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Displaying drugs 801 - 825 of 13918 in total

Ethchlorvynol

Ethchlorvynol is a sedative and hypnotic drug. It has been used to treat insomnia, but has been largely superseded and is only offered where an intolerance or allergy to other drugs exists.
Approved
Illicit
Withdrawn
Matched Synonyms: … 1-chloro-3-ethyl-1-penten-4-yn-3-ol ... 1-Chloro-3-ethyl-pent-1-en-4-yn-3-ol ... 3-(β-chlorovinyl)-1-pentyn-3-ol …
Matched Iupac: … (1E)-1-chloro-3-ethylpent-1-en-4-yn-3-ol …
Matched Description: … Ethchlorvynol is a sedative and hypnotic drug. …

Simeprevir

Simeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor indicated in patient's with HCV genotype 1 for the treatment of chronic hepatitis C virus (HCV) infection. HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United...
Approved
Matched Iupac: … (1R,4R,6R,7Z,15R,17R)-N-(cyclopropanesulfonyl)-17-({7-methoxy-8-methyl-2-[4-(propan-2-yl)-1,3-thiazol ... -2-yl]quinolin-4-yl}oxy)-13-methyl-2,14-dioxo-3,13-diazatricyclo[13.3.0.0^{4,6}]octadec-7-ene-4-carboxamide …
Matched Description: … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... 1 for the treatment of chronic hepatitis C virus (HCV) infection. ... Simeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor indicated in patient's with HCV genotype …
Matched Salts cas: … 1241946-89-3 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …

Mefenamic acid

A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Approved
Matched Synonyms: … N-(2,3-xylyl)-2-aminobenzoic acid ... N-2,3-xylylanthranilic acid …
Matched Iupac: … 2-[(2,3-dimethylphenyl)amino]benzoic acid …
Matched Description: … A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties …

Clodronic acid

Clodronic acid is a first generation bisphosphonate similar to etidronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. clodronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Investigational
Vet approved
Matched Description: … Clodronic acid is a first generation bisphosphonate similar to [etidronic acid] and [tiludronic acid] ... [A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification …

Technetium Tc-99m disofenin

Technetium Tc-99m disofenin is a radiopharmaceutical agent used in hepatobiliary imaging for diagnostic purposes. It is well suited for both planar and single photon tomographic scintigraphy to quantitatively measure the function of liver, gallbladder and bile ducts and detect any anatomical changes in the hepatobliary system. It is available as...
Approved
Matched Iupac: … 2-[({[2,6-bis(propan-2-yl)phenyl]carbamoyl}methyl)(carboxymethyl)amino]acetic acid (99Tc)technetium …
Matched Description: … It is available as an intravenous injection in a preparation kit under the name Hepatolite. ... Technetium Tc-99m disofenin is a radiopharmaceutical agent used in hepatobiliary imaging for diagnostic ... Technetium Tc-99m is a metastable nuclear isomer and disofenin is an iminodiacetic acid derivative with …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Iohexol

Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Approved
Matched Synonyms: … N,N'-Bis(2,3-dihydroxypropyl)-5-(N-(2,3-dihydroxypropyl)acetamido)-2,4,6-triiodoisophthalamide …
Matched Iupac: … N1,N3-bis(2,3-dihydroxypropyl)-5-[N-(2,3-dihydroxypropyl)acetamido]-2,4,6-triiodobenzene-1,3-dicarboxamide …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … KOPAQ 350 MGI/ML ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON ,50 ML -FLAKON, 1 ADET ... KOPAQ 350 MGI/ML ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON ,100 ML -FLAKON, 1 ADET ... KOPAQ 350 MGI/ML ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON ,200 ML -FLAKON, 1 ADET …

Damoctocog alfa pegol

In recent years, various extended half-life factor VIII and factor IX preparations have been studied and gained approval. In order to extend half-lives, techniques such as fusion to protein conjugates (Fc part of IgG1 or albumin), chemical modification (PEGylation), and protein sequence modification have been utilized. Also known as, BAY94-9027,...
Approved
Investigational
Matched Description: … to reduce the number of infusions necessary to prevent bleeds in patients diagnosed with Haemophilia A. ... [L4576,A38909,Label] This product has been engineered by Bayer[L4576] and a biological license application ... [A38907] Also known as, BAY94-9027, Damoctocog alfa pegol is a longer-acting Factor VIII therapy formulated …

Human calcitonin

Calcitonin was first discovered in isolated parathyroid tissue as a substance with a serum-calcium-lowering effect. It is constituted as a 32-amino acid single chain polypeptide structure that gets secreted as a regulatory agent in calcium-phosphorus metabolism. It is used as an alternative for people developing antibodies against salmon calcitonin.
Approved
Investigational
Matched Description: … Calcitonin was first discovered in isolated parathyroid tissue as a substance with a serum-calcium-lowering ... a regulatory agent in calcium-phosphorus metabolism. ... [A32099] It is constituted as a 32-amino acid single chain polypeptide structure that gets secreted as …

Magnesium acetate tetrahydrate

Magnesium acetate tetrahydrate is a hydrated form of anhydrous magnesium acetate salt with the chemical formula of Mg(CH3COO)2 • 4H2O. As a salt form of magnesium, magnesium acetate is one of the bioavailable forms of magnesium and forms a very water soluble compound. Magnesium is an essential element and second...
Approved
Matched Iupac: … magnesium(2+) ion diacetate tetrahydrate …
Matched Description: … formula of Mg(CH3COO)2 • 4H2O. ... a very water soluble compound. ... Magnesium acetate tetrahydrate is a hydrated form of anhydrous magnesium acetate salt with the chemical …
Matched Mixtures name: … Numeta G 16 % E Emulsion zur Infusion ... Nutriflex Omega peri B. Braun Emulsion zur Infusion ... Nutriflex Omega plus B. Braun Emulsion zur Infusion …

Sevoflurane

Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia. It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient. Sevoflurane was patented in 1972, was approved for clinical use in Japan in 1990, and approved by the FDA in 1996....
Approved
Vet approved
Matched Synonyms: … 1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane …
Matched Iupac: … 1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)propane …
Matched Description: … [L42340] It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition ... Unlike other volatile anesthetics, sevoflurane has a pleasant odor and does not irritate the airway. ... [A249910] Therefore, it can be used for inhalational induction in adults and children for a wide variety …
Matched Products: … SEVOFLURANE BAXTER %100 İNHALASYON ÇÖZELTİSİ, 1 ADET …

Fosdenopterin

Molybdenum cofactor deficiency (MoCD) is an exceptionally rare autosomal recessive disorder resulting in a deficiency of three molybdenum-dependent enzymes: sulfite oxidase (SOX), xanthine dehydrogenase, and aldehyde oxidase. Signs and symptoms begin shortly after birth and are caused by a build-up of toxic sulfites resulting from a lack of SOX activity.[A230088,L32163]...
Approved
Matched Description: … In 2009 a recombinant, E. coli-produced cPMP was granted orphan drug designation by the FDA, becoming ... resulting from a lack of SOX activity. ... the first therapeutic option for patients with MoCD type A. …
Matched Categories: … MATE 1 Substrates ... MATE 2 Inhibitors ... Heterocyclic Compounds, 2-Ring …

Antilymphocyte immunoglobulin (horse)

Equine anti-thymocyte globulin is composed of purified gamma globulin containing primarily IgG against human thymus lymphocytes. It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen. The result is polyclonal IgG that...
Approved
Investigational
Matched Description: … system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen. ... It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune ... Although the exact mechanism of action is unknown, equine anti-thymocyte globulin targets a variety of …

Cocaine

An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of...
Approved
Illicit
Matched Synonyms: … methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate ... [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester ... 2-methyl-3β-hydroxy-1αH,5αH-tropane-2β-carboxylate benzoate (ester) …
Matched Iupac: … methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate …
Matched Description: … It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in ... It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse …

Crotalus adamanteus antivenin

Each year it is estimated there are 45,000 snakebites in the US and 300,000 to 400,000 bites worldwide. About 8000 of these snakebites involve venomous snake species. The majority of people bitten are males and about 50% occur in the age group of 18 to 28 . The eastern diamondback...
Approved
Experimental

Distearyldimonium

Approved
Experimental
Matched Salts cas: … 107-64-2 …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Demeclocycline

A tetracycline analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.
Approved
Matched Synonyms: … 12aα)]-7-chloro-4-(dimethylamino)1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2- …
Matched Iupac: … chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2- …
Matched Description: … A tetracycline analog having a 7-chloro and a 6-methyl. …
Matched Salts cas: … 64-73-3 …

Tyloxapol

Tyloxapol is a non-ionic detergent often used as a surfactant.
Approved
Investigational
Matched Description: … Tyloxapol is a non-ionic detergent often used as a surfactant. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

American hazelnut

American hazelnut allergenic extract is used in allergenic testing.
Approved

Opium

Opium is the first substance of the diverse group of the opiates. It has been known for a long time, and the first evidence of a poppy culture dates from 5 thousand years by the Sumerians. During the years, opium was used as a sedative and hypnotic, but it was...
Approved
Illicit
Matched Description: … It has been known for a long time, and the first evidence of a poppy culture dates from 5 thousand years ... During the years, opium was used as a sedative and hypnotic, but it was determined to be addictive. ... Therefore, opium is a sticky brown resin obtained by collecting and drying the latex that exudes from …

Plicamycin

Plicamycin is an antineoplastic antibiotic produced by Streptomyces plicatus. It has been used in the treatment of testicular cancer, Paget's disease of bone, and, rarely, the management of hypercalcemia. The manufacturer discontinued plicamycin in 2000.
Approved
Investigational
Withdrawn
Matched Iupac: … (2S,3S)-3-[(1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-2-{[(2S,4R,5R,6R)-4-{[(2S,4R,5S,6R)-4-{[(2S ... -2-yl]oxy}-8,9-dihydroxy-7-methyl-1,2,3,4-tetrahydroanthracen-1-one ... ,4S,5R,6R)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan ... -2-yl]oxy}-6-{[(2S,4R,5R,6R)-4-{[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Sarecycline

Sarecycline is a semi-synthetic derivative of tetracycline that was initially discovered by Paratek Pharmaceuticals from Boston, MA but then licensed to Warner Chilcott of Rockaway, NJ in July of 2007 . After completing various phase-II and phase-III trials demonstrating its effectiveness in treating moderate to severe facial acne vulgaris [A39993,...
Approved
Investigational
Matched Iupac: … 3,10,12,12a-tetrahydroxy-7-{[methoxy(methyl)amino]methyl}-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2- …
Matched Description: … s Seysara (sarecylcine) as a new first in class narrow spectrum tetracycline derived oral antibiotic ... Sarecycline is a semi-synthetic derivative of tetracycline that was initially discovered by Paratek Pharmaceuticals ... Medical Dermatology portfolio, before Almirall acquired the portfolio in the second half of 2018 as a …
Matched Salts cas: … 1035979-44-2 …

Tolazamide

A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.
Approved
Investigational
Matched Synonyms: … 1-(Hexahydro-1-azepinyl)-3-p-tolylsulfonylurea ... 1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea ... N-(p-Toluenesulfonyl)-N'-hexamethyleniminourea …
Matched Iupac: … 1-(azepan-1-yl)-3-(4-methylbenzenesulfonyl)urea …
Matched Description: … A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide. …

Padeliporfin

Padeliporfin is a water-soluble chlorophyll derivative and cytotoxic photosensitizer used for vascular-targeted photodynamic therapy for malignancies. Vascular-targeted photodynamic therapy (VTP), or vascular targeted photochemotherapy, is a focal treatment for localized prostate cancer. It aims to destroy only cancerous lesions of the prostate, rather than ablating the entire prostate gland. Padeliporfin...
Approved
Experimental
Matched Iupac: … -tetramethyl-20-[(2-sulfoethyl)carbamoyl]-21,22,23,24-tetraazapentacyclo[16.2.1.1^{3,6}.1^{8,11}.1^{13,16 ... palladium(2+) (4S,5S,14R,15R)-10-acetyl-4-(2-carboxyethyl)-15-ethyl-2-(2-methoxy-2-oxoethyl)-5,9,14,19 …
Matched Description: … [A244559] Vascular-targeted photodynamic therapy (VTP), or vascular targeted photochemotherapy, is a ... Padeliporfin is a water-soluble chlorophyll derivative and cytotoxic photosensitizer used for vascular-targeted …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Dabrafenib

Dabrafenib mesylate (Tafinlar) is a reversible ATP-competitive kinase inhibitor and targets the MAPK pathway. It was approved on May 29, 2013, for the treatment of melanoma with V600E or V6000K mutation. It was also used for metastatic non-small cell lung cancer with the same mutation. In May 2018, Tafinlar (dabrafenib),...
Approved
Investigational
Matched Iupac: … N-{3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzene-1- …
Matched Description: … Dabrafenib mesylate (Tafinlar) is a reversible ATP-competitive kinase inhibitor and targets the MAPK …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... B-Raf serine-threonine kinase (BRAF) inhibitors ... Organic Anion Transporter 1 Inhibitors ... Proto-Oncogene Proteins B-raf, antagonists & inhibitors ... P-glycoprotein substrates with a Narrow Therapeutic Index …

Pentoxyverine

Pentoxyverine, also referred to as carbetapentane, is a non-opioid central acting antitussive with antimuscarinic, anticonvulsant , and local anesthetic properties. It is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and H1-receptor antagonists . Pentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors. The...
Approved
Investigational
Withdrawn
Matched Iupac: … 2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopentane-1-carboxylate …
Matched Description: … Pentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors. ... Pentoxyverine, also referred to as carbetapentane, is a non-opioid central acting antitussive with antimuscarinic …
Matched Mixtures name: … Pancold A …
Displaying drugs 801 - 825 of 13918 in total