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Displaying drugs 51 - 75 of 11798 in total
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Approved
Matched Synonyms: … 4-[p-[bis(2-chloroethyl)amino]phenyl]butyric acid ... γ-[p-di(2-chloroethyl)aminophenyl]butyric acid ... N,N-di-2-chloroethyl-γ-p-aminophenylbutyric acid …
Matched Iupac: … 4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid …
Matched Products: … ลูเคอแรน (เม็ด 2 มก.) ... Leukeran 2 mg - Filmtabletten ... LEUKERAN 2 MG TABLET, 25 ADET …
A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
Approved
Vet approved
Matched Synonyms: … 2-Benzyl-2-imidazoline ... 2-Benzylimidazoline ... 2-Benzyl-4,5-imidazoline …
Matched Iupac: … 2-benzyl-4,5-dihydro-1H-imidazole …
Matched Salts cas: … 59-97-2
Approved
Experimental
Matched Synonyms: … 2-Phenyl-4-chromone ... 2-phenylchromone ... 2-Phenyl-4-benzopyron …
Matched Iupac: … 2-phenyl-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Mebutamate is a sedative and anxiolytic drug with anti-hypertensive (blood pressure lowering) effects comparable to those of other barbiturates but is only around 1/3rd the potency of secobarbital as a sedative. Side effects include dizziness and headaches.
Approved
Matched Synonyms: … 2-Methyl-2-sec-butyl-1,3-propanediol dicarbamate ... 2-sec-Butyl-2-methyl-1,3-propanediol dicarbamate ... 2-sec-Butyl-2-methyltrimethylene dicarbamate …
Matched Iupac: … 2-[(carbamoyloxy)methyl]-2,3-dimethylpentyl carbamate …
Bromocriptine mesylate is a semisynthetic ergot alkaloid derivative with potent dopaminergic activity. It inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia. Bromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Syndrome, as well as the treatment of acromegaly. Bromocriptine has been...
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-bromo-α-ergokryptin ... 2-bromo-α-ergocryptine ... 2-Bromo-alpha-ergocryptine …
Matched Iupac: … (4R,7R)-10-bromo-N-[(1S,2S,4R,7S)-2-hydroxy-7-(2-methylpropyl)-5,8-dioxo-4-(propan-2-yl)-3-oxa-6,9-diazatricyclo …
Matched Categories: … Adrenergic alpha-2 Receptor Agonists …
A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Synonyms: … 1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine ... 2-cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine ... N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine …
Matched Iupac: … (Z)-N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine …
Matched Salts cas: … 70059-30-2
Matched Mixtures name: … Cimetidine 5% / Ibuprofen 2% / Salicylic Acid 17% …
Matched Categories: … MATE 2 Inhibitors ... MATE 2 Substrates …
Matched Products: … ไซแอมมิดีน ชนิดฉีด (100 มก./มล.) …
Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections. It is most commonly used to treat herpes zoster (shingles). Famciclovir is a prodrug of penciclovir with higher oral bioavailability.
Approved
Investigational
Matched Synonyms: … 2-(2-(2-amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate ... acetic acid 2-acetoxymethyl-4-(2-amino-purin-9-yl)-butyl ester ... 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine …
Matched Iupac: … 2-[(acetyloxy)methyl]-4-(2-amino-9H-purin-9-yl)butyl acetate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. While many plants and microorganisms are...
Approved
Investigational
Nutraceutical
Vet approved
Matched Synonyms: … 2-methyl-3-hydroxy-4,5-dihydroxymethylpyridine ... 3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine …
Matched Iupac: … 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol …
Matched Mixtures name: … Re Ob 90 DHA ... Vitaphil 90 DHA ... CitraNatal 90 DHA …
Matched Products: … NATURE'S BOUNTY NATURAL B-6 100 MG TABLET, 100 ADET ... Vitamin B6 100 mg ... PIRIDOXINA 100 MG …
Antilipemic agent that lowers cholesterol and triglycerides. It decreases low density lipoproteins and increases high density lipoproteins.
Approved
Investigational
Matched Synonyms: … 2-(p-(2-(p-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid …
Matched Iupac: … 2-(4-{2-[(4-chlorophenyl)formamido]ethyl}phenoxy)-2-methylpropanoic acid …
Penbutolol is a drug in the beta-blocker class used to treat hypertension. Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker. Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric drug. Penbutolol also demonstrates high binding affinity to the...
Approved
Investigational
Matched Synonyms: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Iupac: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Description: … Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker …
Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is sold under the name "Colazal" in the US and "Colazide" in the UK. The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. It is usually administered as the disodium salt. Balsalazide works by deliverying mesalazine...
Approved
Investigational
Matched Synonyms: … (E)-5-({p-[(2-carboxyethyl)carbamoyl]phenyl}azo)-2-salicylic acid ... (E)-5-((4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid ... 5-[4-(2-carboxy-ethylcarbamoyl)-phenylazo]-2-hydroxy-benzoic acid …
Matched Iupac: … 5-[(1E)-2-{4-[(2-carboxyethyl)carbamoyl]phenyl}diazen-1-yl]-2-hydroxybenzoic acid …
Matched Description: … The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. …
Matched Categories: … Non COX-2 selective NSAIDS …
A semi-synthetic cephalosporin antibiotic.
Approved
Matched Synonyms: … oct-2-ene-2-carboxylic acid ... ]oct-2-ene-2-carboxylic acid ... 7-(D-2-Amino-2-(1,4-cyclohexadienyl)acetamide)desacetoxycephalosporanicacid …
Matched Iupac: … ]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to...
Approved
Investigational
Matched Synonyms: … 4'-((4-methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid ... 4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid ... 4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid …
Matched Iupac: … ]-2-carboxylic acid ... 4'-{[4-methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}-[1,1'-biphenyl …
Matched Mixtures name: … ARMIPIN 80/5MG TABLET, TABLET, 90 ADET ... ARMIPIN 80/2.5MG TABLET, TABLET, 90 ADET ... TRIOTEL 80/10/25 MG TABLET, TABLET, 90 ADET …
Matched Categories: … Angiotensin 2 Receptor Blocker ... Heterocyclic Compounds, 2-Ring ... Angiotensin II Type 2 Receptor Blockers …
Matched Products: … TELPRES 80 MG TABLET, 90 ADET …
A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
Approved
Matched Synonyms: … 5-chloro-2-benzoxazolol ... 5-chloro-2-benzoxazolone ... 5-chloro-2-benzoxazolinone …
Matched Iupac: … 5-chloro-2,3-dihydro-1,3-benzoxazol-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the elongation of DNA chains, thus resulting in the termination of viral DNA growth. The compound is...
Approved
Investigational
Matched Synonyms: … 2',3'-Dideoxycytidine ... 4-amino-1-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2(1H)-one …
Matched Iupac: … 4-amino-1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Propiomazine, an atypical antipsychotic agent, is used to treat both negative and positive symptoms of schizophrenia, acute mania with bipolar disorder, agitation, and psychotic symptoms in dementia. Future uses may include the treatment of obsessive-compulsive disorder and severe behavioral disorders in autism. Structurally and pharmacologically similar to clozapine, propiomazine binds...
Approved
Matched Synonyms: … 10-(2-Dimethylaminopropyl)-2-propionylphenothiazine ... 2-Propionyl-10-(2-(dimethylamino)propyl)phenothiazine …
Matched Iupac: … 1-{10-[2-(dimethylamino)propyl]-10H-phenothiazin-2-yl}propan-1-one …
Matched Description: … to clozapine, propiomazine binds to alpha(1), dopamine, histamine H1, muscarinic, and serotonin type 2
Eprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting norepinephrine production, blood pressure is further reduced.
Approved
Matched Synonyms: … (E)-3-[2-n-butyl-1-{(4-carboxyphenyl)methyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acid ... (E)-2-butyl-1-(p-carboxybenzyl)-α-2-thenylimidazole-5-acrylic acid ... (E)-α{[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazole-5-yl]methylene}-2-thiopheneproprionic acid …
Matched Iupac: … 4-({2-butyl-5-[(1E)-2-carboxy-2-[(thiophen-2-yl)methyl]eth-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic …
Matched Description: … It performs 2 actions on the renin angiotensin system. …
Matched Categories: … Angiotensin 2 Receptor Blocker …
Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased...
Approved
Withdrawn
Matched Synonyms: … (±)-methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate ... methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate ... Methyl 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoate …
Matched Iupac: … methyl 3-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)propanoate …
Matched Products: … İNFÜZYON İÇİN ÇÖZELTİ, 100 ML SETLİ ... İNFÜZYON İÇİN ÇÖZELTİ, 100 ML SETSİZ ... Brevibloc 100 mg/10 ml - Infusionslösung …
Viloxazine is a selective norepinephrine reuptake inhibitor. For decades, an immediate-release formulation of viloxazine has been used in Europe as an antidepressant. It was first approved in the UK in 1974; however, the immediate-release formulation was discontinued due to business reasons unrelated to drug safety and efficacy. In the US,...
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-((2-Ethoxyphenoxy)methyl)morpholine …
Matched Iupac: … 2-[(2-ethoxyphenoxy)methyl]morpholine …
Matched Salts cas: … 35604-67-2
Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. Carprofen was previously used in human medicine for over 10 years (1985-1995). It was generally well tolerated, with the majority of adverse effects being mild,...
Approved
Vet approved
Withdrawn
Matched Synonyms: … 2-(6-Chloro-9H-carbazol-2-yl)-propionic acid ... (±)-6-chloro-α-methylcarbazole-2-acetic acid ... (+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid …
Matched Iupac: … 2-(6-chloro-9H-carbazol-2-yl)propanoic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]
Approved
Matched Synonyms: … 2-(1-piperidinyl)ethyl 3-methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylate ... 2-piperidinoethyl 3-methyl-4-oxo-2-phenyl-4H-1-benzopyran-8-carboxylate ... 2-piperidinoethyl 3-methylflavone-8-carboxylate …
Matched Iupac: … 2-(piperidin-1-yl)ethyl 3-methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylate …
Matched Salts cas: … 3717-88-2
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … สะปาสดิก - 100
Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched Synonyms: … -methyltetrahydrofuran-2-yl)methoxy)- (phenoxy)phosphorylamino)propanoate ... S)-Isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4- dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4 …
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-3-hydroxy ... -4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate …
Matched Description: … a prodrug nucleotide analog, Sofosbuvir is metabolized into its active form as the antiviral agent 2' ... -deoxy-2'-α-fluoro-β-C-methyluridine-5'-triphosphate (also known as GS-461203), which acts as a defective …
Matched Mixtures name: … VOSEVİ 400 MG/ 100 MG/ 100 MG FİLM KAPLI TABLET, 28 ADET ... HARVONI 90 MG/400 MG FILM KAPLI TABLET, 84 ADET ... HARVONI 90 MG/400 MG FILM KAPLI TABLET, 28 ADET …
Cisatracurium is a non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available in its salt form, cisatracurium besylate.[A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly used neuromuscular blocking agents in intensive care.[A253592,A253597]. Cisatracurium acts on cholinergic receptors, blocking neuromuscular transmission. This action is...
Approved
Investigational
Matched Synonyms: … -dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium] ... (1r,2r,1'r,2'r)-2,2'-{pentane-1,5-diylbis[oxy(3-oxopropane-3,1-diyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7 …
Matched Iupac: … -2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium ... -2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium-2-yl]propanoyl}oxy)pentyl]oxy}-3-oxopropyl)-6,7-dimethoxy ... (1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-2-(3-{[5-({3-[(1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Nimbex Injection 2 mg/ml ... นิมเบ็กซ์ (ชนิดฉีด 2 มก./มล.) ... Nimbex 2 mg/ml - Injektions-/Infusionslösung …
Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia. It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient. Sevoflurane was patented in 1972, was approved for clinical use in Japan in 1990, and approved by the FDA in 1996....
Approved
Vet approved
Matched Synonyms: … 1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane …
Matched Iupac: … 1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)propane …
Matched Products: … SEVORANE %100 İNHALASYON ÇÖZELTİSİ, 100 ML ... Sevolox Liquid for Inhalation, 100%v/v ... Sojourn Inhalation Anesthetic Liquid 100% v/v …
Florbetapir (18F) is a radiopharmaceutical compound containing the radionuclide fluorine-18 bound to the compound florbetapir, a molecule that binds with high affinity to beta amyloid plaque, a peptide that plays a key role in Alzheimer's Disease pathogenesis. Marketed as the product Amyvid, florbetapir 18F is indicated for positron emission tomography...
Approved
Investigational
Matched Synonyms: … 4-{(E)-2-[6-(2-{2-[2-(18F)fluoroethoxy]ethoxy}ethoxy)pyridin-3-yl]ethenyl}-N-methylaniline …
Matched Iupac: … 4-[(E)-2-[6-(2-{2-[2-(¹⁸F)fluoroethoxy]ethoxy}ethoxy)pyridin-3-yl]ethenyl]-N-methylaniline …
Displaying drugs 51 - 75 of 11798 in total