Displaying drugs 1151 - 1175 of 1372 in total
Tadalafil
Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. In contrast to other PDE5 inhibitors...
Approved
Investigational
Matched Synonyms: … (6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido( …
Matched Description: … that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and ... [L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. ... In contrast to other PDE5 inhibitors like [sildenafil], tadalafil has greater selectivity for PDE5 and …
Matched Categories: … tamsulosin and tadalafil ... ambrisentan and tadalafil ... macitentan and tadalafil ... finasteride and tadalafil ... Genito Urinary System and Sex Hormones …
Matched Products: … DEPARTON 20 MG FILM KAPLI TABLET, 120 ADET ... TADARTER 20 MG FİLM KAPLI TABLET , 120 ADET ... TADAL 1A PHARMA PAH 20MG …
Matched Description: … that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and ... [L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. ... In contrast to other PDE5 inhibitors like [sildenafil], tadalafil has greater selectivity for PDE5 and …
Matched Categories: … tamsulosin and tadalafil ... ambrisentan and tadalafil ... macitentan and tadalafil ... finasteride and tadalafil ... Genito Urinary System and Sex Hormones …
Matched Products: … DEPARTON 20 MG FILM KAPLI TABLET, 120 ADET ... TADARTER 20 MG FİLM KAPLI TABLET , 120 ADET ... TADAL 1A PHARMA PAH 20MG …
Catridecacog
Coagulation Factor XIII A-Subunit (Recombinant), also known as catridecacog, is a recombinant form of the Factor XIII-A2 homodimer composed of two factor XIII (FXIII) A-subunits [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key coagulation factor is essential...
Approved
Matched Synonyms: … Blood Coagulation Factor XIII (Synthetic Human A-Chain Precursor) ... Human Factor XIII (A2) homodimer (allele F13A*1B), recombinant DNA origin …
Matched Description: … then isolated, the human form is isolated from pooled human plasma. ... and maintenance of hemostasis [A18581]. ... bleeding disorder, exogenous replacement of this key coagulation factor is essential for management and …
Matched Categories: … Blood and Blood Forming Organs …
Matched Description: … then isolated, the human form is isolated from pooled human plasma. ... and maintenance of hemostasis [A18581]. ... bleeding disorder, exogenous replacement of this key coagulation factor is essential for management and …
Matched Categories: … Blood and Blood Forming Organs …
Cipaglucosidase alfa
Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in GAA. Other types of enzyme replacement therapy for the treatment of Pompe disease include alglucosidase alfa and avalglucosidase alfa. Cipaglucosidase...
Approved
Investigational
Matched Synonyms: … Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphate …
Matched Description: … types of enzyme replacement therapy for the treatment of Pompe disease include [alglucosidase alfa] and ... cipaglucosidase alfa be granted marketing authorization for the treatment of Pompe disease,[L45275] and ... Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Description: … types of enzyme replacement therapy for the treatment of Pompe disease include [alglucosidase alfa] and ... cipaglucosidase alfa be granted marketing authorization for the treatment of Pompe disease,[L45275] and ... Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Roxithromycin
Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar to erythromycin, azithromycin, or clarithromycin. It was shown to be more effective against certain Gram-negative bacteria, particularly Legionella pneumophila. Roxithromycin exerts its antibacterial action by binding to the bacterial ribosome and interfering with bacterial protein synthesis. It is...
Approved
Investigational
Withdrawn
Matched Iupac: … (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy …
Matched Description: … Roxithromycin exerts its antibacterial action by binding to the bacterial ribosome and interfering with ... Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar ... It is marketed in Australia as a treatment for respiratory tract, urinary and soft tissue infections. …
Matched Categories: … Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins …
Matched Products: … ROXI 150 1A PHARMA ... ROXI 300 1A PHARMA …
Matched Description: … Roxithromycin exerts its antibacterial action by binding to the bacterial ribosome and interfering with ... Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar ... It is marketed in Australia as a treatment for respiratory tract, urinary and soft tissue infections. …
Matched Categories: … Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins …
Matched Products: … ROXI 150 1A PHARMA ... ROXI 300 1A PHARMA …
Rasagiline
Rasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
Approved
Matched Description: … Rasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's …
Matched Categories: … Serotonin Agents ... Serotonin Modulators ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … RASAGILIN 1A PHARMA 1MG ... Rasagilin 1A Pharma 1 mg - Tabletten …
Matched Categories: … Serotonin Agents ... Serotonin Modulators ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … RASAGILIN 1A PHARMA 1MG ... Rasagilin 1A Pharma 1 mg - Tabletten …
Ambrisentan
Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension. It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ability and delay clinical worsening. In addition, it is approved in the...
Approved
Investigational
Matched Description: … ability and delay clinical worsening. ... It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ... States for use in combination with tadalafil to reduce the risks of disease progression, hospitalization and …
Matched Categories: … ambrisentan and tadalafil …
Matched Products: … AMBRISEN 1A PHARMA 5MG ... AMBRISEN 1A PHARMA 10MG …
Matched Categories: … ambrisentan and tadalafil …
Matched Products: … AMBRISEN 1A PHARMA 5MG ... AMBRISEN 1A PHARMA 10MG …
Riluzole
A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis. Riluzole is marketed as Rilutek by Sanofi.
Approved
Investigational
Matched Description: … A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong …
Matched Products: … RILUZOL 1A PHARMA 50MG …
Matched Products: … RILUZOL 1A PHARMA 50MG …
Gabapentin
Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures[A186277,A186143] - today it is also widely used to treat neuropathic...
Approved
Investigational
Matched Description: … It is structurally and functionally related to another GABA derivative, [pregabalin]. ... other anti-epileptics, such as a relatively benign adverse effect profile, wide therapeutic index, and ... Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid ([GABA …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Gabapentin and Prodrugs …
Matched Products: … GABAPENTIN 1A PHARMA 100MG ... GABAPENTIN 1A PHARMA 300MG ... GABAPENTIN 1A PHARMA 400MG …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Gabapentin and Prodrugs …
Matched Products: … GABAPENTIN 1A PHARMA 100MG ... GABAPENTIN 1A PHARMA 300MG ... GABAPENTIN 1A PHARMA 400MG …
Basic Fibroblast Growth Factor
Basic Fibroblast Growth Factor (bFGF) is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of physiologic angiogenesis. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative...
Investigational
Matched Synonyms: … Basic fibroblast growth factor, recombinant human, KCB-1 ... Recombinant human basic fibroblast growth factor, KCB-1 …
Matched Description: … single-chain polypeptide growth factor that plays a significant role in the process of wound healing and ... It has a 55 percent amino acid residue identity to Fibroblast Growth Factor 1 and has potent heparin-binding ... growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … single-chain polypeptide growth factor that plays a significant role in the process of wound healing and ... It has a 55 percent amino acid residue identity to Fibroblast Growth Factor 1 and has potent heparin-binding ... growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Escitalopram
Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic citalopram. It is used to restore serotonergic function in the treatment of depression and anxiety.[L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with...
Approved
Matched Description: … Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic [citalopram ... [A185420] It is used to restore serotonergic function in the treatment of depression and anxiety. ... L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and …
Matched Categories: … Serotonin Agents ... Serotonin Modulators ... Selective Serotonin Reuptake Inhibitors ... Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … ESCITALOPRAM 1A 20MG/ML ... ESCITALOPRAM 1A PHARMA 5MG ... ESCITALOPRAM 1A PHARMA10MG …
Matched Categories: … Serotonin Agents ... Serotonin Modulators ... Selective Serotonin Reuptake Inhibitors ... Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … ESCITALOPRAM 1A 20MG/ML ... ESCITALOPRAM 1A PHARMA 5MG ... ESCITALOPRAM 1A PHARMA10MG …
Dezamizumab
Dezamizumab is under investigation in clinical trial NCT03417830 (Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging).
Investigational
Matched Synonyms: … recombinant monoclonal antibody to human serum amyloid P component ... ), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL GSK2398852 LIGHT CHAIN, DIMER ... IMMUNOGLOBULIN G1, ANTI-(SERUM AMYLOID P PROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL GSK2398852 HEAVY CHAIN …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Febuxostat
Febuxostat is a non-purine xanthine oxidase (XO) inhibitor. In early 2008, febuxostat was granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and gout. In the following year, the FDA for approved febuxostat for use in the chronic management of hyperuricemia in adult patients with gout...
Approved
Matched Description: … granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and ... that is caused by the accumulation of uric acid crystal in or around a joint, leading to inflammation and ... further deposition of uric acid crystal deposition in bones, joints, tissues, and other organs in the …
Matched Products: … FEBUXOSTAT 1A PHARMA 80MG ... FEBUXOSTAT 1A PHARMA 120MG ... ADENURIC 120 MG …
Matched Products: … FEBUXOSTAT 1A PHARMA 80MG ... FEBUXOSTAT 1A PHARMA 120MG ... ADENURIC 120 MG …
Reveglucosidase alfa
Investigational
Matched Synonyms: … Des-(2-7)-human insulin-like growth factor ii fusion protein with glycyl-l-alanyl-l-prolyl-human lysosomal …
Botaretigene sparoparvovec
Investigational
Matched Synonyms: … DNA (RECOMBINANT PSEUDOTYPED ADENO-ASSOCIATED VIRUS 5 VECTOR AAV-RPGR HUMAN RHODOPSIN KINASE PROMOTER ... FRAGMENT-REGULATED HUMAN RETINITIS PIGMENTOSA GTPASE REGULATOR RPGR-ORF15 ISOFORM GENE VARIANT PLUS …
Imatinib
Imatinib is a small molecule kinase inhibitor that revolutionized the treatment of cancer, particularly chronic myeloid leukemia, in 2001. It was deemed a "miracle drug" due to its clinical success, as oncologist Dr. Brian noted that "complete hematologic responses were observed in 53 of 54 patients with CML treated with...
Approved
Matched Description: … responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more and ... [L42220]
Imatinib was approved on February 1st ,2001 by the FDA and November 7th, 2001 by the EMA …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Benzamides and benzamide derivatives …
Matched Products: … IMATINIB 1A PHARMA 100MG ... IMATINIB 1A PHARMA 400MG ... Imatinib 1A Pharma 100 mg – Filmtabletten …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Benzamides and benzamide derivatives …
Matched Products: … IMATINIB 1A PHARMA 100MG ... IMATINIB 1A PHARMA 400MG ... Imatinib 1A Pharma 100 mg – Filmtabletten …
Minocycline
Minocycline was first described in the literacture in 1966. It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria. Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines. Minocycline was granted FDA approval...
Approved
Investigational
Matched Synonyms: … (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene …
Matched Iupac: … (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene …
Matched Description: … [A190681] It is a second generation tetracycline antibiotic that is active against gram-negative and …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … MINOCYCLIN 1A PHARMA 50MG …
Matched Iupac: … (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene …
Matched Description: … [A190681] It is a second generation tetracycline antibiotic that is active against gram-negative and …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … MINOCYCLIN 1A PHARMA 50MG …
(5E)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE
Experimental
Matched Name: … (5E)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE …
Matched Iupac: … (5E)-12-chloro-13,15-dihydroxy-1,3,4,7,8,9,10,11-octahydro-2-benzoxacyclotridecine-1,10-dione …
Matched Iupac: … (5E)-12-chloro-13,15-dihydroxy-1,3,4,7,8,9,10,11-octahydro-2-benzoxacyclotridecine-1,10-dione …
Rizatriptan
Rizatriptan is a second-generation triptan and a selective 5-HT1B and 5-HT1D receptor agonist. Used in the treatment of migraines, rizatriptan was first approved in the US in 1998. Rizatriptan is available in oral tablets, orally disintegrating tablets (wafers), and oral film formulations.
Approved
Matched Description: … Rizatriptan is a second-generation triptan [A258918] and a selective 5-HT1B and 5-HT1D receptor ... [L46018] Rizatriptan is available in oral tablets, orally disintegrating tablets (wafers), and oral film …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist ... Serotonin Agents ... Serotonin Modulators ... Serotonin Receptor Agonists ... Selective Serotonin Agonists …
Matched Products: … RIZATRIPTAN LIN 1A PHA 5MG ... RIZATRIPTAN LIN 1A PHA10MG …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist ... Serotonin Agents ... Serotonin Modulators ... Serotonin Receptor Agonists ... Selective Serotonin Agonists …
Matched Products: … RIZATRIPTAN LIN 1A PHA 5MG ... RIZATRIPTAN LIN 1A PHA10MG …
Terazosin
Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label] . Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate .
Approved
Matched Description: … quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and ... adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … TERAZOSIN 1A PHARMA 2MG ... TERAZOSIN 1A PHARMA 5MG …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … TERAZOSIN 1A PHARMA 2MG ... TERAZOSIN 1A PHARMA 5MG …
Tisotumab vedotin
Tisotumab vedotin is a tissue factor-directed antibody-drug conjugate (ADC) comprised of an anti-tissue factor (TF) human IgG1-kappa antibody conjugated to monomethyl auristatin E (MMAE), a microtubule-disrupting agent, via a protease-cleavable valine-citrulline linker. Each monoclonal antibody molecule carries an average of four MMAE molecules. Tisotumab vedotin is the first TF-directed ADC...
Approved
Matched Synonyms: … HuMax-TF-ADC …
Matched Description: … vedotin is a tissue factor-directed antibody-drug conjugate (ADC) comprised of an anti-tissue factor (TF) human ... head and neck cancers. ... tumor-associated angiogenesis, progression, and metastasis for tumor survival. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Description: … vedotin is a tissue factor-directed antibody-drug conjugate (ADC) comprised of an anti-tissue factor (TF) human ... head and neck cancers. ... tumor-associated angiogenesis, progression, and metastasis for tumor survival. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Dental Mesenchymal Pulp Stem Cells
Dental pulp is a soft, connective tissue present in the dental crown of both third molar and first premolar teeth. Dental pulp stem cells (DPSCs) exhibit fibro-blast like plasticity and adherent properties. They are harvested through surgical extraction of wisdom teeth from adults; this procedure is favoured as it is...
Investigational
Matched Synonyms: … Allogenic Human Dental Pulp Stem Cells …
Matched Description: … DPSCs can remain stable in media once extracted, and have a high proliferation and regeneration capacity ... DPSCs have multiple properties, and express surface antigens like CD90, CD29, and CD105 but not CD14 ... Dental pulp is a soft, connective tissue present in the dental crown of both third molar and first premolar …
Matched Description: … DPSCs can remain stable in media once extracted, and have a high proliferation and regeneration capacity ... DPSCs have multiple properties, and express surface antigens like CD90, CD29, and CD105 but not CD14 ... Dental pulp is a soft, connective tissue present in the dental crown of both third molar and first premolar …
TOL-101
Investigational
Matched Synonyms: … Murine IgM monoclonal antibody specific for the human alpha, beta T cell receptor …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
RGX-121
RGX-121 is designed to use the NAV AAV9 vector to deliver the human iduronate-2-sulfatase gene to the central nervous system.
Investigational
Matched Synonyms: … Non-replicating recombinant adeno-associated virus (AAV) vector of serotype 9 expressing human iduronate …
Matched Name: … RGX-121 …
Matched Description: … RGX-121 is designed to use the NAV AAV9 vector to deliver the human iduronate-2-sulfatase gene to the …
Matched Name: … RGX-121 …
Matched Description: … RGX-121 is designed to use the NAV AAV9 vector to deliver the human iduronate-2-sulfatase gene to the …
AMT-130
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 5 encoding a microRNA targeted to human Huntingtin gene …
CypCaps
Investigational
Matched Synonyms: … Cytochrome P450 isoform 2B1 gene transfected human embryonic kidney 293 cells encapsulated in polymeric …
Displaying drugs 1151 - 1175 of 1372 in total