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Displaying drugs 1001 - 1025 of 1510 in total

Tasadenoturev

Investigational
Matched Synonyms: … adenovirus delta 24-RGD, an oncolytic adenovirus genetically modified for treatment of glioma …

Benzydamine

Benzydamine (also known as Tantum Verde or Difflam), available as the hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties. It is used topically for pain relief and anti-inflammatory treatment of the mouth, throat, or muscoskeletal system. Although the indazole analogue benzydamine is a...
Approved
Matched Description: … It is used topically for pain relief and anti-inflammatory treatment of the mouth, throat, or muscoskeletal ... hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and ... benzydamine is a non-steroidal anti-inflammatory drug (NSAID), it has various physicochemical properties and …
Matched Mixtures name: … Anti-inflammatory Lozenge (with antibacterial) (Eucalyptus and Menthol) ... Difflam plus ANAESTHETIC Sore Throat Lozenges (Sugar Free) Menthol and Eucalyptus Flavour ... FARHEX FORTE SPREY …
Matched Categories: … Topical Products for Joint and Muscular Pain ... Alimentary Tract and Metabolism ... Mouthwashes and Gargles ... Antiinflammatory and Antirheumatic Products ... Genito Urinary System and Sex Hormones …
Matched Products: … Tantum Verde forte - Mundspray ... BENZIRIN® FORTE 0.3% SOLUCIÓN BUCAL ... Difflam Forte Anti-Inflammatory Throat Spray …

10-formyl-5,8,10-trideazafolic acid

Experimental
Matched Name: … 10-formyl-5,8,10-trideazafolic acid …

(6R)-Folinic acid

Experimental
Matched Synonyms: … [6R]-5-formyl-5,6,7,8-tetrahydrofolate ... L-Glutamic acid, N-[4-[[[(6R)-2-amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino] ... N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl} …
Matched Iupac: … (2S)-2-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido …
Matched Categories: … Folic Acid and Derivatives …

Cisatracurium

Cisatracurium is a non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available in its salt form, cisatracurium besylate.[A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly used neuromuscular blocking agents in intensive care.[A253592,A253597]. Cisatracurium acts on cholinergic receptors, blocking neuromuscular transmission. This action is...
Approved
Investigational
Matched Description: … [A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly ... [A243416,A253592] Cisatracurium is an R-cis-R-cis isomer of [atracurium] and has approximately 3 times ... non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available in its salt form …
Matched Products: … Nimbex Forte Injection 150 mg/30 ml ... Cisatracurium-hameln 2 mg/ml solution for injection/infusion ... Cisatracurium Kabi 2 mg/ml solution for injection or infusion …

Dicloxacillin

One of the penicillins which is resistant to penicillinase.
Approved
Investigational
Vet approved
Matched Salts name: … Dicloxacillin sodium ... Dicloxacillin sodium anhydrous …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Dicloxacillin Sodium …

RU82197

Experimental
Matched Synonyms: … 4-[2-Acetylamino-2-(1-biphenyl-4-ylmethyl-2-oxo-azepan-3-ylcarbamoyl)-ethyl]-2-formyl-benzoic acid …

IFx-Hu2.0

IFx-Hu2.0 is an investigational cancer vaccine. It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a cationic polymer.
Investigational
Matched Synonyms: … Immunotherapeutic vaccine consisting of pAc/emm55, a plasmid DNA (pDNA), which codes for a modified immunogenic …

AVR-RD-05

AVR-RD-05 is a gene therapy comprising genetically modified autologous stem cells transduced ex vivo with a lentiviral vector encoding the human iduronate-2-sulfatase (IDS) enzyme. It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII).
Investigational
Matched Synonyms: … Ex vivo, lentiviral vector (LV)-mediated, genetically modified autologous cell therapy intended for the …
Matched Description: … It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII) …

Glucosamine

Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation. Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional benefits to nonsteroidal anti-inflammatory drugs treating the painful symptoms of OA. Glucosamine is commonly used over the counter as...
Approved
Investigational
Matched Description: … changes, and synovial membrane inflammation. ... Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone ... as a medical therapy varies due to contradictory and findings with unclear clinical significance during …
Matched Mixtures name: … Bee Venom Joint And Bone Therapy Drops ... Blackmores Joint Formula with Glucosamine and Chondroitin ... CARTICAP FOR …
Matched Salts name: … Glucosamine sulfate sodium chloride ... Glucosamine sulfate potassium chloride …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … PROSULF FORTE ... Donna Forte Capsule 500mg ... CUINE POWDER FOR ORAL SOLUTION …

Minnelide

Investigational
Matched Synonyms: … -one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-8b-methyl-6a-(1-methylethyl)-6-((phosphonooxy)methoxy)-, sodium …
Matched Iupac: … tetraoxaheptacyclo[11.7.0.0^{2,4}.0^{2,9}.0^{5,7}.0^{9,11}.0^{14,18}]icos-14(18)-en-8-yl]oxy}methyl phosphate …

Lipoic acid

A vitamin-like antioxidant.
Approved
Investigational
Nutraceutical
Matched Synonyms: … Thioctic acid D-form …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Various Alimentary Tract and Metabolism Products …

Sulbactam

Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus. When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.
Approved
Matched Description: … Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus. ... with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for …
Matched Mixtures name: … Ampicillin Sodium and Sulbactam Sodium ... Ampicillin Sodium and Sulbactam Sodium ... Ampicillin Sodium and Sulbactam Sodium …
Matched Salts name: … Sulbactam sodium …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … SULFACETAMIDA SODICA TOR 30% GOTAS OFTALMICAS …

Cefadroxil

Long-acting, broad-spectrum, water-soluble, cephalexin derivative.
Approved
Vet approved
Withdrawn
Matched Salts name: … Cefadroxil sodium …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … VOCEFA FORTE ... CEFFORD FORTE ... OPICEF FORTE …

Trastuzumab

Produced in CHO cell cultures, trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein (HER2). It is used as a treatment of human epidermal...
Approved
Investigational
Matched Description: … Trastuzumab binds to HER2 and suppresses cancer cell growth, proliferation, and survival directly and ... that the overexpression or gene amplification of HER2 has been found in about 20–30% of breast cancers and ... cancer, it is the second biosimilar approved in the U.S. for the treatment of cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... pertuzumab and trastuzumab ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … HERZUMA® 440MG POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION ... Herzuma (trastuzumab) 150 mg Powder for Concentrate for Solution for Infusion ... HERZUMA® 150MG POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION …

Cresol

Cresol is a hydroxytoluene that can be extracted naturally from coal tar or made synthetically. Pure cresol is a mixture of ortho-, meta-, and para- isomers. Cresols are precursors or synthetic intermediates to various other compounds and materials, including plastics, pesticides, pharmaceuticals, disinfectants, and dyes. Ingestion of cresol induces toxicity...
Approved
Matched Description: … concentrations normally found in the environment however, cresols do not pose any significant risk for ... pain, and/or vomiting. ... Ingestion of cresol induces toxicity in humans and can lead to burning of the mouth and throat, abdominal …
Matched Products: … Formo Cresol ... Buckleys Formo Cresol …

Methylprednisolone

Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s.[A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with...
Approved
Vet approved
Matched Mixtures name: … Methylprednisolone Sodium Succinate for Injection, USP ... Methylprednisolone Sodium Succinate for Injection, USP …
Matched Categories: … Sex Hormones and Insulins ... methylprednisolone and antibiotics ... methylprednisolone and antiinfectives ... methylprednisolone and antiinfectives ... Ophthalmological and Otological Preparations …
Matched Products: … METHYLPREDNISOLONE POWDER FOR SOLUTION FOR INJECTION 500mg ... METILPREDNISOLONA SODIO SUCCINATO. METIL PREDNISOLONA 500 MG. PARA RECONSTITUIR A 4 ML. …

Polatuzumab vedotin

Polatuzumab vedotin is a CD79b-directed antibody-drug conjugate that delivers monomethyl auristatin E (MMAE), an anti-mitotic agent, to cancer cells. The drug consists of three components - a humanized immunoglobulin G1 (IgG1) monoclonal antibody specific for human CD79b (polatuzumab), MMAE, and protease-cleavable linker called maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl (mc-vc-PAB) that covalently attaches MMAE to...
Approved
Investigational
Matched Description: … [L6658] Polatuzumab vedotin was granted accelerated FDA approval on June 10, 2019 [A254936] and was ... human CD79b (polatuzumab), MMAE, and protease-cleavable linker called maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl ... drug consists of three components - a humanized immunoglobulin G1 (IgG1) monoclonal antibody specific for …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … POLIVY POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 140MG ... POLIVY POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 30MG ... POLIVY 140mg Powder For Concentrate For Solution For Infusion …

Trastuzumab emtansine

Trastuzumab emtansine, formerly called Trastuzumab-DM1 (T-DM1) is a first-in-class HER2 antibody drug conjugate (ADC) comprised of Genentech's trastuzumab antibody linked to ImmunoGen's cell-killing agent, DM1. T-DM1 combines two strategies-- anti-HER2 activity and targeted intracellular delivery of the potent anti-microtubule agent, DM1 (a maytansine derivative)--to produce cell cycle arrest and apoptosis....
Approved
Investigational
Matched Description: … Trastuzumab emtansine is marketed under the brand name Kadcyla and is indicated for use in HER2-positive ... , metastatic breast cancer patients who have already used taxane and/or trastuzumab for metastatic disease ... First that trastuzumab emtansine and trastuzumab cannot be interchanged. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … KADCYLA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/VIAL ... KADCYLA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 160MG/VIAL ... Kadcyla 160 mg powder for concentrate for solution for infusion …

Siltuximab

Siltuximab is a chimeric (human-mouse) monoclonal immunoglobulin G1-kappa antibody produced in a Chinese hamster ovary (CHO) cell line by recombinant DNA technology. Siltuximab prevents the binding of IL-6 to soluble and membrane-bound IL-6 receptors by forming high affinity complexes with human interleukin-6 (IL-6). Its use is indicated for the treatment...
Approved
Investigational
Matched Description: … Siltuximab prevents the binding of IL-6 to soluble and membrane-bound IL-6 receptors by forming high ... who are human immunodeficiency virus (HIV) negative and human herpesvirus-8 (HHV-8) negative. ... MCD is a rare blood disorder caused by dysregulated IL-6 production, proliferation of lymphocytes, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Sylvant 400mg Powder for Concentrate for Solution for Infusion ... Sylvant 100mg Powder for Concentrate for Solution for Infusion ... SYLVANT POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/VIAL …

ABSK-012

Investigational
Matched Synonyms: … 3-(5-cyano-4-(cyclopropylamino)pyridin-2-yl)-1-(6-formyl-5-((4-methyl-2-oxopiperazin-1-yl)methyl)pyridin ... N′-[5-Cyano-4-(cyclopropylamino)-2-pyridinyl]-N-[6-formyl-5-[(4-methyl-2-oxo-1-piperazinyl)methyl]-2- ... Urea, N′-[5-cyano-4-(cyclopropylamino)-2-pyridinyl]-N-[6-formyl-5-[(4-methyl-2-oxo-1-piperazinyl)methyl …
Matched Iupac: … 3-[5-cyano-4-(cyclopropylamino)pyridin-2-yl]-1-{6-formyl-5-[(4-methyl-2-oxopiperazin-1-yl)methyl]pyridin …

Brentuximab vedotin

Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 antibody with the drug monomethyl auristatin E (MMAE). It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic large-cell lymphoma. Brentuximab vedotin was initially approved in 2011. In January 2012, the...
Approved
Investigational
Matched Description: … This demonstrates meaningful progress in treatment for patients affected by this disease.[L1739] ... Lymphoma may begin anywhere in the body and can spread to nearby lymph nodes. ... It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic large-cell …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … ADCETRIS 50 MG (POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION) ... POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 50MG/VIAL ... Adcetris 50mg, powder for concentrate for solution for infusion …

Polyvinyl alcohol

Polyvinyl alcohol is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol. It has varying roles in commercial and industrial applications such as papermaking, textiles, and printing. Polyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes .
Approved
Matched Description: … It has varying roles in commercial and industrial applications such as papermaking, textiles, and printing …
Matched Mixtures name: … Murine Tears for Dry Eyes ... Murine Plus for Dry Eyes Redness Relief …
Matched Products: … Liquifilm Forte 3% ... Artificial Tears for Dry Eyes …

Simoctocog alfa

Simoctocog alfa is a recombinant B-domain deleted (BDD) rFVIII produced in genetically modified human embryonic kidney (HEK) 293F cells. The harvested product is concentrated and purified by a series of chromatography steps. It is an antihemorrhagic agent used as a replacement therapy in individuals with Haemophilia A who lack the...
Approved
Matched Description: … The harvested product is concentrated and purified by a series of chromatography steps. ... + A3-C1-C2 whereas the B-domain, present in the full-length plasma-derived FVIII, has been deleted and ... potentially immunogenic glycosylation patterns found in non-human cell lines led to decreased immunogenicity and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Nuwiq 250IU Powder for Solution for Injection ... Nuwiq 500IU Powder for Solution for Injection ... Nuwiq 1000IU Powder for Solution for Injection …

Archexin

Investigational
Matched Synonyms: … 5'-DG-DC-T-DG-DC-DA-T-DG-DA-T-DC-T-DC-DC-T-T-DG-DG-DC-DG-3', SODIUM PHOSPHOTHIOATE …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Displaying drugs 1001 - 1025 of 1510 in total