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Displaying drugs 751 - 775 of 2982 in total

Tirofiban

Tirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery. It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits platelet aggregation.
Approved
Matched Synonyms: … (2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid …
Matched Iupac: … (2S)-2-(butane-1-sulfonamido)-3-{4-[4-(piperidin-4-yl)butoxy]phenyl}propanoic acid …
Matched Description: … It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits …
Matched Salts name: … Tirofiban hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Products: … Tirofiban Hydrochloride ... Tirofiban hydrochloride …

Terazosin

Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label] . Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate .
Approved
Matched Description: … quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and ... adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and …
Matched Salts name: … Terazosin hydrochloride ... Terazosin hydrochloride hydrate …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … Terazosin Hydrochloride ... Terazosin hydrochloride ... Terazosin Hydrochloride Anhydrous …

AVR-RD-05

AVR-RD-05 is a gene therapy comprising genetically modified autologous stem cells transduced ex vivo with a lentiviral vector encoding the human iduronate-2-sulfatase (IDS) enzyme. It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII).
Investigational
Matched Synonyms: … modified autologous cell therapy intended for the stable provision of functional human iduronate-2-sulfatase …
Matched Description: … autologous stem cells transduced _ex vivo_ with a lentiviral vector encoding the human iduronate-2-sulfatase …

Aminosalicylic acid

An antitubercular agent often administered in association with isoniazid. The sodium salt of the drug is better tolerated than the free acid.
Approved
Matched Synonyms: … Aminosalicylic acid ... 4-aminosalicylic acid ... p-aminosalicylic acid …
Matched Name: … Aminosalicylic acid …
Matched Iupac: … 4-amino-2-hydroxybenzoic acid …
Matched Description: … The sodium salt of the drug is better tolerated than the free acid. …
Matched Salts name: … Aminosalicylate calcium ... Aminosalicylate sodium anhydrous ... Sodium aminosalicylate dihydrate ... Calcium aminosalicylate trihydrate …
Matched Categories: … Aminosalicylic Acid and Derivatives ... sodium aminosalicylate ... calcium aminosalicylate ... Acids, Carbocyclic ... Hydroxy Acids …
Matched Products: … SODIUM ( 1G.) ... Nemasol Sodium Tab 500mg ... MONOPAS®GRÁNULOS (PAS SODICO) 60% P/P …

Mexiletine

Antiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.
Approved
Investigational
Matched Salts name: … Mexiletine hydrochloride …
Matched Categories: … Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …
Matched Products: … Mexiletine Hydrochloride ... Mexiletine hydrochloride …

Hydromorphone

Hydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and...
Approved
Illicit
Matched Description: … A176495] The first reported approved product containing hydromorphone in the form of hydromorphone hydrochloride ... the absence of a double bond between the carbon 7 and 8. ... was developed by Fresenius Kabi USA and FDA approved in 1984. …
Matched Salts name: … Hydromorphone sulfate ... Hydromorphone hydrochloride …
Matched Categories: … hydromorphone and naloxone ... hydromorphone and antispasmodics …
Matched Products: … Hydromorphone Hydrochloride ... Hydromorphone hydrochloride ... HYDROmorphone Hydrochloride …

Levobunolol

A nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma.
Approved
Matched Salts name: … Levobunolol hydrochloride …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Levobunolol Hydrochloride ... Levobunolol Hydrochloride Ophthalmic Solution …

Lipoic acid

A vitamin-like antioxidant.
Approved
Investigational
Nutraceutical
Matched Synonyms: … Lipoic acid ... Thioctic acid ... α-lipoic acid …
Matched Name: … Lipoic acid …
Matched Iupac: … 5-[(3R)-1,2-dithiolan-3-yl]pentanoic acid …
Matched Mixtures name: … Folic-K ... Folica-V …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Various Alimentary Tract and Metabolism Products ... Fatty Acids ... Carboxylic Acids …
Matched Products: … ALPHA LIPOIC ACID CAPSULE ... LIPO-X (ALPHA LIPOIC ACID 50MG) ... GNC-ALPHA LIPOIC ACID 100MG …

Calcium oxide

Experimental
Matched Synonyms: … Calcium oxide ... Calcium monoxide ... Lime (calcium oxide) …
Matched Name: … Calcium oxide …

Procaterol

A long-acting beta-2-adrenergic receptor agonist. It is a potent bronchodilator that may be administered orally or by aerosol inhalation.
Approved
Investigational
Matched Salts name: … Procaterol hydrochloride ... Procaterol hydrochloride hemihydrate …
Matched Products: … PROCATEROL HYDROCHLORIDE HEMIHYDRATE …

Phenothiazine

Phenothiazine (PTZ) is an organic thiazine compound.
Experimental
Vet approved
Matched Synonyms: … dibenzo-1,4-thiazine …
Matched Description: … Phenothiazine (PTZ) is an organic thiazine compound. …

Vilazodone

Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. Vilazodone may also be associated with less sexual dysfunction and weight gain . Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].
Approved
Matched Description: … (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. ... Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine ... Vilazodone may also be associated with less sexual dysfunction and weight gain[A6947]. …
Matched Salts name: … Vilazodone hydrochloride …
Matched Categories: … Serotonin antagonist and reuptake inhibitors (SARIs) …
Matched Products: … Vilazodone Hydrochloride ... Vilazodone hydrochloride …

Sodium dichloroacetate

Investigational
Matched Synonyms: … Dca sodium ... Dichloroacetate sodium …
Matched Name: … Sodium dichloroacetate …
Matched Iupac: … sodium 2,2-dichloroacetate …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …

Topotecan

An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Approved
Investigational
Matched Salts name: … Topotecan hydrochloride …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Topotecan hydrochloride ... Topotecan Hydrochloride ... Topotecan Hydrochloride for Injection …

Trimethoprim

Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival. Trimethoprim is often used in combination with sulfamethoxazole due to their...
Approved
Vet approved
Matched Description: … (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival ... L11893] Trimethoprim is often used in combination with [sulfamethoxazole] due to their complementary and ... synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of urinary …
Matched Mixtures name: … POLYMYXIN B SULFATE and TRIMETHOPRIM SULFATE ... POLYMYXIN B SULFATE and TRIMETHOPRIM SULFATE ... POLYMYXIN B SULFATE and TRIMETHOPRIM SULFATE …
Matched Salts name: … Trimethoprim sulfate ... Trimethoprim hydrochloride …
Matched Categories: … Folic Acid Antagonists ... isoniazid, sulfamethoxazole, trimethoprim and pyridoxine ... Trimethoprim and Derivatives ... Sulfonamides and trimethoprim ... sulfametrole and trimethoprim …
Matched Products: … TRIMPEX trimethoprim hydrochloride …

Imipramine

Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts...
Approved
Matched Description: … and clomipramine. ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... than secondary amine TCAs, such as nortriptyline and desipramine. …
Matched Salts name: … Imipramine hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Imipramine Hydrochloride ... Imipramine hydrochloride ... Imipramine Hydrochloride Tablets 25mg …

Nalmefene

Nalmefene, a 6-methylene analogue of naltrexone, is an opioid receptor antagonist. It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist at the kappa (κ)-opioid receptor. In Europe, nalmefene oral tablets are used to reduce alcohol consumption in adults with alcohol dependence. Nalmefene...
Approved
Investigational
Withdrawn
Matched Description: … [L40684] It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist …
Matched Salts name: … Nalmefene hydrochloride ... Nalmefene hydrochloride dihydrate …
Matched Products: … Nalmefene Hydrochloride …

Isoprenaline

Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and cardiogenic shock.[A15638,L33160] Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising...
Approved
Investigational
Matched Description: … anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and ... found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising the heart rate and ... [A233724,A233729] The US patent from 1943 states that this compound had a wider therapeutic index and …
Matched Salts name: … Isoproterenol sulfate ... Isoprenaline hydrochloride …
Matched Categories: … Adrenergic and Dopaminergic Agents ... isoprenaline and other drugs for obstructive airway diseases …
Matched Products: … Isoproterenol Hydrochloride ... Isoproterenol hydrochloride ... Isoproterenol Hydrochloride Injection USP …

Ferric glycerophosphate

Approved
Experimental
Matched Synonyms: … Iron(3+) glycerophosphate …
Matched Iupac: … bis(lambda2-iron(2+)) 3-(phosphonatooxy)pentane-1,5-diol 3-(phosphonatooxy)propane-1,2-diol …

Meperidine

A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Approved
Matched Description: … that can be used for the relief of most types of moderate to severe pain, including postoperative pain and ... lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and …
Matched Mixtures name: … Meperidine Hydrochloride and Promethazine Hydrochloride ... Meperidine Hcl and Promethazine Hcl …
Matched Salts name: … Meperidine hydrochloride …
Matched Categories: … pethidine and antispasmodics ... Acids, Heterocyclic ... Isonipecotic Acids …
Matched Products: … Meperidine Hydrochloride ... Meperidine Hydrochloride Injection USP ... DBL PETHIDINE HYDROCHLORIDE INJECTION BP 50mg/ml …

Naltrexone

Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
Approved
Investigational
Vet approved
Matched Description: … It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and …
Matched Mixtures name: … Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release …
Matched Salts name: … Naltrexone hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... oxycodone and naltrexone ... bupropion and naltrexone …
Matched Products: … Naltrexone Hydrochloride ... Naltrexone Hydrochloride Tablets USP …

Calcium citrate

Calcium citrate is a salt typically used as a source of calcium in a variety of over the counter supplements.
Approved
Investigational
Matched Name: … Calcium citrate …
Matched Description: … Calcium citrate is a salt typically used as a source of calcium in a variety of over the counter supplements …
Matched Mixtures name: … Calcium, Magnesium, Zinc and D ... Calcium and Mag-potass and Zinc Cap ... Nutravite Calcium Magnesium and Zinc Caps …
Matched Salts name: … Calcium citrate malate ... Calcium citrate tetrahydrate …
Matched Categories: … ascorbic acid (vit C) and calcium ... Calcium-Regulating Hormones and Agents ... Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... Calcium Salts …
Matched Products: … Calcium 350 Mg (calcium Citrate) - Caplet ... Calcium 350 Mg (calcium Citrate) Caplet ... Calcium Citrate …

Midazolam

Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by...
Approved
Illicit
Matched Description: … and endoscopic procedures as pre-anesthetic medication, and as an adjunct to local anesthesia. ... short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and ... This drug is unique from others in this class due to its rapid onset of effects and short duration of …
Matched Salts name: … Midazolam hydrochloride …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives ... Hypnotics and Sedatives …
Matched Products: … Midazolam Hydrochloride ... Midazolam hydrochloride ... MIDAZOLAM HYDROCHLORIDE …

Thiamine(1+) monophosphate

Experimental
Matched Name: … Thiamine(1+) monophosphate …

Zinc;[amino-[2-[[5-[amino(azaniumylidene)methyl]benzimidazol-1-id-2-yl]methyl]benzimidazol-1-id-5-yl]methylidene]azanium

Experimental
Matched Synonyms: … bis(5-amidino-benzimidazolyl)methane zinc …
Matched Name: … Zinc;[amino-[2-[[5-[amino(azaniumylidene)methyl]benzimidazol-1-id-2-yl]methyl]benzimidazol-1-id-5-yl] …
Matched Iupac: … zinc(2+) 5-[amino(iminiumyl)methyl]-2-({5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-1-id-2-yl}methyl …
Displaying drugs 751 - 775 of 2982 in total