Displaying drugs 526 - 550 of 15272 in total
Cetrorelix
Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). GnRH controls another hormone that is called luteinizing hormone (LH), which is the hormone that starts ovulation during the menstrual cycle. When undergoing hormone treatment sometimes premature ovulation can occur, leading to eggs that are not...
Approved
Investigational
Matched Iupac: … hydroxyphenyl)propanamido]pentanamido]-4-methylpentanamide ... carbamoyl}pyrrolidin-1-yl]-1-oxopentan-2-yl]-2-[(2R)-5-(carbamoylamino)-2-[(2S)-2-[(2S)-2-[(2R)-2-[(2R)-3-(4- ... acetamido-3-(naphthalen-2-yl)propanamido]propanamido]-3-(pyridin-3-yl)propanamido]-3-hydroxypropanamido]-3-(4- …
Matched Description: … Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). …
Matched Description: … Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). …
Influenza B virus B/Phuket/3073/2013 live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the ... A seasonally-specific component of the influenza vaccine. …
Influenza B virus B/Brisbane/60/2008 live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the ... A seasonally-specific component of the influenza vaccine. …
Lactitol
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from lactose. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. sucrose). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides...
Approved
Investigational
Matched Iupac: … (2S,3R,4R,5R)-4-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}hexane-1,2,3,5,6-pentol …
Matched Description: … Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose ... [A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in ... [A190918] It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Description: … Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose ... [A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in ... [A190918] It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Chromium nicotinate
Approved
Experimental
Treprostinil
Treprostinil is a stable tricyclic analogue of prostacyclin that promotes the vasodilation of pulmonary and systemic arterial vascular beds and the inhibition of platelet aggregation.[L41855,L41860,L41865] It reduces symptoms in patients with pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease.[L41855,L41860] The first agent approved for the treatment...
Approved
Investigational
Matched Description: … Treprostinil was approved by the FDA in 2002 for the treatment of pulmonary arterial hypertension. ... Treprostinil is a stable tricyclic analogue of prostacyclin[A248770] that promotes the vasodilation of ... [L41855,L41860] The first agent approved for the treatment of PAH was [epoprostenol], a synthetic prostacyclin …
Matched Salts cas: … 289480-64-4 …
Matched Salts cas: … 289480-64-4 …
Cefradine
A semi-synthetic cephalosporin antibiotic.
Approved
Matched Description: … A semi-synthetic cephalosporin antibiotic. …
Influenza B virus B/Austria/1359417/2021 live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... These vaccines provide protection from influenza by exposing the immune system to the virus (or parts ... A seasonally-specific component of the influenza vaccine. …
Deflazacort
Deflazacort, also known as Emflaza, is a corticosteroid prodrug used as an agent to manage Duchenne Muscular Dystrophy (DMD). It is marketed by Marathon Pharmaceuticals and was approved in February 2017 by the FDA.[L6694,FDA label]
Duchenne Muscular Dystrophy is an inherited disorder resulting from mutations of the dystrophin gene, which...
Approved
Investigational
Matched Description: … It is marketed by Marathon Pharmaceuticals and was approved in February 2017 by the FDA. ... [A179446,A179449,L6697] This disease usually manifests by muscle weakness in early childhood followed ... Deflazacort, also known as Emflaza, is a corticosteroid prodrug used as an agent to manage Duchenne Muscular …
Corynebacterium diphtheriae
Corynebacterium diphtheriae toxin is extracted from the pathogenic actinobacterium C. diphtheriae that causes diphtheria. The bacteria culture is grown in a medium and through purification, diphtheria toxin is detoxified with formaldehyde and diafiltered. The vaccine is intramuscularly administered to provide active immunization against diphtheria in infants and children.
Approved
Investigational
Matched Description: … The bacteria culture is grown in a medium and through purification, diphtheria toxin is detoxified with ... The vaccine is intramuscularly administered to provide active immunization against diphtheria in infants …
Matched Mixtures name: … Boostrix Injektionssuspension in einer Fertigspritze ... Boostrix Polio - Injektionssuspension in einer Fertigspritze ... Menjugate 10 Mikrogramm Injektionssuspension in einer Fertigspritze …
Matched Mixtures name: … Boostrix Injektionssuspension in einer Fertigspritze ... Boostrix Polio - Injektionssuspension in einer Fertigspritze ... Menjugate 10 Mikrogramm Injektionssuspension in einer Fertigspritze …
Vemurafenib
Vemurafenib is a competitive kinase inhibitor with activity against BRAF kinase with mutations like V600E. It exerts its function by binding to the ATP-binding domain of the mutant BRAF. Vemurafenib was co-developed by Roche and Plexxikon and it obtained its FDA approval on August 17, 2011, under the company Hoffmann...
Approved
Matched Iupac: … N-{3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide …
Matched Description: … After approval, Roche in collaboration with Genentech launched a broad development program. [L1012] ... [A31269] It exerts its function by binding to the ATP-binding domain of the mutant BRAF. ... Vemurafenib is a competitive kinase inhibitor with activity against BRAF kinase with mutations like V600E …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Description: … After approval, Roche in collaboration with Genentech launched a broad development program. [L1012] ... [A31269] It exerts its function by binding to the ATP-binding domain of the mutant BRAF. ... Vemurafenib is a competitive kinase inhibitor with activity against BRAF kinase with mutations like V600E …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Chlorobutanol
Chlorobutanol, or chlorbutol, is an alcohol-based preservative with no surfactant activity . It also elicits sedative-hypnotic and weak local anesthetic actions in addition to antibacterial and antifungal properties. Similar in nature to chloral hydrate, it is formed by the simple nucleophilic addition of chloroform and acetone.
As a long-term stabilizer...
Approved
Investigational
Vet approved
Matched Description: … Similar in nature to chloral hydrate, it is formed by the simple nucleophilic addition of chloroform ... Chlorobutanol is a common detergent preservative in eye drops and other ophthalmic therapeutic formulations ... As a long-term stabilizer of multi-ingredient preparations, chlorobutanol is normally used at a concentration …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Apalutamide
Apalutamide is a potent androgen receptor (AR) antagonist that selectively binds to the ligand-binding domain of AR and blocks AR nuclear translocation or binding to androgen response elements . It has been used in trials studying the treatment of Prostate Cancer, Hepatic Impairment, Prostatic Neoplasms, Castration-Resistant Prostate Cancer, and Prostatic...
Approved
Investigational
Matched Iupac: … 4-{7-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl}-2 …
Matched Description: … Apalutamide was approved in February 2018 by the FDA as Erleada for the treatment of patients with non-metastatic ... In mice bearing human CRPC xenograft models, apalutamide treatment produced tumor regressions in a dose-dependent ... In a phase-2 multicenter open-label study, 89% of patients with non-metastatic, castration-resistant …
Matched Description: … Apalutamide was approved in February 2018 by the FDA as Erleada for the treatment of patients with non-metastatic ... In mice bearing human CRPC xenograft models, apalutamide treatment produced tumor regressions in a dose-dependent ... In a phase-2 multicenter open-label study, 89% of patients with non-metastatic, castration-resistant …
Oprelvekin
Oprelvekin, the active ingredient in Neumega®, is recombinant Interleukin-11 (IL-11), which is produced in Escherichia coli (E. coli) by recombinant DNA technology. With a molecular mass of approximately 19,000 daltons, the non-glycosylated protein is 177 amino acids in length in comparison to the natural IL-11, which is 178 amino acid...
Approved
Investigational
Matched Description: … in Escherichia coli (E. coli) by recombinant DNA technology. ... In animal studies, oprelvekin was also shown to regulate intestinal epithelium growth by enhancing healing ... With a molecular mass of approximately 19,000 daltons, the non-glycosylated protein is 177 amino acids …
Magnesium hydroxide
Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form.
Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used commercially...
Approved
Investigational
Matched Description: … Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable ... It can also be used topically as a deodorant or for the relief of canker sores (aphthous ulcers). ... magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used commercially as a …
Matched Mixtures name: … Neo Tigol Tab ... One-A-day Advance Men's ... Maalox oral suspension in sachet …
Matched Mixtures name: … Neo Tigol Tab ... One-A-day Advance Men's ... Maalox oral suspension in sachet …
Misoprostol
Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions.[L7616,L7619,A181589,A181583,A181697] The stimulation of prostaglandin receptors in the stomach reduces gastric acid secretion, while stimulating these receptors in the uterus and cervix can increase the...
Approved
Matched Iupac: … methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(1E)-4-hydroxy-4-methyloct-1-en-1-yl]-5-oxocyclopentyl]heptanoate …
Matched Description: … Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages ... gastric acid secretion, while stimulating these receptors in the uterus and cervix can increase the ... [L7616,L7619,A181589,A181583,A181697] The stimulation of prostaglandin receptors in the stomach reduces …
Matched Description: … Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages ... gastric acid secretion, while stimulating these receptors in the uterus and cervix can increase the ... [L7616,L7619,A181589,A181583,A181697] The stimulation of prostaglandin receptors in the stomach reduces …
Elbasvir
Elbasvir is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, an infectious liver disease caused by infection with hepatitis C virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in...
Approved
Matched Description: … Approved in January 2016 by the FDA, Zepatier is indicated for the treatment of HCV genotypes 1 and 4 ... [A19626]
In a computational target-based drug repurposing investigation published in April 2020, elbasvir ... 1 and 97% and 100% for genotype 4 after 12 weeks of treatment. …
Vericiguat
Vericiguat is a direct stimulator of soluble guanylate cyclase (sGC) used in the management of systolic heart failure to reduce mortality and hospitalizations. A key component of the NO-sGC-cGMP signaling pathway that helps to regulate the cardiovascular system, sGC enzymes are intracellular enzymes found in vascular smooth muscle cells (amongst...
Approved
Investigational
Matched Description: … [L31178]
Vericiguat was approved by the FDA in January 2021 - developed by Merck under the brand name ... by nitric oxide (NO). ... Vericiguat is a direct stimulator of soluble guanylate cyclase (sGC) used in the management of systolic …
Matched Categories: … Vasodilators Used in Cardiac Diseases …
Matched Categories: … Vasodilators Used in Cardiac Diseases …
Glutamic acid
A peptide that is a homopolymer of glutamic acid.
Approved
Nutraceutical
Matched Description: … A peptide that is a homopolymer of glutamic acid. …
Matched Mixtures name: … Aminosyn II in Dextrose ... Aminosyn II in Dextrose ... Aminosyn II in Dextrose …
Matched Mixtures name: … Aminosyn II in Dextrose ... Aminosyn II in Dextrose ... Aminosyn II in Dextrose …
Desonide
A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses.
Approved
Investigational
Matched Description: … A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses. …
Matched Mixtures name: … PRECORT-A KREM ... PRECORT-A POMAD ... PREDNOL-A 30 GR KREM …
Matched Mixtures name: … PRECORT-A KREM ... PRECORT-A POMAD ... PREDNOL-A 30 GR KREM …
Crisaborole
Crisaborole is a novel oxaborole approved by FDA on December 14, 2016 as Eucrisa, a topical treatment of for mild to moderate atopic dermatitis.
This non-steroidal agent is efficacious in improving disease severity, reducing the risk of infection and reducing the signs and symptoms in patients 2 years old and...
Approved
Investigational
Matched Iupac: … 4-[(1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)oxy]benzonitrile …
Matched Description: … Crisaborole is a novel oxaborole approved by FDA on December 14, 2016 as Eucrisa, a topical treatment ... of the phosphodiesterase 4 enzyme. ... It reduces the local inflammation in the skin and prevents further exacerbation of the disease with a …
Matched Categories: … Phosphodiesterase 4 Inhibitors …
Matched Description: … Crisaborole is a novel oxaborole approved by FDA on December 14, 2016 as Eucrisa, a topical treatment ... of the phosphodiesterase 4 enzyme. ... It reduces the local inflammation in the skin and prevents further exacerbation of the disease with a …
Matched Categories: … Phosphodiesterase 4 Inhibitors …
Tyloxapol
Tyloxapol is a non-ionic detergent often used as a surfactant.
Approved
Investigational
Matched Description: … Tyloxapol is a non-ionic detergent often used as a surfactant. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Pentastarch
Pentastarch is an artificial colloid (hydroxyethyl starch derivative). Pentastarch is characterized by presenting five hydroxyethyl groups, which signifies an approximate 50% hydroxyethylation. It is sold under the name Pentaspan by Bristol-Myers Squibb and is used for fluid resuscitation. When administered, pentastarch remains mainly in the circulatory system and hence, it...
Approved
Investigational
Matched Description: … When administered, pentastarch remains mainly in the circulatory system and hence, it is considered a ... It is sold under the name Pentaspan by Bristol-Myers Squibb and is used for fluid resuscitation. ... Pentastarch is characterized by presenting five hydroxyethyl groups, which signifies an approximate 50% …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Boric acid
Boric acid, also known as hydrogen borate, is a weak monobasic Lewis acid of boron with the chemical formula H3BO3. Boric acid is typically utilized in industrial processing and manufacturing, but is also used as an additive in pharmaceutical products, cosmetics, lotions, soaps, mouthwash, toothpaste, astringents, and eyewashes . It...
Approved
Matched Description: … Boric acid, also known as hydrogen borate, is a weak monobasic Lewis acid of boron with the chemical ... in pharmaceutical products, cosmetics, lotions, soaps, mouthwash, toothpaste, astringents, and eyewashes ... Boric acid is typically utilized in industrial processing and manufacturing, but is also used as an additive …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 526 - 550 of 15272 in total