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Displaying drugs 551 - 575 of 6317 in total
First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control. Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive...
Approved
Matched Iupac: … 3-ethyl-4-methyl-2-oxo-N-(2-{4-[({[(1r,4r)-4-methylcyclohexyl]carbamoyl}amino)sulfonyl]phenyl}ethyl)- ... 2,5-dihydro-1H-pyrrole-1-carboxamide …
Matched Description: … Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by ... useful, cost-effective treatment option for managing type 2 diabetes mellitus. ... used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control. …
Matched Mixtures name: … ILET B GLIMEPIRIDA + METFORMINA CLORHIDRATO 2 MG+500 MG TABLETAS DE LIBERACION PROLONGADA ... GLUCOVEL 1 ... VELACOM PLUS 1/250 …
Matched Products: … DIAPRIDE-1 TABLET 1 mg ... GLUVAS 1 ... VELACOM 1
Boldo leaf extract allergenic extract is used in allergenic testing.
Approved
Experimental
Bisoxatin is a stimulant laxative which increases peristalsis and inhibits absorbtion of water and ions in the intestine . It is marketed in Belgium under the tradename Wylaxine and used for the treatment of constipation and for preparation of the colon for surgical procedures.
Approved
Matched Iupac: … 2,2-bis(4-hydroxyphenyl)-3,4-dihydro-2H-1,4-benzoxazin-3-one …
Matched Description: … Bisoxatin is a stimulant laxative which increases peristalsis and inhibits absorbtion of water and ions …
Approved
Matched Mixtures name: … ZOLBENE CREMA TOPICA (CALAMINA 5% + OXIDO DE ZINC 5% + ALCOHOL BENCILICO 1%) …
A peptide that is a homopolymer of glutamic acid.
Approved
Nutraceutical
Matched Synonyms: … (2S)-2-Aminopentanedioic acid ... (S)-2-Aminopentanedioic acid …
Matched Iupac: … (2S)-2-aminopentanedioic acid …
Matched Description: … A peptide that is a homopolymer of glutamic acid. …
Matched Mixtures name: … Vamin N ... AMINOPLASMAL® B. BRAUN 10% ... AMINOPLASMAL® B. BRAUN 10% …
A preparation of methionine that includes a mixture of D-methionine and L-methionine isomers.
Approved
Experimental
Matched Iupac: … 2-amino-4-(methylsulfanyl)butanoic acid …
Matched Description: … A preparation of methionine that includes a mixture of D-methionine and L-methionine isomers. …
Matched Mixtures name: … Master Key Multi Vitamin Multi Mineral Formula 2 ... AMINOPLASMAL® B. BRAUN 10% ... Extra Once A Day …
Barium sulfate is an inorganic compound with the chemical formula BaSO4 . Barium sulfate occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield . This drug is used as a contrast agent in...
Approved
Matched Iupac: … barium(2+) sulfate …
Matched Description: … This drug is used as a contrast agent in diagnostic x-ray procedures. ... It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … R-X 1 G/ML SÜSPANSİYON ... E.Z.CAT BARYUM SULFAT SUSPANSIYON 1 X 225 ML ... Readi-Cat 2
Belladonna, also known as atropa belladonna or deadly nightshade, is a perennial herbaceous plant in the nightshade family Solanaceae. Its roots, leaves and fruits contain DB00424, DB00747, and mostly, DB00572. These alkaloids are naturally-occurring muscarinic antagonists. DB00572 is a non-selective muscarinic antagonist that is mainly used as an adjunct for...
Approved
Experimental
Matched Description: … Belladonna is a poisonous plant and belladonna intoxication from accidental ingestion may result in a ... Belladonna, also known as atropa belladonna or deadly nightshade, is a perennial herbaceous plant in ... [DB00572] is a non-selective muscarinic antagonist that is mainly used as an adjunct for anaesthesia. …
Phenyl salicylate is a 2-hydroxybenzoic acid phenyl ester. It is utilized in some manufacturing processes of polymers, lacquers, adhesives, waxes, as well as polishes. It is an active ingredient in some pharmaceutical products as a mild analgesic for pain relief by releasing salicylate (found in DB00945 ). Phenyl salicylate may...
Approved
Matched Iupac: … phenyl 2-hydroxybenzoate …
Matched Description: … Phenyl salicylate is a 2-hydroxybenzoic acid phenyl ester. ... Phenyl salicylate is used as a food additive in the USA [L2479]. ... It is an active ingredient in some pharmaceutical products as a mild analgesic for pain relief by releasing …
Matched Mixtures name: … UR N-C Urinary Antiseptic ... UroAv-B ... UroAv-B
Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK) and epidermal growth factor receptor (EGFR). It presents selectivity against the mutant forms of EGFR compared to the wild-type. It also exhibits selectivity against 9 different Crizotinib-resistant mutants of the EML4-ALK fusion gene, which is a...
Approved
Investigational
Matched Iupac: … 5-chloro-N4-[2-(dimethylphosphoryl)phenyl]-N2-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl] …
Matched Description: … Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK ... selectivity against 9 different Crizotinib-resistant mutants of the EML4-ALK fusion gene, which is a ... [A31313] Brigatinib was developed by Ariad Pharmaceuticals, a subsidiary of Takeda Pharmaceutical Company …
Matched Categories: … MATE 2 Inhibitors ... MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Belzutifan is an inhibitor of hypoxia-inducible factor 2α (HIF-2α) used in the treatment of von Hippel-Lindau (VHL) disease-associated cancers. The HIF-2α protein was first identified in the 1990s by researchers at UT Southwestern Medical Center as a key player in the growth of certain cancers. Initially considered to be undruggable,...
Approved
Investigational
Matched Iupac: … 3-{[(1S,2S,3R)-2,3-difluoro-1-hydroxy-7-methanesulfonyl-2,3-dihydro-1H-inden-4-yl]oxy}-5-fluorobenzonitrile …
Matched Description: … spin-off company named Peloton Pharmaceuticals (which itself was eventually acquired by Merck in 2019 ... HIF-2α protein was first identified in the 1990s by researchers at UT Southwestern Medical Center as a ... [L36105] Initially considered to be undruggable, a binding pocket was eventually discovered in the HIF …
Matched Categories: … MATE 2 Inhibitors …
A cyclohexylamido analog of penicillanic acid.
Approved
Matched Synonyms: … -2-carboxylic acid ... (1-aminocyclohexyl)penicillin ... (2S,5R,6R)-6-{[(1-aminocyclohexyl)carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane …
Matched Iupac: … (2S,5R,6R)-6-(1-aminocyclohexaneamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Description: … A cyclohexylamido analog of penicillanic acid. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Indigotindisulfonic acid is a blue-colored dye with a variety of uses.[A32490,A32491,A32492,L2222] Its salt form, indigotindisulfonate sodium, is also known as indigo carmine, indigotine or FD&C Blue #2. This compound is an acid-base indicator and is used in the production of food colorants and pH tests. Indigotindisulfonic acid is used in...
Approved
Investigational
Matched Synonyms: … 2-(1,3-Dihydro-3-oxo-5-sulpho-2H-indol-2-ylidene)-3-oxoindoline-5-sulphonic acid ... FD&C Blue #2
Matched Iupac: … (E)-3,3'-dioxo-1H,1'H,3H,3'H-[2,2'-biindolylidene]-5,5'-disulfonic acid …
Matched Description: … Indigotindisulfonic acid is a blue-colored dye with a variety of uses. ... Its salt form, indigotindisulfonate sodium, is also known as indigo carmine, indigotine or FD&C Blue #2. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Compounds used in a research, industrial, or household setting …
Bromothalonil, also known as Methyldibromo glutaronitrile (MDBGN), is a widely used preservative that can be found in many personal hygiene and industrial products. It is also a known allergen and dermatological irritant that has been banned in many EU countries due to increasing rates of contact allergy . In 2005,...
Approved
Experimental
Matched Synonyms: … 2-Bromo-2-(bromomethyl) glutaronitrile ... 2-Bromo-2-(bromomethyl) pentanedinitrile ... Glutaronitrile, 2-bromo-2-(bromomethyl)- …
Matched Iupac: … 2-bromo-2-(bromomethyl)pentanedinitrile …
Matched Description: … Sensitivity to Bromothalonil may be identified with a clinical patch test. ... Bromothalonil, also known as Methyldibromo glutaronitrile (MDBGN), is a widely used preservative that ... It is also a known allergen and dermatological irritant that has been banned in many EU countries due …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Phenoxymethylpenicillin is a narrow spectrum antibiotic also commonly referred to as Penicillin V or Penicillin VK. It is a phenoxymethyl analog of Penicillin G, or benzylpenicillin. An orally active naturally penicillin, phenoxymethylpenicillin is used to treat mild to moderate infections in the respiratory tract, skin, and soft tissues caused by...
Approved
Vet approved
Matched Synonyms: … (2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1- AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ... (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenoxyacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … [A178609] It is a phenoxymethyl analog of Penicillin G, or [benzylpenicillin]. ... Phenoxymethylpenicillin is a narrow spectrum antibiotic also commonly referred to as Penicillin V or …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Products: … Penstad V 1 Mio. I.E. Tabletten ... Pen-V Genericon 1 Mio. I.E. Filmtabletten ... Penbene 1 Mio. I.E. - Filmtabletten …
Bismuth subgallate is a yellow colored substance that presents as an odorless powder that undergoes discoloration when exposed to sunlight. It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet...
Approved
Matched Iupac: … 2,7-dihydroxy-2H-benzo[d]1,3-dioxa-2-bismacyclopentane-5-carboxylic acid …
Matched Description: … It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. ... Bismuth subgallate is a yellow colored substance that presents as an odorless powder that undergoes discoloration …
Bromperidol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.
Approved
Investigational
Matched Iupac: … 4-[4-(4-bromophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one …
Agalsidase beta is a recombinant human α-galactosidase A similar to agalsidase alfa. While patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater benefit with agalsidase beta.[A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa,...
Approved
Investigational
Matched Description: … Agalsidase beta is a recombinant human α-galactosidase A similar to [agalsidase alfa]. ... While patients generally do not experience a clinically significant difference in outcomes between the ... A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a
Matched Products: … REPLAGAL 1 MG/ML IV İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 ADET ... FABRAZYME 35 MG İNFÜZYONLUK ÇÖZELTİ İÇİN KONSANTRE TOZ, 1 ADET …
A depressor amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
Approved
Investigational
Matched Synonyms: … 2-(4-imidazolyl)ethylamine …
Matched Iupac: … 2-(1H-imidazol-4-yl)ethan-1-amine …
Matched Description: … It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator ... , and also a centrally acting neurotransmitter. ... A depressor amine derived by enzymatic decarboxylation of histidine. …
Matched Salts cas: … 51-74-1
Matched Mixtures name: … Histamine DHCl 0.10 Percent and Menthol 2 Percent …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Butaperazine was approved in 1967 , and possibly discontinued in the 1980s .
Approved
Matched Iupac: … 1-{10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazin-2-yl}butan-1-one …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Benzodiazepine is under investigation for the prevention of Delirium and C.Surgical Procedure; Cardiac. Benzodiazepine has been investigated for the treatment of Obesity, Sleep Apnea, Obstructive, and Disorders of Gallbladder, Biliary Tract and Pancrease.
Approved
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Amiloxate is an EMA-approved chemical UV-filter found in over-the-counter sunscreen products at concentrations up to 10%m . It is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity .
Approved
Matched Synonyms: … 3-(4-Methoxyphenyl)-2-propenoic acid, 3-methylbutyl ester …
Matched Iupac: … 3-methylbutyl (2E)-3-(4-methoxyphenyl)prop-2-enoate …
Matched Description: … Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity [A32916]. …
Approved
Investigational
Matched Iupac: … (1S,2R,10S,11S,13S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵ …
Methylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and Acute Lymphocytic Leukemia, among others.
Approved
Investigational
Matched Iupac: … (1R,3aS,3bS,5S,9aR,9bS,11aS)-1-hydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H, ... 7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-7,10-dione …
Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the...
Approved
Illicit
Investigational
Withdrawn
Matched Iupac: … {1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl}dimethylamine …
Matched Description: … It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule ... markets due to concerns that the drug increases the risk of heart attack and stroke in patients with a
Displaying drugs 551 - 575 of 6317 in total