Displaying drugs 676 - 700 of 1634 in total
Basiliximab
A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known as CD25 antigen) on the surface of activated T-lymphocytes. It is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cell...
Approved
Investigational
Matched Description: … light chain constant region genes and mouse heavy and light chain variable region genes encoding the ... ) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and ... established mouse myeloma cell line genetically engineered to express plasmids containing the human heavy and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … SIMULECT LYOPHILISATE FOR INJECTION 20MG PER VIAL …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … SIMULECT LYOPHILISATE FOR INJECTION 20MG PER VIAL …
Eravacycline
Eravacycline, known as Xerava by Tetraphase Pharmaceuticals, is a fully synthetic fluorocycline antibiotic of the tetracycline class with activity against clinically significant gram-negative, gram-positive aerobic, and facultative bacteria. This includes most of those bacteria resistant to cephalosporins, fluoroquinolones, β-lactam/β-lactamase inhibitors, multidrug-resistant strains, and carbapenem-resistant Enterobacteriaceae, and the majority of anaerobic...
Approved
Investigational
Matched Description: … tetracycline class with activity against clinically significant gram-negative, gram-positive aerobic, and ... carbapenem-resistant Enterobacteriaceae, and the majority of anaerobic pathogens [A38683]. ... to cephalosporins, fluoroquinolones, β-lactam/β-lactamase inhibitors, multidrug-resistant strains, and …
Matched Products: … XERAVA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 50MG PER VIAL …
Matched Products: … XERAVA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 50MG PER VIAL …
Tedizolid phosphate
Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Matched Synonyms: … [(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl …
Matched Iupac: … {[(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-1,2,3,4-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin- …
Matched Description: … ) and is generally more effective and more tolerable than [linezolid]. ... [A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the ... such as methicillin-resistant _Staphylococcus aureus_, vancomycin-resistant _Enterococcus faecium_, and …
Matched Products: … SIVEXTRO LYOPHILIZED POWDER FOR SOLUTION FOR INFUSION 200MG PER VIAL …
Matched Iupac: … {[(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-1,2,3,4-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin- …
Matched Description: … ) and is generally more effective and more tolerable than [linezolid]. ... [A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the ... such as methicillin-resistant _Staphylococcus aureus_, vancomycin-resistant _Enterococcus faecium_, and …
Matched Products: … SIVEXTRO LYOPHILIZED POWDER FOR SOLUTION FOR INFUSION 200MG PER VIAL …
Elafibranor
Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist. On June 10, 2024, elafibranor was granted accelerated approval by the FDA for the treatment of primary biliary cholangitis (PBC).
Approved
Investigational
Matched Synonyms: … PROPANOIC ACID, 2-(2,6-DIMETHYL-4-((1E)-3-(4-(METHYLTHIO)PHENYL)-3-OXO-1-PROPEN-1-YL)PHENOXY)- ... PROPANOIC ACID, 2-(2,6-DIMETHYL-4-(3-(4-(METHYLTHIO)PHENYL)-3-OXO-1-PROPEN-1-YL)PHENOXY)-2-METHYL- …
Matched Iupac: … 2-{2,6-dimethyl-4-[(1E)-3-[4-(methylsulfanyl)phenyl]-3-oxoprop-1-en-1-yl]phenoxy}-2-methylpropanoic acid …
Matched Description: … Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist. …
Matched Categories: … Alimentary Tract and Metabolism ... Bile and Liver Therapy …
Matched Iupac: … 2-{2,6-dimethyl-4-[(1E)-3-[4-(methylsulfanyl)phenyl]-3-oxoprop-1-en-1-yl]phenoxy}-2-methylpropanoic acid …
Matched Description: … Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist. …
Matched Categories: … Alimentary Tract and Metabolism ... Bile and Liver Therapy …
Cilastatin
Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. Since the antibiotic, imipenem, is one such antibiotic that is hydrolyzed by dehydropeptidase, cilastatin is used in combination with imipenem to prevent...
Approved
Investigational
Matched Description: … [L7628] A newer triple-drug product was approved in July 2019 under the trade name Recarbrio which also …
Matched Mixtures name: … Imipenem and Cilastatin ... Imipenem and Cilastatin ... Imipenem and Cilastatin …
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …
Matched Products: … IMCIL POWDER FOR SOLUTION FOR INJECTION OR INFUSION 500MG/500MG PER VIAL …
Matched Mixtures name: … Imipenem and Cilastatin ... Imipenem and Cilastatin ... Imipenem and Cilastatin …
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …
Matched Products: … IMCIL POWDER FOR SOLUTION FOR INJECTION OR INFUSION 500MG/500MG PER VIAL …
Tedizolid
Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Investigational
Matched Iupac: … (5R)-3-{3-fluoro-4-[6-(2-methyl-2H-1,2,3,4-tetrazol-5-yl)pyridin-3-yl]phenyl}-5-(hydroxymethyl)-1,3-oxazolidin …
Matched Description: … ) and is generally more effective and more tolerable than [linezolid]. ... [A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the ... such as methicillin-resistant _Staphylococcus aureus_, vancomycin-resistant _Enterococcus faecium_, and …
Matched Products: … SIVEXTRO LYOPHILIZED POWDER FOR SOLUTION FOR INFUSION 200MG PER VIAL …
Matched Description: … ) and is generally more effective and more tolerable than [linezolid]. ... [A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the ... such as methicillin-resistant _Staphylococcus aureus_, vancomycin-resistant _Enterococcus faecium_, and …
Matched Products: … SIVEXTRO LYOPHILIZED POWDER FOR SOLUTION FOR INFUSION 200MG PER VIAL …
Methylnaltrexone
Methylnaltrexone is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation without producing analgesic effects or withdrawal symptoms. It is also a weak CYP2D6 inhibitor. FDA approved in 2008.
Approved
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … RELISTOR (TM) (SUBCUTANEOUS INJECTION,12MG/0.6ML PER VIAL) …
Matched Products: … RELISTOR (TM) (SUBCUTANEOUS INJECTION,12MG/0.6ML PER VIAL) …
DPM-1001
Investigational
Matched Synonyms: … Methyl (3β,5α,7α)-7-hydroxy-3-[[4-[(2-pyridinylmethyl)amino]butyl]amino]cholan-24-oate ... Cholan-24-oic acid, 7-hydroxy-3-[[4-[(2-pyridinylmethyl)amino]butyl]amino]-, methyl ester, (3β,5α,7α) …
Permethrin
A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.
Approved
Investigational
Matched Description: … A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides and Pediculicides ... Scabicides, Insecticides and Repellents ... Phenols ... Phenyl Ethers …
Matched Products: … BALSAMO ANTIPIOJOS CRUZ AZUL …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides and Pediculicides ... Scabicides, Insecticides and Repellents ... Phenols ... Phenyl Ethers …
Matched Products: … BALSAMO ANTIPIOJOS CRUZ AZUL …
Fosbretabulin
Fosbretabulin has been investigated for the treatment of Anaplastic Thyroid Cancer.
Investigational
Matched Synonyms: … 2-METHOXY-5-((Z)-2-(3,4,5-TRIMETHOXYPHENYL)VINYL)PHENYL DIHYDROGEN PHOSPHATE ... PHENOL, 2-METHOXY-5-((Z)-2-(3,4,5-TRIMETHOXYPHENYL)ETHENYL)-, DIHYDROGEN PHOSPHATE ... PHENOL, 2-METHOXY-5-((1Z)-2-(3,4,5-TRIMETHOXYPHENYL)ETHENYL)-,1-(DIHYDROGEN PHOSPHATE) …
Matched Iupac: … {2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy}phosphonic acid …
Matched Iupac: … {2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy}phosphonic acid …
Monobenzone
Monobenzone is the monobenzyl ether of hydroquinone used medically for depigmentation. Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water. It exerts a depigmenting effect on skin of mammals by increasing the excretion of melanin from the melanocytes. It may also cause...
Approved
Matched Synonyms: … 4-(Benzyloxy)phenol ... 4-Benzyloxy-phenol ... 4-(Benzyloxyl)phenol …
Matched Iupac: … 4-(benzyloxy)phenol …
Matched Description: … Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically ... It may also cause destruction of melanocytes and permanent depigmentation. …
Matched Categories: … Phenols …
Matched Iupac: … 4-(benzyloxy)phenol …
Matched Description: … Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically ... It may also cause destruction of melanocytes and permanent depigmentation. …
Matched Categories: … Phenols …
Sulpiride
Sulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. Sulpiride is not approved by the FDA, Health Canada, or the EMA; though...
Approved
Investigational
Matched Categories: … Benzamides and benzamide derivatives …
Matched Products: … DOGMATIL 200 MG TABLET, 24 ADET ... MERESA FORT 200 MGTABLET, 24 ADET …
Matched Products: … DOGMATIL 200 MG TABLET, 24 ADET ... MERESA FORT 200 MGTABLET, 24 ADET …
Phenyl hydrogen sulfate
Experimental
Matched Synonyms: … Phenol sulfate …
Matched Name: … Phenyl hydrogen sulfate …
Matched Name: … Phenyl hydrogen sulfate …
Betula pendula pollen
Betula pendula pollen allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … European white birch pollen …
NAP-226-90
Experimental
Matched Synonyms: … 3-((1S)-1-(Dimethylamino)ethyl)phenol ... (-)-3-((1S)-1-(Dimethylamino)ethyl)phenol …
Matched Iupac: … 3-[(1S)-1-(dimethylamino)ethyl]phenol …
Matched Iupac: … 3-[(1S)-1-(dimethylamino)ethyl]phenol …
Bocidelpar
Investigational
Matched Synonyms: … Hexanoic acid, 3-methyl-6-(2-((5-methyl-2-(4-(trifluoromethyl)phenyl)-1h-imidazol-1-yl)methyl)phenoxy …
Matched Iupac: … (3R)-3-methyl-6-[2-({5-methyl-2-[4-(trifluoromethyl)phenyl]-1H-imidazol-1-yl}methyl)phenoxy]hexanoic …
Matched Iupac: … (3R)-3-methyl-6-[2-({5-methyl-2-[4-(trifluoromethyl)phenyl]-1H-imidazol-1-yl}methyl)phenoxy]hexanoic …
Silicon dioxide
Silicon dioxide, or silica, is an oxide of silicon with the chemical formula SiO2. It is found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite as transparent and tasteless crystals. Inhalation of fine crystals is toxic to humans leading to respiratory toxicity. In powdered food products...
Approved
Matched Description: … as transparent and tasteless crystals. ... It is found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite ... Colloidal silica is also used as a wine, beer, and juice fining agent or stabilizer. …
Matched Mixtures name: … Calcium and Magnesium 1:1 Plus Tablets ... Men's Biomultiple Vitamin and Mineral Supplement ... Women's Biomultiple Vitamin and Mineral Supplement …
Matched Products: … Oprecare 24 …
Matched Mixtures name: … Calcium and Magnesium 1:1 Plus Tablets ... Men's Biomultiple Vitamin and Mineral Supplement ... Women's Biomultiple Vitamin and Mineral Supplement …
Matched Products: … Oprecare 24 …
ONO-7579
Investigational
Matched Synonyms: … phenyl]urea ... 1-[2-[4-(2-amino-5-chloropyridin-3-yl)phenoxy]pyrimidin-5-yl]-3-[2-methylsulfonyl-5-(trifluoromethyl) …
Alprostadil
Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men for whom oral treatment...
Approved
Investigational
Matched Description: … intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and ... This drug causes vasodilation by directly affecting vascular and ductus arteriosus (DA) smooth muscle …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … Alprostadil "Pint" 20 Mikrogramm - Konzentrat zur Infusionsbereitung ... Alprostadil „PINT“ 500 Mikrogramm - Konzentrat zur Herstellung einer Infusionslösung …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … Alprostadil "Pint" 20 Mikrogramm - Konzentrat zur Infusionsbereitung ... Alprostadil „PINT“ 500 Mikrogramm - Konzentrat zur Herstellung einer Infusionslösung …
TW-37
TW-37 is a small-molecule inhibitor of Bcl-2 investigated for its anti-cancer properties.
Investigational
Matched Synonyms: … phenyl)methyl)- ... N-(4-((2-(1,1-dimethylethyl)phenyl)sulfonyl)phenyl)-2,3,4-trihydroxy-5-((2-(1-methylethyl)phenyl)methyl ... N-[4-[[2-(1,1-Dimethylethyl)phenyl]sulfonyl]phenyl]-2,3,4-trihydroxy-5-[[2-(1-methylethyl)phenyl]methyl …
Matched Iupac: … N-[4-(2-tert-butylbenzenesulfonyl)phenyl]-2,3,4-trihydroxy-5-{[2-(propan-2-yl)phenyl]methyl}benzamide …
Matched Iupac: … N-[4-(2-tert-butylbenzenesulfonyl)phenyl]-2,3,4-trihydroxy-5-{[2-(propan-2-yl)phenyl]methyl}benzamide …
Hydrotalcite
Approved
Experimental
Investigational
Matched Categories: … Alimentary Tract and Metabolism ... Aluminum and magnesium containing antacids …
Matched Products: … HIDRASIT 1000 MG ÇİĞNEME TABLET, 24 ADET …
Matched Products: … HIDRASIT 1000 MG ÇİĞNEME TABLET, 24 ADET …
Oxybutynin
Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients worldwide. Due to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social embarrassment and a poor quality of life.[A185996,A185999]
Oxybutynin, also marketed as Ditropan XL, is an anticholinergic medication used for...
Approved
Investigational
Matched Description: … embarrassment and a poor quality of life. ... Due to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social ... used for the relief of overactive bladder symptoms that has been optimized for high levels of safety and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … KENTERA 3,9 MG/24 SAAT TRANSDERMAL FLASTER …
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … KENTERA 3,9 MG/24 SAAT TRANSDERMAL FLASTER …
Phenyl aminosalicylate
Approved
Matched Synonyms: … Phenyl PAS ... Phenyl aminosalicylate ... Phenyl 4-aminosalicylate …
Matched Name: … Phenyl aminosalicylate …
Matched Iupac: … phenyl 4-amino-2-hydroxybenzoate …
Matched Categories: … Phenols …
Matched Name: … Phenyl aminosalicylate …
Matched Iupac: … phenyl 4-amino-2-hydroxybenzoate …
Matched Categories: … Phenols …
Methylene blue
Methylene blue is an oxidation-reduction agent. The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult patients with acquired methemoglobinemia. Historically, it has been widely used in Africa to treat malaria, but now it disappeared when chloroquine (CQ) and other drugs entered...
Approved
Investigational
Matched Synonyms: … Solvent blue 8 …
Matched Description: … The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult ... Historically, it has been widely used in Africa to treat malaria, but now it disappeared when chloroquine (CQ) and ... proposed trade name Rember) is an investigational drug being developed by the University of Aberdeen and …
Matched Description: … The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult ... Historically, it has been widely used in Africa to treat malaria, but now it disappeared when chloroquine (CQ) and ... proposed trade name Rember) is an investigational drug being developed by the University of Aberdeen and …
Hydroxychloroquine
Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. Hydroxychloroquine is an aminoquinoline like chloroquine. It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus. Hydroxychloroquine is also used for the prophylaxis of malaria in...
Approved
Matched Description: … Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. ... the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and ... [A183092] Chloroquine and hydroxychloroquine are both being investigated for the treatment of SARS-CoV …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Products: … PLAQUENIL TABLET 200 mg (White) …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Products: … PLAQUENIL TABLET 200 mg (White) …
Displaying drugs 676 - 700 of 1634 in total