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Displaying drugs 51 - 75 of 11608 in total

Guselkumab

Guselkumab is a human immunoglobulin G1 lambda (IgG1λ) monoclonal antibody that selectively blocks interleukin-23. IL-23 is an inflammatory cytokine that activates the CD4+ T-helper (Th17) cell pathway to mediate the inflammatory cascade that induces psoriatic plaque formation . In clinical trials, guselkumab demonstrated improved skin clearance and symptomatic improvements in...
Approved
Investigational
Matched Description: … In clinical trials, guselkumab demonstrated improved skin clearance and symptomatic improvements in dermatological ... Developed by Janssen, the subcutenous injection form of guselkumab was approved in July 2017 under the …
Matched Products: … TREMFYA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML ... TREMFYA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 100MG/1ML …

Chlorhexidine

Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of...
Approved
Vet approved
Withdrawn
Matched Description: … [L11518,L11512,A190453] Chlorhexidine was developed in the UK by Imperial Chemical Industries in the ... early 1950s[A190474] and was introduced to the US in the 1970s. ... Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental …
Matched Mixtures name: … Flamazine C ... Difflam-C Solution ... easyangin Spray zur Anwendung in der Mundhöhle …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Solunet C Brosse 4% ... Chlorhexamed 1% - Gel zur Anwendung in der Mundhöhle ... Chlorhexamed Direkt 1 % - Gel zur Anwendung in der Mundhöhle …

Gadobutrol

Gadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of age. Due to its physicochemical properties, gadobutrol is formulated at twice the gadolinium ion concentration compared to other GBCA and thus requires a lesser...
Approved
Matched Description: … magnetic resonance imaging (MRI) in adults and children older than 2 years of age. ... a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast agent) used in …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Gadograf 1,0 mmol/ml Injektionslösung in Fertigspritzen ... Gadovist 1,0 mmol/ml Injektionslösung in Fertigspritzen/Patronen …

Heparin

Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Description: … UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular ... monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in …
Matched Mixtures name: … Heparin Sodium in Dextrose ... Heparin Sodium in Dextrose ... Heparin Sodium in Dextrose …
Matched Products: … Heparin Sodium in Dextrose ... Heparin Sodium in Sodium Chloride ... Heparin Sodium In Sodium Chloride …

Varicella zoster vaccine (live/attenuated)

Live attenuated zoster vaccine is available as two products: Zostavax for the prevention of shingles in immunocompetent people over the age of 50, and Varivax for the prevention of chickenpox in individuals 12 months of age and older. While the two vaccines contain the same immunological components and provide protection...
Approved
Matched Description: … efficacy in preventing postherpetic neuralgia in patients 70 years and older and 91% efficacy in patients ... Live attenuated zoster vaccine is available as two products: Zostavax for the prevention of shingles in ... immunocompetent people over the age of 50, and Varivax for the prevention of chickenpox in individuals …
Matched Mixtures name: … Priorix - Tetra Pulver in einer Durchstechflasche und Lösungsmittel in einer Fertigspritze zur Herstellung …
Matched Products: … VARIVAX Pulver und Lösungsmittel zur Herstellung einer Injektionssuspension in einer Fertigspritze ... Varilrix Pulver und Lösungsmittel zur Herstellung einer Injektionssuspension in einer Fertigspritze …

Anser anser feather

Anser anser feather is used in allergenic testing.
Approved
Matched Description: … Anser anser feather is used in allergenic testing. …
Matched Mixtures name: … Feather Mix, Chicken/duck/goose …

Benzoic acid

A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid. As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. This leads...
Approved
Investigational
Matched Description: … It is conjugated to GLYCINE in the liver and excreted as hippuric acid. ... This leads to excretion of these amino acids and a decrease in ammonia levels. ... Recent research shows that sodium benzoate may be beneficial as an add-on therapy (1 gram/day) in schizophrenia …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … S Panax All In One Mist …

Oxybuprocaine

Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology. Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions.
Approved
Investigational
Matched Description: … Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology …
Matched Products: … Benoxinat 1% - Lösung zur Anästhesie in der Oto-Rhino-Laryngologie …

Labetalol

Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Products: … Labetalol HCl in Dextrose ... Labetalol HCl in Sodium Chloride …

Abatacept

Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1).[L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Matched Description: … It is produced through recombinant DNA technology in mammalian CHO cells. …
Matched Products: … ORENCIA Injection 125mg/ml in Prefilled Syringe …

Octreotide

Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues and causing metabolic dysfunction. In most cases, it results from an anterior pituitary growth hormone-releasing tumor. Typically, the feet, hands, and face grow abnormally large; organomegaly and insulin resistance may also occur. Acromegaly is...
Approved
Investigational
Matched Description: … [L14513] In the past, octreotide has been administered solely by injection. ... [L14501] In most cases, it results from an anterior pituitary growth hormone-releasing tumor. …
Matched Products: … Siroctid 0,1 mg/ml Injektionslösung in einer Fertigspritze ... Siroctid 0,5 mg/ml Injektionslösung in einer Fertigspritze ... Siroctid 0,05 mg/ml Injektionslösung in einer Fertigspritze …

Esmolol

Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased...
Approved
Withdrawn
Matched Description: … It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate …
Matched Products: … Esmolol Hydrochloride in Water ... Esmolol Hydrochloride In Sodium Chloride …

Gadobenic acid

Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of the liver. It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity....
Approved
Investigational
Matched Description: … Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based ... [A1139] Gadobenate dimeglumine was approved by the FDA in November 2004 under the brand name MultiHance …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … MultiHance 0,5 mmol/ml Injektionslösung in einer Fertigspritze …

Nitroprusside

Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.
Approved
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Sodium Nitroprusside In 0.9% Sodium Chloride …

Human varicella-zoster immune globulin

Human varicella-zoster immune globulin is a solvent/detergent-treated sterile liquid preparation of purified human immune globulin G (IgG) containing antibodies to varicella zoster virus (anti-VZV). It is prepared from pools of healthy human donors' plasma via anion-exchange column chromatography and was approved in 2012 under the name VariZIG to reduce the...
Approved
Matched Description: … from pools of healthy human donors' plasma via anion-exchange column chromatography and was approved in ... 2012 under the name VariZIG to reduce the disease severity in high-risk patients who lack evidence of …

Bivalirudin

Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously. Because it can cause blood stagnation, it is important to monitor changes in...
Approved
Investigational
Matched Description: … Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the ... Because it can cause blood stagnation, it is important to monitor changes in hematocrit, activated partial …
Matched Products: … Bivalirudin in 0.9% Sodium Chloride …

Exenatide

Exenatide is a glucagon-like peptide-1 (GLP-1) analog . It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control . Exenatide was given FDA approval on April 28, 2005 . It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand...
Approved
Investigational
Matched Description: … , was discontinued in 2021. ... [L42685,L42690] Bydureon, the brand name product of extended-release exenatide in an injectable suspension …
Matched Categories: … Drugs Used in Diabetes …
Matched Products: … BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MG …

Hyaluronic acid

Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluronic acid”. HA is involved in many important physiological processes, including but not...
Approved
Vet approved
Matched Description: … neural tissues; it was first isolated in 1934. ... Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and ... HA is involved in many important physiological processes, including but not limited to wound healing, …
Matched Mixtures name: … Le-Blen Vitamin C Serum …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … C-eye Day ... C-eye Night …

Cimetidine

A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Description: … It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant …
Matched Products: … Cimetidine in Sodium Chloride ... DYNAMET TABLET 200MG (F/C) …

Milrinone

Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population. Often the result of long-term myocardial ischemia, cardiomyopathy, or other cardiac insults, heart failure results from an inability of the heart to perfuse peripheral tissues with sufficient oxygen and metabolites, resulting in complex systemic pathologies. Heart...
Approved
Matched Description: … and peripheral vasodilation in acute decongested heart failure. ... Heart failure is underpinned by numerous physiological changes, including alteration in β-adrenergic ... inability of the heart to perfuse peripheral tissues with sufficient oxygen and metabolites, resulting in …
Matched Mixtures name: … Milrinone Lactate in Dextrose …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Milrinone Lactate in Dextrose …

Acetylcysteine

Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Mixtures name: … AMINOPLASMAL 15% IN 500ML GLASS BOTTLE ... ASIST C 600 MG-300 MG TOZ IÇEREN SAŞE,20 SAŞE ... ASIST C 600 MG-300 MG TOZ IÇEREN SAŞE,30 SAŞE …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Sodium phosphate, monobasic

Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.
Approved
Matched Description: … It usually results in a bowel movement after 30 minutes to 6 hours. ... Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine …
Matched Mixtures name: … Utira-C ... UR N-C Urinary Antiseptic ... NUTRIFLEX PLUS IN 1000ML TWIN FLEX …

Conestat alfa

C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase inhibitor (rhC1INH), purified from the milk of transgenic rabbits. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways. It does this through inhibition of several target proteases within...
Approved
Investigational
Matched Description: … Additionally, C4 and C2 cleavage occurs resulting in auto-activation of the complement system. ... Intravenous replacement of C1 esterase inhibitor results in reversal of acute symptoms of HAE. ... Down-stream effects of the lack of enzyme inhibition by C1 esterase inhibitor results in swelling due …
Matched Categories: … Drugs Used in Hereditary Angioedema …

Methenamine

Methenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane. In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine).
Approved
Vet approved
Matched Description: … In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate …
Matched Mixtures name: … All-In-One UTI Emergency Kit ... Utira-C ... Utira-C …

Selenious acid

Selenious acid is the acid form of sodium selenite, a form of selenium . Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties. Selenium is...
Approved
Investigational
Matched Description: … One study showed efficacy in the prevention of malignancy while utilizing a selenium supplement in humans ... studies to validate the results in larger populations [L1918]. ... It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant …
Matched Mixtures name: … Tracel Injektionslösung in einer Fertigspritze ... C. Vit-min Formula ... Vitamins C Plus E W.beta Carotene and Se …
Displaying drugs 51 - 75 of 11608 in total