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Displaying drugs 76 - 100 of 10312 in total

Maprotiline

Maprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs). Similar to TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and does not affect monoamine oxidase activity. It differs from TCAs in that it does not appear to block serotonin reuptake. Maprotiline may be used...
Approved
Investigational
Matched Categories: … Antidepressive Agents ... Antidepressive Agents, Tetracyclic ... Antidepressive Agents, Second-Generation ... Antidepressive Agents Indicated for Depression ... Adrenergic Agents …

Desoximetasone

A topical anti-inflammatory glucocorticoid used in dermatoses, skin allergies, psoriasis, etc.
Approved
Matched Categories: … Corticosteroids, Potent (Group III) ... Anti-Inflammatory Agents ... Immunosuppressive Agents …

Ketamine

Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor...
Approved
Vet approved
Matched Description: … It was FDA approved in 1970, and from there, it has been used as an anesthetic for children or patients ... Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. …
Matched Categories: … Agents producing tachycardia ... Vasodilating Agents ... Sensory System Agents ... Neurotransmitter Agents ... Central Nervous System Agents …

Isopropyl myristate

Isopropyl myristate is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption. Isopropyl myristate has been largely studied and impulsed as a skin penetration enhancer. At the moment the primary usage for which isopropyl myristate is formally indicated is as the active...
Approved
Experimental

Testosterone enanthate

Testosterone enanthate is an esterified variant of testosterone that comes as an injectable compound with a slow-release rate. This slow release is achieved by the presence of the enanthate ester functional group attached to the testosterone molecule. This testosterone derivative was first approved on December 24, 1953. In 2017, about...
Approved
Matched Description: … Testosterone enanthate is an esterified variant of testosterone that comes as an injectable compound ... This slow release is achieved by the presence of the enanthate ester functional group attached to the ... As recent as 1 October 2018, the US FDA approved Antares Pharma Inc.' …
Matched Categories: … Contraceptive Agents, Male …

Adenosine phosphate

Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.
Approved
Investigational
Nutraceutical
Withdrawn
Matched Description: … Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified ... the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an …

Raltitrexed

Raltitrexed (brand name Tomudex®) is a chemotherapy drug manufactured AstraZeneca Company, is an antimetabolite used in chemotherapy. It is an inhibitor of thymidylate synthase.
Approved
Investigational
Matched Description: … It is an inhibitor of thymidylate synthase. ... Raltitrexed (brand name Tomudex®) is a chemotherapy drug manufactured AstraZeneca Company, is an …
Matched Categories: … Antineoplastic Agents ... Myelosuppressive Agents ... Immunosuppressive Agents ... Antineoplastic and Immunomodulating Agents …

Mivacurium

Mivacurium is a bisbenzylisoquinolinium based neuromuscular blocker or muscle relaxant. It binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in a block of neuromuscular transmission.
Approved
Matched Categories: … Cholinergic Agents ... Anticholinergic Agents ... Neuromuscular Agents ... Agents producing tachycardia ... Neuromuscular Blocking Agents …

Halcinonide

Halcinonide is a corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, and is distributed as a cream and ointment. Halcinonide is marketed under the brand name Halog® by Ranbaxy Laboratories Inc. Research suggests that clobetasol propionate demonstrates superior pharmacologic efficacy in the treatment of...
Approved
Investigational
Withdrawn
Matched Categories: … Corticosteroids, Very Potent (Group IV) ... Anti-Inflammatory Agents ... Immunosuppressive Agents …

Eravacycline

Eravacycline, known as Xerava by Tetraphase Pharmaceuticals, is a fully synthetic fluorocycline antibiotic of the tetracycline class with activity against clinically significant gram-negative, gram-positive aerobic, and facultative bacteria. This includes most of those bacteria resistant to cephalosporins, fluoroquinolones, β-lactam/β-lactamase inhibitors, multidrug-resistant strains, and carbapenem-resistant Enterobacteriaceae, and the majority of anaerobic...
Approved
Investigational
Matched Description: … It was first approved by the FDA on August 27, 2018 [L4540]. …
Matched Categories: … Anti-Bacterial Agents …

Vibrio cholerae CVD 103-HgR strain live antigen

Vibrio cholerae CVD 103-HgR strain live antigen is a component of Vaxchora, an oral vaccine for immunization against Vibrio cholerae serogroup O1. Cholera is an acute bacterial disease of the small intestine caused by Vibrio cholerae, which is gram-negative bacteria. Two serogroups of V. cholerae, O1 and O139, are causative...
Approved
Investigational
Matched Description: … Two serogroups of _V. cholerae_, O1 and O139, are causative agents of epidemic cholera. ... [A244494] Vaxchora was later approved by the European Commission in April 2020. ... _Vibrio cholerae_ CVD 103-HgR strain live antigen is a component of Vaxchora, an oral vaccine for immunization …

Streptokinase

Streptokinase, is a sterile, purified preparation of a bacterial protein elaborated by group C (beta) -hemolytic streptococci.
Approved
Investigational
Matched Description: … Streptokinase, is a sterile, purified preparation of a bacterial protein elaborated by group C (beta) …
Matched Categories: … Hematologic Agents ... Hypotensive Agents ... Agents causing angioedema ... Fibrinolytic Agents ... Cardiovascular Agents …

Tolmetin

A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.
Approved
Matched Description: … A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of …
Matched Categories: … Nephrotoxic agents ... Antirheumatic Agents ... Anti-Inflammatory Agents ... Agents causing hyperkalemia ... Sensory System Agents …

Tofacitinib

Tofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function. It is approved by the FDA for treatment of moderate to severe rheumatoid arthritis that responds inadequately to methotrexate or in those who are intolerant to methotrexate....
Approved
Investigational
Matched Description: … Tofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling ... It is approved by the FDA for treatment of moderate to severe rheumatoid arthritis that responds inadequately …
Matched Categories: … Antirheumatic Agents ... Bradycardia-Causing Agents ... Myelosuppressive Agents ... Immunosuppressive Agents ... Antineoplastic and Immunomodulating Agents …

Futibatinib

Futibatinib is an inhibitor of Fibroblast Growth Factor receptor (FGFR), which comprises a group of receptor tyrosine kinases that play a key role in cell proliferation, differentiation, migration, and survival. FGFR was investigated in oncology as a therapeutic target, as FGFR genomic aberrations and dysregulated FGFR signalling pathways are observed...
Approved
Investigational
Matched Description: … Futibatinib is an inhibitor of Fibroblast Growth Factor receptor (FGFR), which comprises a group of receptor ... [A253193,A253198] As a novel inhibitor of FGFR, futibatinib was first approved by the FDA in September …
Matched Categories: … Antineoplastic Agents ... Antineoplastic and Immunomodulating Agents …

Olutasidenib

Olutasidenib (FT-2102) is a selective and potent isocitrate dehydrogenase-1 (IDH1) inhibitor approved by the FDA in December 2022.[L44256,L44261] It is indicated for the treatment of relapsed or refractory acute myeloid leukemia (AML) in patients with a susceptible IDH1 mutation as determined by an FDA-approved test. IDH1 mutations are common in...
Approved
Investigational
Matched Description: … FDA-approved test. ... refractory acute myeloid leukemia (AML) in patients with a susceptible IDH1 mutation as determined by an ... intrahepatic cholangiocarcinoma, chondrosarcoma, and myelodysplastic syndromes (MDS), and they lead to an …
Matched Categories: … Antineoplastic Agents ... QTc Prolonging Agents ... Potential QTc-Prolonging Agents …

Cyclophosphamide

Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects,...
Approved
Investigational
Matched Description: … Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated …
Matched Categories: … Antineoplastic Agents ... Antirheumatic Agents ... Neurotoxic agents ... Myelosuppressive Agents ... Immunosuppressive Agents …

Nicotinamide

An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Approved
Investigational
Matched Description: … An important compound functioning as a component of the coenzyme NAD. …
Matched Mixtures name: … Kanga-B Vitamin B Group + C …
Matched Products: … An Adc Sp Intensive Moisture Essence …

Thiohexam

Thiohexam is a rubber cure accelerator. It is also a known allergen and dermatological sensitizer. Sensitivity to Thiohexam may be identified with a clinical patch test.
Approved
Experimental

Indapamide

The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor to all-cause mortality is hypertension. Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. Treatment for hypertension should include a number of lifestyle changes (ie. reduced...
Approved
Matched Description: … an estimated 25% of adults globally. ... intake) along with pharmacotherapy - it should be noted that treatment with several antihypertensive agents ... Indapamide is characterized by both a methylindoline and a sulfamoyl chlorobenzamide functional group …
Matched Categories: … Antihypertensive Agents ... Cardiovascular Agents ... Hypotensive Agents ... Natriuretic Agents ... QTc Prolonging Agents …

Kinetin

Kinetin is a cytokinin which are plant hormones promotes cell division and plant growth. It was shown to naturally exist in DNA of organisms including humans and various plants. While kinetin is used in tissue cultures to produce new plants, it is also found in cosmetic products as an anti-aging...
Approved
Matched Description: … anti-aging agents. ... kinetin is used in tissue cultures to produce new plants, it is also found in cosmetic products as an …

Mirtazapine

Mirtazapine is a tetracyclic piperazino-azepine antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994. This drug was first manufactured by Organon Inc., and received FDA approval in 1997 for the treatment of major depressive disorder.[T595, L6157] The effects of this...
Approved
Matched Description: … Mirtazapine is a tetracyclic _piperazino-azepine_ antidepressant agent that was initially approved for …
Matched Categories: … Antidepressive Agents ... Antidepressive Agents, Tetracyclic ... Antidepressive Agents, Second-Generation ... Antidepressive Agents Indicated for Depression ... Adrenergic Agents …

Doxepin

Doxepin is a psychotropic agent with antidepressant and anxiolytic properties. It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer corresponding to cidoxepin. Doxepin commonly produces a 5:1 (E):(Z) racemic mixture. In a strict sense, doxepin is not a tricyclic antidepressant but...
Approved
Investigational
Matched Description: … [L5977] Doxepin was developed by Pfizer and FDA approved in 1969 as an antidepressant. ... [L5971] However, in 2010 it was approved for the treatment of insomnia. …
Matched Categories: … Antidepressive Agents ... Antidepressive Agents, Tricyclic ... Antidepressive Agents Indicated for Depression ... Histamine Agents ... Serotonin Agents …

Ditiocarb zinc

Ditiocarb zinc, also known as Diethyldithiocarbamic acid zinc salt, is a known chelator for copper and zinc. It also a dermatological sensitizer and allergen. Sensitivity to ditiocarb zinc may be identified with a clinical patch test.
Approved
Matched Categories: … Chelating Agents ... Anti-Infective Agents ... Sequestering Agents ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Zinc dibutyldithiocarbamate

Zinc dibutyldithiocarbamate is a dermatological sensitizer and allergen. Sensitivity to zinc dibutyldithiocarbamate may be identified with a clinical patch test.
Approved
Experimental
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Displaying drugs 76 - 100 of 10312 in total