Displaying drugs 751 - 775 of 2661 in total
Dextropropoxyphene
Dextropropoxyphene is an opioid analgesic manufactured by Eli Lilly and Company. It is used in the symptomatic treatment of mild pain. It displays antitussive and local anaesthetic actions. Due to the risk of cardiac arrhythmias and overdose, possibly leading to death, dextropropoxyphene has been withdrawn from the market in Europe...
Approved
Illicit
Investigational
Withdrawn
Matched Description: … It displays antitussive and local anaesthetic actions. ... Dextropropoxyphene is an opioid analgesic manufactured by Eli Lilly and Company. ... been withdrawn from the market in Europe and the United States. …
Matched Mixtures name: … Propoxyphene Hydrochloride and Acetaminophen ... Propoxyphene Hydrochloride and Acetaminophen ... Propoxyphene Hydrochloride and Acetaminophen …
Matched Salts name: … Dextropropoxyphene hydrochloride …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Products: … Propoxyphene Hydrochloride …
Matched Mixtures name: … Propoxyphene Hydrochloride and Acetaminophen ... Propoxyphene Hydrochloride and Acetaminophen ... Propoxyphene Hydrochloride and Acetaminophen …
Matched Salts name: … Dextropropoxyphene hydrochloride …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Products: … Propoxyphene Hydrochloride …
p-Coumaric acid
Experimental
Matched Synonyms: … 4-coumaric acid ... p-Coumaric acid ... (E)-p-coumaric acid …
Matched Name: … p-Coumaric acid …
Matched Iupac: … (2E)-3-(4-hydroxyphenyl)prop-2-enoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Name: … p-Coumaric acid …
Matched Iupac: … (2E)-3-(4-hydroxyphenyl)prop-2-enoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Vinylsulfonic acid
Experimental
Matched Synonyms: … Vinylsulphonic acid ... Ethylenesulfonic acid …
Matched Name: … Vinylsulfonic acid …
Matched Iupac: … ethenesulfonic acid …
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Matched Name: … Vinylsulfonic acid …
Matched Iupac: … ethenesulfonic acid …
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Carteolol
A beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent.
Approved
Matched Description: … beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and …
Matched Salts name: … Carteolol hydrochloride …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Carteolol Hydrochloride …
Matched Salts name: … Carteolol hydrochloride …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Carteolol Hydrochloride …
Oxogluric acid
Oxogluric acid (α-Ketoglutarate) is not approved for any indication in the world but is an investigational drug in the United States. In the United States a phase I clinical trial is investigating whether oxogluric acid precursors found in nutritional supplements can benefit patients with the metabolic disorder propionic acidemia. Oxogluric...
Experimental
Investigational
Nutraceutical
Matched Synonyms: … 2-Ketoglutaric acid ... 2-oxoglutaric acid ... Ketoglutaric acid …
Matched Name: … Oxogluric acid …
Matched Iupac: … 2-oxopentanedioic acid …
Matched Description: … reactions during the metabolism of amino acids, forms glutamic acid by combining with ammonia, and reduces ... remove excess ammonia, but it is not officially approved for this indication and only experimental studies ... have shown a reduction in ammonia by oxogluric acid in hemodialysis patients. …
Matched Categories: … Keto Acids ... Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids ... Ketoglutaric Acids …
Matched Name: … Oxogluric acid …
Matched Iupac: … 2-oxopentanedioic acid …
Matched Description: … reactions during the metabolism of amino acids, forms glutamic acid by combining with ammonia, and reduces ... remove excess ammonia, but it is not officially approved for this indication and only experimental studies ... have shown a reduction in ammonia by oxogluric acid in hemodialysis patients. …
Matched Categories: … Keto Acids ... Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids ... Ketoglutaric Acids …
Dexrazoxane
An antimitotic agent with immunosuppressive properties. Dexrazoxane, the (+)-enantiomorph of razoxane, provides cardioprotection against anthracycline toxicity. It appears to inhibit formation of a toxic iron-anthracycline complex. [PubChem]
The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and...
Approved
Withdrawn
Matched Description: … prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy. ... [PubChem]
The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the …
Matched Salts name: … Dexrazoxane hydrochloride …
Matched Products: … Dexrazoxane Hydrochloride …
Matched Salts name: … Dexrazoxane hydrochloride …
Matched Products: … Dexrazoxane Hydrochloride …
Guanfacine
Guanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension but is now indicated as an extended release tablet for the treatment of ADHD. Guanfacine was first described in the literature in 1974. Guanfacine was granted FDA approval on 27 October 1986.
Approved
Investigational
Matched Salts name: … Guanfacine hydrochloride …
Matched Categories: … Carboxylic Acids …
Matched Products: … Guanfacine hydrochloride ... Guanfacine Hydrochloride …
Matched Categories: … Carboxylic Acids …
Matched Products: … Guanfacine hydrochloride ... Guanfacine Hydrochloride …
2,2-Dimethylbutyrate
Investigational
Matched Synonyms: … Dimebutic acid ... 2,2-dimethylbutanoic acid ... 2,2-dimethylbutyric acid …
Matched Iupac: … 2,2-dimethylbutanoic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Iupac: … 2,2-dimethylbutanoic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
(R)-Mandelic acid
Experimental
Matched Synonyms: … (−)-mandelic acid ... (−)-(R)-mandelic acid ... D-mandelic acid …
Matched Name: … (R)-Mandelic acid …
Matched Iupac: … (2R)-2-hydroxy-2-phenylacetic acid …
Matched Name: … (R)-Mandelic acid …
Matched Iupac: … (2R)-2-hydroxy-2-phenylacetic acid …
Senna leaf
Approved
Experimental
Matched Synonyms: … Ennae folium ... Sennae folium ... Sennae folium concisum …
Matched Mixtures name: … SENNA LEAF and DOCUSATE SODIUM …
Matched Mixtures name: … SENNA LEAF and DOCUSATE SODIUM …
Thiosalicylic acid
Experimental
Matched Synonyms: … 2-Thiosalicylic acid ... 2-Mercaptobenzoic acid ... o-Benzoic acid thiol …
Matched Name: … Thiosalicylic acid …
Matched Iupac: … 2-sulfanylbenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids …
Matched Name: … Thiosalicylic acid …
Matched Iupac: … 2-sulfanylbenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids …
Procaine
A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in...
Approved
Investigational
Vet approved
Matched Synonyms: … 4-aminobenzoic acid 2-diethylaminoethyl ester ... p-Aminobenzoic acid 2-diethylaminoethyl ester …
Matched Description: … A local anesthetic of the ester type that has a slow onset and a short duration of action. ... It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. …
Matched Salts name: … Procaine hydrochloride …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Acids, Carbocyclic ... Carboxylic Acids ... Esters of Aminobenzoic Acid …
Matched Products: … Procaine Hydrochloride …
Matched Description: … A local anesthetic of the ester type that has a slow onset and a short duration of action. ... It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. …
Matched Salts name: … Procaine hydrochloride …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Acids, Carbocyclic ... Carboxylic Acids ... Esters of Aminobenzoic Acid …
Matched Products: … Procaine Hydrochloride …
Citraconic acid
Citraconic acid is one of the isomeric dicarboxylic acids produced by the distillation of citric acid, or as metabolites by microorganisms, cis-CH3-C(CO2H)=CHCO2H; the trans-isomer is mesaconic acid.
Experimental
Matched Synonyms: … 2-methylmaleic acid ... Methylmaleic acid ... α-methylmaleic acid …
Matched Name: … Citraconic acid …
Matched Iupac: … (2Z)-2-methylbut-2-enedioic acid …
Matched Description: … Citraconic acid is one of the isomeric dicarboxylic acids produced by the distillation of citric acid ... , or as metabolites by microorganisms, cis-CH3-C(CO2H)=CHCO2H; the trans-isomer is mesaconic acid. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Name: … Citraconic acid …
Matched Iupac: … (2Z)-2-methylbut-2-enedioic acid …
Matched Description: … Citraconic acid is one of the isomeric dicarboxylic acids produced by the distillation of citric acid ... , or as metabolites by microorganisms, cis-CH3-C(CO2H)=CHCO2H; the trans-isomer is mesaconic acid. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Foscarnet
An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.
Approved
Matched Synonyms: … Carboxyphosphonic acid ... Phosphonoformic acid ... Phosphonomethanoic acid …
Matched Iupac: … phosphonoformic acid …
Matched Description: … Foscarnet also shows activity against human herpes viruses and HIV. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Phosphonic Acid Derivatives ... Nucleic Acid Synthesis Inhibitors …
Matched Iupac: … phosphonoformic acid …
Matched Description: … Foscarnet also shows activity against human herpes viruses and HIV. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Phosphonic Acid Derivatives ... Nucleic Acid Synthesis Inhibitors …
Dehydrocholic acid
Dehydrocholic acid is a synthetic bile acid that was prepared from the oxidation of cholic acid with chromic acid . It has been used for stimulation of biliary lipid secretion. The use of dehydrocholic acid in over-the-counter products has been discontinued by Health Canada.
Approved
Investigational
Matched Synonyms: … Dehydrocholic acid ... 3,7,12-triketocholanic acid ... 3,7,12-trioxocholanic acid …
Matched Name: … Dehydrocholic acid …
Matched Iupac: … 9aS,9bS,11aR)-9a,11a-dimethyl-4,7,11-trioxo-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … Dehydrocholic acid is a synthetic bile acid that was prepared from the oxidation of cholic acid with ... chromic acid [A33022]. ... The use of dehydrocholic acid in over-the-counter products has been discontinued by Health Canada. …
Matched Categories: … Bile Acids and Salts ... Cholagogues and Choleretics ... Cholic Acids …
Matched Name: … Dehydrocholic acid …
Matched Iupac: … 9aS,9bS,11aR)-9a,11a-dimethyl-4,7,11-trioxo-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … Dehydrocholic acid is a synthetic bile acid that was prepared from the oxidation of cholic acid with ... chromic acid [A33022]. ... The use of dehydrocholic acid in over-the-counter products has been discontinued by Health Canada. …
Matched Categories: … Bile Acids and Salts ... Cholagogues and Choleretics ... Cholic Acids …
Trimesic acid
Experimental
Matched Synonyms: … Trimesinic acid ... Trimesitinic acid ... 5-carboxyisophthalic acid …
Matched Name: … Trimesic acid …
Matched Iupac: … benzene-1,3,5-tricarboxylic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Name: … Trimesic acid …
Matched Iupac: … benzene-1,3,5-tricarboxylic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
PMP-hydroxyisoxazole, pyridoxamine-5-phosphate-hydroxyisoxazole
Experimental
Matched Name: … PMP-hydroxyisoxazole, pyridoxamine-5-phosphate-hydroxyisoxazole …
Matched Iupac: … hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methoxy]phosphonic acid …
Matched Iupac: … hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methoxy]phosphonic acid …
Melphalan
Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Iupac: … (2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanoic acid …
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. …
Matched Salts name: … Melphalan hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Products: … Melphalan Hydrochloride ... Melphalan hydrochloride …
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. …
Matched Salts name: … Melphalan hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Products: … Melphalan Hydrochloride ... Melphalan hydrochloride …
Cyclobenzaprine
Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from Amitriptyline by only a single double bond.[A185039,A184982] Since its approval, it has...
Approved
Matched Description: … Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been …
Matched Salts name: … Cyclobenzaprine hydrochloride …
Matched Products: … Cyclobenzaprine Hydrochloride ... Cyclobenzaprine hydrochloride …
Matched Salts name: … Cyclobenzaprine hydrochloride …
Matched Products: … Cyclobenzaprine Hydrochloride ... Cyclobenzaprine hydrochloride …
3',3-diselenodipropionic acid
Investigational
Matched Synonyms: … Diselenodipropionic acid ... 3',3-diseleno dipropionic acid ... Diseleno-3,3'-dipropionic acid …
Matched Name: … 3',3-diselenodipropionic acid …
Matched Iupac: … 3-[(2-carboxyethyl)diselanyl]propanoic acid …
Matched Name: … 3',3-diselenodipropionic acid …
Matched Iupac: … 3-[(2-carboxyethyl)diselanyl]propanoic acid …
D-Lactic acid
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
Experimental
Matched Synonyms: … (−)-lactic acid ... (R)-lactic acid ... (R)-(−)-lactic acid …
Matched Name: … D-Lactic acid …
Matched Iupac: … (2R)-2-hydroxypropanoic acid …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
Matched Name: … D-Lactic acid …
Matched Iupac: … (2R)-2-hydroxypropanoic acid …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
Phenylpyruvic acid
Experimental
Matched Synonyms: … 3-phenylpyruvic acid ... Phenylpyruvic acid ... β-phenylpyruvic acid …
Matched Name: … Phenylpyruvic acid …
Matched Iupac: … 2-oxo-3-phenylpropanoic acid …
Matched Categories: … Keto Acids ... Carboxylic Acids ... Acids, Carbocyclic …
Matched Name: … Phenylpyruvic acid …
Matched Iupac: … 2-oxo-3-phenylpropanoic acid …
Matched Categories: … Keto Acids ... Carboxylic Acids ... Acids, Carbocyclic …
Tomivosertib
Tomivosertib is under investigation in clinical trial NCT03318562 (A PD Study of Oral eFT508 in Subjects With Advanced TNBC and HCC).
Investigational
Matched Synonyms: … 6'-((6-Amino-4-pyrimidinyl)amino)-8'-methyl-2'H-spiro(cyclohexane-1,3'-imidazo(1,5-a)pyridine)-1',5'- …
Matched Iupac: … 6'-[(6-aminopyrimidin-4-yl)amino]-8'-methyl-2',5'-dihydro-1'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine …
Matched Description: … investigation in clinical trial NCT03318562 (A PD Study of Oral eFT508 in Subjects With Advanced TNBC and …
Matched Salts name: … Tomivosertib hydrochloride …
Matched Iupac: … 6'-[(6-aminopyrimidin-4-yl)amino]-8'-methyl-2',5'-dihydro-1'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine …
Matched Description: … investigation in clinical trial NCT03318562 (A PD Study of Oral eFT508 in Subjects With Advanced TNBC and …
Matched Salts name: … Tomivosertib hydrochloride …
Myristic acid
Experimental
Matched Synonyms: … Tetradecanoic acid ... N-tetradecanoic acid ... N-tetradecan-1-oic acid …
Matched Name: … Myristic acid …
Matched Iupac: … tetradecanoic acid …
Matched Categories: … Fatty Acids ... Myristic Acids …
Matched Name: … Myristic acid …
Matched Iupac: … tetradecanoic acid …
Matched Categories: … Fatty Acids ... Myristic Acids …
Deferiprone
Deferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs. Thalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. As a result, erythropoiesis, the production of new red blood cells, is impaired....
Approved
Matched Synonyms: … 3-Hydroxy-1,2-dimethyl-4(1H)-pyridone …
Displaying drugs 751 - 775 of 2661 in total