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Displaying drugs 76 - 100 of 11766 in total
Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin. Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedies
Approved
Matched Synonyms: … 2-Carbamoylphenol ... 2-Hydroxybenzamide ... 2-Carboxamidophenol …
Matched Iupac: … 2-hydroxybenzamide …
Matched Categories: … Non COX-2 selective NSAIDS …
A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.
Approved
Investigational
Matched Synonyms: … alpha-5-norbornen-2-yl-alpha-phenyl-1-piperidinepropanol ... 1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-yl-propan-1-ol ... alpha-bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-1-piperidinepropanol …
Matched Iupac: … 1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenyl-3-(piperidin-1-yl)propan-1-ol …
Matched Salts cas: … 7085-45-2
Matched Products: … BIPERIDEN-NEURAX 2 MG ... AKINETON 2 MG TABLET, 20 ADET ... AKINETON 2 MG TABLET, 50 ADET …
Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. Since the antibiotic, imipenem, is one such antibiotic that is hydrolyzed by dehydropeptidase, cilastatin is used in combination with imipenem to prevent...
Approved
Investigational
Matched Synonyms: … (L)-7-(2-Amino-2-carboxy-ethylsulfanyl)-2-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid ... (Z)-7-((R)-2-Amino-2-carboxy-ethylsulfanyl)-2-[((S)-2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2- …
Matched Iupac: … (2Z)-7-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-2-{[(1S)-2,2-dimethylcyclopropyl]formamido}hept-2-enoic …
Cefmenoxime is a novel broad-spectrum and third-generation cephalosporin antibiotic that is typically used in the treatment of female gynecologic and obstetric infections. It is reported to exhibit high activity against a wide variety of gram-positive and gram-negative bacteria.
Approved
Matched Synonyms: … (6R,7R)-7-((Z)-2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-((1-methyl-1H-5-tetraazolylthio)methyl ... )-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure ... ]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-{[(1-methyl-1H-1,2,3,4-tetrazol ... -5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
A thiol-containing non-essential amino acid that is oxidized to form cystine.
Approved
Nutraceutical
Matched Synonyms: … (2R)-2-amino-3-mercaptopropanoic acid ... (2R)-2-amino-3-sulfanylpropanoic acid ... (R)-2-Amino-3-mercaptopropanoic acid …
Matched Iupac: … (2R)-2-amino-3-sulfanylpropanoic acid …
Matched Mixtures name: … FREAMINE III %10 1000 ML(SETLI) ... FREAMINE III %10 1000 ML(SETSIZ) ... VAMIN GLUKOZ IV SOLÜSYON, 1000 ML …
2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)
Approved
Vet approved
Matched Synonyms: … 4-(2-benzimidazolyl)thiazole ... 2-(thiazol-4-yl)benzimidazole ... 2-(4-thiazolyl)-1H-benzimidazole …
Matched Iupac: … 2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazole …
Matched Description: … 2-Substituted benzimidazole first introduced in 1962. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Cannabidiol, or CBD, is one of at least 85 active cannabinoids identified within the Cannabis plant. It is a major phytocannabinoid, accounting for up to 40% of the Cannabis plant's extract, that binds to a wide variety of physiological targets of the endocannabinoid system within the body. Although the exact...
Approved
Investigational
Matched Synonyms: … (1'R,2'R)-5'-methyl-4-pentyl-2'-(prop-1-en-2-yl)-1',2',3',4'-tetrahydrobiphenyl-2,6-diol ... .DELTA.1(2)-TRANS-CANNABIDIOL ... Δ1(2)-trans-cannabidiol …
Matched Iupac: … 2-[(1R,6R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol …
Matched Description: … mediated through two members of the G-protein coupled receptor family, cannabinoid receptors 1 and 2 ... CB2 receptors, there is further evidence that CBD also activates 5-HT1A/2A/3A serotonergic and TRPV1–2 ... demonstrates its effects through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2
Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying etiology and presentation, including neutropenia and thrombocytopenia. Further mutations leading to increased proliferation of cancerous cells can eventually lead to secondary acute myeloid leukemia, which has a poor prognosis.[A215082, A215092] Among treatment options, nucleoside analogues such as...
Approved
Investigational
Matched Synonyms: … 4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-s-triazin-2(1H)-one ... 5-aza-2'-deoxycytidine …
Matched Iupac: … 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one …
Valine is a branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.
Approved
Nutraceutical
Matched Synonyms: … 2-Amino-3-methylbutyric acid ... (2S)-2-Amino-3-methylbutanoic acid …
Matched Iupac: … (2S)-2-amino-3-methylbutanoic acid …
Matched Mixtures name: … AMINOMIX 2 NOVUM 1000 ML ... AMINOMIX 2 SOLÜSYON, 1000 ML ... AMINOMIX 2 NOVUM 1500 ML …
Nicorandil is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia, most of Europe, India, Philippines, Japan, South Korea, and Taiwan. It is not an approved drug by FDA. It is a niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by activating potassium...
Approved
Investigational
Matched Synonyms: … 2-Nicotinamidoethyl nitrate ... N-(2-Hydroxyethyl)nicotinamide nitrate ... N-(2-Hydroxyethyl)nicotinamide nitrate (ester) …
Matched Iupac: … 2-[(pyridin-3-yl)formamido]ethyl nitrate …
Cidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. It suppresses CMV replication through selective inhibition of viral DNA synthesis.[FDA label] It was manufactured by Gilead and initially approved by the FDA in 1996, but has since been discontinued.
Approved
Matched Synonyms: … (S)-(3-(4-amino-2-Oxopyrimidin-1(2H)-yl)-1-hydroxypropan-2-yloxy)methylphosphonic acid ... ({[(S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid ... [(S)-2-(4-Amino-2-oxo-2H-pyrimidin-1-yl)-1-hydroxymethyl-ethoxymethyl]-phosphonic acid …
Matched Iupac: … ({[(2S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid …
Tolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm. It is sold under several brand names, most notably Tinactin and Odor Eaters.
Approved
Investigational
Vet approved
Matched Synonyms: … 2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate ... O-2-Naphthyl m,N-dimethylthiocarbanilate ... m,N-Dimethylthiocarbanilic acid O-2-naphthyl ester …
Matched Iupac: … N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide …
Matched Products: … ครีมโทนาฟ 2% ... Opti-Nail 2-in-1 …
Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent. It is administered by the intravenous, epidural and sublingual routes. Also known as Dsuvia, the sublingual form is used for the management of acute pain in adults that...
Approved
Investigational
Matched Synonyms: … N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilide ... N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-N-phenylpropanamide …
Matched Iupac: … N-[4-(methoxymethyl)-1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl]-N-phenylpropanamide …
Matched Description: … (AcelRx), was approved on November 2, 2018 [L4717]. …
A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
Approved
Vet approved
Matched Synonyms: … 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone …
Matched Iupac: … 1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one …
A semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative microorganisms.
Approved
Matched Synonyms: … -5- yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2- carboxylic acid ... (6R,7S)-7-(4-(carbamoylcarboxymethylene)-1,3-dithiethane-2-carboxamido)-7-methoxy-3-(((1-methyl-1H-tetrazol …
Matched Iupac: … -tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7S)-7-{4-[carbamoyl(carboxy)methylidene]-1,3-dithietane-2-amido}-7-methoxy-3-{[(1-methyl-1H-1,2,3,4 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Cefotan Injection - 2 G …
Emedastine is an antihistamine used in eye drops to treat allergic conjunctivitis.
Approved
Matched Synonyms: … 1-(2-Ethoxy-ethyl)-2-(4-methyl-[1,4]diazepan-1-yl)-1H-benzoimidazole ... 1-[2-(ethoxy)ethyl]-2-(4-methyl-1-homopiperazinyl)benzimidazole ... 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzimidazole …
Matched Iupac: … 1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-1,3-benzodiazole …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Florbetaben is a fluorine-18 (18F)-labeled stilbene derivative used for Positron Emission Tomography (PET) imaging of the brain. It is used for the non-invasive detection of the density of ß-amyloid neuritic plaques in the brain of adult patients with cognitive impairment.
Approved
Matched Synonyms: … 4-((1E)-2-(4-(2-(2-(2-((SUP 18(F))FLUOROETHOXY)ETHOXY)ETHOXY)PHENYL)ETH-1-EN-1-YL)-N-METHYLANILINE …
Matched Iupac: … 4-[(E)-2-[4-(2-{2-[2-(¹⁸F)fluoroethoxy]ethoxy}ethoxy)phenyl]ethenyl]-N-methylaniline …
Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic...
Approved
Matched Synonyms: … 2-Chloro-m-xylenol ... 2-chloro-5-hydroxy-m-xylene ... 2-chloro-5-hydroxy-1,3-dimethylbenzene …
Matched Mixtures name: … Multi-action Denorex 2-IN-1 Dandruff Shampoo + Conditioner …
Matched Products: … Ps-1000 ... Bm-1000 - Lot 0.25% ... Suite Scrub 1000 Liq 3% …
Sotorasib, also known as AMG-510, is an acrylamide-derived KRAS inhibitor developed by Amgen.[A187547,A187556] It is indicated in the treatment of adult patients with KRAS G12C mutant non-small cell lung cancer. This mutation makes up >50% of all KRAS mutations. Mutant KRAS discovered in 1982 but was not considered a druggable...
Approved
Investigational
Matched Synonyms: … 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-(1M)-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]-4-[(2S)-2- methyl ... -4-(prop-2-enoyl)piperazin-1-yl]pyrido[2,3-d]pyrimidin-2(1H)-one …
Matched Iupac: … 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]-4-[(2S)-2-methyl-4-(prop ... -2-enoyl)piperazin-1-yl]-1H,2H-pyrido[2,3-d]pyrimidin-2-one …
One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
Approved
Nutraceutical
Matched Synonyms: … 2-Aminosuccinic acid ... (S)-2-aminosuccinic acid ... (S)-2-aminobutanedioic acid …
Matched Iupac: … (2S)-2-aminobutanedioic acid …
Matched Mixtures name: … VAMIN GLUKOZ IV SOLÜSYON, 1000 ML ... VAMIN 18 EF AMINOASIT SOLÜSYONU, 1000 ML ... NUMETA PED G 19 % E INFÜZYON IÇIN EMÜLSIYON, 1000 ML …
A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders (From AMA Drug Evaluations Annual, 1994, p311). Tranylcypromine is a racemate comprising...
Approved
Investigational
Matched Synonyms: … (±)-trans-2-phenylcyclopropylamine ... trans-2-phenylcyclopropylamine ... trans-DL-2-Phenylcyclopropylamine …
Matched Iupac: … 2-phenylcyclopropan-1-amine …
Matched Description: … Tranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1- …
Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus. Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects.
Approved
Investigational
Matched Synonyms: … 2'-Deoxy-L-thymidine ... β-L-2'-deoxythymidine ... 1-(2-deoxy-β-L-ribofuranosyl)-5-methyluracil …
Matched Iupac: … 1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.
Approved
Matched Synonyms: … 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate ... 2-phenyl-2-(1-hydroxycyclopentyl)ethanoic acid β-(dimethylamino)ethyl ester ... 2-(dimethylamino)ethyl 1-hydroxy-α-phenylcyclopentaneacetate …
Matched Iupac: … 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate …
A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
Approved
Investigational
Matched Synonyms: … (-)-2'-Deoxy-3'-thiacytidine ... 2',3'-Dideoxy-3'-thiacytidine ... 3'-Thia-2',3'-dideoxycytidine …
Matched Iupac: … 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one …
Matched Mixtures name: … TRIUMEQ 50 MG/600 MG/300 MG FILM KAPLI TABLET,90 FILM KAPLI TABLET …
A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
Approved
Matched Synonyms: … N,N-Dimethyl-2-(alpha-2-tolylbenzoyloxy)ethylamine ... 2-methyldiphenhydramine ... 2-(phenyl-o-tolylmethoxy)ethyldimethylamine …
Matched Iupac: … dimethyl({2-[(2-methylphenyl)(phenyl)methoxy]ethyl})amine …
Displaying drugs 76 - 100 of 11766 in total