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Displaying drugs 576 - 600 of 2809 in total
A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop...
Approved
Investigational
Matched Synonyms: … Etacrinic acid ... Etacrynic acid ... Acide étacrynique …
Matched Name: … Etacrynic acid
Matched Iupac: … 2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid
Matched Description: … Henle, but also in the proximal and distal tubules. ... A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of ... This pharmacological action results in excretion of these ions, increased urinary output, and reduction …
Matched Categories: … Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids ... etacrynic acid ... Aryloxyacetic Acid Derivatives …
Matched Products: … Ethacrynic Acid ... Ethacrynic acid
As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like cyclothiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter....
Approved
Matched Synonyms: … 6-chloro-3-(2-norbornen-5-yl)-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide ... 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide ... 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Matched Description: … corticosteroid and estrogen therapy. ... tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and ... indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and
Matched Categories: … Genito Urinary System and Sex Hormones ... cyclothiazide and potassium ... Gynecological Antiinfectives and Antiseptics …
Mycophenolic acid is a potent immunosuppressant agent that inhibits de novo purine biosynthesis. It was derived from Penicillium stoloniferum, and has also shown antibacterial, antifungal and antiviral properties. . Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus)...
Approved
Investigational
Matched Synonyms: … Acido micofenolico ... Mycophenolic acid ... Micofenolico acido
Matched Name: … Mycophenolic acid
Matched Iupac: … (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
Matched Description: … [A249180] However, mycophenolic acid treatment is more expensive and requires therapeutic drug monitoring ... and antiviral properties. ... to optimize efficacy and minimize toxicity. …
Matched Categories: … Mycophenolic Acid and Prodrugs ... Antineoplastic and Immunomodulating Agents ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids
Matched Products: … Mycophenolic Acid ... Apo-mycophenolic Acid ... Mar-mycophenolic Acid
An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Approved
Investigational
Matched Synonyms: … 6-Aminocaproic acid ... Aminocaproic acid ... 6-aminohexanoic acid
Matched Name: … Aminocaproic acid
Matched Iupac: … 6-aminohexanoic acid
Matched Mixtures name: … NAVI Black and C-Clinic ... Relief and Nature Toothpast E Jasmine Mint …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids
Matched Products: … Aminocaproic Acid ... Aminocaproic acid
Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Approved
Investigational
Matched Synonyms: … 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid ... 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ... 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
Matched Iupac: … 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
Matched Description: … [A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration …
Matched Mixtures name: … Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Fluocinolone Acetonide …
Matched Categories: … ciprofloxacin and tinidazole ... ciprofloxacin and ornidazole ... ciprofloxacin and metronidazole ... Drug-Related Side Effects and Adverse Reactions ... Ophthalmological and Otological Preparations …
Matched Products: … Ciprofloxacin and Dextrose ... CILOXAN STERILE OPHTHALMIC AND OTIC SOLUTION 0.3% …
Experimental
Matched Synonyms: … 4-[2-Acetylamino-2-(1-biphenyl-4-ylmethyl-2-oxo-azepan-3-ylcarbamoyl)-ethyl]-2-formyl-benzoic acid
Matched Iupac: … (3S)-1-({[1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-formylbenzoic acid
Hedera helix leaf extract allergenic extract is used in allergenic testing.
Experimental
Matched Synonyms: … Hedera helix leaf
Matched Name: … Hedera helix leaf extract …
Matched Description: … Hedera helix leaf extract allergenic extract is used in allergenic testing. …
Matched Categories: … Cough and Cold Preparations …
A non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-(p-chlorphenyl)-3-methyl-1,3-perhydrothiazin-4-on-1,1-dioxide ... 2-(p-chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one 1,1-dioxide
Matched Categories: … Oxazol, Thiazine, and Triazine Derivatives …
This drug has been developed using Medarex's UltiMAb Human Antibody Development System to treat autoimmune diseases.
Investigational
Matched Name: … NVS antibody
Matched Description: … This drug has been developed using Medarex's UltiMAb Human Antibody Development System to treat autoimmune …
A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … Acidum citricum ... Anhydrous citric acid ... Citric acid,anhydrous …
Matched Name: … Citric acid
Matched Iupac: … 2-hydroxypropane-1,2,3-tricarboxylic acid
Matched Description: … It is an acid compound found in citrus fruits. ... The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability ... Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved …
Matched Mixtures name: … Sodium Citrate and Citric Acid ... Sodium Citrate and Citric Acid ... Sodium Citrate and Citric Acid
Matched Salts name: … Citric acid monohydrate …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Acyclic ... Acid Preparations ... citric acid ... Carboxylic Acids
Matched Products: … Citric Acid ... Citric Acid Wipes …
Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal anti-inflammatory drugs. It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA).[L39065, A255582] Metabolized by intestinal bacteria, sulfasalazine is broken down into mesalazine and sulfapyridine, 2 compounds that carry out the main pharmacological...
Approved
Matched Synonyms: … 2-Hydroxy-5-[4-(pyridin-2-ylsulfamoyl)-phenylazo]-benzoic acid ... 2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid ... 5-(p-(2-Pyridylsulfamyl)phenylazo)salicylic acid
Matched Iupac: … 2-hydroxy-5-[(E)-2-{4-[(pyridin-2-yl)sulfamoyl]phenyl}diazen-1-yl]benzoic acid
Matched Description: … Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal ... It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis ... L39065, A255582] Metabolized by intestinal bacteria, sulfasalazine is broken down into [mesalazine] and
Matched Categories: … Alimentary Tract and Metabolism …
Clesacostat is under investigation in clinical trial NCT04321031 (Metabolic Interventions to Resolve Non-alcoholic Steatohepatitis (NASH) With Fibrosis (MIRNA)).
Investigational
Matched Synonyms: … Benzoic acid, 4-(6-methoxy-4-((1,4,6,7-tetrahydro-1-(1-methylethyl)-7-oxospiro(5h-indazole-5,4'-piperidin ... acid ... -(7-oxo-1-(propan-2-yl)-1,4,6,7-tetrahydrospiro(indazole-5,4'- piperidine)-1'-carbonyl)pyridin-2-yl)benzoic
Investigational
Matched Synonyms: … Benzoic acid, 4-((15-oxoretin-15-yl)amino)- …
Matched Name: … Retinamidic acid
Matched Iupac: … acid ... 4-[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenamido]benzoic
Bumetanide is a sulfamyl diuretic.
Approved
Matched Synonyms: … 3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acid ... 3-butylamino-4-(phenoxy)-5-sulfamoylbenzoic acid ... 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid
Matched Iupac: … 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Genito Urinary System and Sex Hormones ... bumetanide and potassium ... Gynecological Antiinfectives and Antiseptics …
Experimental
Matched Name: … 2-((4'-HYDROXYPHENYL)-AZO)BENZOIC ACID
Matched Iupac: … 2-[(1E)-2-(4-hydroxyphenyl)diazen-1-yl]benzoic acid
Experimental
Matched Name: … 2-((4'-HYDROXYNAPHTHYL)-AZO)BENZOIC ACID
Matched Iupac: … 2-[(1E)-2-(4-hydroxynaphthalen-1-yl)diazen-1-yl]benzoic acid
A narcotic analgesic and antitussive. It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. It is not marketed in the US but is approved for use in various countries around the world. In the US it is a schedule II drug (single-entity) and...
Experimental
Illicit
Matched Synonyms: … Dionine
Matched Description: … A narcotic analgesic and antitussive. ... It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function ... In the US it is a schedule II drug (single-entity) and schedule III drug (in combination products). …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives …
Pinus palustris pollen is the pollen of the Pinus palustris plant. Pinus palustris pollen is mainly used in allergenic testing.
Approved
Matched Name: … Pinus palustris pollen …
Matched Description: … Pinus palustris pollen is the pollen of the Pinus palustris plant. ... Pinus palustris pollen is mainly used in allergenic testing. …
Iocetamic acid is a diagnostic aid (radiopaque medium)
Approved
Matched Synonyms: … Iocetamic acid ... Acido iocetamico ... Acidum iocetamicum …
Matched Name: … Iocetamic acid
Matched Iupac: … 3-[N-(3-amino-2,4,6-triiodophenyl)acetamido]-2-methylpropanoic acid
Matched Description: … Iocetamic acid is a diagnostic aid (radiopaque medium) …
Matched Categories: … iocetamic acid
Experimental
Matched Name: … 4-(Acetylamino)-3-Amino Benzoic Acid
Matched Iupac: … 3-amino-4-acetamidobenzoic acid
Experimental
Matched Name: … 5-Mercapto-2-Nitro-Benzoic Acid
Matched Iupac: … 2-nitro-5-sulfanylbenzoic acid
Investigational
Matched Synonyms: … Lead-212 dotamtate ... Dotamtate lead Pb-212 …
Matched Iupac: … lambda2-(212Pb)lead(2+) 2-[7-({[(1R)-1-{[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(1S,2R)-1-carboxy …
Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly. It is used, in addition to antibiotics...
Approved
Matched Synonyms: … Acetic acid, oxime ... Acetohydroxamic acid ... Acetohydroximic acid
Matched Name: … Acetohydroxamic acid
Matched Description: … Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure ... Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Hydroxy Acids ... Carboxylic Acids ... acetohydroxamic acid
A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of...
Approved
Nutraceutical
Matched Synonyms: … Amber acid ... Acide succinique ... Succinic acid
Matched Name: … Succinic acid
Matched Iupac: … butanedioic acid
Matched Description: … , the manufacture of lacquers, and to make perfume esters. ... It is also used in foods as a sequestrant, buffer, and a neutralizing agent. ... (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical …
Matched Mixtures name: … and Succinic Acid ... Threonate and Succinic Acid ... Iron Aspartate, Glycinate, Ascorbic Calcium, Vitamin B12, Calcium Threonate and Succinic Acid
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids
Experimental
Matched Synonyms: … Hydriodic acid ... Acide iodhydrique ... Acido yodhidrico …
Displaying drugs 576 - 600 of 2809 in total