treating cancer/tumors. OXI-4503 is a solid. ... OXI-4503 blocks and destroys tumor vasculature, resulting in extensive tumor cell death and necrosis. …
Matched Categories: … Phosphate salts …
Matched Description: … OXI-4503 (combretastatin A1 di-phosphate / CA1P) is a unique and highly potent, dual-mechanism vascular ... OXI-4503 is investigated in clinical trials for treating cancer/tumors. OXI-4503 is a solid. ... OXI-4503 blocks and destroys tumor vasculature, resulting in extensive tumor cell death and necrosis. …
Matched Categories: … Phosphate salts …
ABBV-CLS-7262
Investigational
Matched Synonyms: … phosphate - 2-amino-2- (hydroxymethyl)propane-1,3-diol (1/1/1) ... Sodium ({(2S)-1,4-bis[2-(4-chloro-3- fluorophenoxy)acetamido]bicyclo[2.2.2]octan-2- yl}oxy)methyl hydrogen …
Matched Iupac: … ]bicyclo[2.2.2]octan-2-yl]oxy}methyl hydrogen phosphate ... sodium 2-amino-2-(hydroxymethyl)propane-1,3-diol {[(2S)-1,4-bis[2-(4-chloro-3-fluorophenoxy)acetamido …
Matched Iupac: … ]bicyclo[2.2.2]octan-2-yl]oxy}methyl hydrogen phosphate ... sodium 2-amino-2-(hydroxymethyl)propane-1,3-diol {[(2S)-1,4-bis[2-(4-chloro-3-fluorophenoxy)acetamido …
Hydroxyethyl Starch
Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume.
HES is a general term and can be sub-classified according to average molecular weight, molar substitution, concentration, C2/C6 ratio and Maximum Daily Dose.
Approved
Matched Description: … , concentration, C2/C6 ratio and Maximum Daily Dose. ... HES is a general term and can be sub-classified according to average molecular weight, molar substitution ... Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular …
Matched Mixtures name: … Hydroxyethyl Starch in Sodium Chloride ... NEOHES %6 HES % 0.9 SODYUM KLORÜR İV İNFÜZYON İÇİN ÇÖZELTİ, 500 ML SETLİ ... NEOHES %6 HES % 0.9 SODYUM KLORÜR İV İNFÜZYON İÇİN ÇÖZELTİ, 500 ML SETSİZ …
Matched Categories: … Blood and Blood Forming Organs ... Blood and Related Products ... Blood Substitutes and Perfusion Solutions ... Blood Substitutes and Plasma Protein Fractions …
Matched Products: … Hetastarch in Sodium Chloride ... 6% Hetastarch In 0.9% Sodium Chloride ... Volulyte 6% Solution for Infusion …
Matched Mixtures name: … Hydroxyethyl Starch in Sodium Chloride ... NEOHES %6 HES % 0.9 SODYUM KLORÜR İV İNFÜZYON İÇİN ÇÖZELTİ, 500 ML SETLİ ... NEOHES %6 HES % 0.9 SODYUM KLORÜR İV İNFÜZYON İÇİN ÇÖZELTİ, 500 ML SETSİZ …
Matched Categories: … Blood and Blood Forming Organs ... Blood and Related Products ... Blood Substitutes and Perfusion Solutions ... Blood Substitutes and Plasma Protein Fractions …
Matched Products: … Hetastarch in Sodium Chloride ... 6% Hetastarch In 0.9% Sodium Chloride ... Volulyte 6% Solution for Infusion …
Ivermectin
Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)avermectin A1a (22,23-dihydroavermectin B1b). Ivermectin is mainly used in...
Approved
Investigational
Vet approved
Matched Description: … use for the prophylaxis and treatment of COVID-19. ... Due to a number of factors - for example, the relatively low number of patients per trial and the speed ... _in vitro_ data, and the clinical utility of this data remains unclear. …
Matched Mixtures name: … Eqvalan Duo Oral Paste for Horse ... Heartgard Plus Chewable Tablet for Dogs - 26 - 50 lbs ... Heartgard Plus Chewable Tablet for Dogs - Up to 25 lbs …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides and Pediculicides …
Matched Products: … IVOMEC Injection 1% w/v for Cattle and Sheep ... ECOMECTIN 6 MG/ G PREMIX FOR MEDICATED FEEDING STUFF FOR PIGS -Granules ... Ivomec Premix for Pigs 0.6% w/w …
Matched Mixtures name: … Eqvalan Duo Oral Paste for Horse ... Heartgard Plus Chewable Tablet for Dogs - 26 - 50 lbs ... Heartgard Plus Chewable Tablet for Dogs - Up to 25 lbs …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides and Pediculicides …
Matched Products: … IVOMEC Injection 1% w/v for Cattle and Sheep ... ECOMECTIN 6 MG/ G PREMIX FOR MEDICATED FEEDING STUFF FOR PIGS -Granules ... Ivomec Premix for Pigs 0.6% w/w …
Sodium chlorite
Used as an agent for cleaning drinking water. It is also used as an additive in products like toothpaste and mouthwash. Acidified sodium chlorite was approved by the U.S. Food and Drug Administration as of 2004, as an anti-microbial agent which is non-toxic, but not as a drug [A174811, L5413].
Experimental
Matched Name: … Sodium chlorite …
Matched Iupac: … sodium chlorite …
Matched Description: … Acidified sodium chlorite was approved by the U.S. ... It is also used as an additive in products like toothpaste and mouthwash. ... Food and Drug Administration as of 2004, as an anti-microbial agent which is non-toxic, but not as a …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers ... sodium chlorite ... Chlorine Compounds …
Matched Products: … V Doctor pure chlorine dioxide ... Pube Chlorine Dioxide Disinfection …
Matched Iupac: … sodium chlorite …
Matched Description: … Acidified sodium chlorite was approved by the U.S. ... It is also used as an additive in products like toothpaste and mouthwash. ... Food and Drug Administration as of 2004, as an anti-microbial agent which is non-toxic, but not as a …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers ... sodium chlorite ... Chlorine Compounds …
Matched Products: … V Doctor pure chlorine dioxide ... Pube Chlorine Dioxide Disinfection …
Guanosine-2'-monophosphate
Experimental
Matched Synonyms: … Guanosine 2'-phosphate …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
beta-D-arabinofuranose 5-phosphate
Experimental
Matched Synonyms: … β-D-arabinofuranose 5-phosphate …
Matched Name: … beta-D-arabinofuranose 5-phosphate …
Matched Name: … beta-D-arabinofuranose 5-phosphate …
Silicic acid
Experimental
Matched Synonyms: … Silicon dioxide hydrate ... Hydrated silica ... Silica hydrate …
Matched Name: … Silicic acid …
Matched Categories: … Silicon Compounds …
Matched Name: … Silicic acid …
Matched Categories: … Silicon Compounds …
Panax notoginseng root
Panax notoginseng root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Investigational
Matched Synonyms: … Tienchi Ginseng (Constituent of American Ginseng, Asian Ginseng, and Tienchi Ginseng) …
Ascorbyl phosphate
Ascorbyl phosphate is a synthetic form of Vitamin C and is found in different salt forms such as magnesium ascorbyl phosphate and sodium ascorbyl phosphate. These salts are present in cosmetic products at concentrations ranging from 0.001 % to 3% . As vitamin C is susceptible to breakdown of compound...
Approved
Matched Name: … Ascorbyl phosphate …
Matched Description: … Ascorbyl phosphate is a synthetic form of Vitamin C and is found in different salt forms such as magnesium ... ascorbyl phosphate and sodium ascorbyl phosphate. ... phosphate, along with other Vitamin C derivatives, acts as an active and stable precursor of vitamin …
Matched Salts name: … Magnesium ascorbyl phosphate …
Matched Categories: … Vitamin C and analogues …
Matched Description: … Ascorbyl phosphate is a synthetic form of Vitamin C and is found in different salt forms such as magnesium ... ascorbyl phosphate and sodium ascorbyl phosphate. ... phosphate, along with other Vitamin C derivatives, acts as an active and stable precursor of vitamin …
Matched Salts name: … Magnesium ascorbyl phosphate …
Matched Categories: … Vitamin C and analogues …
Cyclic adenosine monophosphate
Cyclic adenosine monophosphate (cAMP, cyclic AMP or 3'-5'-cyclic adenosine monophosphate) is a molecule that is important in many biological processes; it is derived from adenosine triphosphate (ATP).
Experimental
Matched Synonyms: … Adenosine 3',5'-phosphate ... Adenosine 3',5'-cyclic phosphate …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Chloride ion
Experimental
Matched Synonyms: … Chloride ... Chloride (ion) ... Chloride ions …
Matched Name: … Chloride ion …
Matched Iupac: … chloride …
Matched Categories: … Chlorides ... Chlorine Compounds …
Matched Name: … Chloride ion …
Matched Iupac: … chloride …
Matched Categories: … Chlorides ... Chlorine Compounds …
Coagulation Factor IX Human
Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B.
Approved
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... Octaplex Powder and Solvent for Solution for Infusion ... BERIPLEX P/N 500 POWDER FOR SOLUTION FOR INJECTION …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... coagulation factor IX, II, VII and X in combination …
Matched Products: … IMMUNINE 120IU/ML Powder and solvent for solution for injection or infusion ... REPLENINE-VF 500 FOR INJECTION ... PROFILNINE FOR INJECTION 500 iu/5 ml …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... coagulation factor IX, II, VII and X in combination …
Matched Products: … IMMUNINE 120IU/ML Powder and solvent for solution for injection or infusion ... REPLENINE-VF 500 FOR INJECTION ... PROFILNINE FOR INJECTION 500 iu/5 ml …
Aluminium monostearate
Aluminium monostearate is a salt of stearic acid and aluminium with the molecular formula Al(OH)2C18H35O2. Also known as dihydroxyaluminium or dihydroxy(stearato)aluminium, it is used to form gels in the packaging of pharmaceuticals and in the preparation of colors for cosmetics. While considered safe for use, extensive usage may result in...
Experimental
Matched Synonyms: … Dibasic aluminium stearate ... Dibasic aluminum stearate …
Matched Description: … of pharmaceuticals and in the preparation of colors for cosmetics. ... Aluminium monostearate is a salt of stearic acid and aluminium with the molecular formula Al(OH)2C18H35O2 ... While considered safe for use, extensive usage may result in aluminum accumulation. …
Matched Description: … of pharmaceuticals and in the preparation of colors for cosmetics. ... Aluminium monostearate is a salt of stearic acid and aluminium with the molecular formula Al(OH)2C18H35O2 ... While considered safe for use, extensive usage may result in aluminum accumulation. …
Displaying drugs 526 - 550 of 1799 in total