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Displaying drugs 651 - 675 of 11014 in total

Cocaine

An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of...
Approved
Illicit
Matched Description: … It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in ... An alkaloid ester extracted from the leaves of plants including coca. ... its reinforcing effects is thought to involve inhibition of dopamine uptake. …
Matched Categories: … Esters of Benzoic Acid ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Niclosamide

Niclosamide is an antihelminthic used for the treatment of tapeworm infections. Helminths (worms) are multicellular organisms that infect very large numbers of humans and cause a broad range of diseases. Over 1 billion people are infected with intestinal nematodes, and many millions are infected with filarial nematodes, flukes, and tapeworms....
Approved
Investigational
Vet approved
Matched Description: … range of diseases. ... by Bayer in 1996. ... They are an even greater problem in domestic animals. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Etilefrine

Etilefrine is an adrenergic agonist that appears to interact with beta-1 and some alpha-adrenergic receptors. It has been used as a vasoconstrictor agent.
Approved
Withdrawn
Matched Categories: … Compounds used in a research, industrial, or household setting …

Riluzole

A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis. Riluzole is marketed as Rilutek by Sanofi.
Approved
Investigational
Matched Description: … antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Papaverine

An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear,...
Approved
Investigational
Matched Description: … It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, ... An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological ... The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases …
Matched Categories: … Drugs Used in Erectile Dysfunction …

Sulfathiazole

Sulfathiazole is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide. Except for those formulated for vaginal use, the FDA withdrew its approval for the use of...
Approved
Vet approved
Withdrawn
Matched Description: … It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide. ... Except for those formulated for vaginal use, the FDA withdrew its approval for the use of all drug products …
Matched Categories: … combinations of sulfonamides …

Sulfameter

Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections.
Approved
Matched Description: … Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections. …
Matched Categories: … combinations of sulfonamides …

Hydroxocobalamin

Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency. It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia.
Approved
Matched Description: … It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia. ... Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B …

Clomifene

A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Approved
Investigational
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Etacrynic acid

A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop...
Approved
Investigational
Matched Description: … A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of ... This pharmacological action results in excretion of these ions, increased urinary output, and reduction ... in extracellular fluid. …
Matched Categories: … Increased Diuresis at Loop of Henle …

Chorionic Gonadotropin (Human)

Human chorionic gonadotropin (HCG), a polypeptide hormone produced by the human placenta. Endogenously produced HCG interacts with the LHCG receptor of the ovary and promotes the maintenance of the corpus luteum during the beginning of pregnancy. This allows the corpus luteum to continuously secrete the hormone progesterone during the first...
Approved
Vet approved
Matched Description: … human thyroid-stimulating hormone (TSH), while the beta sub­ units of these hormones differ in amino ... In males, HCG also stimulates the production of gonadal steroid hormones by stimulating the interstitial ... of the corpus luteum during the beginning of pregnancy. …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Phenoxyethanol

Phenoxyethanol is a colorless liquid with a pleasant odor. It is a glycol ether used as a perfume fixative, insect repellent, antiseptic, solvent, preservative, and also as an anesthetic in fish aquaculture. Phenoxyethanol is an ether alcohol with aromatic properties. It is both naturally found and manufactured synthetically. Demonstrating antimicrobial...
Approved
Matched Description: … It is very easy to use in various types of formulations and is chemically stable. ... It has also been used in vaccines and shown to inactivate bacteria, and several types of yeast [A32838 ... cosmetic formulations at a maximum concentration of 1.0% [L2625]. …

Amaranthus hybridus pollen

Amaranthus hybridus pollen allergenic extract is used in allergenic testing.
Approved
Matched Description: … Amaranthus hybridus pollen allergenic extract is used in allergenic testing. …

Oteracil

Oteracil is an adjunct to antineoplastic therapy, used to reduce the toxic side effects associated with chemotherapy. Approved by the European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with DB09257 and DB09256 within the commercially available product "Teysuno". The main active ingredient in Teysuno is DB09256,...
Approved
Matched Description: … The main active ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic ... Approved by the European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with ... production of 5-FU. …

Influenza B virus B/Maryland/15/2016 recombinant hemagglutinin antigen

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …

Sulfametopyrazine

Long-acting plasma-bound sulfonamide used for respiratory and urinary tract infections and also for malaria.
Approved
Withdrawn
Matched Categories: … combinations of sulfonamides …

Trichlormethiazide

A thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p830)
Approved
Vet approved
Matched Iupac: … 6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Description: … A thiazide diuretic with properties similar to those of hydrochlorothiazide. …
Matched Categories: … combinations of sulfonamides …

Procaine benzylpenicillin

Procaine benzylpenicillin (INN), also known as procaine G penicillin, is an injectable antiobiotic. It is a poorly soluble salt form of penicillin which is a combination of naturally occuring benzylpenicillin (penicillin G) and the local anaesthetic agent procaine in equimolar amounts. Procaine benzylpenicillin is administered by deep intramuscular injection. It...
Approved
Vet approved
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … It is widely used in veterinary settings. ... (penicillin G) and the local anaesthetic agent procaine in equimolar amounts. ... It is a poorly soluble salt form of penicillin which is a combination of naturally occuring benzylpenicillin …
Matched Categories: … combinations of penicillins …

Pefloxacin

A synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria.
Approved
Matched Iupac: … 1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …

Troglitazone

Troglitazone was withdrawn in 2000 due to risk of hepatotoxicity. It was superseded by pioglitazone and rosiglitazone.
Approved
Investigational
Withdrawn
Matched Description: … Troglitazone was withdrawn in 2000 due to risk of hepatotoxicity. …
Matched Categories: … Drugs Used in Diabetes …

Thiopental

A barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration. It is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure. It does not...
Approved
Vet approved
Matched Description: … It has been used in neurosurgical patients to reduce increased intracranial pressure. ... of complete anesthesia of short duration. ... It is also used for hypnosis and for the control of convulsive states. …
Matched Categories: … combinations of barbiturates …

Levetiracetam

Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders. It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs).[L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918]...
Approved
Matched Description: … It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated ... Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures ... interactions[L8606,L8600,L8615] - these characteristics make it a desirable choice over other AEDs, a class of …
Matched Products: … Levetiracetam in Sodium Chloride …

Tivozanib

Renal cell carcinoma (RCC) is responsible for 3% of cancer cases and is one of the 10 most common cancers in adults. The average age of diagnosis is between age 65 to 74. Tivozanib, also known as FOTIVDA, is a kinase inhibitor developed to treat adult patients with relapsed or...
Approved
Investigational
Matched Description: … cancers in adults. ... Renal cell carcinoma (RCC) is responsible for 3% of cancer cases[A231314] and is one of the 10 most common ... The average age of diagnosis is between age 65 to 74. …

Oxytocin

Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906.[A229008,A228593,A229108] Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues.[A229008,A228593] In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent...
Approved
Vet approved
Matched Description: … [A229108,A229113] It is estimated that labor induction with oxytocin is used in almost 10% of deliveries ... [A229008,A228593,A229108] Like all other neurohypophysial hormones, oxytocin is composed of nine amino ... Dale first identified oxytocin and its uterine contractile properties in 1906. …
Matched Mixtures name: … Bakumokon 7% Minoxidil Sulfate …

Lifitegrast

Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome). It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist that was discovered through the rational design process. The ophthalmic solution was approved in July, 2016 under the trade name Xiidra. It has...
Approved
Matched Description: … onset of action and well tolerated profile in both local and systemic setting [A18805]. ... The ophthalmic solution was approved in July, 2016 under the trade name Xiidra. ... Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome) …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 651 - 675 of 11014 in total