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Displaying drugs 651 - 675 of 4859 in total

Hydralazine

Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed. Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure.[A186820,L8782,L8785] Hydralazine is no longer a...
Approved
Matched Description: … Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and ... hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and ... [T691] Hydralazine hydrochloride was FDA approved on 15 January 1953.[L8779] …
Matched Salts cas: … 304-20-1 …
Matched Mixtures name: … Isosorbide dinitrate and hydralazine hydrochloride ... Isosorbide Dinitrate and Hydralazine Hydrochloride ... Isosorbide Dinitrate and Hydralazine Hydrochloride …
Matched Salts name: … Hydralazine hydrochloride …
Matched Categories: … hydralazine and diuretics ... Hydrazinophthalazine Derivatives and Diuretics …
Matched Products: … Hydralazine Hydrochloride ... HydrALAZINE Hydrochloride ... Apresoline hydrochloride …

Talc

Talc is a mineral composed primarily of magnesium, silicon and oxygen. It is a substance often found in cosmetic and personal hygiene products including baby powder, adult body powders and facial powders. Talc helps absorb moisture, freshen materials, and reduce friction to prevent rashes. Although talc has been widely used...
Approved
Matched Synonyms: … Sterile talc powder ... Talc Powder, Sterile …
Matched Description: … by approximately 30 percent. ... body powders and facial powders. ... Talc is a mineral composed primarily of magnesium, silicon and oxygen. …
Matched Mixtures name: … Foot and Body Powder …
Matched Products: … Sterile Talc ... Steritalc 3g …

Vanillic acid

A flavoring agent. It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin. (J Biotechnol 1996;50(2-3):107-13).
Experimental
Matched Synonyms: … 4-Hydroxy-3-methoxybenzoic acid …
Matched Name: … Vanillic acid …
Matched Iupac: … 4-hydroxy-3-methoxybenzoate …
Matched Description: … It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin. ... (J Biotechnol 1996;50(2-3):107-13). …
Matched Categories: … Hydroxy Acids ... Acids, Carbocyclic ... Carboxylic Acids …

Aspartame

Flavoring agent sweeter than sugar, metabolized as phenylalanine and aspartic acid.
Investigational
Nutraceutical
Matched Synonyms: … 3-Amino-N-(α-methoxycarbonylphenethyl) succinamic acid ... 3-Amino-N-(alpha-methoxycarbonylphenethyl) succinamic acid ... 3-Amino-N-(α-carboxyphenethyl)succinamic acid N-methyl ester …
Matched Iupac: … (3S)-3-amino-3-{[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]carbamoyl}propanoic acid …
Matched Description: … Flavoring agent sweeter than sugar, metabolized as phenylalanine and aspartic acid. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Diet, Food, and Nutrition …
Matched Products: … SIVETA TABLET, 300 ADET ... ASTAT 10 MG TABLET, 300 ADET ... UNOTAT 10 MG TABLET, 300 ADET …

Pyridoxine phosphate

Experimental
Matched Synonyms: … Pyridoxine 5-phosphate …
Matched Name: … Pyridoxine phosphate …
Matched Iupac: … {[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]methoxy}phosphonic acid …
Matched Categories: … Enzymes and Coenzymes …

Magnesium

Magnesium is classified as an alkaline earth metal and has 2 hydration shells. The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate. Common dietary sources of magnesium include nuts (cashews, peanuts, almonds), beans, bananas, apples, carrots, broccoli, and leafy...
Approved
Experimental
Investigational
Matched Description: … and magnesium carbonate. ... [A32810] Further, the mineral helps regulate blood pressure and is necessary for RNA, DNA and protein ... Magnesium is classified as an alkaline earth metal and has 2 hydration shells. …
Matched Mixtures name: … Calcium Folic Acid Plus D Chewable ... Omega-3 Rx Complete ... Folet One …
Matched Products: … Kordel’s Magnesium Amino Acid Chelate 750 Capsules ... BIOLECTRA MAGN 365 FOR ORA ... BIOLECTRA MAGN 365 FOR ZIT …

Ephedrine

Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with pseudoephedrine. Ephedrine acts as both a direct and indirect sympathomimetic. It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons,...
Approved
Matched Description: … [A193698] Ephedrine acts as both a direct and indirect sympathomimetic. ... It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of ... norepinephrine from sympathetic neurons, inhibiting norepinephrine reuptake and displacing more norepinephrine …
Matched Salts cas: … 1405-94-3 …
Matched Salts name: … Ephedrine hydrochloride …
Matched Categories: … Adrenergic and Dopaminergic Agents ... Alimentary Tract and Metabolism ... Alpha-and Beta-adrenergic Agonists ... Epinephrine and similars ... Herbs and Natural Products …
Matched Products: … Edeline Injection 30 mg/ml ... RINITALMIT LIQUIDE, 30 ML ... EPHEDRINE HYDROCHLORIDE …

3-Amino-3-Oxopropanoic Acid

Experimental
Matched Name: … 3-Amino-3-Oxopropanoic Acid …
Matched Iupac: … 2-carbamoylacetic acid …

3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid

Experimental
Matched Synonyms: … 3-deoxy-α-D-manno-oct-2-ulopyranosonic acid ... α-2-keto-3-deoxyoctulosonic acid pyranose …
Matched Name: … 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid …
Matched Iupac: … (2R,4R,5R,6R)-6-[(1R)-1,2-dihydroxyethyl]-2,4,5-trihydroxyoxane-2-carboxylic acid …

Nitroarginine

An inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity. Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in brain energy and ammonia metabolites. (Neurochem Res 1995:200(4):451-6)
Experimental
Investigational
Matched Synonyms: … omega-Nitroarginine …
Matched Iupac: … (2S)-2-amino-5-(N'-nitrocarbamimidamido)pentanoic acid …
Matched Description: … alterations in brain energy and ammonia metabolites. ... Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …

Bromfenac

Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were...
Approved
Withdrawn
Matched Synonyms: … 2-amino-3-(4-bromobenzoyl)benzeneacetic acid ... [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid …
Matched Iupac: … 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid …
Matched Description: … Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. ... Their well-characterized anti-inflammatory activity, analgesic property, and established safety record …
Matched Salts cas: … 120638-55-3 …

DL-Methylephedrine

Methylephedrine is a sympathomimetic amine that appears in various over-the-counter cough and cold medications throughout the world , , . The abuse of methylephedrine-containing medications has been reported in Japan. Methylephedrine is not legally available in the United States, but has been identified in cases of drug abuse .
Approved
Matched International brands: … dl-Methylephedrine Hydrochloride 10% Metal ... dl-Methylephedrine Hydrochloride 10% Maruishi ... dl-Methylephedrine Hydrochloride 10% Sanwa …
Matched Description: … Methylephedrine is a sympathomimetic amine that appears in various over-the-counter cough and cold medications …
Matched Salts name: … DL-Methylephedrine hydrochloride …

Alprostadil

Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men for whom oral treatment...
Approved
Investigational
Matched Synonyms: … 11α,15α-dihydroxy-9-oxo-13-trans-prostenoic acid ... (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid …
Matched Iupac: … 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid …
Matched Description: … intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and ... This drug causes vasodilation by directly affecting vascular and ductus arteriosus (DA) smooth muscle …
Matched Mixtures name: … Caverject Sterile Powder - Kit 11.9mcg /vial …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated ... Genito Urinary System and Sex Hormones …
Matched Products: … Vitaros 3 mg/g - Creme ... VİRİREC 3 MG/G KREM, 4 ADET ... PROSTAVASIN 20 MCG I.A/I.V INFÜZYON IÇIN KURU TOZ IÇEREN AMPUL, 30 AMPUL …

Gamolenic acid

Gamolenic acid, or gamma-linolenic acid (γ-Linolenic acid) or GLA, is an essential fatty acid (EFA) comprised of 18 carbon atoms with three double bonds that is most commonly found in human milk and other botanical sources . It is an omega-6 polyunsaturated fatty acid (PUFA) also referred to as 18:3n-6;...
Approved
Investigational
Matched Synonyms: … 18:3 (n-6) ... gamoleic acid ... Gamolenic acid …
Matched Name: … Gamolenic acid …
Matched Iupac: … (6Z,9Z,12Z)-octadeca-6,9,12-trienoic acid …
Matched Description: … It is an omega-6 polyunsaturated fatty acid (PUFA) also referred to as 18:3n-6; 6,9,12-octadecatrienoic ... acid; and cis-6, cis-9, cis-12- octadecatrienoic acid [F27]. ... ] and [DB11238] are rich sources of gamolenic acid. …
Matched Categories: … Fatty Acids, Omega-6 ... Fatty Acids ... Fatty Acids, Essential ... Fatty Acids, Unsaturated ... gamolenic acid …

Lonidamine

Lonidamine (LND) is a drug that interferes with energy metabolism of cancer cells, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK). In such way LND could impair energy-requiring processes, as recovery from potentially lethal damage, induced by radiation treatment and by some cytotoxic drugs.
Investigational
Matched Synonyms: … 1-(2,4-dichlorbenzyl)-indazole-3-carboxylic acid ... diclondazolic acid …
Matched Iupac: … 1-[(2,4-dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid …
Matched Description: … energy-requiring processes, as recovery from potentially lethal damage, induced by radiation treatment and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Acetylcysteine

Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Synonyms: … (2R)-2-acetylamino-3-sulfanylpropanoic acid ... (R)-2-acetylamino-3-mercaptopropanoic acid ... Mercapturic acid …
Matched Iupac: … (2R)-2-acetamido-3-sulfanylpropanoic acid …
Matched Description: … Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal ... ASIST C 600 MG-300 MG TOZ IÇEREN SAŞE,30 SAŞE …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur ... Cough and Cold Preparations …
Matched Products: … XPECTO 300 MG SAŞE, 30 ADET ... N-ACETILCISTEINA 300 MG/3 ML ... SISTECS 300 MG/3 ML ÇÖZELTI, 10 ADET …

Imipramine

Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts...
Approved
Matched Synonyms: … 5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine …
Matched Iupac: … (3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}propyl)dimethylamine …
Matched Description: … and clomipramine. ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... than secondary amine TCAs, such as nortriptyline and desipramine. …
Matched Salts name: … Imipramine hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Heterocyclic Compounds, 3-Ring …
Matched Products: … SILEDX-3 ... Imipramine Hydrochloride ... Imipramine hydrochloride …

Oxothiazolidinecarboxylic acid

Procysteine has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Synonyms: … (-)-2-OXO-4-THIAZOLIDINECARBOXYLIC ACID ... (R)-2-OXOTHIAZOLIDINE-4-CARBOXYLIC ACID ... L-2-OXO-4-THIAZOLIDINECARBOXYLIC ACI …
Matched Name: … Oxothiazolidinecarboxylic acid …
Matched Iupac: … (4R)-2-oxo-1,3-thiazolidine-4-carboxylic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic …

(S)-DES-ME-AMPA

Experimental
Matched Synonyms: … (S)-2-amino-3-(3-hydroxy-isoxazol-4-yl)propionic acid …
Matched Iupac: … (2S)-2-amino-3-(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)propanoic acid …

Ataluren

Ataluren is a novel, orally administered drug that targets nonsense mutations. Ataluren is approved for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and older who are able to walk. More specifically, ataluren is used in the small group of patients whose...
Approved
Investigational
Matched Synonyms: … 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid …
Matched Iupac: … 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid …
Matched Description: … use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and ... This drug does not yet have approval by the US Food and Drug Administration or by Health Canada for any …

Adenylyl-(3'-5')-uridine 3'-monophosphate

Experimental
Matched Synonyms: … Adenylyl-(3'-5')-3'-uridylic acid ... Adenylyl-3'-5'-phospho-uridine-3'-monophosphate …
Matched Name: … Adenylyl-(3'-5')-uridine 3'-monophosphate …
Matched Iupac: … yl]oxy}phosphonic acid ... {[(2R,3S,4R,5R)-2-{[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl ... ]oxy}(hydroxy)phosphoryl)oxy]methyl}-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-hydroxyoxolan-3- …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

3-(CARBOXYMETHOXY)THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID

Experimental
Matched Name: … 3-(CARBOXYMETHOXY)THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID …
Matched Iupac: … 3-(carboxymethoxy)thieno[2,3-b]pyridine-2-carboxylic acid …

Mecapegfilgrastim

Mecapegfilgrastim is under investigation in clinical trial NCT05463601 (Mecapegfilgrastim for the Prevention of Dalpiciclib -Induced Neutropenia in Advanced Breast Cancer).
Investigational
Matched Synonyms: … -.omega. ... .-(((2-((3-(3-((3-aminopropyl)thio)-2,5-dioxo-1-pyrrolidinyl)-1-oxopropyl)amino)ethyl)amino)carbonyl) …

3-deoxy-D-arabino-hexonic acid

Experimental
Matched Synonyms: … 3-Deoxy-arabino-hexonic acid ... D-2-keto-3-deoxygluconate …
Matched Name: … 3-deoxy-D-arabino-hexonic acid …
Matched Iupac: … (2S,4S,5R)-2,4,5,6-tetrahydroxyhexanoic acid …
Matched Categories: … Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids …

Alclofenac

Alclofenac is a non-steroidal anti-inflammatory drug. It was withdrawn from the market in the United Kingdom in 1979.
Approved
Withdrawn
Matched Synonyms: … [4-(allyloxy)-3-chlorophenyl]acetic acid ... 3-Chloro-4-(2-propenyloxy)benzeneacetic acid ... (4-Allyloxy-3-chlorphenyl)essigsäure …
Matched Iupac: … 2-[3-chloro-4-(prop-2-en-1-yloxy)phenyl]acetic acid …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Acids, Carbocyclic ... Carboxylic Acids ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Displaying drugs 651 - 675 of 4859 in total