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Displaying drugs 801 - 825 of 895 in total
GPI-1485
GPI 1485 is a product candidate that belongs to a class of small molecule compounds called neuroimmunophilin ligands.
In preclinical experiments, neuroimmunophilin ligands have been shown to repair and regenerate damaged nerves without affecting normal, healthy nerves.
GPI 1485 is being studied in phase 2 clinical trials for the treatment...
Investigational
Matched Categories: … Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Insulin tregopil
Investigational
Matched Categories: … Cytochrome P-450 CYP1A2 Inducers (strength unknown) …
Tildipirosin
Tildipirosin is a veterinary antibiotic.
Vet approved
Matched Categories: … Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Halometasone
Experimental
Matched Categories: … Cytochrome P-450 CYP3A4 Inducers (strength unknown) ... Cytochrome P-450 CYP3A5 Inducers (strength unknown) …
Mitemcinal
Mitemcinal (GM-611) is a novel erythromycin-derived prokinetic agent that acts as an agonist at the motilin receptor.
Investigational
Matched Categories: … Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Paramethasone
A glucocorticoid with the general properties of corticosteroids. It has been used by mouth in the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary fludrocortisone. (From Martindale, The Extra Pharmacopoeia,...
Experimental
Matched Categories: … Cytochrome P-450 CYP3A4 Inducers (strength unknown) ... Cytochrome P-450 CYP3A5 Inducers (strength unknown) ... Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Benzbromarone
Benzbromarone has been used in trials studying the basic science and treatment of Heart Failure, Hyperuricemia, Chronic Kidney Disease, Abnormal Renal Function, and Gout and Asymptomatic Hyperuricemia.
Investigational
Withdrawn
Matched Categories: … Cytochrome P-450 CYP2C19 inhibitors (strength unknown) ... Cytochrome P-450 CYP2C9 Inhibitors (strength unknown) …
Ditiocarb
A chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM.
Experimental
Matched Categories: … Cytochrome P-450 CYP2E1 Inhibitors (strength unknown) ... Cytochrome P-450 CYP3A5 Inhibitors (strength unknown) …
Quercetin
Quercetin is a flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin.
Experimental
Investigational
Matched Categories: … Cytochrome P-450 CYP2C8 Inhibitors (strength unknown) ... Cytochrome P-450 CYP2C19 inhibitors (strength unknown) ... Cytochrome P-450 CYP2D6 Inhibitors (strength unknown) …
Fluprednidene
Fluprednidene is a corticosteroid.
Experimental
Matched Categories: … Cytochrome P-450 CYP3A4 Inducers (strength unknown) ... Cytochrome P-450 CYP3A5 Inducers (strength unknown) …
9-aminocamptothecin
Aminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others.
Investigational
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates (strength unknown) …
Cortivazol
Cortivazol is under investigation in clinical trial NCT00804895 (Cluster Headache Cortivazol Injection (CHCI)).
Investigational
Matched Categories: … Cytochrome P-450 CYP3A4 Inducers (strength unknown) ... Cytochrome P-450 CYP3A5 Inducers (strength unknown) …
6-Deoxyerythronolide B
Experimental
Matched Categories: … Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Carbomycin
Carbomycin, also called magnamycin, is crystalline macrolide antibiotic. This antibacterial is obtained from Streptomyces halstedii and it presents a large inhibitory effect against Gram-positive bacteria and some Mycoplasma strains. The structure of carbomycin was generated in 1957 by Robert Woodward and later modified in 1965.
Vet approved
Matched Categories: … Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Pranlukast
Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. It antagonizes or reduces bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered allergens.
Investigational
Matched Categories: … Cytochrome P-450 CYP2C9 Inhibitors (strength unknown) ... Cytochrome P-450 CYP3A4 Substrates (strength unknown) …
Barbital
A long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. Barbital is also used in veterinary practice for central nervous system depression. Barbital is a schedule IV controlled drug.
Illicit
Matched Categories: … Cytochrome P-450 CYP2C19 Inducers (strength unknown) ... Cytochrome P-450 CYP3A4 Inducers (strength unknown) …
Kitasamycin
Kitasamycin is a macrolide antibiotic derived from Streptomyces kitasatoensis.
Experimental
Matched Categories: … Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Tesmilifene
Tesmilifene is a novel potentiator of chemotherapy which, when added to doxorubicin, achieved an unexpected and very large survival advantage over doxorubicin alone in a randomized trial in advanced breast cancer.
Investigational
Matched Categories: … Cytochrome P-450 CYP3A4 Inducers (strength unknown) ... Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Prednylidene
Prednylidene is an experimental systemic glucocorticoid.
Experimental
Matched Categories: … Cytochrome P-450 CYP3A4 Inducers (strength unknown) ... Cytochrome P-450 CYP3A5 Inducers (strength unknown) …
Cortisone
A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to the active metabolite hydrocortisone. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)
Experimental
Matched Categories: … Cytochrome P-450 CYP3A4 Inducers (strength unknown) ... Cytochrome P-450 CYP3A5 Inducers (strength unknown) …
KOS-1584
KOS-1584 is a second-generation epothilone. Epothilones are anticancer agents with a taxane-like mechanism of action that have demonstrated activity in taxane-resistant tumors. KOS-1584 is a second-generation compound with increased potency, favorable tissue distribution, and ease of formulation.
Investigational
Matched Categories: … Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Mometasone
Mometasone is a corticosteroid not currently used in medical products. Mometasone furoate however, is still in use.
Experimental
Matched Categories: … Cytochrome P-450 CYP3A4 Inducers (strength unknown) ... Cytochrome P-450 CYP2C8 Inhibitors (strength unknown) ... Cytochrome P-450 CYP3A5 Inducers (strength unknown) …
Epothilone D
Investigational
Matched Categories: … Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Patupilone
Epothilone B is a 16-membered macrolide that mimics the biological effects of taxol.
Experimental
Investigational
Matched Categories: … Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Enrofloxacin
Enrofloxacin is an antibiotic agent from the fluoroquinolone family produced by the Bayer Corporation. Enrofloxacin is approved by the FDA for its veterinary use. Due to the identification of fluoroquinolone-resistant strains of Campylobacter, in September 2005, the FDA withdrew the approval of enrofloxacin for its use in water to treat...
Vet approved
Matched Categories: … Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) …
Displaying drugs 801 - 825 of 895 in total