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Displaying drugs 551 - 575 of 6754 in total
Casimersen
Duchenne muscular dystrophy (DMD) is an X-linked recessive allelic disorder characterized by a lack of functional dystrophin protein, which leads to progressive impairment of ambulatory, pulmonary, and cardiac function and is invariably fatal. A related, albeit a less severe, form of muscular dystrophy known as Becker muscular dystrophy (BMD) is...
Approved
Investigational
Lenacapavir
HIV/AIDS remains an area of concern despite the introduction of numerous successful therapies, mainly due to the emergence of multidrug resistance and patient difficulty in adhering to treatment regimens.[A244170, A244175] Lenacapavir is a first-in-class capsid inhibitor that demonstrates picomolar HIV-1 inhibition as a monotherapy in vitro, little to no cross-resistance...
Approved
Investigational
Matched Iupac: … N-[(1S)-1-{3-[4-chloro-3-methanesulfonamido-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl]-6-(3-methanesulfonyl ... -3-methylbut-1-yn-1-yl)pyridin-2-yl}-2-(3,5-difluorophenyl)ethyl]-2-[(2S,4R)-5,5-difluoro-9-(trifluoromethyl …
Matched Salts cas: … 2283356-12-5 …
Matched Salts cas: … 2283356-12-5 …
Sapropterin
Sapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide. It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of tryptophan to 5-hydroxytryptophan via tryptophan hydroxylase.
Approved
Investigational
Matched Synonyms: … 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)-pteridinone ... (−)-(6R)-2-amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(3H)-pteridinone …
Matched Iupac: … (6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-3,4,5,6,7,8-hexahydropteridin-4-one …
Matched Description: … conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of tryptophan to 5- ... It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase …
Matched Iupac: … (6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-3,4,5,6,7,8-hexahydropteridin-4-one …
Matched Description: … conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of tryptophan to 5- ... It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase …
Fludarabine
Fludarabine is a chemotherapeutic agent used in the treatment of hematological malignancies. It is commonly marketed under the brand name Fludara.
Approved
Matched Iupac: … (2R,3S,4S,5R)-2-(6-amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Salts cas: … 75607-67-9 …
Matched Categories: … DNA (Cytosine-5-)-Methyltransferases, antagonists & inhibitors …
Matched Products: … FLUDARA 50 MG IV ENJEKSİYONLUK VEYA İNFÜZYONLUK ÇÖZELTİ TOZU, 5 ADET ... DARABIN 50 MG IV ENJEKSIYON/INFÜZYON ICIN LIYOFILIZE TOZ IÇEREN FLAKON ,5 FLAKON …
Matched Salts cas: … 75607-67-9 …
Matched Categories: … DNA (Cytosine-5-)-Methyltransferases, antagonists & inhibitors …
Matched Products: … FLUDARA 50 MG IV ENJEKSİYONLUK VEYA İNFÜZYONLUK ÇÖZELTİ TOZU, 5 ADET ... DARABIN 50 MG IV ENJEKSIYON/INFÜZYON ICIN LIYOFILIZE TOZ IÇEREN FLAKON ,5 FLAKON …
Chromium Cr-51
Chromium Cr-51 is an isotope of chromium that has been used as a radioactive label for decades. It is used as a diagnostic radiopharmaceutical agent in nephrology to determine glomerular filtration rate,[A249765,A249770] and in hematology to determine red blood cell volume or mass, study the red blood cell survival time...
Approved
Matched Salts cas: … 27849-89-4 …
Sodium chloride
Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed...
Approved
Vet approved
Matched Mixtures name: … ดี-5-1/4เอส ... DEXTROSE 5 % IN 1/4 STR. SALINE ... DEXTROSE 5% IN 1/4 NORMAL SALINE …
Matched Products: … Of Nacl .9% ... BIO NASAL O.9% ... CLORURO DE SODIO 9 MG / ML …
Matched Products: … Of Nacl .9% ... BIO NASAL O.9% ... CLORURO DE SODIO 9 MG / ML …
Calcifediol
The major circulating metabolite of vitamin D3 (cholecalciferol). It is produced in the liver and is the best indicator of the body's vitamin D stores. It is effective in the treatment of rickets and osteomalacia, both in azotemic and non-azotemic patients. Calcifediol also has mineralizing properties.
Approved
Nutraceutical
Matched Iupac: … ]ethylidene}-4-methylidenecyclohexan-1-ol ... (1S,3Z)-3-{2-[(1R,3aS,4E,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene …
Picosulfuric acid
Picosulfuric acid is found in laxative products. Sodium picosulfate is a used to treat constipation or induce colon cleansing to prepare the large bowels before colonoscopy or surgery. The combination product containing sodium picosulfate and magnesium citrate was introduced to the Canadian market in 2005 and has been used in...
Approved
Matched Iupac: … {4-[(pyridin-2-yl)[4-(sulfooxy)phenyl]methyl]phenyl}oxidanesulfonic acid …
Thiamine
Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays...
Approved
Investigational
Nutraceutical
Vet approved
Matched Iupac: … 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium …
Matched Salts cas: … 532-43-4 …
Matched Mixtures name: … Mvc 9+4 Inj ... Mvc 9 Plus 3 Inj ... Pregvit Folic 4 …
Matched Products: … VI-PLEX B1 250 MG/2 ML AMPUL, 5 ADET …
Matched Salts cas: … 532-43-4 …
Matched Mixtures name: … Mvc 9+4 Inj ... Mvc 9 Plus 3 Inj ... Pregvit Folic 4 …
Matched Products: … VI-PLEX B1 250 MG/2 ML AMPUL, 5 ADET …
Alirocumab
Alirocumab is a biopharmaceutical that obtained FDA approval in July 2015 as a second line treatment for high cholesterol in adults whose LDL-cholesterol (LDL-C) is not controlled by the combination of diet and statin treatment. It is a human monoclonal antibody part of the family of the PCSK9 inhibitors which...
Approved
Matched Categories: … Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) Inhibitors …
Nedosiran
Nedosiran is an RNA interference targeting hepatic lactate dehydrogenase, the enzyme responsible for the conversion of glyoxylate to oxalate. Oxalate, particularly calcium oxalate, precipitation is the main cause of kidney stones formation; therefore, blocking the production of oxalate can help alleviate renal symptoms. Nedosiran was approved by the FDA on...
Approved
Investigational
Matched Description: … October 2nd, 2023, under the brand name RIVFLOZA to lower urinary oxalate levels in children 9 …
Inclisiran
Inclisiran is a long-acting, synthetic small interfering RNA (siRNA) directed against proprotein convertase subtilisin-kexin type 9 (PCSK9), which is a serine protease that regulates plasma low-density lipoprotein cholesterol (LDL-C) levels. By binding to PCSK9 messenger RNA, inclisiran prevents protein translation of PCSK9, leading to decreased concentrations of PCSK9 and plasma...
Approved
Investigational
Matched Description: … synthetic small interfering RNA (siRNA) directed against proprotein convertase subtilisin-kexin type 9 …
Matched Categories: … Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) Inhibitors …
Matched Categories: … Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) Inhibitors …
Pilocarpine
A naturally occurring alkaloid derived from the Pilocarpus plants, pilocarpine is a muscarinic acetylcholine agonist.[A262016, A262036] Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors. Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated intraocular pressure and glaucoma. The usage of glaucoma by...
Approved
Investigational
Matched Synonyms: … 2(3H)-FURANONE, 3-ETHYLDIHYDRO-4-((1-METHYL-1H-IMIDAZOL-5-YL)METHYL)-, (3S-CIS)- …
Matched Iupac: … (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]oxolan-2-one …
Matched Mixtures name: … Timpilo 4 ... E-pilo-4 Oph Soln ... E-pilo 4 Ophthalmic Solution …
Matched Products: … PİLOKARSOL % 4 GÖZ DAMLASI, 5 ML ... PILOSED % 4 GOZ DAMLASI, 5 ML ... PILOPTIK %4 STERIL GOZ DAMLASI, 5 ML …
Matched Iupac: … (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]oxolan-2-one …
Matched Mixtures name: … Timpilo 4 ... E-pilo-4 Oph Soln ... E-pilo 4 Ophthalmic Solution …
Matched Products: … PİLOKARSOL % 4 GÖZ DAMLASI, 5 ML ... PILOSED % 4 GOZ DAMLASI, 5 ML ... PILOPTIK %4 STERIL GOZ DAMLASI, 5 ML …
Opicapone
Opicapone is a potent, reversible, and peripherally-acting third-generation inhibitor of catechol-o-methyltransferase (COMT), an enzyme involved in the breakdown of various catecholamines including dopamine.[A36938, A203048] Many patients with Parkinson’s disease treated with levodopa plus a dopa decarboxylase (DDC) inhibitor (eg carbidopa) experience motor complications over time, which calls for the management...
Approved
Investigational
Matched Iupac: … 2,5-dichloro-3-[5-(3,4-dihydroxy-5-nitrophenyl)-1,2,4-oxadiazol-3-yl]-4,6-dimethylpyridin-1-ium-1-olate …
Dihydroergocristine
Dihydroergocristine is part of the ergoloid mixture products. It is a semisynthetic ergot alkaloid and thus, it is characterized by a structural skeleton formed by an alkaloid ergoline. To know more about ergoloid mixtures, please visit DB01049.
Approved
Experimental
Matched Iupac: … -4-carboxamide ... (2R,4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-5,8-dioxo-4-(propan-2-yl)-3-oxa-6,9-diazatricyclo[7.3.0.0 ... ^{2,6}]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14-tetraene …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Cocarboxylase
The coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.
Approved
Experimental
Matched Iupac: … 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(hydrogen phosphonatooxy)(hydroxy)phosphoryl]oxy}ethyl ... )-4-methyl-1,3-thiazol-3-ium …
Matched Salts cas: … 68684-55-9 …
Matched Salts cas: … 68684-55-9 …
Ajmaline
An alkaloid found in the root of Rauwolfia serpentina, among other plant sources. It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials. Ajmaline produces potent sodium channel blocking effects and a very short half-life which makes it a very...
Approved
Experimental
Matched Synonyms: … (5aR,6S,8S,10S,11S,11aS,12aR,13R)-5-methyl-5a,6,8,9,10,11,11a,12-octahydro-5H-6,10:11,12a-dimethanoindolo …
Matched Products: … Gilurytmal 5 mg/ml Injektionslösung und Konzentrat zur Herstellung einer Infusionslösung …
Matched Products: … Gilurytmal 5 mg/ml Injektionslösung und Konzentrat zur Herstellung einer Infusionslösung …
Besilesomab
Besilesomab is a mouse monoclonal antibody labelled with the radioactive isotope technetium-99m for determining the location of inflammation/infection in peripheral bone in adults with suspected osteomyelitis [FDA Label]. Utilised only as a diagnostic agent, besilesomab is currently approved by the EMEA for marketing and use in various European countries like...
Approved
Dexamethasone
Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Developed in 1957, it is structurally similar to other corticosteroids like hydrocortisone and prednisolone. Dexamethasone was granted FDA approval on 30 October 1958....
Approved
Investigational
Vet approved
Matched Description: … Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic …
Matched Salts cas: … 2392-39-4 …
Matched Mixtures name: … NETİZON 5 MG+15 MG/5 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET ... COMBIDEX OFTALMIK SÜSPANSIYON, 5 ML ... COMBİDEX %0.3 + %0.1 GÖZ DAMLASI, ÇÖZELTİ, 5 ML …
Matched Products: … DEKORT 5 MG/5 ML GÖZ VE KULAK DAMLASI, ÇÖZELTİ, 5 ML ... INTHESA-5 ... เด็กซาโม-5 …
Matched Salts cas: … 2392-39-4 …
Matched Mixtures name: … NETİZON 5 MG+15 MG/5 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET ... COMBIDEX OFTALMIK SÜSPANSIYON, 5 ML ... COMBİDEX %0.3 + %0.1 GÖZ DAMLASI, ÇÖZELTİ, 5 ML …
Matched Products: … DEKORT 5 MG/5 ML GÖZ VE KULAK DAMLASI, ÇÖZELTİ, 5 ML ... INTHESA-5 ... เด็กซาโม-5 …
Human papillomavirus type 31 L1 capsid protein antigen
Human papillomavirus type 31 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 31. The vaccine is prepared from the purified...
Approved
Matched Description: … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused …
Matched Mixtures name: … Gardasil 9 ... Gardasil 9 ... Gardasil 9 …
Matched Mixtures name: … Gardasil 9 ... Gardasil 9 ... Gardasil 9 …
Human papillomavirus type 45 L1 capsid protein antigen
Human papillomavirus type 45 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 45. The vaccine is prepared from the purified...
Approved
Matched Description: … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused …
Matched Mixtures name: … Gardasil 9 ... Gardasil 9 ... Gardasil 9 …
Matched Mixtures name: … Gardasil 9 ... Gardasil 9 ... Gardasil 9 …
Human papillomavirus type 52 L1 capsid protein antigen
Human papillomavirus type 52L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 52 The vaccine is prepared from the purified virus-like...
Approved
Matched Description: … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused …
Matched Mixtures name: … Gardasil 9 ... Gardasil 9 ... Gardasil 9 …
Matched Mixtures name: … Gardasil 9 ... Gardasil 9 ... Gardasil 9 …
Human papillomavirus type 18 L1 capsid protein antigen
Human papillomavirus type 18 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Investigational
Matched Description: … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused …
Matched Mixtures name: … Gardasil 9 ... Gardasil 9 ... Gardasil 9 …
Matched Mixtures name: … Gardasil 9 ... Gardasil 9 ... Gardasil 9 …
Iloprost
Iloprost is an analog of prostacyclin (PGI2; epoprostenol), an endogenous prostanoid mainly produced in the vascular endothelium. It is more stable than prostacyclin, which is short-lived. Iloprost consists of a mixture of the 4R and 4S diastereoisomers at a ratio of approximately 53:47. It is a potent vasodilator with reported...
Approved
Investigational
Matched Synonyms: … PENTANOIC ACID, 5-((3AS,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-((1E,3S)-3-HYDROXY-4-METHYL-1-OCTEN-6-YNYL)- ... (5E)-[3aS,4R,5R,6aS)-5-Hydroxy-4-[(1E)-(3S,4RS)-3-hydroxy-4-methyloct-1-en-6-ynyl]-hexahydropentalen- ... (E)-(3aS, 4R, 5R, 6aS)-hexahydro-5-hydroxy-4-[(E)-(3S,4RS) 3-hydroxy-4-methyl-1-octen-6-ynyl]-Δ2(1H) …
Matched Iupac: … 5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-octahydropentalen-2- …
Matched Products: … DIVODIN 20 MCG/ML I.V İNFÜZYONLUK ÇÖZELTİ, 5 ADET ... PULMOLİN 20 MCG/ML IV İNFÜZYONLUK ÇÖZELTİ, 5 ADET ... ILOPERA 20MCG/ML IV INFÜZYON IÇIN ÇÖZELTI IÇEREN AMPUL, 5 ADET …
Matched Iupac: … 5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-octahydropentalen-2- …
Matched Products: … DIVODIN 20 MCG/ML I.V İNFÜZYONLUK ÇÖZELTİ, 5 ADET ... PULMOLİN 20 MCG/ML IV İNFÜZYONLUK ÇÖZELTİ, 5 ADET ... ILOPERA 20MCG/ML IV INFÜZYON IÇIN ÇÖZELTI IÇEREN AMPUL, 5 ADET …
Tiotropium
Tiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma.[A180163,L7084,L7087,L7090,L7093] Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation.[A180163,L7084,L7087,L7090,L7093]
Tiotropium is more specific for the subset of muscarinic receptors commonly found in the...
Approved
Matched Iupac: … ^{2,4}]nonan-9-ium ... (1R,2R,4S,5S,7R)-7-{[2-hydroxy-2,2-bis(thiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.0 …
Matched Salts cas: … 136310-93-5 …
Matched Mixtures name: … ROPITAL 18/4 MCG INHALASYON IÇIN TOZ IÇEREN BLISTER , 60 DOZ ... ROPITAL 18/4 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL , 60 KAPSÜL ... ROPITAL 18/4 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL , 120 KAPSÜL …
Matched Salts cas: … 136310-93-5 …
Matched Mixtures name: … ROPITAL 18/4 MCG INHALASYON IÇIN TOZ IÇEREN BLISTER , 60 DOZ ... ROPITAL 18/4 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL , 60 KAPSÜL ... ROPITAL 18/4 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL , 120 KAPSÜL …
Displaying drugs 551 - 575 of 6754 in total