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Displaying drugs 676 - 700 of 789 in total

RGX-121

RGX-121 is designed to use the NAV AAV9 vector to deliver the human iduronate-2-sulfatase gene to the central nervous system.
Investigational
Matched Synonyms: … Non-replicating recombinant adeno-associated virus (AAV) vector of serotype 9 expressing human iduronate-2-sulfatase …
Matched Description: … RGX-121 is designed to use the NAV AAV9 vector to deliver the human iduronate-2-sulfatase gene to the …

Duloxetine

Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder. It has since received approval for a...
Approved
Matched Description: … [label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. ... Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor. ... Duloxetine continues to be investigated for the treatment of pain in cancer, surgery, and more. …
Matched Salts name: … Duloxetine hydrochloride …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors …
Matched Products: … Duloxetine hydrochloride ... Duloxetine Hydrochloride ... Duloxetine Hydrochloride 20 mg …

Betaxolol

A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
Approved
Investigational
Matched Salts name: … Betaxolol hydrochloride …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Betaxolol Hydrochloride …

Acebutolol

A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.
Approved
Investigational
Matched Description: … The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic …
Matched Salts name: … Acebutolol hydrochloride …
Matched Categories: … acebutolol and thiazides ... Beta Blocking Agents and Thiazides ... Beta Blocking Agents, Selective, and Thiazides …
Matched Products: … Acebutolol Hydrochloride …

Meropenem

Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death. In August 2017, a combination antibacterial therapy under the market name vabomere...
Approved
Investigational
Matched Description: … Vabomere consists of meropenem and [DB12107] and is intravenously admininstered. ... It is active against Gram-positive and Gram-negative bacteria. ... Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis …
Matched Categories: … meropenem and vaborbactam …
Matched Products: … Meropenem and Sodium Chloride ... Meropenem for Injection USP and Sodium Chloride Injection USP …

CypCaps

Investigational
Matched Synonyms: … P450 isoform 2B1 gene transfected human embryonic kidney 293 cells encapsulated in polymeric cellulose sulphate …

Sertraline

Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before...
Approved
Matched Description: … is similar to drugs such as [Citalopram] and [Fluoxetine]. ... popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and ... classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and …
Matched Salts name: … Sertraline hydrochloride …
Matched Products: … Sertraline Hydrochloride ... Sertraline hydrochloride ... SERTRAline Hydrochloride …

Flavoxate

A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]
Approved
Matched Description: … Its therapeutic usefulness and its mechanism of action are not clear. ... A drug that has been used in various urinary syndromes and as an antispasmodic. ... It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity …
Matched Salts name: … Flavoxate hydrochloride …
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … Flavoxate Hydrochloride …

Lincomycin

Lincomycin is a lincosamide antibiotic first isolated from the soil bacterium Streptomyces lincolnensis in Lincoln, Nebraska. Clinical use of lincomycin has largely been superseded by its semisynthetic derivative clindamycin due to its higher efficacy and a wider range of susceptible organisms, though lincomycin remains in use.[A190657, A190621] Lincomycin was approved...
Approved
Vet approved
Matched Description: … has largely been superseded by its semisynthetic derivative [clindamycin] due to its higher efficacy and …
Matched Salts name: … Lincomycin hydrochloride ... Lincomycin hydrochloride monohydrate …
Matched Categories: … Macrolides, Lincosamides and Streptogramins …
Matched Products: … Lincomycin Hydrochloride ... Lincomycin hydrochloride …

Heparin

Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Description: … coagulation enzymes thrombin (factor IIa) and factor Xa. ... UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. ... Furthermore, the effects of UH can typically be reversed by using protamine sulfate. …
Matched Mixtures name: … Heparin Sodium and Dextrose 5% Inj USP ... Heparin Sod and 0.9% Sod Chloride Inj …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs …
Matched Products: … Heparin Sodium and Dextrose ... Heparin Sodium and Sodium Chloride …

Pyridoxine

Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. While many plants and microorganisms are...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … and pyridoxamine 5'-phosphate. ... glycogen, the synthesis of nucleic acids, hemogloblin, sphingomyelin and other sphingolipids, and the ... As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required …
Matched Mixtures name: … Doxylamine succinate and pyridoxine hydrochloride ... Doxylamine succinate and pyridoxine hydrochloride ... Doxylamine Succinate and Pyridoxine Hydrochloride …
Matched Salts name: … Pyridoxine hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... isoniazid, sulfamethoxazole, trimethoprim and pyridoxine …
Matched Products: … Pyridoxine Hydrochloride ... Pyridoxine Hydrochloride Injection, USP ... Pyridoxine Hydrochloride Injection 100mg/ml …

Thioridazine

A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed,...
Approved
Withdrawn
Matched Description: … A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the …
Matched Salts name: … Thioridazine hydrochloride …
Matched Products: … Thioridazine Hydrochloride …

Hydrocortisone acetate

Approved
Vet approved
Matched Mixtures name: … Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate …
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … American Safety and First Aid …

Nortriptyline

Nortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Approved
Matched Description: … and other conditions. ... [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain ... Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant …
Matched Salts name: … Nortriptyline hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Nortriptyline Hydrochloride …

Granisetron

A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Approved
Investigational
Matched Description: … A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant …
Matched Salts name: … Granisetron hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants …
Matched Products: … Granisetron Hydrochloride ... Granisetron hydrochloride ... GRANISETRON HYDROCHLORIDE …

Clindamycin

Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris. It has a relatively narrow spectrum of activity that includes anaerobic bacteria as well as gram-positive cocci and bacilli and gram-negative bacilli. Interestingly,...
Approved
Vet approved
Matched Description: … bacilli and gram-negative bacilli. ... used off-label in the treatment of toxoplasmosis, malaria, and babesiosis. ... [A190621] Interestingly, clindamycin appears to carry some activity against protozoans, and has been …
Matched Mixtures name: … Clindamycin and Benzoyl Peroxide ... Clindamycin Phosphate and Tretinion ... Clindamycin and Benzoyl Peroxide …
Matched Salts name: … Clindamycin hydrochloride ... Clindamycin palmitate hydrochloride …
Matched Categories: … Genito Urinary System and Sex Hormones ... Macrolides, Lincosamides and Streptogramins ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Clindamycin Hydrochloride ... Clindamycin hydrochloride ... Cleocin Hydrochloride …

Maprotiline

Maprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs). Similar to TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and does not affect monoamine oxidase activity. It differs from TCAs in that it does not appear to block serotonin reuptake. Maprotiline may be used...
Approved
Investigational
Matched Description: … TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and ... be used to treat depressive affective disorders, including dysthymic disorder (depressive neurosis) and …
Matched Salts name: … Maprotiline hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Maprotiline Hydrochloride …

Stavudine

A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Approved
Investigational
Matched Synonyms: … 1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine …
Matched Description: … A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV. …
Matched Categories: … stavudine and lamivudine ... stavudine, lamivudine and nevirapine ... Nucleic Acids, Nucleotides, and Nucleosides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …

Levonorgestrel

Levonorgestrel (LNG) is a synthetic progestogen similar to Progesterone used in contraception and hormone therapy.[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. Some of these devices...
Approved
Investigational
Matched Description: … Some of these devices are known as Jaydess, Kyleena, and Mirena. ... Levonorgestrel (LNG) is a synthetic progestogen similar to [Progesterone] used in contraception and hormone ... [A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as …
Matched Mixtures name: … Levonorgestrel and Ethinyl Estradiol and Ethinyl Estradiol ... Levonorgestrel and Ethinyl Estradiol and Ethinyl Estradiol ... Levonorgestrel and Ethinyl Estradiol and Ethinyl Estradiol …
Matched Categories: … levonorgestrel and estrogen ... levonorgestrel and estrogen ... Genito Urinary System and Sex Hormones ... levonorgestrel and ethinylestradiol ... levonorgestrel and ethinylestradiol …
Matched Products: … ONE-AND-ONE …

Sevelamer

Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Salts name: … Sevelamer hydrochloride …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Products: … Sevelamer Hydrochloride ... Sevelamer hydrochloride …

Mitoxantrone

An anthracenedione-derived antineoplastic agent.
Approved
Investigational
Matched Salts name: … Mitoxantrone hydrochloride …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Mitoxantrone Hydrochloride …

Remifentanil

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Approved
Matched Description: … causes respiratory depression and analgesia. ... Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and ... a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and …
Matched Salts name: … Remifentanil hydrochloride …
Matched Categories: … Hypnotics and Sedatives ... Fentanyl and fentanyl analogues …
Matched Products: … Remifentanil Hydrochloride ... Remifentanil Hydrochloride for Injection …

Paroxetine

Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline...
Approved
Investigational
Matched Description: … of serotonin reuptake and has little effect on other neurotransmitters. ... [T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. ... uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and …
Matched Salts name: … Paroxetine hydrochloride ... Paroxetine hydrochloride hemihydrate …
Matched Products: … Paroxetine Hydrochloride ... Paroxetine Hydrochloride CR ... Paroxetine Hydrochloride Anhydrous …

Darunavir

Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as ritonavir for the effective management of HIV-1 infection. As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006. Darunavir is being...
Approved
Matched Description: … [A191682] Clinical trials are underway and are expected to conclude in August 2020.[L12066] …
Matched Categories: … darunavir and ritonavir ... darunavir and cobicistat ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... emtricitabine, tenofovir alafenamide, darunavir and cobicistat …
Matched Products: … Darunavir 600 and 800 mg …

Tramadol

Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine. Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain. It is considered...
Approved
Investigational
Matched Description: … of and response to pain. ... such as [duloxetine] and [venlafaxine]. ... ) that is structurally related to [codeine] and [morphine]. …
Matched Mixtures name: … Tramadol Hydrochloride and Acetaminophen ... Tramadol Hydrochloride and Acetaminophen ... Tramadol Hydrochloride and Acetaminophen …
Matched Salts name: … Tramadol hydrochloride …
Matched Categories: … tramadol and celecoxib ... tramadol and paracetamol ... tramadol and dexketoprofen …
Matched Products: … Tramadol Hydrochloride ... Tramadol Hydrchloride ... Tramadol hydrochloride …
Displaying drugs 676 - 700 of 789 in total