Advanced Filter

Filter by Group

Filter by Market Availability

Did you mean 1,5 5r 1?
Displaying drugs 76 - 100 of 12707 in total
A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
Approved
Matched Synonyms: … 1-hexyldecanoic acid ... 1-Pentadecanecarboxylic acid …
Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label]. Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed cell death) process , . Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types...
Approved
Investigational
Matched Synonyms: … -4-{[(oxan-4-yl)methyl]amino}benzene-1-sulfonyl)-2-[(1H-pyrrolo[2,3-b]pyridin-5-yl)oxy]benzamide ... -2H-pyran-4-ylmethyl)amino)phenyl)sulfonyl)-2-(1H-pyrrolo(2,3-b)pyridin-5-yloxy)benzamide ... -2H-pyran-4-ylmethyl)amino]phenyl}sulfonyl)-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide …
Matched Iupac: … 4-yl)methyl]amino}benzenesulfonyl)-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzamide ... 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-(3-nitro-4-{[(oxan- …
Matched Products: … VENCLYXTO 50 MG FILM KAPLI TABLET, 5 ADET …
Ceftolozane is a semi-synthetic broad-spectrum fifth generation cephalosporin. It was approved by the FDA in 2014 for use in combination with Tazobactam for the treatment of serious infections, such as intra-abdominal infections and complicated urinary tract infections. The manufacturer of this drug is Cubist Pharmaceuticals. Most recently, in June 2019,...
Approved
Investigational
Matched Synonyms: … (6R,7R)-3-([3-Amino-4-(2-aminoethylcarbamoylamino)-2-methylpyrazol-1-ium-1-yl]methyl)-7-([(2Z)-2-(5-amino ... -1,2,4-thiadiazol-3-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino)-8-oxo-5-thia-1-azabicyclo[4.2.0 …
Matched Iupac: … 5-amino-2-{[(6R,7R)-7-[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido ... ]-2-carboxylato-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-4-{[(2-aminoethyl)carbamoyl]amino ... }-1-methyl-1H-pyrazol-2-ium …
Matched Mixtures name: … ZERBAXA ® 1 G/0.5 G ... ZERBAXA ® 1 G/0.5 G ... ZERBAXA 1 G/0.5 G INFÜZYONLUK KONSANTRE ÇÖZELTI HAZIRLAMAK IÇIN TOZ IÇEREN FLAKON, 10 FLAKON …
In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Synonyms: … 1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl) …
Matched Iupac: … 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin …
Matched Description: … breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5
Matched Categories: … Phosphodiesterase 5 Inhibitors …
Matched Products: … VEGIRO 100 MG FILM TABLET,1 ADET ... Sildenafil R ... PMS-sildenafil R
A nitroimidazole antitrichomonal agent effective against Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia infections.
Approved
Investigational
Matched Synonyms: … 1-(2-(Ethylsulfonyl)ethyl)-2-methyl-5-nitroimidazole …
Matched Iupac: … 1-[2-(ethanesulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … TINIDAZOL 1 G ... TINIDAZOL 1 G TABLETAS ... ZOLTIFAR® 1 G TABLETAS …
Mitotane is an adrenolytic isomer of the insecticide dichlorodiphenyldichloroethane (DDD) - itself a metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and their production of hormones. It has been in use since 1959 for the treatment of inoperable adrenocortical carcinoma and is used off-label for the...
Approved
Matched Synonyms: … 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]-benzene …
Matched Iupac: … 1-chloro-4-[2,2-dichloro-1-(2-chlorophenyl)ethyl]benzene …
Lumacaftor is a drug used in combination with DB08820 as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic...
Approved
Matched Synonyms: … 3-(6-{[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … from baseline with more than 70% of patients failing to achieve an absolute improvement of at least 5% ... [A18395] The next most common mutation, G551D, affecting 4-5% of CF patients worldwide, is characterized …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Epinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been...
Approved
Vet approved
Matched Synonyms: … 1,2-BENZENEDIOL, 4-(1-HYDROXY-2-(METHYLAMINO)ETHYL)-, (R)- ... 4-((1R)-1-HYDROXY-2-(METHYLAMINO)ETHYL)-1,2-BENZENEDIOL ... 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol …
Matched Iupac: … 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol …
Matched Mixtures name: … ARTHEEK(R) ARTICAINA AL 4% CON EPINEFRINA 1:100.000 ... Septanest mit Epinephrin 1:200.000 40 mg/ml + 5 Mikrogramm/ml Injektionslösung ... Sensorcaine(r) (bupivacaine Hci and Epinephrine) …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists ... Adrenergic beta-1 Receptor Agonists …
Matched Products: … Adrenalin(r) ... ADRENALIN BIOFARMA 1 MG/1 ML, 10 AMPUL ... ADRENALIN BIOFARMA 1 MG/1 ML 100 AMPUL …
Empagliflozin is an inhibitor of sodium-glucose co-transporter-2 (SGLT2), the transporters primarily responsible for the reabsorption of glucose in the kidney. It is used clinically as an adjunct to diet and exercise, often in combination with other drug therapies,[L13673,L13679,L11479] for the management of type 2 diabetes mellitus. The first known inhibitor...
Approved
Matched Synonyms: … 1-chloro-4-(glucopyranos-1-yl)-2-(4-(tetrahydrofuran-3-yloxy)benzyl)benzene ... (1S)-1,5-anhydro-1-(4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl)-D-glucitol …
Matched Mixtures name: … ./5 มก. ... ./5 มก. ... GLYXAMBI® 25 MG/ 5 MG …
Nefazodone hydrochloride (trade name Serzone) is an antidepressant drug marketed by Bristol-Myers Squibb. Its sale was discontinued in 2003 in some countries, due to the small possibility of hepatic (liver) injury. Drug-induced hepatic injuries were associated with an risk of elevated need for a liver transplant, or even death, with...
Approved
Withdrawn
Matched Synonyms: … 1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3-ethyl-4-(2-phenoxyethyl)-delta2-1,2,4-triazolin-5-one …
Matched Iupac: … -5-one ... 1-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-3-ethyl-4-(2-phenoxyethyl)-4,5-dihydro-1H-1,2,4-triazol …
Matched Description: … transplant, or even death, with the incidence of severe liver damage was shown to be approximately 1
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 1-Ring ... Serotonin 5-HT1 Receptor Antagonists ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT1A Receptor Antagonists …
Lormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia . It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations.
Approved
Matched Synonyms: … 7-Chloro-1,3-dihydro-5-(o-chlorophenyl)-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one ... 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one …
Matched Iupac: … 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Description: … It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations. …
Matched Products: … LORMETAZEPAM FARMA 1 ... NOCTAMID 1 TABLETTEN …
Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. It also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts. As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce labour.
Approved
Matched Synonyms: … (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid ... (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid ... (5Z,11α,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid …
Matched Iupac: … (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic acid …
Matched Products: … PROPESS OVUL 10 MG OVUL, 1 ADET …
Approved
Matched Synonyms: … 1-allyl-6-amino-3-ethyluracil …
Proguanil is a prophylactic antimalarial drug, which works by stopping the malaria parasite, Plasmodium falciparum and Plasmodium vivax, from reproducing once it is in the red blood cells. It does this by inhibiting the enzyme, dihydrofolate reductase, which is involved in the reproduction of the parasite.
Approved
Matched Synonyms: … 1-(p-Chlorophenyl)-5-isopropylbiguanide …
Matched Iupac: … 1-[N'-(4-chlorophenyl)carbamimidamido]-N-(propan-2-yl)methanimidamide …
Matched Salts cas: … 637-32-1
An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of...
Approved
Matched Synonyms: … 6-Methoxy-8-(4-amino-1-methylbutylamino)quinoline ... 8-(4-Amino-1-methylbutylamino)-6-methoxyquinoline ... 8-((4-Amino-1-methylbutyl)amino)-6-methoxyquinoline …
Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures[A186277,A186143] - today it is also widely used to treat neuropathic...
Approved
Investigational
Matched Synonyms: … 1-(Aminomethyl)cyclohexaneacetic acid …
Matched Iupac: … 2-[1-(aminomethyl)cyclohexyl]acetic acid …
Matched Mixtures name: … Innoprax-5
Matched Products: … NERUDA 250 MG/5 ML ORAL COZELTI, 470 ML ... GEMUDA 250MG/5ML ORAL ÇÖZELTI, 470 ML, 1 ŞIŞE ... EVEPTIN 250MG/5ML ORAL ÇÖZELTI, 470 ML, 1 ŞIŞE …
Tipiracil is a thymidine phosphorylase inhibitor. It is used in combination with trifluridine, in a ratio of 1:0.5, to form TAS-102. The main function of Tipiracil in TAS-102 is to increase trifluridine bioavailability by inhibiting its catabolism. TAS-102 is indicated for the treatment of metastatic colorectal cancer which has been...
Approved
Investigational
Matched Synonyms: … 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1H,3H)-pyrimidinedione ... 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1H-pyrimidine-2,4-dione …
Matched Iupac: … 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … It is used in combination with trifluridine, in a ratio of 1:0.5, to form TAS-102. …
Matched Categories: … MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring ... MATE 1 Substrates with a Narrow Therapeutic Index …
Oxiconazole is an antifungal agent that is commonly found in topical formulations. It is marketed under the brand names Oxistat and Oxistat, and is used in the treatment of various skin infections such as athlete's foot, jock itch and ringworm.
Approved
Matched Synonyms: … 2',4'-Dichloro-2-imidazol-1-ylacetophenone (Z)-[O-(2,4-dichlorobenzyl)oxime] …
Matched Iupac: … (Z)-[1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethylidene][(2,4-dichlorophenyl)methoxy]amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … OXEZOLE %1 KREM, 20 G ... OCERAL %1 KREM, 10 G ... OXEZOLE %1 KREM, 10 G …
Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
Approved
Investigational
Vet approved
Matched Synonyms: … (±)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid ... 1,3,4,9-tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid ... 1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid …
Matched Iupac: … 2-{1,8-diethyl-1H,3H,4H,9H-pyrano[3,4-b]indol-1-yl}acetic acid …
Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described...
Approved
Matched Synonyms: … (+) threo-2-(methylamino)-1-phenyl-1-propanol ... d-psi-2-Methylamino-1-phenyl-1-propanol …
Matched Iupac: … (1S,2S)-2-(methylamino)-1-phenylpropan-1-ol …
Matched Mixtures name: … COLDFEN 100 MG+15 MG+1 MG/5 ML ŞURUP, 100 ML ... BIKARAMIN COLD 100/15/1 MG/ 5 ML ŞURUP, 100 ML ... COLDAWAY PLUS 100 MG + 15 MG + 1 MG/5 ML ŞURUP, 100 ML …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists …
Matched Products: … Pulmosirum 5 Tab 60mg ... EKSOFED 30 MG/5 ML ŞURUP, 150 ML ... RINOGEST 30 MG/5 ML ŞURUP, 100 ML …
Novartis' brand name Zelnorm (tegaserod) had originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with constipation (IBS-C).[L5918,F4229] It was, however, voluntarily withdrawn from widespread use in the US market in 2007 after concerns arose over the possibility that tegaserod could potentially cause...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-(((5-Methoxyindol-3-yl)methylene)amino)-3-pentylguanidine …
Matched Iupac: … N'-[(E)-[(5-methoxy-1H-indol-3-yl)methylidene]amino]-N-pentylguanidine …
Matched Description: … the only therapy for IBS-C that possesses the unique mechanism of action of acting on serotonin-4 (5- …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
Approved
Matched Synonyms: … 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl) -2- {[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino} -2- oxoethylidene ... (Z,)-2-((((2-Amino-4-thiazolyl)(((2S,3S,)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino …
Matched Iupac: … -4-oxoazetidine-1-sulfonate ... (2S,3S)-3-[(2Z)-2-(2-azaniumyl-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido]-2-methyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … AZACTAM ® 1 G ... Azactam 1 g - Trockenstechampulle ... AZACTAM FOR INJECTION 1 g/vial …
Butoconazole is an imidazole antifungal used in gynecology.
Approved
Matched Synonyms: … 1-[4-(4-Chloro-phenyl)-2-(2,6-dichloro-phenylsulfanyl)-butyl]-1H-imidazole …
Matched Iupac: … 1-[4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)sulfanyl]butyl]-1H-imidazole …
Matched Salts cas: … 64872-77-1
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Gynazole-1 ... Gynazole 1 ... Gynazole.1
Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Synonyms: … 4-amino-1-hydroxybutane-1,1-diphosphonic acid ... (4-amino-1-hydroxybutylidene)bisphosphonic acid ... (4-amino-1-hydroxybutane-1,1-diyl)bis(phosphonic acid) …
Matched Iupac: … (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid …
Matched Salts cas: … 121268-17-5
Matched Products: … Alendronate-5 ... ADROMAX 5 MG TABLET,28 ADET ... ADROMAX 5 MG TABLET,56 ADET …
A phenol obtained from thyme oil or other volatile oils. It is used as a stabilizer in pharmaceutic preparations. It has been used for its antiseptic, antibacterial, and antifungal actions, and was formerly used as a vermifuge. (Dorland, 28th ed)
Approved
Matched Synonyms: … 5-Methyl-2-(1-Methylethyl)Phenol ... 2-isopropyl-5-methylphenol …
Matched Iupac: … 5-methyl-2-(propan-2-yl)phenol …
Matched Mixtures name: … VICKS VAPORUB BUHARLASAN MERHEM, 1 ADET …
Displaying drugs 76 - 100 of 12707 in total