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Displaying drugs 601 - 625 of 5330 in total
Experimental
Matched Synonyms: … 7-methylguanosine 5'-phosphate ... 7-methylguanosine 5'-(dihydrogen phosphate) …
Matched Name: … 7-methyl-5'-guanylic acid
Matched Iupac: … 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-7-methyl-6-oxo-6,9-dihydro …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleic Acids
Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine...
Approved
Investigational
Matched Iupac: … 4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H-1,3-benzodiazol-2-yl}butanoic acid
Matched Description: … Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks ... (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). ... It is active against both active and quiescent cells, although the exact mechanism of action is unknown …
Matched Salts name: … Bendamustine hydrochloride ... Bendamustine hydrochloride monohydrate …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids, Acyclic ... Carboxylic Acids ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index …
Matched Products: … Bendamustine Hydrochloride ... GENSTINA® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... Bendamustine Hydrochloride for Injection …
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
Approved
Vet approved
Matched Synonyms: … 6-Chloro-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[1,2,4]thiadiazine-7-sulfonic acid amide …
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Salts name: … Chlorothiazide sodium
Matched Categories: … chlorothiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Sodium Chloride Symporter Inhibitors …
Matched Products: … DIURIL Sodium ... Sodium Diuril ... Chlorothiazide Sodium
Trihexyphenidyl is a centrally acting muscarinic antagonist used for treatment of parkinsonism and drug-induced extrapyramidal disorders.[L31773,L31778] Its discovery was published in 1949 in a study looking for drugs with antispasmodic activity. Trihexyphenidyl is rarely used in the treatment of parkinsonism, and is not a first line treatment due to significant...
Approved
Matched International brands: … ACA ... Apo-trihex …
Matched Description: … Trihexyphenidyl is a centrally acting muscarinic antagonist used for treatment of parkinsonism and drug-induced ... [A229103] Trihexyphenidyl is rarely used in the treatment of parkinsonism, and is not a first line treatment ... [L31843] It has largely been replaced by drugs such as [levodopa]. …
Matched Salts cas: … 52-49-3 …
Matched Salts name: … Trihexyphenidyl hydrochloride
Matched Products: … ACA (5 mg.) ... Trihexyphenidyl hydrochloride ... Trihexyphenidyl Hydrochloride
Dicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder and irritable bowel syndrome.[A6556,A182555,A234659,L7967] Though it is commonly prescribed, its recommendation may have been based on a small...
Approved
Matched Synonyms: … Bicyclohexyl-1-carboxylic acid 2-diethylamino-ethyl ester …
Matched Description: … Dicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor ... and irritable bowel syndrome. ... small amount of evidence and so its prescription is becoming less favourable. …
Matched Salts cas: … 67-92-5
Matched Mixtures name: … แอนพัส 520
Matched Salts name: … Dicyclomine hydrochloride
Matched Categories: … Alimentary Tract and Metabolism ... Drugs that are Mainly Renally Excreted ... Acids, Carbocyclic ... Carboxylic Acids ... Cyclohexanecarboxylic Acids
Matched Products: … RELESTAL PEDIATRIC SYRUP 10 mg/5 ml ... Dicyclomine Hydrochloride ... Dicyclomine hydrochloride
Chemically, dantrolene is a hydantoin derivative, but does not exhibit antiepileptic activity like other hydantoin derivates such as phenytoin.
Approved
Investigational
Matched Synonyms: … 1-((5-(p-nitrophenyl)furfurylidene)amino)hydantoin …
Matched Iupac: … 1-[(E)-{[5-(4-nitrophenyl)furan-2-yl]methylidene}amino]imidazolidine-2,4-dione …
Matched Description: … hydantoin derivates such as phenytoin. ... Chemically, dantrolene is a hydantoin derivative, but does not exhibit antiepileptic activity like other …
Matched Salts name: … Dantrolene sodium
Matched Categories: … Dantrolene and Derivatives …
Matched Products: … Dantrolene Sodium ... RYANODEX dantrolene sodium ... Dantrolene Sodium for Injection, USP …
Buspirone is a novel anxiolytic agent with a unique structure and a pharmacological profile. Belonging to the azaspirodecanedione drug class, buspirone is a serotonin 5-HT1A receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates, and other sedative/anxiolytic drugs. Unlike many drugs used to treat anxiety, buspirone does...
Approved
Investigational
Matched Description: … Buspirone is a novel anxiolytic agent with a unique structure and a pharmacological profile. ... , such as generalized anxiety disorder (GAD), and relieve symptoms of anxiety. ... Belonging to the azaspirodecanedione drug class,[A180991] buspirone is a serotonin 5-HT1A
Matched Salts name: … Buspirone hydrochloride
Matched Categories: … Miscellaneous Anxiolytics Sedatives and Hypnotics ... Drugs that are Mainly Renally Excreted …
Matched Products: … Apo-buspirone ... Buspirone Hydrochloride ... BusPIRone Hydrochloride
A commonly used x-ray contrast medium. As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Approved
Vet approved
Matched Synonyms: … Urografin acid ... Diatrizoic acid ... Methalamic acid
Matched Iupac: … 3,5-diacetamido-2,4,6-triiodobenzoic acid
Matched Description: … As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography ... , and urography. ... A commonly used x-ray contrast medium. …
Matched Salts cas: … 737-31-5 ... 50978-11-5
Matched Mixtures name: … Diatrizoate Meglumine and Diatrizoate Sodium ... Diatrizoate Meglumine and Diatrizoate Sodium ... Diatrizoate Meglumine and Diatrizoate Sodium
Matched Salts name: … Diatrizoate sodium ... Diatrizoic acid dihydrate …
Matched Categories: … Drugs that are Mainly Renally Excreted ... Compounds used in a research, industrial, or household setting ... Acids, Carbocyclic ... Carboxylic Acids ... diatrizoic acid
Matched Products: … Hypaque Sodium 50% Liq ... Hypaque Sodium Liq 50% ... Hypaque Sodium 50% - Liq IV …
Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index.[A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of...
Approved
Matched Synonyms: … 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine ... 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine …
Matched Iupac: … 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine …
Matched Description: … , and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic ... A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and ... as an immunosuppressant in the prevention of renal transplant rejection. …
Matched Salts name: … Azathioprine sodium
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors ... Drugs that are Mainly Renally Excreted …
Matched Products: … Azathioprine Sodium ... AZATHIOPRIN ACIS 50MG ... Azathioprine Sodium for Injection …
A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.
Approved
Matched Synonyms: … 1-cyclohexyl-1-phenyl-3-pyrrolidin-1-yl-propan-1-ol hydrochloride
Matched Description: … A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced ... extrapyramidal disorders and in parkinsonism. …
Matched Salts cas: … 1508-76-5
Matched Salts name: … Procyclidine hydrochloride
Matched Products: … Procyclid Tab 5mg ... Kemadrin Tab 5mg
Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label] . Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate .
Approved
Matched Description: … in blood vessels and the prostate[A176837]. ... prostatic hyperplasia and hypertension[FDA Label][A176831]. ... Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign …
Matched Mixtures name: … Hytrin-7 Tabs 1mg-7 Tabs 2mg-14 Tabs 5mg ... Hytrin-7 Tabs 1mg-7 Tabs 2mg-14 Tabs 5mg ... Hytrin-7 Tabs 1mg-7 Tabs 2mg-14 Tabs 5mg
Matched Salts name: … Terazosin hydrochloride ... Terazosin hydrochloride hydrate …
Matched Categories: … Genito Urinary System and Sex Hormones ... Adrenergic alpha-Antagonists ... Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Terazosin Hydrochloride ... Terazosin hydrochloride ... Terazosin Hydrochloride Anhydrous …
Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Synonyms: … quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid ... quinolinyl)ethenyl] phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acid
Matched Iupac: … chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanyl}methyl)cyclopropyl]acetic acid
Matched Description: … has since become available as a generic and as a brand name product. ... [A178651] And although these kinds of effects are currently included in the official prescribing information ... montelukast to elicit neuropsychiatric effects like agitation, hallucinations, suicidal behaviour, and
Matched Mixtures name: … BROCRIPTIN® 10 MG/ 5 MG ... BROCRIPTIN® 5MG/2.5MG ... DESMONT 5/10 MG 90 FILM KAPLI TABLET …
Matched Salts name: … Montelukast sodium
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Products: … Apo-montelukast Sodium ... Apo-montelukast Sodium Chewable ... Spirant 5 Chewable (Montelukast sodium tablets 5 mg) …
Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to...
Approved
Investigational
Matched Synonyms: … 2-methoxy-5-chloroprocainamide ... 2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide ... 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamide …
Matched Iupac: … 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide …
Matched Description: … Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative ... impact on quality of life and poses a significant burden on the healthcare system. ... [A184934] Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated …
Matched Salts cas: … 7232-21-5 ... 54143-57-6 …
Matched Salts name: … Metoclopramide hydrochloride ... Metoclopramide hydrochloride anhydrous …
Matched Categories: … Alimentary Tract and Metabolism ... Benzamides and benzamide derivatives ... Acids, Carbocyclic ... Carboxylic Acids ... Drugs that are Mainly Renally Excreted …
Matched Products: … Apo-metoclop Tab 5mg ... Metoclopramide Hydrochloride ... METOCLOPRAMIDE hydrochloride
Investigational
Matched Synonyms: … VITAMIN A ACETATE C20-D3 …
A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
Approved
Investigational
Vet approved
Matched Synonyms: … Yohimbic acid methyl ester ... 17α-hydroxyyohimban-16α-carboxylic acid methyl ester ... (16α,17α)-17-hydroxyyohimban-16-carboxylic acid methyl ester …
Matched Description: … Yohimbine has been used as a mydriatic and in the treatment of impotence. ... A plant alkaloid with alpha-2-adrenergic blocking activity. ... It is also alleged to be an aphrodisiac. …
Matched Salts name: … Yohimbine hydrochloride
Matched Categories: … Genito Urinary System and Sex Hormones ... Adrenergic alpha-Antagonists ... Adrenergic alpha-2 Receptor Antagonists ... Serotonin 5-HT1 Receptor Antagonists ... Serotonin 5-HT2 Receptor Antagonists …
Matched Products: … Yohimbine Hydrochloride Tab 2mg ... Yohimbine Hydrochloride Tablets 5.4mg ... โปรโคมิล 5 มก. …
Investigational
Matched Synonyms: … Sodium ({(2S)-1,4-bis[2-(4-chloro-3- fluorophenoxy)acetamido]bicyclo[2.2.2]octan-2- yl}oxy)methyl hydrogen ... phosphate - 2-amino-2- (hydroxymethyl)propane-1,3-diol (1/1/1) …
Matched Iupac: … sodium 2-amino-2-(hydroxymethyl)propane-1,3-diol {[(2S)-1,4-bis[2-(4-chloro-3-fluorophenoxy)acetamido ... ]bicyclo[2.2.2]octan-2-yl]oxy}methyl hydrogen phosphate
gamma-Tocopherol is under investigation in clinical trial NCT00836368 (In Vitro Basophil Responsiveness to Allergen Challenge After Gamma-tocopherol Supplementation in Allergic Asthmatics).
Investigational
Matched Synonyms: … D-gamma-Tocopherol
Matched Name: … gamma-Tocopherol
Matched Description: … to Allergen Challenge After Gamma-tocopherol Supplementation in Allergic Asthmatics). ... gamma-Tocopherol is under investigation in clinical trial NCT00836368 (In Vitro Basophil Responsiveness …
Matched Categories: … Diet, Food, and Nutrition ... Tocopherols ... Vitamins ... Vitamin E ... Vitamins (Fat Soluble) …
Experimental
Matched Synonyms: … Ara-5'-CMP ... Aracytidine 5'-phosphate ... Cytosine arabinose-5'-phosphate
Matched Name: … Aracytidine 5'-monophosphate …
Matched Iupac: … acid ... {[(2R,3S,4S,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic …
Fosphenytoin is a water-soluble phenytoin prodrug used only in hospitals for the treatment of epileptic seizures. It works by slowing down impulses in the brain that cause seizures. Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials.
Approved
Investigational
Matched Iupac: … [(2,5-dioxo-4,4-diphenylimidazolidin-1-yl)methoxy]phosphonic acid
Matched Description: … Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium ... channels, and therefore limit repetitive firing of action potentials. ... Fosphenytoin is a water-soluble phenytoin prodrug used only in hospitals for the treatment of epileptic …
Matched Salts name: … Fosphenytoin sodium
Matched Categories: … Phenytoin and Prodrugs ... Sodium Channel Blockers ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index …
Matched Products: … Fosphenytoin Sodium ... Fosphenytoin sodium
Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. It is commonly known as quinalbarbitone in the United Kingdom.
Approved
Vet approved
Matched Synonyms: … 5-allyl-5-(1-methylbutyl)barbituric acid ... 5-allyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione ... 5-(1-methylbutyl)-5-(2-propenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione …
Matched Iupac: … 5-(pentan-2-yl)-5-(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione …
Matched Description: … Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate ... derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. ... It is commonly known as quinalbarbitone in the United Kingdom. …
Matched Salts name: … Secobarbital sodium
Matched Categories: … Hypnotics and Sedatives ... Drugs that are Mainly Renally Excreted …
Matched Products: … Seconal Sodium ... Seconal Sodium Pulvule 240 0.1gm …
Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and cardiogenic shock.[A15638,L33160] Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising...
Approved
Investigational
Matched Description: … well as raising the heart rate and cardiac output, without vasoconstriction. ... [A233724,A233729] The US patent from 1943 states that this compound had a wider therapeutic index and ... anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and
Matched Salts cas: … 51-30-9 ... 6078-56-4 …
Matched Salts name: … Isoprenaline hydrochloride
Matched Categories: … Adrenergic and Dopaminergic Agents ... isoprenaline and other drugs for obstructive airway diseases ... Compounds used in a research, industrial, or household setting …
Matched Products: … Isoproterenol Hydrochloride ... Isoproterenol hydrochloride ... Isuprel Mistometer Aem 0.25% …
Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.
Approved
Matched Synonyms: … L-N-n-propylpipecolic acid-2,6-xylidide …
Matched Description: … It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the ... Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin …
Matched Salts name: … Ropivacaine hydrochloride ... Ropivacaine hydrochloride anhydrous …
Matched Categories: … Drugs that are Mainly Renally Excreted …
Matched Products: … Ropivacaine Hydrochloride ... Ropivacaine hydrochloride ... Ropivacaine Hydrochloride Injection …
Experimental
Matched Synonyms: … Phenyl phosphate ... Phenolic phosphate ... Phenylphosphoric acid
Matched Iupac: … phenoxyphosphonic acid
Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.
Approved
Vet approved
Matched Synonyms: … p-(butylamino)benzoic acid β-(dimethylamino)ethyl ester …
Matched Description: … and patch. ... Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream …
Matched Mixtures name: … Lidocaine and Tetracaine ... Lidocaine and Tetracaine …
Matched Salts name: … Tetracaine hydrochloride
Matched Categories: … Antipruritics and Local Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Acids, Carbocyclic ... Carboxylic Acids ... Esters of Aminobenzoic Acid
Matched Products: … Pontocaine 5 mg/ml ... Supracaine Aem 754mg/65gm ... Pontocaine Pws Inj 20mg/amp
Cyclic adenosine monophosphate (cAMP, cyclic AMP or 3'-5'-cyclic adenosine monophosphate) is a molecule that is important in many biological processes; it is derived from adenosine triphosphate (ATP).
Experimental
Matched Synonyms: … 3',5'-cyclic AMP ... Adenosine 3',5'-phosphate ... Adenosine 3',5'-cyclic phosphate
Matched Description: … Cyclic adenosine monophosphate (cAMP, cyclic AMP or 3'-5'-cyclic adenosine monophosphate) is a molecule ... that is important in many biological processes; it is derived from adenosine triphosphate (ATP). …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Cyclic AMP
Displaying drugs 601 - 625 of 5330 in total