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Displaying drugs 801 - 825 of 1934 in total
Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.[L12207,A176173] Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. It is commonly described as an "insulin sensitizer", leading to a decrease in insulin...
Approved
Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by...
Approved
Illicit
Matched Salts cas: … 59467-96-8
Vincristine is an antitumor vinca alkaloid isolated from Vinca Rosea. It is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar. Vincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. vincristine sulfate...
Approved
Investigational
Matched Iupac: … (methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0^{4,12}.0^{5,10}]nonadeca-4(12),5,7,9-tetraen-13-yl]-8- …
Omacetaxine mepesuccinate (formerly known as HHT or Homoharringtonine), is a cephalotaxine ester and protein synthesis inhibitor with established clinical activity as a single agent in hematological malignancies. Omacetaxine mepesuccinate is synthesized from cephalotaxine, which is an extract from the leaves of the plant, Cephalotaxus species. In October 2005, omacetaxine mepesuccinate...
Approved
Investigational
Estradiol is a naturally occurring hormone circulating endogenously in females. It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes. Some available forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and creams.[L11485,L11488,L11491,...
Approved
Investigational
Vet approved
Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Mixtures name: … ENDOFALK TOZ İÇEREN SAŞE, 8 SAŞE …
Isavuconazonium is a second-generation triazole antifungal approved on March 6, 2015 by the FDA and July 2015 by the EMA for the treatment of adults with invasive aspergillosis and invasive mucormycosis, marketed by Astellas under the brand Cresemba. It is the prodrug form of isavuconazole, the active moiety, and it...
Approved
Investigational
Irbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy.[L7456,L7459] It can also be used as part of a combination product with hydrochlorothiazide for patients not well controlled or not expected to be well controlled on monotherapy. Unlike angiotensin converting enzyme inhibitors, ARBs are not associated...
Approved
Investigational
Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described...
Approved
Matched Salts cas: … 345-78-8
Matched Mixtures name: … DUACT 8 MG/60 MG KAPSÜL, 30 ADET …
ENTR-601-44 is an exon 44 skipping phosphorodiamidate morpholino oligonucleotide (PMO). Developed by Entrada Therapeutics, it was investigated for the treatment of Duchenne muscular dystrophy.
Investigational
Matched Name: … ENTR-601-44
Matched Description: … ENTR-601-44 is an exon 44 skipping phosphorodiamidate morpholino oligonucleotide (PMO). …
8-Chloroadenosine is under investigation in clinical trial NCT02509546 (8-chloroadenosine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia).
Investigational
Matched Synonyms: … Adenosine, 8-chloro- …
Matched Name: … 8-Chloroadenosine …
Matched Iupac: … (2R,3R,4S,5R)-2-(6-amino-8-chloro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Description: … 8-Chloroadenosine is under investigation in clinical trial NCT02509546 (8-chloroadenosine in Treating …
8-Chlorotheophylline is a stimulant drug of the xanthine chemical class, with physiological effects similar to caffeine. Its main use is in combination with Diphenhydramine as the antiemetic drug Dimenhydrinate. The stimulant properties of 8-chlorotheophylline are thought to ward off the drowsiness caused by diphenhydramine's anti-histamine activity in the central nervous...
Experimental
Matched Synonyms: … 1,3-dimethyl-8-chloroxanthine ... 8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione …
Matched Name: … 8-chlorotheophylline …
Matched Iupac: … 8-chloro-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Matched Description: … 8-Chlorotheophylline is a stimulant drug of the xanthine chemical class, with physiological effects similar ... anti-histamine activity in the central nervous system. 8-chlorotheophylline produces a number of ... The stimulant properties of 8-chlorotheophylline are thought to ward off the drowsiness caused by diphenhydramine's …
Experimental
Matched Synonyms: … 8-Amino-1,3-dimethyl-3,7-dihydropurine-2,6-dione …
Matched Name: … 8-Aminotheophylline …
Matched Iupac: … 8-imino-1,3-dimethyl-2,3,6,7,8,9-hexahydro-1H-purine-2,6-dione …
8-azaguanine is one of the early purine analogs showing antineoplastic activity. It functions as an antimetabolite and is easily incorporated into ribonucleic acids.
Experimental
Matched Synonyms: … 8 AG ... Azaguanine-8
Matched Name: … 8-azaguanine …
Matched Description: … 8-azaguanine is one of the early purine analogs showing antineoplastic activity. …
Experimental
Matched Synonyms: … 8-Epicobalamine ... Cyano-8-epicobalamin …
Matched Name: … 8-epi-Cyanocobalamin …
Experimental
Matched Synonyms: … 8-OH-Dgmp ... 2'-deoxy-7,8-dihydro-8-oxo-5'-guanylic acid ... 8-hydroxydeoxyguanosine 5'-monophosphate …
Matched Name: … 8-oxo-dGMP …
Experimental
Matched Synonyms: … 8-OHdG ... 8-Oxo-dG ... 8-Oxoguanosine …
Matched Name: … 8-hydroxy-2'-deoxyguanosine …
Matched Iupac: … 2-amino-8-hydroxy-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one …
Interleukin-8 is under investigation in clinical trial NCT05148234 (BMS-986253 in Myelodysplastic Syndromes).
Investigational
Matched Synonyms: … INTERLEUKIN 8 ... INTERLEUKIN 8 (HUMAN) …
Matched Name: … Human Interleukin 8
Matched Description: … Interleukin-8 is under investigation in clinical trial NCT05148234 (BMS-986253 in Myelodysplastic Syndromes …
Matched Categories: … Interleukin-8, antagonists & inhibitors …
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 8 with liver-specific thyroxinebinding globulin (TBG) promoter …
Matched Name: … AAV2/8.TBG.hARSB …
Experimental
Matched Synonyms: … 1-Anilino-8-naphthalenesulfonate ... 1-anilino-8-naphthalenesulfonic acid ... 8-Anilino-1-naphthalene sulfonic acid …
Matched Name: … 8-anilinonaphthalene-1-sulfonic acid …
Matched Iupac: … 8-(phenylamino)naphthalene-1-sulfonic acid …
Experimental
Matched Name: … 8-azaxanthine …
Experimental
Matched Name: … 8-demethyl-8-dimethylamino-flavin-adenine-dinucleotide …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}[({[(2R,3S,4S)-5-[8-(dimethylamino …
Experimental
Matched Name: … 8-iodo-guanine …
Matched Iupac: … 2-amino-8-iodo-6,7-dihydro-3H-purin-6-one …
Experimental
Matched Synonyms: … Ethyl 8-hydroxy-alpha-(2-propynylamino)-5-quinolinepropanoate ... 5-Quinolinepropanoic acid, 8-hydroxy-alpha-(2-propyn-1-ylamino)-, ethyl ester …
Matched Name: … Ethyl 8-hydroxy-alpha-(2-propynylamino)-5-quinolinepropanoate …
Matched Iupac: … ethyl 3-(8-hydroxyquinolin-5-yl)-2-[(prop-2-yn-1-yl)amino]propanoate …
Experimental
Matched Name: … 8-Methyl-9-Oxoguanine …
Displaying drugs 801 - 825 of 1934 in total